Proteogenomic and metabolomic characterization of human glioblastoma

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Items 301–400 of 656

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3. SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation
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4. Mitochondrial Protein Density, Biomass, and Bioenergetics as Predictors for the Efficacy of Glioma Treatments
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5. MetaWise: Combined Feature Selection and Weighting Method to Link the Serum Metabolome to Treatment Response and Survival in Glioblastoma
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6. A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity
   Grant de Jong, Fani Memi, Tannia Gracia, Olga Lazareva, Oliver Gould, Georgios Solomou, Alexander Aivazidis, Manàs Dave, Qianqian Zhang, Melanie Jensen et al. · 2026 · Nature
7. A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
   Karunaraj, Prashath, Scheele, Remkes, Wells, Malcolm L., Rathod, Ruchita, Gokulu, Ipek S., Abrahamson, Sophia R., Taylor, Lila, Chowdhury, Lamia, Kazmi, Abiha, Song, Weixiao et al. · 2026 · Nature Communications
8. The SVZ stem cell niche–components, functions, and in vitro modelling
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9. Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma
   Catherine A. Behrmann, Kelli N. Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A. Clark, Kate M. Von Handorf, Subrahmanya Vallabhapurapu, Cristina Andreani, James K. Reigle, Pier Paolo Scaglioni et al. · 2024 · Cancer Research Communications
10. Brain tumour histopathology through the lens of deep learning: A systematic review
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11. Sonication-assisted protein extraction improves proteomic detection of membrane-bound and DNA-binding proteins from tumor tissues
    Qing Kay Li, T. Mamie Lih, David J. Clark, Lijun Chen, Michael Schnaubelt, Hui Zhang · 2025 · Nature Protocols
12. Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ubiquitylation of DDX6
    Emanuela Senatore, Rosario Avolio, Laura Rinaldi, Francesco Chiuso, Maria Antonietta Oliva, Chiara DˈAmbrosio, Antonio Giuseppe Bianco, Emiliano Dalla, Stefano Maria Pagnotta, Raffaella Flammia et al. · 2025 · EMBO Reports
13. Niche-specific epigenetic interventions in the spatially heterogeneous glioblastoma microenvironmental landscape: strategies for radiotherapy enhancement
    Junjie Wang, Kunjie Li, Yongzhe Wang, Junyi Zhang, Xin Peng, Ning Ji · 2025 · Frontiers in Molecular Biosciences
14. Neuroblastoma and Glioblastoma Cases With Amplified Oncogenes Have Reduced Numbers of Tumor-Resident Adaptive Immune Receptor Recombinations
    Toriana R. Dabkowski, Mallika Varkhedi, Joanna J. Song, Etienne C. Gozlan, George Blanck · 2023 · JCO Precision Oncology
15. MGMT ProFWise: Unlocking a New Application for Combined Feature Selection and the Rank-Based Weighting Method to Link MGMT Methylation Status to Serum Protein Expression in Patients with Glioblastoma
    Erdal Taşçı, Yajas Shah, Sarisha Jagasia, Ying Zhuge, Jason Shephard, Margaret O Johnson, Olivier Elemento, Thomas Joyce, Shreya Chappidi, Theresa Cooley Zgela et al. · 2024 · International Journal of Molecular Sciences
16. BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion
    Azadeh Ebrahimi, Andreas Waha, Jens Schittenhelm, Georg Gohla, Martin U. Schuhmann, Torsten Pietsch · 2024 · Acta Neuropathologica Communications
17. Automated Immunoprecipitation Workflow for Comprehensive Acetylome Analysis
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18. Mesenchymal-Type Genetic Mutations Are Likely Prerequisite for Glioblastoma Multiforme to Metastasize Outside the Central Nervous System: An Original Case Series and Systematic Review of the Literature
    Bryce J Laurin, Randall Treffy, Jennifer Connelly, Michael Wayne Straza, Wade M. Mueller, Max Ostrinsky Krucoff · 2024 · World Neurosurgery
19. Transcranial Magnetic Stimulation Enhances the Therapeutic Effect of IGF-Trap in Intracerebral Glioma Models
    Stéphanie Perrino, Udi Vazana, Ofer Prager, Lior Schori, Gal Ben‐Arie, Anna Minarik, Yinhsuan Michely Chen, Orçun Haçarız, Masakazu Hashimoto, Yiftach Roth et al. · 2024 · Pharmaceuticals
20. Bridging the gap between tumor and disease: Innovating cancer and glioma models
    Stéfano M. Cirigliano, Howard Alan Fine · 2024 · The Journal of Experimental Medicine
21. Holistic Analysis of Glioblastoma Stem Cell DNA Using Nanoengineered Plasmonic Metasensor for Glioblastoma Diagnosis
    Ashok Kumar Dhinakaran, Swarna Ganesh, Rupa Haldavnekar, Bo Tan, Sunit Das, Krishnan Venkatakrishnan · 2022 · Small Methods
22. The tumour ecology of quiescence: Niches across scales of complexity
    Simón P. Castillo, Felipe Gálvez‐Cancino, Jiali Liu, Steven M. Pollard, Sergio A. Quezada, Yinyin Yuan · 2023 · Seminars in Cancer Biology
23. Proteomics of tumor and serum samples from isocitrate dehydrogenase‐wildtype glioblastoma patients: is the detoxification of reactive oxygen species associated with shorter survival?
