DNA Repair, Genome Stability, and Aging

Lombard, David B., Chua, Katrin F., Mostoslavsky, Raul, Franco, Sonia, Gostissa, Monica, Alt, Frederick W.·2005·Cell
DOI 10.1016/j.cell.2005.01.028

Cited by (949)

Items 701–800 of 949

  1. Glucose Metabolism, Insulin, and Aging
    Massimo Boemi, Giorgio Furlan, Maria Paola Luconi · 2016 · Elsevier eBooks
  2. Current Knowledge on Honey and Its Derivatives with Genomic Stability: A Mini Review
    Malisanurhidayu Yaacob, Anne Jesscy Stanis, Nor Fadilah Rajab, Suzana Shahar, Razinah Sharif · 2017 · Journal of Agricultural Science
  3. Genomic Instability and DNA Repair in Cancer
    Bhaswatee Das, Bipasha Choudhury, Aditya Arun Kumar, Vishwa Jyoti Baruah · 2021 · IntechOpen eBooks
  4. Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes
    Yana Cen, Alyson M. Curry, Dawanna S. White · 2021 · Current Medicinal Chemistry
  5. Discovery of novel DNA ‐damaging agents through phenotypic screening for DNA double‐strand break
    Doudou Zhang, Takashi Shimokawa, Qianqian Guo, Shingo Dan, Yoshio Miki, Shigeaki Sunada · 2022 · Cancer Science
  6. Model of Chaperones in Aging
    J. Krøll, Jan Olof Nehlin · 2006 · Elsevier eBooks
  7. FOXO3a upregulates DNA repair activities by transcriptional activation of target genes and provides the resistance to gamma radiation and the extension of lifespan in mouse
    Gözde Inci, Madhuri Shende Warkad, Beom-Goo Kang, Sung-Ok Kim, Na-Kyung Lee, Jee‐In Heo, Seong‐Hoon Park, Jeong‐Hyun Kim, Hongjun Kang, Chae-Ha Kim et al. · 2025 · Biogerontology
  8. The impact of alterations in lamin A on genome integrity
    Alannah J. DiCintio, Alan S. Waldman · 2025 · Mutation Research/Reviews in Mutation Research
  9. Bacterial soluble secondary metabolites enhance algal tolerance to pyridine in an indirect-contact symbiotic system
    Xinying Hou, Xiaoyu Zhang, Yan Li, Muyu Li, Xinbai Jiang, Jinyou Shen, Dan Chen · 2025 · Bioresource Technology
  10. Cause and effect in epigenetics – where lies the truth, and how can experiments reveal it?
    Michael Klutstein · 2020 · BioEssays
  11. Strawberry (Fragaria ananassaduch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer’s disease
    Lada Živković, Vladan Bajić, Andrea Pirković, Dragana Dekanski, Tamara Yuliett Forbes-Hernández, Mirjana Zlatković‐Švenda, George L. Perry, Biljana Spremo‐Potparević · 2021 · Journal of Food Biochemistry
  12. Biochemistry and Protein Interactions of the CYREN Microprotein
    Lina Xie, Marianne E. Bowman, Gordon V. Louie, Cheng Zhang, Maziar S. Ardejani, Xuemei Huang, Qian Chu, Cynthia J. Donaldson, Joan M. Vaughan, Huanqi Shan et al. · 2023 · Biochemistry
  13. Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators
    Juhyung Song, Cheoljun Park, Francis Cabanting, Yong Woong Jun · 2024 · RSC Medicinal Chemistry
  14. Avian Lifespan Network Reveals Shared Mechanisms and New Key Players in Animal Longevity
    Mirko Martini, Giovanni Piccinini, Liliana Milani, Mariangela Iannello · 2025 · Aging Cell
  15. Loss of p53 Ser18 and Atm Results in Embryonic Lethality without Cooperation in Tumorigenesis
    Heather L. Armata, Punita Shroff, David Garlick, Krista L. Penta, Andrew R. Tapper, Hayla K. Sluss · 2011 · PLoS ONE
