Development and Implementation of Sepsis Alert Systems
Open accessAbstract
Development and implementation of sepsis alert systems is challenging, particularly outside the monitored intensive care unit (ICU) setting. Barriers to wider use of sepsis alerts include evolving clinical definitions of sepsis, information overload, and alert fatigue, due to suboptimal alert performance. Outside the ICU, barriers include differences in health care delivery models, charting behaviors, and availability of electronic data. Current evidence does not support routine use of sepsis alert systems in clinical practice. Continuous improvement in the afferent and efferent aspects will help translate theoretic advantages into measurable patient benefit.
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Many sepsis CDS systems fail to improve outcomes because of poor diagnostic accuracy and program implementation.
“Unfortunately, many sepsis CDS systems fail to improve outcomes because of poor diagnostic accuracy and program implementation [23-25].”
From Integrating a Machine Learning System Into Clinical Workflows: Qualitative Study (2020) · cites this paper as [24]
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Self-citation
- Authors
- Harrison, A. M., Gajic, O., Pickering, B. W., & Herasevich, V.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Herasevich, Vitaly
- Venue
- Clinics in Chest Medicine
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 37
- Issue
- 2
- Pages
- 219-229
- ISSN
- 0272-5231 (ISSN-L)
- PMC
- PMC4884325
- OpenAlex
- W2330656570
- Cited by
- 46
- References
- 1
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 1
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Clinics in Chest Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Agency for Healthcare Research and Quality (R36HS022799)
- National Heart, Lung, and Blood Institute (UH3HL125119, UH2HL125119, U01HL121819)
- Topics
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Healthcare Technology and Patient Monitoring
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Keywords
- sepsis, alarm fatigue, clinical decision support, electronic health records, non-ICU settings, sepsis definitions, information overload, implementation barriers, models of care
- MeSH terms
- Humans, Intensive Care Units, Sepsis
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