Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling
Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F. +19 more·2017·Cancer Cell
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- Systematic analysis of hippo pathway signaling identifies TEAD1 as a transcriptional regulator of neuroendocrine prostate cancerLisha G. Brown, Ilsa M. Coleman, Tony LH Chu, Erolcan Sayar, Radhika A. Patel, Brian P. Hanratty, Mohamed Adil, Dapei Li, Yongtao Li, Holly M. Nguyen et al. · 2026 · Neoplasia
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- A non-enzymatic role for METTL3 as an Androgen Receptor co-regulator that promotes prostate cancer proliferationRaymond J. Kostlan, John T. Phoenix, Audris Budreika, Carli D. Deegan, Marina G. Ferrari, Elise T Warren, Pushpinder Bawa, Charles S Rogers, Divya Dureja, M Obaidulla Ibne Ali et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Tumor-associated macrophages and lineage plasticity in prostate cancer: from established myeloid programs to emerging spatial hypothesesJia Li, Jinling Li, Y Zhao, Yuanqi Yu, Xiaolu Cui · 2026 · Frontiers in Immunology
- An Integrated Preclinical Platform for Lethal Neuroendocrine Prostate Cancer from Rapid Autopsy Bone and Liver MetastasesBorum Ryu, Thomas C. Caffrey, Sriya Sridhar, Catherine S. Johnson, Ramia J. Salloom, Kabhilan Mohan, Grace Waldron, Amanda Robotham, Ethan M Wilcox, Diane L. Costanzo-Garvey et al. · 2026 · SSRN Electronic Journal
- Enzalutamide promotes an early plasticity-associated transcriptional state without terminal neuroendocrine differentiation in prostate cancer cellsRyuta Watanabe, Mami Chosei, Haruna Arai, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika · 2026 · Frontiers in Oncology
- The FGFRL1–FASN axis regulates neuroendocrine lineage transdifferentiation by modulating fatty acid synthesis in AR pathway-independent prostate cancerYupeng Chen, Jiarun Lai, Jian Chen, Ziqing Zhou, Qianfeng Xu, Rui Zhou, Jinchuang Li, Yusen Long, Ailiyaerjiang Wureyimu, Jiaming Su et al. · 2026 · Cancer Letters
- Development and Validation of a Treatment-Specific Prognostic Model for Overall Survival in Patients with Metastatic Castration-Sensitive Prostate Cancer Treated with First-Line Apalutamide: A Multicenter Real-World StudyShin Kobayashi, Takuma Narita, Kotona Miyauchi, Shun Morishita, Naoki Fujita, Daiki Kikuchi, Noriyuki Abe, Miyu Ohtani, Naoki Wada, Shingo Hatakeyama et al. · 2026 · Research Square
- The Great Escape: the systems biology of endocrine resistance and lineage plasticityChristo Philip C. Dragnev, Zirui Fu, Sida Huang, Curtis J. Perry, Adriana Matutino Kahn, Michaela Ann Dinan, Wei Shen Tan, Michael S. Leapman, David A. Braun, Joshua Warrick et al. · 2026 · Endocrine Related Cancer
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- Comparative Assessment of METastasis Reporting and Data System for Prostate Cancer Versus Prostate Cancer Clinical Trials Working Group 3 Criteria in Assessing Treatment Response in Patients with Metastatic Castration-resistant Prostate CancerLuca Russo, Ossian Longoria, Silvia Bottazzi, Núria Porta, Katie Biscombe, Samuel Joseph Withey, Giacomo Avesani, Katarzyna Abramowicz, Matthew D. Blackledge, Luca D’Erme et al. · 2026 · European Urology Open Science