  16. Hepatocarcinogenesis in non‐cirrhotic liver is associated with a reduced number of clonal hepatocellular patches in non‐tumorous liver parenchyma
    Alexander C. Adam, Viola Faudou, Stefan A. Paschen, O. Adam, Philip Kahl, Uta Drebber, Hans‐Peter Fischer, Reinhard Büttner · 2012 · The Journal of Pathology
  17. Awakening p53 in senescent cells using nutlin-3
    Thaddeus T. Schug · 2009 · Aging
  18. The Impact of Aging on Cancer Progression and Treatment
    Shenghui He, Norman E. Sharpless · 2015 · Springer eBooks
  19. Aging of Human Haematopoietic Stem Cells
    David Garrick, Dounia Djeghloul, Klaudia Kuranda, Michèle Goodhardt · 2015 · Springer eBooks
  20. Assessing acute myeloid leukemia susceptibility in rearrangement‐driven patients by DNA breakage at topoisomerase II and CCCTC‐binding factor/cohesin binding sites
    Naomi D. Atkin, Heather M. Raimer, Zhenjia Wang, Chongzhi Zang, Yuh‐Hwa Wang · 2021 · Genes Chromosomes and Cancer
  21. Oxidatively generated DNA base modifications: Relation to eustress and distress
    Bernd Epe · 2019 · Elsevier eBooks
  22. p53 codon 72 polymorphisms and random amplified polymorphic DNA analysis of non-melanoma skin cancer through archival formalin-fixed paraffin-embedded tissue
    Yoke Kqueen Cheah · 2011 · Oncology Reports
  23. Comparative analysis of efficiency of syngeneic and allogeneic transplantation without irradiation of the EGFP+ mice bone marrow cells with the microspectral fluorescence method
    Alexey V. Karnaukhov, E. V. Karnaukhova, Larisa A. Sergievich, Н. А. Карнаухова, Е. В. Богданенко, I. A. Manokhina, V. N. Karnaukhov · 2014 · BIOPHYSICS
  24. What are the characteristics of vitamin D metabolism in opioid dependence? An exploratory longitudinal study in Australian primary care
    Albert Stuart Reece, Gary Kenneth Hulse · 2018 · BMJ Open
  25. Frequency of Spontaneous and Radiation-Induced Chromosomal Aberrations in Peripheral Blood Lymphocytes of Individuals of Different Ages
    O V Shemetun, O.A. Talan, O. M. Demchenko, D. A. Кurinnyi, M. S. Papuga, M. A. Pilinska · 2018 · Cytology and Genetics
  26. Skin Aging
    Jean Krutmann · 2010 · Springer eBooks
  27. Correction: Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease
    Takuya Tamura, Masaki Sone, Takeshi Iwatsubo, Kazuhiko Tagawa, Erich E. Wanker, Hitoshi Okazawa · 2012 · PLoS ONE
  28. Methods for In Vitro Mutagenesis
    Matteo Forloni, Alex Y. Liu, Narendra Wajapeyee · 2019 · Cold Spring Harbor Protocols
  29. Integrative multi-omics approach for identifying and classifying high-risk patients in prostate cancer management
    Mohammad Azzeh, Noor Afeshat, Hazem Qattous, Abedrahman Alkhateeb · 2025 · Neural Computing and Applications
  30. Warmer temperature accelerates senescence by modifying the aging-dependent changes in the mosquito transcriptome, altering immunity, metabolism, and DNA repair
    Martin, Lindsay E., Barr, Jordyn S., Cartailler, Jean-Philippe, Shrestha, Shristi, Estévez-Lao, Tania Y., Hillyer, Julián F. · 2025 · Immunity & Ageing
  31. The tight bond between Fanconi anemia and aging
