A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

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Items 101–200 of 239

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4. A Potential Role for Integrin-Linked Kinase in Colorectal Cancer Growth and Progression via Regulating Senescence and Immunity
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8. Relationship between Obesity, Gut Microbiome and Hepatocellular Carcinoma Development
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9. The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP)
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10. Hepatocellular carcinoma repression by TNFα‐mediated synergistic lethal effect of mitosis defect‐induced senescence and cell death sensitization
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11. Recent Synthetic Approaches towards Small Molecule Reactivators of p53
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12. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
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13. Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging‐associated tumorigenesis induced by ultraviolet B
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14. Integration of chemokine signaling with non-coding RNAs in tumor microenvironment and heterogeneity in different cancers
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15. Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
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16. Impact of cancer cell-intrinsic features on neutrophil behavior
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17. Revisiting Epithelial Carcinogenesis
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18. EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells
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19. Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models
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20. CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis
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21. Know your enemy: Genetics, aging, exposomic and inflammation in the war against triple negative breast cancer
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22. Establishment of a Macrophage Phenotypic Switch Related Prognostic Signature in Patients With Pancreatic Cancer
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23. A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches
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24. It takes a village: microbiota, parainflammation, paligenosis and bystander effects in colorectal cancer initiation
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25. Does Inflammation Contribute to Cancer Incidence and Mortality during Aging? A Conceptual Review
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26. Immune and inflammation: related factor alterations as biomarkers for predicting prognosis and responsiveness to PD-1 monoclonal antibodies in cervical cancer
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27. Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer
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28. The Potential of Targeting P53 and HSP90 Overcoming Acquired MAPKi-Resistant Melanoma
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29. The Trinity of Matrix Metalloproteinases, Inflammation, and Cancer: A Literature Review of Recent Updates
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30. The impact of the senescent microenvironment on tumorigenesis: Insights for cancer therapy
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31. Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells
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32. MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan
    Mingfu Tian, Yuqing Huang, Yunting Song, Wen Li, Peiyi Zhao, Weiyong Liu, Kailang Wu, Jianguo Wu · 2020 · Advanced Science
33. Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?
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34. Metabolic reprogramming links chronic intestinal inflammation and the oncogenic transformation in colorectal tumorigenesis
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35. Cellular plasticity and metastasis in breast cancer: a pre- and post-malignant problem
    Jacob M. Smigiel, Sarah E. Taylor, Benjamin L. Bryson, Ilaria Tamagno, Kelsey L. Polak, Mark W. Jackson · 2019 · Journal of Cancer Metastasis and Treatment
36. Stress-induced cellular senescence contributes to chronic inflammation and cancer progression.
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37. Genes and pathways involved in senescence bypass identified by functional genetic screens
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38. Senescence-Associated Molecules and Tumor-Immune-Interactions as Prognostic Biomarkers in Colorectal Cancer
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39. Oral fullerene tablets for colorectal cancer therapy based on modulation of tumor inflammatory microenvironments
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40. TUBB4B is a novel therapeutic target in non‐alcoholic fatty liver disease‐associated hepatocellular carcinoma
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41. The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis
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42. The Genetic Architecture of Murine Glutathione Transferases
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43. The Regulation of Cellular Senescence in Cancer
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44. Doxorubicin-Induced Cardiotoxicity May Be Alleviated by Bone Marrow Mesenchymal Stem Cell-Derived Exosomal lncRNA via Inhibiting Inflammation
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45. Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma
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46. Cancer Cell–Autonomous Parainflammation Mimics Immune Cell Infiltration
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47. Preoperative C-reactive protein-to-albumin ratio and clinical outcomes after resection of colorectal liver metastases
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48. DNA damage in protective and adverse inflammatory responses: Friend of foe?
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49. Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia
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50. A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
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51. Adult Stem Cells and Anticancer Therapy
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52. Expression of Allograft Inflammatory Factor-1 (AIF-1) in Hepatocellular Carcinoma
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53. A three-layer perspective on miRNA regulation in β cell inflammation
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54. Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis
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55. Developing senescence to remodel the embryo
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56. Therapy-Induced Senescence (TIS) and SASP: The p53-Mediated Interplay in Cancer Progression and Treatment
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57. Intracellular signaling modules linking DNA damage to secretome changes in senescent melanoma cells
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58. ANGPTL4-the Link Binding Lipid Metabolism and Inflammation
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59. The Role of Serine Peptidase Inhibitor Kazal Type 13 (SPINK13) as a Clinicopathological and Prognostic Biomarker in Patients with Clear Cell Renal Cell Carcinoma
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60. Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia
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61. Senescent cells and macrophages cooperate through a multi-kinase signaling network to promote intestinal transformation in Drosophila
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62. Injectable Senolytic Hydrogel Depot for the Clearance of Senescent Cells
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63. Tumor-derived CK1α mutations enhance MDMX inhibition of p53
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72. Cellular Senescence: a Promising Therapeutic Target in Colorectal Cancer
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74. Cellular Carcinogenesis: Role of Polarized Macrophages in Cancer Initiation
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75. A Senescence-Mimicking (Senomimetic) VEGFR TKI Side Effect Primes Tumor Immune Responses via IFN/STING Signaling
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77. The Interplay of Aging and Cancer: Mechanisms, Implications, and Therapeutic Strategies
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78. Collecting the evidence: mechanistic insights into Akkermansia muciniphila’s impact on aging and systemic inflammation
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79. Tissue-Predisposition to Cancer Driver Mutations
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80. NFATc1 facilitates hepatocellular carcinoma progression by regulating the senescence-associated secretory phenotype
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82. Controlling secretion to limit chemoresistance
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84. Tumor-Independent Host Secretomes Induced By Angiogenesis and Immune-Checkpoint Inhibitors
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86. Cellular senescence and liver cancer: a gut microbial connection
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87. Inflammatory response in gastrointestinal cancers: Overview of six transmembrane epithelial antigens of the prostate in pathophysiology and clinical implications
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90. Unraveling senescence in cancer: mechanistic complexities and therapeutic opportunities
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93. Cellular senescence and chronic inflammation
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95. Tumor Promoting Aspects of Senescence in Cancer Progression
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96. Cellular Senescence and Tumor Promotion
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98. Cellular Senescence
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99. Cellular Senescence
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100. Cellular senescence: from pathogenic mechanisms to precision anti-aging interventions
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