SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition
Kim, Eunhee, Ilagan, Janine O., Liang, Yang, Daubner, Gerrit M., Lee, Stanley C.-W., Ramakrishnan, Aravind, Li, Yue, Chung, Young Rock +17 more·2015·Cancer Cell
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- Myelodysplastic syndrome patient-derived xenografts: from no options to manyChristophé Côme, Alexander Balhuizen, Dominique A. Bonnet, Bo Torben Porse · 2020 · Haematologica
- Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancerJian Han, Ömer An, Xi Ren, Yangyang Song, Sze Jing Tang, Haoqing Shen, Xinyu Ke, Vanessa Hui En Ng, Daryl Jin Tai Tay, Hui Qing Tan et al. · 2022 · Nature Communications
- Molecular Pathogenesis of Myeloproliferative NeoplasmsBenjamin Rolles, Ann Mullally · 2022 · Current Hematologic Malignancy Reports
- The prognostic implication of SRSF2 mutations in Chinese patients with acute myeloid leukemiaJing Chun Yang, Dong‐ming Yao, Ji‐chun Ma, Lei Yang, Hong Yan Guo, Xiang‐mei Wen, Gao-fei Xiao, Zhen Yu Qian, Jiang Lin, Jun Qian · 2016 · Tumor Biology
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- RNA splicing, cell signaling, and response to therapiesChérine Abou Fayçal, Sylvie Gazzéri, Béatrice Eymin · 2015 · Current Opinion in Oncology
- Gene Regulatory Network Perturbation by Genetic and Epigenetic VariationYongsheng Li, Daniel James McGrail, Juan Xu, Gordon Brent Mills, Nidhi Sahni, S. Stephen Yi · 2018 · Trends in Biochemical Sciences
- Distinct and convergent consequences of splice factor mutations in myelodysplastic syndromesVikas Madan, Jia Li, Siqin Zhou, Weoi Woon Teoh, Lin Han, Manja Meggendorfer, Luca Malcovati, Mario Cazzola, Seishi Ogawa, Torsten Haferlach et al. · 2019 · American Journal of Hematology
- Emerging treatments for myelodysplastic syndromes: Biological rationales and clinical translationJuan José Rodríguez‐Sevilla, Vera Ademà, Guillermo Garcia‐Manero, Simona Colla · 2023 · Cell Reports Medicine
- Targeting alternative splicing in cancer immunotherapyNan Han, Zhaoqi Liu · 2023 · Frontiers in Cell and Developmental Biology
- Splicing Anomalies in Myeloproliferative Neoplasms: Paving the Way for New Therapeutic VenuesMarie Hautin, Clélia Mornet, Aurélie Chauveau, Delphine G. Bernard, Laurent Corcos, Éric Lippert · 2020 · Cancers
- Genomic heterogeneity in myeloproliferative neoplasms and applications to clinical practiceJoe Lee, Anna L. Godfrey, Jyoti Nangalia · 2020 · Blood Reviews
- Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in miceSanghyun Peter Kim, Sridhar Nonavinkere Srivatsan, Monique Chavez, Cara Lunn Shirai, Brian S. White, Tanzir Ahmed, Michael O. Alberti, Jin Shao, Ryan M. Nunley, Lynn S. White et al. · 2021 · Cell Reports
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