    Marco A. Mejía-Barrera, Enya Enara Martínez-Torres, Ulises Juárez, Leda Torres, Moisés Ó. Fiesco-Roa, Benilde García‐de Teresa, Juan Carlos Gómez-Verján, Jorge Meléndez-Zajgla, Alfredo Rodríguez, Sílvia Sánchez et al. · 2026 · Frontiers in Aging
  32. Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study
    Valentina Talevi, Hang‐Mao Lee, Dan Liu, Marc Beyer, Paolo Salomoni, Monique M.B. Breteler, N. Ahmad Aziz · 2025 · Aging Cell
  33. Molekulare Mechanismen des Alterns Über das Altern der Zellen und den Einfluss von oxidativem Stress auf den Alternsprozess
    Christian Behl, Bernd Moosmann · 2008 · Springer eBooks
  34. Aging, p53 and the ‘24 gene mutant’: getting it right A reply to Vijg and Hasty
    Sundaresan Venkatachalam · 2005 · Aging Cell
  35. p53, longevity assurance and longevity suppression
    Lawrence A. Donehower · 2006 · Drug Discovery Today Disease Mechanisms
  36. Absolute and age-dependent elevations of serum calcium and phosphate and their products in clinical opiate dependence
    Albert Stuart Reece · 2013 · Journal of Substance Use
  37. The Journey of DNA Repair
    Natalie Saini · 2015 · Trends in cancer
  38. Transcriptomic alterations underline aging of osteogenic bone marrow stromal cells
    Yu‐Hao Cheng, Shu-fen Liu, Jing-Cheng Dong, Qin Bian · 2021 · World Journal of Stem Cells
  39. AI in Longevity Medicine
    Dina Radenković, Alex A. Zhavoronkov, Evelyne Yehudit Bischof · 2021 · Springer eBooks
  40. Age-related decline in the expression of BRG1, ATM and ATR are partially reversed by dietary restriction in the livers of female mice
    Pynskhem Bok Swer, Babiangshisha Kharbuli, Donkupar Syiem, Ramesh Sharma · 2024 · Biogerontology
  41. O6-Methylguanine-DNA methyltransferase (MGMT) gene expression is associated with ultraviolet B (UVB)-induced cell growth inhibition and recovery
    Juyeon Lee, Ki‐Jong Rhee, Sung Hoon Kim, Yeo Wool Kang, Yoonjung Cho, Seung-Ju Yang, Cheol‐Ho Pan, Yoon Suk Kim · 2015 · Genes & Genomics
  42. 1, Structural and Functional Studies of Human Replication Protein A; 2 DNA Damage Responses and DNA Repair Defects in Laminopathy-Based Premature Aging.
    Yiyong Liu · 2007 · Digital Commons - East Tennessee State University (East Tennessee State University)
  43. Fragile DNA Repair Mechanism Reduces Ageing in Multicellular Model
    Kristian Moss Bendtsen, Jeppe Juul, Ala Trusina · 2012 · PLoS ONE
  44. Non homologous end joining-mediated DNA break repair is impaired in B lymphocytes of aging mice
    Abdul Gafoor Puthiyaveetil, David L. Caudell · 2012 · Molecular Immunology
  45. Fine mapping and functional activity of the adenosine deaminase origin in murine embryonic fibroblasts
    Sahar Sibani, Emmanouil Rampakakis, Domenic Di Paola, Maria Zannis‐Hadjopoulos · 2008 · Journal of Cellular Biochemistry
  46. Theories and Mechanisms of Aging
    Christian Behl, Christine Ziegler · 2013 · SpringerBriefs in molecular medicine
  47. Comparative Biology of Aging
    Michael Van Meter, Vera A. Gorbunova, Andrei Seluanov · 2015 · Elsevier eBooks
  48. Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington’s disease
    Ross Ferguson, Robert Goold, Lucy A. Coupland, Michael D. Flower, Sarah J. Tabrizi · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  49. Mechanisms of genome instability in Hutchinson-Gilford progeria
