ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics

Arteaga, Carlos L., Engelman, Jeffrey A.·2014·Cancer Cell

DOI 10.1016/j.ccr.2014.02.025

Cited by (999)

Items 401–500 of 999

Pockets as structural descriptors of EGFR kinase conformations
Marcia Anahí Hasenahuer, German Patricio Barletta, Sebastian Fernández-Alberti, Gustavo D. Parisi, Marı́a Silvina Fornasari · 2017 · PLoS ONE
A Text-Based Computational Framework for Patient-Specific Modeling for Classification of Cancers
Hiroaki Imoto, Sawa Yamashiro, Mariko Okada · 2021 · iScience
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC
Shiyu Li, Shuangli Zhu, Hongqu Wei, Pengfei Zhu, Ying Jiao, Ming Yi, Juejun Gong, Kun Zheng, Li Zhang · 2022 · Biomedicine & Pharmacotherapy
Synergistic therapeutic potential of alpelisib in cancers (excluding breast cancer): Preclinical and clinical evidences
Yuhao Ye, Zhiyu Huang, Maoqing Zhang, Jiayue Li, Yiqiong Zhang, Chenghua Lou · 2023 · Biomedicine & Pharmacotherapy
Mutation analysis of the EGFR pathway genes, EGFR, RAS, PIK3CA, BRAF, and AKT1 , in salivary gland adenoid cystic carcinoma
Kosuke Saida, Takayuki Murase, Mayuko Ito, Kana Fujii, Hisashi Takino, Ayako Masaki, Daisuke Kawakita, Kei Ijichi, Yuichiro Tada, Kimihide Kusafuka et al. · 2018 · Oncotarget
Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples
Bizhu Chu, An He, Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Ruilian Xu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang et al. · 2018 · Proceedings of the National Academy of Sciences
Targeting tumor cells with antibodies enhances anti-tumor immunity
Zhichen Sun, Yang‐Xin Fu, Hua Peng · 2018 · Biophysics Reports
Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology
Anne M. Lynch, Brandie D. Wagner, Sophie J. Weiss, Kirsten M. Wall, Alan Gary Palestine, Marc T. Mathias, Frank S. Siringo, Jennifer N. Cathcart, Jennifer L. Patnaik, Daniel W. Drolet et al. · 2019 · Translational Vision Science & Technology
Phytochemical Loaded Nanovehicles of Biopolymer for Breast Cancer: A Systemic Review
Vivek P. Chavda, Suneetha Vuppu, Rajashri Bezbaruah, Lakshmi Vineela Nalla, Siva Nageswara Rao Gajula, Pankti C. Balar, Toshika Mishra, Nikita Sharma, Sathvika Kamaraj, Thushar Suresh et al. · 2023 · Clinical Complementary Medicine and Pharmacology
Near infrared imaging of epidermal growth factor receptor positive xenografts in mice with domain I/II specific antibody fragments
Wendy Bernhard, Ayman El‐Sayed, Kris Barreto, Carolina Gonzalez, Humphrey Fonge, Clarence Ronald Geyer · 2019 · Theranostics
The catalytically defective receptor protein tyrosine kinase EphA10 promotes tumorigenesis in pancreatic cancer cells
Won‐Sik Shin, Mi Kyung Park, Young Hun Lee, Kyungwoo Kim, Ho Lee, Seung‐Taek Lee · 2020 · Cancer Science
Excessive All-Trans Retinoic Acid Inhibits Cell Proliferation Through Upregulated MicroRNA-4680-3p in Cultured Human Palate Cells
Hiroki Yoshioka, Sai Shankar Ramakrishnan, Junbo Shim, Akiko Suzuki, Junichi Iwata · 2021 · Frontiers in Cell and Developmental Biology
Induction of EnR stress by Melatonin enhances the cytotoxic effect of Lapatinib in HER2-positive breast cancer
Xiaolin Sang, Li Li, Chunhua Rui, Yichao Liu, Zundong Liu, Zhiwei Tao, Hai-Ling Margaret Cheng, Pixu Liu · 2021 · Cancer Letters
Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies
Juan José Mata, Joseba Rebollo-Liceaga, E. Martinez-Navarro, Ramón González Manzano, Antonio Brugarolas, Manel Juan, Manuel Sureda · 2022 · Frontiers in Oncology
Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
Raphael Trenker, Devan C. Diwanji, Tanner Bingham, Kliment A. Verba, Natalia Jura · 2023 · eLife
Exploring diorganotin(IV) complexes of hydrazone based ligands as multi-target agents: Synthesis, structural characterization, DFT and in vitro biological evaluation
Naresh Kumar, Sonika Asija, Yogesh Deswal, Jagat Singh Kirar, Deepak Kumar, Deepak Kumar Jindal, Biswarup Basu, Monu Kumar Shukla · 2024 · Inorganic Chemistry Communications
Insights into next developments in advanced gastric cancer
Radka Lordick Obermannova, Florian Lordick · 2016 · Current Opinion in Oncology
Cardiotoxicity of ErbB2-targeted therapies and its impact on drug development, a spotlight on trastuzumab
Milos Dokmanovic, Kathryn E. King, Nishant Mohan, Yukinori Endo, Wen Jin Wu · 2017 · Expert Opinion on Drug Metabolism & Toxicology
Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer
Adam J. Camblin, Gege Tan, Michael D. Curley, Isabel Yannatos, Sergio Iadevaia, Victoria M. Rimkunas, Mari A. Mino-Kenudson, Troy Bloom, Birgit Schoeberl, Daryl C. Drummond et al. · 2019 · Scientific Reports
MicroRNAs involved in the EGFR pathway in glioblastoma
Bin Xu, Jie Mei, Wei Ji, Zhengyuan Huo, Zheng Bian, Jiantong Jiao, Xiaoqing Li, Jun Sun, Junfei Shao · 2020 · Biomedicine & Pharmacotherapy
Recent advancement in targeted therapy and role of emerging technologies to treat cancer
Shrikant Barot, Henis J. Patel, Anjali Yadav, Igor Ban · 2023 · Medical Oncology
DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
Majid Momeny, Mari Tienhaara, Mukund Sharma, Deepankar Chakroborty, Roosa Varjus, Iina Takala, Joni Merisaari, Artur Padzik, Andreas Vogt, Ilkka Paatero et al. · 2024 · EMBO Molecular Medicine
Emerging role of chemoprotective agents in the dynamic shaping of plasma membrane organization
Natividad Roberto Fuentes, Michael L. Salinas, Eunjoo Kim, Robert S. Chapkin · 2017 · Biochimica et Biophysica Acta (BBA) - Biomembranes
Annexin A6 improves anti‐migratory and anti‐invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells
Monira Hoque, Yasmin A. Elmaghrabi, Meryem Köse, Syed Sultan Beevi, Jaimy Jose, Elsa Meneses‐Salas, Patricia Blanco‐Muñoz, James R. W. Conway, Alexander Swarbrick, Paul Timpson et al. · 2019 · FEBS Journal
Circular RNA circEMB promotes osteosarcoma progression and metastasis by sponging miR-3184-5p and regulating EGFR expression
Jianye Tan, Bingsheng Yang, Haobo Zhong, Mengliang Luo, Zexin Su, Chao Lian Xie, Meiling Shi, Chunhan Sun, Lijun Lin · 2023 · Biomarker Research
Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations
Syuzo Kaneko, Ken Takasawa, Ken Asada, Kouya Shiraishi, Noriko Ikawa, Hidenori Machino, Norio Shinkai, Maiko Matsuda, Mari Masuda, Shungo Adachi et al. · 2024 · Molecular Cancer
Personalized treatment for colorectal cancer: novel developments and putative therapeutic strategies
Jamil Akkad, Sylvia Bochum, Uwe M. Martens · 2015 · Langenbeck s Archives of Surgery
Modular Nanotransporters for Targeted Intracellular Delivery of Drugs: Folate Receptors as Potential Targets