    Anne Clavreul, Catherine Guette, Hamza Lasla, Audrey Rousseau, Odile Blanchet, Cécile Henry, Alice Boissard, Mathilde Cherel, Pascal Jézéquel, François Guillonneau et al. · 2024 · Molecular Oncology
24. Expression and crucial role of long non-coding RNA FGD5-AS1 in human cancers.
    Lixu Zhu, Xiaoyi Shi, Xiao Yu, Zhihui Wang, Menggang Zhang, Yuting He, Wenzhi Guo · 2021 · PubMed Central
25. Predicting and Visualizing STK11 Mutation in Lung Adenocarcinoma Histopathology Slides Using Deep Learning
    Runyu Hong, Wenke Liu, David Fenyö · 2021 · BioMedInformatics
26. Blood proteomics for quantitative biomarkers of cellular therapies
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27. Toward the Best Generalizable Performance of Machine Learning in Modeling Omic and Clinical Data
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28. ACOX2 destabilizes the MRE11-RAD50-NBS1 complex and boosts anticancer immunity via the cGAS-STING pathway in clear cell renal cell carcinoma
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29. Machine learning model on multi-omics data enables risk stratification and identifies molecular heterogeneity and therapeutic targets in glioblastoma
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30. Plasminogen missense variants and their involvement in cardiovascular and inflammatory disease
    Teresa Brito-Robinson, Yetunde A. Ayinuola, Victoria A. Ploplis, Francis Castellino · 2024 · Frontiers in Cardiovascular Medicine
31. Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements
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32. Bulk and single-cell transcriptome revealed the metabolic heterogeneity in human glioma
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33. From Biomarker Discovery to Clinical Applications of Metabolomics in Glioblastoma
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34. GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma
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35. Long Non-coding RNA KTN1-AS1 Targets miR-505 to Promote Glioblastoma Progression
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36. Systems Medicine for Precise Targeting of Glioblastoma
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37. A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials
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38. PLK3 promotes the proneural–mesenchymal transition in glioblastoma via transcriptional regulation of C5AR1
    Shuo Yu, Lin Lv, Yang Li, Qian Ning, Tingting Liu, Tinghua Hu · 2023 · Molecular Biology Reports
39. Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma
    Daniel J. Picard, Jörg Felsberg, Maike Langini, Paweł Stachura, Nan Qin, Jadranka Macas, Yvonne Reiss, Jasmin Bartl, Florian Selt, Romain Sigaud et al. · 2023 · Acta Neuropathologica
40. Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy
    Xianlei Yan, Jinwei Li, Yang Zhang, Cong Liang, Pengcheng Liang, Tao Li, Quan Liu, Xuhui Hui · 2023 · Frontiers in Endocrinology
41. Lateralized overgrowth with vascular malformation caused by a somaticPTPN11pathogenic variant: Another piece added to the puzzle of mosaic RASopathies
    Alessandro Mussa, Antonella Turchiano, Simona Cardaropoli, Paola Coppo, Antonino Pantaleo, Rosanna Bagnulo, Carlotta Ranieri, Matteo Iacoviello, Antonella Garganese, Alessandro Stella et al. · 2022 · Genes Chromosomes and Cancer
42. Effectively utilizing publicly available databases for cancer target evaluation
    Daniel R. Croft, Puja Lodhia, Sofia Da Silva Lourenco, Craig MacKay · 2023 · NAR Cancer
43. Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup
    K. H. Brian Lam, Phedias Diamandis · 2022 · Scientific Data
44. Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex
    Raghavendra Vadla, Shunichiro Miki, Brett Taylor, Daisuke Kawauchi, Brandon M Jones, Nidhi Nathwani, Philip Pham, Jonathan Tsang, David A. Nathanson, Frank B. Furnari · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
45. Comprehensive biobanking strategy with clinical impact at the European Cancer Moonshot Lund Center
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46. Antibody reliability influences observed mRNA–protein correlations in tumour samples
    Swathi Ramachandra Upadhya, Colm J. Ryan · 2023 · Life Science Alliance
47. UHPLC-HRMS-based metabolomic and lipidomic characterization of glioma cells in response to anlotinib
    Yingying Shi, Zhuolun Li, Qiuzheng Du, Wenxi Li, Jiyun Liu, Qingquan Jia, Lianping Xue, Xiaojian Zhang, Zhi Sun · 2023 · Scientific Reports
48. Proteomic and metabolomic analyses illustrate the mechanisms of expression of the O 6 ‐methylguanine‐DNA methyltransferase gene in glioblastoma