- Reprogramming the Evolution of High-Risk Prostate Cancer: Multidisciplinary Strategies to Delay Castration ResistanceYounghun Sim, Jae Won Choi, Dong Seob Kim, Jeong Hyun Kim, Sung Goo Yoon, Jung Ki Jo · 2026 · Journal of Clinical Medicine
- IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage statesDimitrios Doultsinos, Ingrid Tomljanović, Eleftherios Pilalis, Sophia M. Abusamra, Mohammed Alshalalfa, Romuald Parmentier, Vidhula R. Ahire, Imogen Bridges, Sandy Figiel, Joanna Hester et al. · 2026 · EMBO Molecular Medicine
- RUNX1T1 drives stem-like small-cell neuroendocrine prostate cancer identityZiqin Wang, Hyeryeon Jung, Changhyeon Hong, Nancy Chen, Yunsol Jo, Issac Jung, Taeeun Kim, Gina Lee, Keaton Chien, Ming Chen et al. · 2026 · Frontiers in Cell and Developmental Biology
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- Neuromedin U ‘innervation’ reprograms myeloid immunosuppression in neuroendocrine prostate cancerMichela Perego, Jozef Madžo, Andrew V. Kossenkov, Firdevs Cansu Atilgan, Marcella Tazzari, Maria Maddalena Tumedei, Francesco Limarzi, Cristian Lolli, Giorgia Gurioli, Alessandro Fatatis et al. · 2026 · Oncogene
- CXCR4-centred signalling network rewiring distinguishes primary and metastatic prostate cancer: A systems-level digital twin frameworkRadosław Dzik, Joanna Chwał, Ewaryst Tkacz · 2026 · European Journal of Cell Biology
- Cryo-EM structure-based discovery of etravirine as a specific inhibitor of PRMT5/pICln protein-protein interaction for prostate cancer treatmentZhixia Chi, Xueyong Xu, Zhihang Shen, Xuehong Deng, Bennett D. Elzey, Chenglong Li, Wen Jiang, Chang‐Deng Hu · 2026 · Journal of Enzyme Inhibition and Medicinal Chemistry
- Castration-resistant prostate cancer as an adaptive tumor ecosystem: coupling tumor evolution with microenvironmental reprogrammingSiliang Wang, Xinyi Xu, Minghuang Xu, Yuang Wei, 乔云晓, Xiaowen Song, Chuang Xie, Chunmei Zhou, Fuwen Yuan · 2026 · Cancer and Metastasis Reviews
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- Non-conventional histologies of prostate cancer: from morphology to biology-driven precision oncologyFabiano Flauto, Giuseppe Neola, Alessia Cimadamore, Michele Maffezzoli, Akash Maniam, Sarah Scagliarini, Fabio Calabrò, Luigi Formisano, Pasquale Rescigno, Giuseppe Luigi Banna · 2026 · The Oncologist
- tRNA dosage regulates lineage dependency and resistance in prostate cancerYeon Soo Kim, Sonali Arora, Dave Young, Ava Tsou, Amy Shiuan, Cynthia L. Wladyka, Dmytro Rudoy, Jin Yeong kim, Jennifer A. Waters, Samantha L. Schuster et al. · 2026 · Nature
- Targeting the HIF-1α–BSG metabolic circuit reverses enzalutamide resistance in prostate cancerXiuchen Guo, Jiacheng Huang, Zhiwei Chen, Haihong Liao, Yulin Xu, Yongjiang Yu · 2026 · Cellular Signalling
- Molecular features of prostate cancer with neuroendocrine differentiationBehtash Ghazi Nezami, Xiaoqi Lin · 2026 · Seminars in Diagnostic Pathology
- A Multi-Kinase Inhibitor Screen Identifies mTOR Signaling as a Vulnerability in Advanced Prostate CancerSriya Sridhar, Kabhilan Mohan, Smitha Kizhake, Amarnath Natarajan, David L Kelly, Grinu Mathew · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Lineage plasticity–driven immunometabolic state transitions in advanced prostate cancer: biomarkers and therapeutic stratificationHaowen Wu, Wei Zhang, Xin Yan, Kai Ma, Manuel Colucci, Qiang G Dong, Pan Song · 2026 · Seminars in Immunopathology
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