Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar +17 more·2018·Cancer Cell
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- KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53‐Mediated Tumor Suppressor PathwayArif Ul Hasan, Satoshi Serada, Sachiko Sato, Mami Obara, Sho Hirata, Yukako Nagase, Yukiko Kondo, Eiichi Taira · 2024 · Journal of Cellular Biochemistry
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- Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activityTaiichi Osumi, Taiki Nagano, Tetsushi Iwasaki, Jotaro Nakanishi, Kazuyuki Miyazawa, Shinji Kamada · 2025 · Scientific Reports
- CDC 7 inhibition drives an inflammatory response and a p53‐dependent senescent‐like state in breast epithelial cellsChiara Cazzaniga, Anja Göder, Michael David Rainey, Aisling Quinlan, Simone Coughlan, Stefanus Bernard, Corrado Santocanale · 2024 · FEBS Journal
- Detection of Gene Mutations in Liquid Biopsy of Melanoma Patients: Overview and Future PerspectivesNasr Alrabadi, Razan H. Haddad, Ahmed K. Alomari · 2020 · Current Treatment Options in Oncology
- The silent guardian: unraveling the roles of H3K9me3 in genome maintenanceZhiming Li, Zhiguo Zhang · 2024 · Genome Instability & Disease
- Molecular mechanisms and recent advances in cellular senescenceAshaq Hussain, Marc Tatar, Rujun Gong · 2026 · Cell & Bioscience
- Genetic and Epigenetic Influences on Cutaneous Cellular SenescenceTapash Jay Sarkar, Maiko Hermsmeier, Jessica L. Ross, G. Scott Herron · 2021 · Physiology
- UV light-induced dual promoter mutations dismantle the telomeric guardrails in melanomaSamantha L. Sanford, Patricia Lynn Opresko · 2022 · DNA repair
- Single-cell and spatial transcriptomics identify dihydrolipoic acid succinyltransferase as a promoter of tumor invasion via vascular pathways in cutaneous melanomaJinghua Gu, Xinyu Cheng, Jiansheng Xu, Huake Cao, Pei Liu, Zihao Wang, Pengcheng Wu, Xu Dong Zhang, Rick Francis Thorne, Hua Wang et al. · 2025 · International Journal of Biological Macromolecules
- Establishing a Novel Gene Signature Related to Histone Modifications for Predicting Prognosis in Lung AdenocarcinomaMengfeng Liu, Xiran Yu, Shidong Xu, Changfa Qu · 2022 · Journal of Oncology
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- To G0 or Not to G0: Cell Cycle Paradox in Senescence and Brain AgingShoma Ishikawa, Fuyuki Ishikawa · 2022 · Springer eBooks
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- Epigenetic ignition of melanomaLeslie K. Ferrarelli · 2018 · Science Signaling
- Arrested cells may awaken yetShraddha Chakradhar · 2019 · Nature Medicine
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- Evaluación de miRNAs en la línea celular de melanoma B16 inducida a pigmentación diferencial y disminución del crecimiento celular por la L-Tirosina y la 5-bromo-2´-deoxiuridinaRivera Escobar, Mauricio Hernán · 2020
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- Data from Metabolic Regulator IAPP (Amylin) Is Required for BRAF and RAS Oncogene-Induced SenescenceSam Garnett, Angeline de Bruyns, Veronique Provencher-Tom, Kendall Dutchak, Ran Shu, David L. Dankort · 2023
- Data from Metabolic Regulator IAPP (Amylin) Is Required for BRAF and RAS Oncogene-Induced SenescenceSam Garnett, Angeline de Bruyns, Veronique Provencher-Tom, Kendall Dutchak, Ran Shu, David L. Dankort · 2023
- Additional file 1 of KDM4C-mediated senescence defense is a targetable vulnerability in gastric cancer harboring TP53 mutationsKaiqing Wang, Zhicheng Gong, Yanyan Chen, Meimei Zhang, Suzeng Wang, Surui Yao, Zhihui Liu, Zhaohui Huang, Bojian Fei · 2023 · Figshare
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- Mapping the endothelial O-GlcNAcome uncovers CCAR1 as a regulator of senescenceAndreas Will, Regine Heller, Claudia Ender, Felix R. Schneidmadel, Florian Meier-Rosar, Darya Zibrova · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
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