Tatiana A. Slastnikova, Andrey A. Rosenkranz, Michael R. Zalutsky, Alexander S. Sobolev · 2014 · Current Pharmaceutical Design
Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance
Sally Naji Temraz, Deborah Mukherji, Ali I. Shamseddine · 2016 · Critical Reviews in Oncology/Hematology
Discovery of ERBB3 inhibitors for non-small cell lung cancer (NSCLC) via virtual screening
Rong Guo, Yuan Zhang, Xiao Li, Xinrui Song, Da Li, Yong Zhao · 2016 · Journal of Molecular Modeling
89Zr-mAb3481 PET for HER3 tumor status assessment during lapatinib treatment
Martin Pool, Arjan Kol, Steven de Jong, Elisabeth G.E. de Vries, Marjolijn N. Lub–de Hooge, Anton G.T. Terwisscha van Scheltinga · 2017 · mAbs
Small-molecule-induced ERBB4 activation to treat heart failure
Julie M. T. Cools, Bo Goovaerts, Eline Feyen, Siel Van den Bogaert, Yile Fu, Céline Civati, Jens Van fraeyenhove, Michiel R. L. Tubeeckx, Jasper Ott, Long Nguyen et al. · 2025 · Nature Communications
HER2 and HER3 as Therapeutic Targets in Head and Neck Cancer
Robert Saddawi‐Konefka, Shiruyeh Schokrpur, Asona J. Lui, Jorge Silvio Gutkind · 2022 · The Cancer Journal
ERBB Signaling Pathway in Cancer Stem Cells
Ghmkin Hassan, Masaharu Seno · 2022 · Advances in experimental medicine and biology
Circular RNAs with protein-coding ability in oncogenesis
Jiahui Cheng, Guangyue Li, Wenmeng Wang, Daniel B. Stovall, Guangchao Sui, Dangdang Li · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Landscape of Genetic Mutations in Appendiceal Cancers
Marian Constantin, Cristina Mătanie, Livia Petrescu, Alexandra Bolocan, Octavian Andronic, Coralia Bleoţu, Mihaela Magdalena Mitache, Sorin Ioan Tudorache, Corneliu Ovidiu Vrâncianu · 2023 · Cancers
Systematic Identification of Oncogenic EGFR Interaction Partners
Julia Petschnigg, Max Kotlyar, Louise Blair, Igor Jurišica, Igor Štagljar, Robin Ketteler · 2016 · Journal of Molecular Biology
Tumour‐associated changes in intestinal epithelial cells cause local accumulation of KLRG 1+ GATA 3+ regulatory T cells in mice
Holger Meinicke, Anna Bremser, Maria Brack, Paulina Akéus, Claire F. Pearson, Samuel J. Bullers, Katrin Hoffmeyer, Marc P. Stemmler, Marianne Quiding‐Järbrink, Ana Ízcue · 2017 · Immunology
Breast cancer dissemination promoted by a neuregulin-collagenase 3 signalling node
Samuel Seoane, Juan Carlos Montero, Alberto Ocaña, Atanasio Pandiella · 2015 · Oncogene
Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines
Katarzyna Jastrzebski, Bram Thijssen, Roelof J.C. Kluin, Klaas de Lint, Ian J. Majewski, Roderick L. Beijersbergen, Lodewyk F.A. Wessels · 2018 · Cancer Research
Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer
Zhipeng Li, Jipei Liao, Zejia Yang, Eun Yong Choi, Rena G. Lapidus, Xuefeng Liu, Kevin J. Cullen, Hancai Dan · 2018 · British Journal of Cancer
The expression and prognostic value of the epidermal growth factor receptor family in glioma
Bin Xu, Zhengyuan Huo, Hui Huang, Wei Ji, Zheng Bian, Jiantong Jiao, Jun Sun, Junfei Shao · 2021 · BMC Cancer
Growth Hormone Modulation of Hepatic Epidermal Growth Factor Receptor Signaling
Lorena González, María Eugenia Díaz, Johanna Gabriela Miquet, Ana I. Sotelo, Fernando Pablo Dominici · 2021 · Trends in Endocrinology and Metabolism
Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer
Luis D. Borrero-García, María del Mar Maldonado, Julia Medina‐Velázquez, Angel Luis Troche‐Torres, Luis Velazquez, Nilmary Grafals‐Ruiz, Suranganie Dharmawardhane · 2021 · BMC Cancer
Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance
Xinlei Zhuang, Zhe Wang, Jiansheng Fan, Xuefei Bai, Yingchun Xu, James Jeiwen Chou, Tingjun Hou, Shuqing Chen, Liqiang Pan · 2022 · Nature Communications
Cellular and molecular features related to exceptional therapy response and extreme long‐term survival in glioblastoma
Brecht Decraene, Maxime Vanmechelen, Paul M. Clément, Jean‐François Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Dinkarnath Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer · 2023 · Cancer Medicine
Natural products as drug candidates for breast cancer (Review)
NITIN T. TELANG · 2023 · Oncology Letters
Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform
Josef Singer, Krisztina Manzano-Szalai, Judit Fazekas, Kathrin Thell, Anna Lukschal, Caroline Stremnitzer, Franziska Roth‐Walter, Margit Weghofer, Mirko Ritter, Kerstin Pino Tossi et al. · 2016 · OncoImmunology
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion
Ditte Marie Brix, Siri Amanda Tvingsholm, Malene Bredahl Hansen, Knut Kristoffer Bundgaard Clemmensen, Tiina Öhman, Valentina Siino, Matteo Lambrughi, Klaus H. Hansen, Pietri Puustinen, Irina Gromova et al. · 2019 · Oncogene
Slight advantages of nimotuzumab versus cetuximab plus concurrent chemoradiotherapy in locally advanced esophageal squamous cell carcinoma
Jing Wang, Weiwei Yan, Yuguo Liu, Ji Li, Jinming Yu, Hui Zhu · 2019 · Cancer Biology & Therapy
Aminated laminaran from brown alga Saccharina cichorioides: Synthesis, structure, anticancer, and radiosensitizing potential in vitro
Olesya S. Malyarenko, Roza V. Usoltseva, Artem S. Silchenko, Svetlana Pavlovna Ermakova · 2020 · Carbohydrate Polymers
NCOA3 is a critical oncogene in thyroid cancer via the modulation of major signaling pathways
Yujun Li, Junrong Liang, Hui Dang, Rui Zhang, Pu Chen, Yuan Shao · 2021 · Endocrine
Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1
Vehary A. Sakanyan, Philippe Hulin, Rodolphe Alves de Sousa, Viviane Aline Oliveira Silva, Artur A. Hambardzumyan, Steven Nédellec, Christophe Tomasoni, Cédric Logé, Charles Pineau, Christos Roussakis et al. · 2016 · Scientific Reports
DHA Affects Microtubule Dynamics Through Reduction of Phospho-TCTP Levels and Enhances the Antiproliferative Effect of T-DM1 in Trastuzumab-Resistant HER2-Positive Breast Cancer Cell Lines
Silvia D’Amico, Ewa Krystyna Krasnowska, Isabella Manni, Gabriele Toietta, Silvia Baldari, Giulia Piaggio, Marco Ranalli, Alessandra Gambacurta, Claudio Vernieri, Flavio Di Giacinto et al. · 2020 · Cells
Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex
Gerarduzzi, Casimiro, de Polo, Anna, Liu, Xue-Song, El Kharbili, Manale, Little, John B., Yuan, Zhi-Min · 2016 · Journal of Biological Chemistry
Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma
Lièvre, Astrid, Ouine, Bérèngere, Canet, Jim, Cartier, Aurélie, Amar, Yael, Cacheux, Wulfran, Mariani, Odette, Guimbaud, Rosine, Selves, Janick, Lecomte, Thierry et al. · 2017 · British Journal of Cancer
Advances in Nanobody-Based Platforms for Precision Cancer Diagnosis and Therapy
Yang Yuan, Ciren Zhuoga, Chen Zeng, Wenya Zhou, Weizhi Chen, Zhen Cheng Xu, Xiqun Jiang · 2025 · Polymer science & technology.