    Haoyue Zhang, Kan Cao · 2016 · Frontiers in Biology
  50. DNA damage repair molecular subtype derived immune signature applicable for the prognosis and immunotherapy response prediction in colon cancer
    Zhen Shang, Ze Wang, Yongtao Zhang, Shanglong Liu · 2023 · Translational Cancer Research
  51. Biophysical investigation of the molecular interaction between minichromosome maintenance protein 6 and Bloom syndrome helicase
    Min June Yang, HaEun Lee, Donguk Kang, Chin-Ju Park · 2025 · The FEBS Journal
  52. Aging and the Spectral Properties of Brain Hemodynamics
    Ki Yun Park, Abraham Z. Snyder, Manu S. Goyal, Timothy O. Laumann, John J. Lee, Babatunde Adeyemo, Nicholas V. Metcalf, Andrei G. Vlassenko, Joshua S. Shimony, Eric C. Leuthardt · 2025 · Advanced Science
  53. Postprandial implications in cardiovascular disease and potential markers to develop new therapies
    Irina Florina Tudorache, Davide Barbarossa, Bianca Sânziana Daraban, Riccardo Rizzo, Francesco Maria Esposito, Maurizio Maria Coronelli, Alberico Luigi Catapano · 2025 · European Atherosclerosis Journal
  54. Leukocyte telomere length and risk of heart failure with preserved ejection fraction in high-risk Chinese patients with hypertension under 65 years
    Alian Zhang, Zhengde Tang, Alex Chia Yu Chang, Jun Fei Gu, Junfeng Zhang, Zhuo Yang, Huili Zhang · 2025 · GeroScience
  55. The Value of CT Vascular Sign in Differentiating Benign and Malignant Solid Pulmonary Nodules
    Yu Peng, Yin Lan, Tianyou Luo, Qi Li · 2025 · Academic Radiology
  56. Genetic architecture of human aging and longevity: Insights from genome-wide association studies
    Dabin Yoon, Jungsoo Gim · 2026 · BMB Reports
  57. Caffeine inhibits nonhomologous end joining by impairing ligase IV/XRCC4 function
    Susmita Kumari, Divya Sathees, Prashant Kumar, Lipsa Rani Sahu, Sathees C. Raghavan · 2026 · Nucleic Acids Research
  58. Aging and cancer: current understandings and future perspectives
    Qi Li, Yau-Tuen Chan, Junyu Wu, Zhuofeng Jiang, Pengde Lu, Lin Xu, Zixin Feng, Hongchao Yuan, Yibin Feng, Ning Wang · 2026 · Signal Transduction and Targeted Therapy
  59. Fatty acid tryptamide from cacao elongates Drosophila melanogaster lifespan with sirtuin-dependent heat shock protein expression
    Kiko Kanno, Yasunari Kayashima, Kazuji TAMURA, Takako Miyara, Kento Baba, Megumi Koganei, Midori Natsume, Shinjiro Imai · 2022 · Scientific Reports
  60. Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
    Sharath Anugula, Zhiquan Li, Yuan Li, Alexander Hendriksen, Peter Bjarn Christensen, Lin Wang, Jonathan M. Monk, Niels de Wind, Vilhelm A. Bohr, Claus Desler et al. · 2023 · Heliyon
  61. Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence
    Yi-Nan Jiang, Yizhen Gao, Xianxin Lai, Xinjie Li, Gen Liu, Mingmei Ding, Zhiyi Wang, Zixiang Guo, Yinying Qin, Xin Li et al. · 2024 · International Journal of Molecular Sciences
  62. The role of different physical exercises as an anti-aging factor in different stem cells
    Jiajia Xu, Zhe Song · 2025 · Biogerontology
  63. Role of Signaling Pathways Regulating Genomic Stability in Cancer
    A. Sheikh, G. A. Bhat, Sukhdeep Kumar, Syed Mudassar · 2025 · Springer eBooks
