Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 434

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Integrated Molecular Characterization of Uterine Carcinosarcoma

Open access
Cherniack, Andrew D., Shen, Hui, Walter, Vonn, Stewart, Chip, Murray, Bradley A., Bowlby, Reanne, Hu, Xin, Ling, Shiyun, Soslow, Robert A., Broaddus, Russell R., Zuna, Rosemary E., Robertson, Gordon, Laird, Peter W., Kucherlapati, Raju, Mills, Gordon B., Akbani, Rehan, Ally, Adrian, Auman, J. Todd, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Beroukhim, Rameen, Bodenheimer, Tom, Bogomolniy, Faina, Boice, Lori, Bootwalla, Moiz S., Bowen, Jay, Bowlby, Reanne, Broaddus, Russell, Brooks, Denise, Carlsen, Rebecca, Cherniack, Andrew D., Cho, Juok, Chuah, Eric, Chudamani, Sudha, Cibulskis, Kristian, Cline, Melissa, Dao, Fanny, David, Mutch, Demchok, John A., Dhalla, Noreen, Dowdy, Sean, Felau, Ina, Ferguson, Martin L., Frazer, Scott, Frick, Jessica, Gabriel, Stacey, Gastier-Foster, Julie M., Gehlenborg, Nils, Gerken, Mark, Getz, Gad, Gupta, Manaswi, Haussler, David, Hayes, D. Neil, Heiman, David I., Hess, Julian, Hoadley, Katherine A., Hoffmann, Robert, Holt, Robert A., Hoyle, Alan P., Hu, Xin, Huang, Mei, Hutter, Carolyn M., Jefferys, Stuart R., Jones, Steven J.M., Jones, Corbin D., Kanchi, Rupa S., Kandoth, Cyriac, Kasaian, Katayoon, Kerr, Sarah, Kim, Jaegil, Lai, Phillip H., Laird, Peter W., Lander, Eric, Lawrence, Michael S., Lee, Darlene, Leraas, Kristen M., Leshchiner, Ignaty, Levine, Douglas A., Lichtenberg, Tara M., Lin, Pei, Ling, Shiyun, Liu, Jia, Liu, Wenbin, Liu, Yuexin, Lolla, Laxmi, Lu, Yiling, Ma, Yussanne, Maglinte, Dennis T., Marra, Marco A., Mayo, Michael, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Mills, Gordon B., Moore, Richard A., Mose, Lisle E., Mungall, Andrew J., Mungall, Karen, Murray, Bradley A., Naresh, Rashi, Noble, Michael S., Olvera, Narciso, Parker, Joel S., Perou, Charles M., Perou, Amy H., Pihl, Todd, Radenbaugh, Amie J., Ramirez, Nilsa C., Rathmell, W. Kimryn, Roach, Jeffrey, Robertson, A. Gordon, Sadeghi, Sara, Saksena, Gordon, Salvesen, Helga B., Schein, Jacqueline E., Schumacher, Steven E., Shen, Hui, Sheth, Margi, Shi, Yan, Shih, Juliann, Simons, Janae V., Sipahimalani, Payal, Skelly, Tara, Sofia, Heidi J., Soloway, Matthew G., Soslow, Robert A., Sougnez, Carrie, Stewart, Chip, Sun, Charlie, Tam, Angela, Tan, Donghui, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh B., Tse, Kane, Tseng, Jill, Van Den Berg, David J., Veluvolu, Umadevi, Verhaak, Roel G.W., Voet, Doug, von Bismarck, Amanda, Walter, Vonn, Wan, Yunhu, Wang, Zhining, Wang, Chen, Weinstein, John N., Weisenberger, Daniel J., Wilkerson, Matthew D., Winterhoff, Boris, Wise, Lisa, Wong, Tina, Wu, Ye, Yang, Liming, Zenklusen, Jean C., Zhang, Jiashan (Julia), Zhang, Hailei, Zhang, Wei, Zhu, Jing-chun, Zmuda, Erik, Zuna, Rosemary E., Weinstein, John N., Zhang, Jiashan, Akbani, Rehan, Levine, Douglas A.·2017·Cancer Cell
DOI 10.1016/j.ccell.2017.02.010
Open this paper in CoChat — free account

Abstract

Summary We performed genomic, epigenomic, transcriptomic and proteomic characterizations of uterine carcinosarcomas (UCSs). Cohort samples had extensive copy number alterations and highly recurrent somatic mutations. Frequent mutations were found in TP53, PTEN, PIK3CA, PPP2R1A, FBXW7 and KRAS, similar to endometrioid and serous uterine carcinomas. Transcriptome sequencing identified a strong epithelial-to-mesenchymal transition (EMT) gene signature in a subset of cases that was attributable to epigenetic alterations at microRNA promoters. The range of EMT scores in UCS was the largest amongst all tumor types studied via The Cancer Genome Atlas. UCSs shared proteomic features with gynecologic carcinomas and sarcomas with intermediate EMT features. Multiple somatic mutations and copy number alterations in genes that are therapeutic targets were identified.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.ccell.2017.02.010

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 40 references

Cited by

See all 434

Metadata

Authors
Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Broaddus, R., Brooks, D., Carlsen, R., Cherniack, A. D., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Hu, X., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Laird, P. W., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Murray, B. A., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Shen, H., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Soslow, R. A., Sougnez, C., Stewart, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Walter, V., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J. (., Zhang, H., Zhang, W., Zhu, J.-C., Zmuda, E., Zuna, R. E., Weinstein, J. N., Zhang, J., Akbani, R., & Levine, D. A.
Venue
Cancer Cell
Publisher
Elsevier BV
Published
2017-03
Volume
31
Issue
3
Pages
411-423
ISSN
1535-6108 (ISSN-L)
DOI
10.1016/j.ccell.2017.02.010
OpenAlex
W2595991414
Cited by
434
References
40
FWCI
40.18
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Integrated Molecular Characterization of Uterine Carcinosarcoma. https://app.cochat.ai/papers/10.1016/j.ccell.2017.02.010
The paper
Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., . . . Levine, D. A. (2017). Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. https://doi.org/10.1016/j.ccell.2017.02.010

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.