Mechanisms of resistance to antibody-drug conjugates in breast cancer
Barış Çerçi, Özge Saatci, Mark Basik, Özgür Şahin · 2026 · Drug Resistance Updates
LncRNA PCAT7 Promotes the Malignant Progression of Breast Cancer by Regulating ErbB/PI3K/Akt Pathway
Jiao-qun Zhou, Shiwei Zhang, Mingyuan Luo · 2021 · Future Oncology
PKCδ-mediated SGLT1 upregulation confers the acquired resistance of NSCLC to EGFR TKIs
Chia‐Hung Chen, Bo‐Wei Wang, Yu-Chun Hsiao, Chun-Yi Wu, Fang‐Ju Cheng, Te‐Chun Hsia, Chih‐Yi Chen, Yihua Wang, Zhang Weihua, Ruey‐Hwang Chou et al. · 2021 · Oncogene
Targeting Gi/o protein–coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy
Cancan Lyu, Yuanchao Ye, Maddison Lensing, Kay‐Uwe Wagner, Ronald J. Weigel, Songhai Chen · 2021 · JCI Insight
Crosstalk between the B7/CD28 and EGFR pathways: Mechanisms and therapeutic opportunities
Xiaoxin Ren, Yixian Li, Christopher Nishimura, Xingxing Zang · 2021 · Genes & Diseases
From Anti-HER-2 to Anti-HER-2-CAR-T Cells: An Evolutionary Immunotherapy Approach for Gastric Cancer
Jiangang Sun, Xiaojing Li, Peng Chen, Yongshun Gao · 2022 · Journal of Inflammation Research
Acacetin exerts antitumor effects on gastric cancer by targeting EGFR
Guangtao Zhang, Jiahuan Dong, Lu Lu, Yujing Liu, Dan Hu, Yuanmin Wu, Aiguang Zhao, Hanchen Xu · 2023 · Frontiers in Pharmacology
Immunotherapy in colorectal cancer: Statuses and strategies
Yuan Li, Zewei Cheng, Shengli Li, Jiwei Zhang · 2024 · Heliyon
Design, synthesis, and evaluation of cisplatin-containing EGFR targeting bioconjugates as potential therapeutic agents for brain tumors
Rolf F. Barth, Gong Jhe Wu, Walter Hans Meisen, Robin J. Nakkula, Weilian Yang, Tianyao Huo, David A. Kellough, Pravin T. P. Kaumaya, Lawrence M Agius, Balveen Kaur et al. · 2016 · OncoTargets and Therapy
Established, emerging and elusive molecular targets in the treatment of lung cancer
Jean‐Nicolas Gallant, Christine Marie Lovly · 2018 · The Journal of Pathology
Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition
Erik Klapproth, Ellen Dickreuter, Falk Zakrzewski, Michael Seifert, Andreas Petzold, Andreas Dahl, Evelin Schröck, Barbara Klink, Nils Cordes · 2018 · Oncotarget
Clinical Impact of Rare and Compound Mutations of Epidermal Growth Factor Receptor in Patients With Non–Small-Cell Lung Cancer
Juliane Martin, Annika Lehmann, Frederick Klauschen, Michael Hummel, Dido Lenze, Christian Grohé, Antje Tessmer, Joachim Gottschalk, Berndt Schmidt, H. W. Pau et al. · 2019 · Clinical Lung Cancer
ErbB receptors and tetraspanins: Casting the net wider
Fedor Berditchevski, Elena Odintsova · 2016 · The International Journal of Biochemistry & Cell Biology
Combination Strategies with HSP90 Inhibitors in Cancer Therapy: Mechanisms, Challenges, and Future Perspectives
Yeongbeom Kim, Su Yeon Lim, Hyun‐Ouk Kim, Suk‐Jin Ha, Jeong‐Ann Park, Young‐Wook Won, Sehyun Chae, Kwang Suk Lim · 2025 · Pharmaceuticals
Pharmacophore modeling, virtual screening, molecular docking and dynamics studies for the discovery of HER2-tyrosine kinase inhibitors: An in-silico approach