  64. Natural Antioxidants and Their Impact on Aging
    Saliya S. Bawani, Rakesh Hanumanthappa, Rizwan Sharief · 2025 · IGI Global eBooks
  65. Using the safety scissors: DNA resection regulation at DNA double-strand breaks and telomeres
    Michael M. Soniat, Logan R. Myler · 2025 · DNA repair
  66. Role of Epigenetics in Transgenerational Changes: Genome Stability in Response to Plant Stress
    Igor Kovalchuk · 2018 · Signaling and communication in plants
  67. Cell Cycle Control and Replication in Corneal Endothelium
    Nancy C. Joyce · 2010 · Essentials in ophthalmology/Essentials ophthalmology
  68. Chromatin Remodeling in DNA Damage Response and Human Aging
    Lili Gong, Edward Wang, Shiaw-Yih Li · 2013 · InTech eBooks
  69. The biological time calendar
    Huynh Thien Duc · 2014 · Biomedicine & Aging Pathology
  70. El nucléolo como un regulador del envejecimiento celular
    María Rosete-Enríquez, María Rosa Padrós, Osvaldo Vindrola · 2007 · Medicina-buenos Aires
  71. The Stem Cell Hypothesis of Aging
    Anna Meiliana, Andi Wijaya · 2010 · The Indonesian Biomedical Journal
  72. Aging Heart: Recent Research and Concepts
    Vinod Nikhra · 2017 · Gerontology & Geriatrics Studies
  73. Traditional Indian sports – A case-control study on Kho Kho players investigating genomic instability and oxidative stress as a function of metabolic genotypes
    Gursatej Gandhi, Resham Sharma, Gurpreet Kaur · 2019 · Heliyon
  74. Supraphysiological protection from replication stress does not extend mammalian lifespan
    Eliene Albers, Alexandra Avram, Mauro Sbroggió, Óscar Fernández-Capetillo, Andres Joaquin Lopez-Contreras · 2020 · Aging
  75. Senolytics Target Senescent Cells and Improve Aging and Age-Related Diseases
    Tony Buffard, Gerardo Ferbeyre · 2020 · Healthy ageing and longevity
  76. Sequence selective tagging of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) using PNAs
    In Seok Hong, Marc M. Greenberg · 2015 · Bioorganic & Medicinal Chemistry Letters
  77. Environment, Epigenetics, and the Pace of Human Aging
    Elisabeth A. Goldman, Kirstin N. Sterner · 2023 · Annual Review of Anthropology
  78. Modifiers of Neural Stem Cells and Aging: Pulling the Trigger of a Neurogenic Decline
    Emmanuel Nivet · 2016 · Current Stem Cell Reports
  79. Novel nanotech antioxidant cocktail prevents medical diagnostic procedures ionizing radiation effects
    Miguel Gorenberg, Abed Agbarya, David Groshar, Ilya Volovik, Ofir Avitan, Igor Sukhotnik · 2021 · Scientific Reports
  80. Mouse Models of Accelerated Aging
    Jan Vijg, Paul Hasty · 2006 · Elsevier eBooks
  81. Forever young, slim and fit: Rapamycin to the rescue
    Zbigniew Darżynkiewicz · 2009 · Cell Cycle
  82. Characterization of the multifunctional XPG protein during Nucleotide-excision-repair
    Steffen Schubert · 2014
  83. Longitudinal Analyses Reveal That Aging-related Alterations in the Intestinal Environment Lead to Gut Dysbiosis With the Potential to Induce Obesity
    Yumiko Nakanishi, Ryouko Nozu, Masami Ueno, Kyoji Hioki, Chiharu Ishii, Shinnosuke Murakami, Kenta M. Suzuki, Yuyo Ka, Tomoyuki Ogura, Ayumi Ito et al. · 2020 · Research Square