    Xi Chen, Jinli Sun, Yukui Li, Weichao Jiang, Zhangyu Li, Jianyao Mao, Liwei Zhou, Sifang Chen, Guowei Tan · 2023 · CNS Neuroscience & Therapeutics
49. TP53 mutations and survival in patients with histologically defined Glioblastoma, IDH-wildtype
    Vincenzo Di Nunno, Lidia Gatto, Alicia Tosoni, Marta Aprile, Linda Galvani, Arianna Zappi, Maria Pia Foschini, Sofia Asioli, Giovanni Tallini, Dario de Biase et al. · 2024 · Pathology - Research and Practice
50. PTBP1-mediated repression of neuron-specific CDC42 splicing constitutes a genomic alteration-independent, developmentally conserved vulnerability in IDH-wildtype glioblastoma
    Junjie Yang, Jing Hai Feng, Jing Guo Lv, Xiaojing Chu, Yanfei Wei, Yunqiu Zhang, Jiuyi Li, Yingyu Sun, Guanzhang Li, Tao Jiang et al. · 2024 · Functional & Integrative Genomics
51. Status and Prospects of Glioblastoma Multiforme Treatments
    Xue Yang, Shibing Wang, Vedrana Montana, Xiangmin Tong, Vladimir Parpura · 2025 · Journal of Neurochemistry
52. AUTO-SP: Automated Sample Preparation for Analyzing Proteins and Protein Modifications
    T. Mamie Lih, Liyuan Jiao, Lijun Chen, Jongmin Jacob Woo, Yuefan Wang, Hui Zhang · 2025 · Analytical Chemistry
53. Glycoprotein-Notebook: A Pan-Cancer Glycoproteomic Database and Toolkit for Analysis of Protein Glycosylation Changes Associated With Cancer Phenotypes
    Hui Zhang, Trung Hoang, Yingwei Hu · 2025 · Molecular & Cellular Proteomics
54. Targeting super-enhancers reprograms glioblastoma central carbon metabolism
    Trang Thi Thu Nguyen, Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus David Siegelin · 2021 · Oncotarget
55. Metabolomics‐based classification reveals subtypes of hepatocellular carcinoma
    Guojun Hou, Dongyang Ding, Tian Tao, Wei Dong, Dapeng Sun, Gang Liu, Yuan Yang, Weiping Zhou · 2022 · Molecular Carcinogenesis
56. From Samples to Germline and Somatic Sequence Variation: A Focus on Next-Generation Sequencing in Melanoma Research
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57. Magnetic resonance imaging and deoxyribonucleic acid methylation–based radiogenomic models for survival risk stratification of glioblastoma
    Wentao Zhang, Zikang Yan, Jian Peng, Shan Zhao, Longke Ran, Haoyang Yin, Dong Zhong, Junjun Yang, Junyong Ye, Shengsheng Xu · 2023 · Medical & Biological Engineering & Computing
58. TENT5A Increases Glioma Malignancy and Promotes its Progression
    Jiali Hu, Lei Zeng, Rong-Huan Hu, Dan Gong, Mengmeng Liu, Jian-Wu Ding · 2024 · Recent Patents on Anti-Cancer Drug Discovery
59. EZH2 functional dichotomy in reactive oxygen species-stratified glioblastoma
    Lynnette Koh, Qing You Pang, Wisna Novera, See Wee Lim, Yuk Kien Chong, Jinyue Liu, Samantha Ya Lyn Ang, Ron Weng Yee Loh, Huilin Shao, Jianhong Ching et al. · 2024 · Neuro-Oncology
60. Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan
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61. A Calcium-Related Immune Signature in Prognosis Prediction of Patients With Glioma
    Cha Lin, Jian Chen, Zhaoying Su, Pei Liu, Zheyu Liu, Chenchen Zhu, Dan Xu, Zhongda Lin, Xu Pei, Ganqiang Liu et al. · 2021 · Frontiers in Cell and Developmental Biology
62. Glioblastoma stem cells express non‐canonical proteins and exclusive mesenchymal‐like or non‐mesenchymal‐like protein signatures
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63. Natural killer cells in the treatment of glioblastoma: Diverse antitumor functions and potential clinical applications
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64. Proteogenomics 101: a primer on database search strategies
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65. Complementary Nuclear Magnetic Resonance-Based Metabolomics Approaches for Glioma Biomarker Identification in a Drosophila melanogaster Model
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66. A Toolkit for Profiling the Immune Landscape of Pediatric Central Nervous System Malignancies
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67. mosaicMPI: a framework for modular data integration across cohorts and -omics modalities
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68. Trends in the immunotherapy for glioblastoma: A two-decade bibliometric analysis
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69. Synthesis of selective BCL-XL PROTAC and potent antitumor activity in glioblastoma
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70. Glioportal: a comprehensive transcriptomic resource unveiling ligand-mediated mesenchymal transition in glioblastoma
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71. Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