Gurubasavaraja Swamy Purawarga Matada, Prasad Sanjay Dhiwar, Nahid Abbas, Ekta Singh, Abhishek Ghara, Rajesh B. Patil, Nulgumnalli Manjunathaiah Raghavendra · 2022 · Journal of Molecular Structure
Direct Observation of Endocytosis Dynamics of Anti-ErbB Modified Single Nanocargoes
Feng Ge, Yi Du, Yan He · 2022 · ACS Nano
[Retracted] CD73 (NT5E) Promotes the Proliferation and Metastasis of Lung Adenocarcinoma through the EGFR/AKT/mTOR Pathway
Hong Zhang, Yu Cao, Jianming Tang, Rui Wang · 2022 · BioMed Research International · Retracted
Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2 + breast cancer by ceramide-loaded nanoparticles
Sandeep Kumar, Subhasis Das, Jingjing Sun, Yixian Huang, Sunil Kumar Singh, Piush Srivastava, Gautam V. Sondarva, Rakesh Sathish Nair, Navin Viswakarma, Balaji B. Ganesh et al. · 2022 · Proceedings of the National Academy of Sciences
Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing
Adele Alagia, Jana Tereňová, Ruth F. Ketley, Arianna Di Fazio, Irina Chelysheva, Monika Gullerová · 2023 · Life Science Alliance
Folic Acid-Modified Ibrutinib-Loaded Silk Fibroin Nanoparticles for Cancer Cell Therapy with Over-Expressed Folate Receptor
Marta G. Fuster, Mercedes G. Montalbán, Imane Moulefera, Gloria Víllora, David Lee Kaplan · 2023 · Pharmaceutics
Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells
Limei Xu, Feifei Shi, Yingdi Wu, Shun Yao, Yingying Wang, Xukai Jiang, Ling Su, Xiangguo Liu · 2023 · Cell Communication and Signaling
Afatinib-Based Combination Regimens for the Treatment of Solid Tumors: Rationale, Emerging Strategies and Recent Progress
Jaafar Bennouna, Shanti Ricardo Moreno Vera · 2015 · Future Oncology
Complete and Durable Remission of Human Epidermal Growth Factor Receptor 2-Positive Metastatic Urothelial Carcinoma Following Third-Line Treatment with Trastuzumab and Gemcitabine
Felix Wezel, Philipp Erben, Timo Gaiser, Johannes Budjan, Jost von Hardenberg, Maurice Stephan Michel, Christian Bolenz · 2016 · Urologia Internationalis
Monitoring Trastuzumab Resistance and Cardiotoxicity
Milos Dokmanovic, Wen Jin Wu · 2015 · Advances in clinical chemistry
The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3
Jason Hatakeyama, Jessica H. Wald, Hanine Rafidi, Antonio Cuevas-Navarro, Colleen A. Sweeney, Kermit L. Carraway · 2016 · Science Signaling
Photon‐Induced Near‐Field Electron Microscopy of Eukaryotic Cells
Mohammed Kaplan, Byung‐Kuk Yoo, Jau Tang, Tony E. Karam, Bolin Liao, Devdoot S. Majumdar, David Baltimore, Grant J. Jensen, Ahmed H. Zewail · 2017 · Angewandte Chemie International Edition
HER2 in stemness and epithelial–mesenchymal plasticity of breast cancer
Ioannis A. Voutsadakis · 2018 · Clinical & Translational Oncology
How Different Substitution Positions of F, Cl Atoms in Benzene Ring of 5-Methylpyrimidine Pyridine Derivatives Affect the Inhibition Ability of EGFRL858R/T790M/C797S Inhibitors: A Molecular Dynamics Simulation Study
E Jingwen, Ye Liu, Shanshan Guan, Zhijian Luo, Fei Han, Weiwei Han, Song Wang, Hao Zhang · 2020 · Molecules
FUT7 promotes the malignant transformation of follicular thyroid carcinoma through α1,3-fucosylation of EGF receptor