  84. Neurodegeneration-associated instability of ribosomal DNA.
    Justin Hallgren · 2014
  85. Hormetic effects of mild heat stress on the primary culture of mouse prefrontal cerebrocortical neurons
    Narayan R. Mane, Kavita Amrut Gajare, Ashish A. Deshmukh · 2020 · The Journal of Basic and Applied Zoology
  86. Progress in human embryonic stem cell research and aging
    Anjali P. Patni, Joel P. Joseph, Dannie Macrin, Arikketh Devi · 2021 · Elsevier eBooks
  87. Biological variables and their potential impact on biomarkers and precision medicine initiative
    Abdel B Halim · 2019 · Elsevier eBooks
  88. Cell-to-Cell Communication in Aging: Mechanisms, Impact and Therapeutic Prospects
    Cristina Mas‐Bargues, Jorge Sanz‐Ros, Javier Huete-Acevedo, Consuelo Borrás · 2024 · Springer eBooks
  89. Amodiaquine ameliorates stress-induced premature cellular senescence via promoting SIRT1-mediated HR repair
    Jie Du, Fuqiang Chen, Chenghong Du, Wenna Zhao, Zihan Chen, Zhenhua Ding, Meijuan Zhou · 2024 · Cell Death Discovery
  90. Multivalent cannabinoid epigenotoxicities and multigenerational aging
    Albert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
  91. Latency, microenvironment, and the priming of a precancerous senescent cell for malignant transformation
    April Kirkendoll · 2025 · Advances in Cancer Biology - Metastasis
  92. Yaşlanmanın Fizyolojik Temelleri: Vücudun Zamanla Değişen Dengesi
    Halil Şimşek, Fatih Çakar · 2025 · Bingöl Üniversitesi Sağlık Dergisi
  93. Preventing effect of plant extracts and omega-3 on age-related cognitive decline in male mice
    Marie Martin, Adrien Peltier, Heena Vanmalibhai Lad, Aline Foury, Charlotte Madore-Delpech, Line Pourtau, David Gaudout, Sophie Layé, Véronique Pallet, Anne‐Laure Dinel et al. · 2025 · Brain Behavior & Immunity - Health
  94. Beyond the hallmarks of aging: Rethinking what aging is and how we measure it
    Maryam Keshavarz, Dan Ehninger · 2025 · Genomic psychiatry :
  95. The Emerging Role of Senolytics as a Next-Generation Strategy Against Glioma Recurrence: A Narrative Review
    Andrea Filardo, Isabella Coscarella, Jessica Bria, Anna Di Vito, Domenico La Torre, Emanuela Chiarella, Adele Giovinazzo, Emanuela Procopio, Maria Teresa Egiziano, Angelo Lavano et al. · 2026 · Cancers
  96. DNA and RNA Damage, Protection, and Repair in Desiccation-Tolerant Metazoans
    Maria Kamilari, Nadja Møbjerg, Nikos T. Papadopoulos, Antonios A. Augustinos · 2026 · Biomolecules
  97. From Seed to Tree: The Functioning and Evolution of DNA Repair in Plants
    Jaana Vuosku, Marko Suokas, Johanna Kestilä, Tytti Sarjala, Hely Haggm · 2011 · InTech eBooks
  98. Effect of moderate diet restriction on body condition, health, and reproductive longevity in female mink (Neovison vison)
    Laura Boudreau, Bernhard F. Benkel, Kirsti Rouvinen‐Watt · 2011
  99. Neural Stem Cells and Demyelinating Disease
    Abbe Harper Crawford, Robin J.M. Franklin · 2014 · Stem cell biology and regenerative medicine
  100. Aging of Stem Cells in Skin: What Is Driving the Aging Process?
    Sabrina Gundermann, Hans‐Jürgen Stark, Petra Boukamp · 2015 · Springer eBooks