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72. Meta-analysis of multi-center transcriptomic profiles and machine learning reveal phospholipase Cβ4 as a Wnt/Ca²+ signaling mediator in glioblastoma immunotherapy
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73. Genomic landscape and immunological profile of glioblastoma in East Asian patients
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74. Integrated pathway analysis identifies prognostically relevant subtypes of glioblastoma characterized by abnormalities in multi‐omics
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75. Data-Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research.
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76. A data-driven pan-cancer proteogenomic analysis reveals the characteristics of human cancer protein expression
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77. GlioMODA: Robust glioma segmentation in clinical routine
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78. Exploiting metabolic dependencies for therapeutic targeting of brain cancers
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79. Glioblastoma and PARP inhibitors: the importance of patient selection to maximize therapeutic benefits. A critical review
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80. Advances in plasma metabolomics detection technology and its clinical applications in lung cancer and other malignancies
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81. From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity
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82. Glioma Stem Cells Are Sensitized to BCL-2 Family Inhibition by Compromising Histone Deacetylases
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83. Liquid chromatography coupled to mass spectrometry metabolomic analysis of cerebrospinal fluid revealed the metabolic characteristics of moyamoya disease
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84. KinPred-RNA—kinase activity inference and cancer type classification using machine learning on RNA-seq data
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85. Proteomic-based stemness score measures oncogenic dedifferentiation and enables the identification of druggable targets
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86. Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM
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87. Identification of Potential Biomarkers of Platelet RNA in Glioblastoma by Bioinformatics Analysis
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88. Metabolic Modeling Identifies a Novel Molecular Type of Glioblastoma Associated with Good Prognosis
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89. Quantitative Assessment of Preanalytic Variables on Clinical Evaluation of PI3/AKT/mTOR Signaling Activity in Diffuse Glioma
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90. Methodological Approaches for Assessing Metabolomic Changes in Glioblastomas
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91. The underlying molecular mechanisms and biomarkers of plaque vulnerability based on bioinformatics analysis
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92. Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high‐grade gliomas
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93. Radiomic Consensus Clustering in Glioblastoma and Association with Gene Expression Profiles
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94. Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients
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95. Amyloid precursor protein accumulation in glioblastoma is associated with altered synaptic dynamics and immune suppression
    Tyrel R. Porter, Mikhail Y. Inyushin, Lilia Y. Kucheryavykh · 2025 · Discover Oncology
96. Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
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97. DSCC: disease subtyping using spectral clustering and community detection from consensus networks
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98. INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model
    Patrick DeSouza, Matthew Ishahak, Xuan Qu, Colin R. McCornack, Devi Annamalai, Diane D. Mao, Rajanikanth Vangipurapu, Yiwei Fu, Alexandre Teixeira Vessoni, Ryan T. Cleary et al. · 2025 · Nature Communications
99. A prognostic matrix gene expression signature defines functional glioblastoma phenotypes and niches
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100. The functional imperative in high-grade glioma
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