Huamin Qin, Jianwei Liu, Ming Yu, Hao Wang, Aline M. Thomas, Li Shen, Qiu Yan, Lifen Wang · 2020 · Experimental Cell Research
Autophosphorylation of EGFR at Y954 Facilitated Homodimerization and Enhanced Downstream Signals
Ovia Margaret Thirukkumaran, M. Kluba, Johan Hofkens, Hideaki Mizuno · 2020 · Biophysical Journal
A mathematical model for phenotypic heterogeneity in breast cancer with implications for therapeutic strategies
Xin Li, Dave Thirumalai · 2022 · Journal of The Royal Society Interface
STAT3 induces G9a to exacerbate HER3 expression for the survival of epidermal growth factor receptor-tyrosine kinase inhibitors in lung cancers
Yi-Fang Chang, Ken‐Hong Lim, Ya-Wen Chiang, Zong‐Lin Sie, Jungshan Chang, Ai‐Sheng Ho, Chun‐Chia Cheng · 2019 · BMC Cancer
NRG1/ERBB3/ERBB2 Axis Triggers Anchorage-Independent Growth of Basal-like/Triple-Negative Breast Cancer Cells
Carmen Miano, Alessandra Morselli, Francesca Pontis, Chiara Bongiovanni, Francesca Sacchi, Silvia Da Pra, Donatella Romaniello, Riccardo Tassinari, Michela Sgarzi, Elvira Pantano et al. · 2022 · Cancers
Involvement of microRNA-4680-3p against phenytoin-induced cell proliferation inhibition in human palate cells
Yosuke Tsukiboshi, Hanane Horita, Yurie Mikami, Azumi Noguchi, Satoshi Yokota, Kenichi Ogata, Hiroki Yoshioka · 2024 · The Journal of Toxicological Sciences
Combination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR signaling pathway
Han Wang, Xiaohui Du, Wenwen Liu, Congcong Zhang, Ying Li, Jingwen Hou, Yi Yu, Guiru Li, Qi Wang · 2024 · Respiratory Research
HER3: Updates and current biology function, targeted therapy and pathologic detecting methods
Leyi Gao, Yu Zhang, Mengna Feng, Mengjia Shen, Libo Yang, Bing Wei, Yongjie Zhou, Zhang Zhang · 2024 · Life Sciences
Extracellular domain shedding influences specific tumor uptake and organ distribution of the EGFR PET tracer 89Zr-imgatuzumab
Martin Pool, Arjan Kol, Marjolijn N. Lub–de Hooge, Christian A. Gerdes, Steven de Jong, Elisabeth G.E. de Vries, Anton G.T. Terwisscha van Scheltinga · 2016 · Oncotarget
Insulin growth factor 1 like receptor (IGF-1R)
Gopal Iyer, James Price, Shay Bourgeois, Eric A. Armstrong, Shyhmin Huang, Paul M. Harari · 2016 · BMC Cancer
Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF
Won‐Sik Shin, Hae Won Lee, Seung‐Taek Lee · 2019 · The FASEB Journal
Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours
Long Wang, Gengyuan Zhang, Long Qin, Huili Ye, Yan Wang, Bo Long, Zuoyi Jiao · 2020 · Recent Patents on Anti-Cancer Drug Discovery
The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case study
Fozia Ahmed, Michael D. Paul, Kalina A. Hristova · 2020 · Biochemical Journal
Mining Natural Products with Anticancer Biological Activity through a Systems Biology Approach
Διονυσία Θεοφυλάκτου, Işıl Takan, Gökhan Karakülah, Gökay Mehmet Biz, Vassiliki Zanni, Athanasia Pavlopoulou, Alexandros G. Georgakilas · 2021 · Oxidative Medicine and Cellular Longevity
Iterative Upgrading of Small Molecular Tyrosine Kinase Inhibitors for EGFR Mutation in NSCLC: Necessity and Perspective
Jing Zhu, Qian Yang, Weiguo Xu · 2021 · Pharmaceutics