PCNA, the Maestro of the Replication Fork
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- Toxoplasma gondii Extends the Life Span of Infected Human Neutrophils by Inducing Cytosolic PCNA and Blocking Activation of Apoptotic CaspasesTatiane Soares de Lima, Sharmila Mallya, Allen Jankeel, Ilhem Messaoudi, Melissa B. Lodoen · 2021 · mBio
- Small Proteins in Archaea, a Mainly Unexplored WorldKatrin Weidenbach, Miriam Gutt, Liam Cassidy, Cynthia Maria Chibani, Ruth A. Schmitz · 2021 · Journal of Bacteriology
- Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21WAF1, Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cellsHong Zhao, Sufang Zhang, Dazhong Xu, Marietta Y. Lee, Zhongtao Zhang, Ernest YC Lee, Zbigniew Darżynkiewicz · 2014 · Cell Cycle
- Diversity of the DNA Replication System in the Archaea DomainFelipe Sarmiento, Feng Long, Isaac Cann, William B. Whitman · 2014 · Archaea
- Assembly and Distributive Action of an Archaeal DNA Polymerase HoloenzymeRobert J. Bauer, Ian D. Wolff, Xiaobing Zuo, Hsiang-Kai Lin, Michael A. Trakselis · 2013 · Journal of Molecular Biology
- Human RAD18 Interacts with Ubiquitylated Chromatin Components and Facilitates RAD9 Recruitment to DNA Double Strand BreaksAkiko Inagaki, Esther Sleddens–Linkels, Wiggert A. van Cappellen, Richard G. Hibbert, Titia K. Sixma, Jan H.J. Hoeijmakers, J. Anton Grootegoed, Willy M. Baarends · 2011 · PLoS ONE
- Hepatocellular carcinoma: prevalence and molecular pathogenesis ofHelicobacterspp.Quoc V. Tu, Arinze Stanley Okoli, Zsuzsanna Kovách, George Louis Mendz · 2009 · Future Microbiology
- Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repairAkiko Inagaki, Wiggert A. van Cappellen, Roald van der Laan, Adriaan B. Houtsmuller, Jan H.J. Hoeijmakers, J. Anton Grootegoed, Willy M. Baarends · 2008 · DNA repair
- Structure of a DNA Polymerase α-Primase Domain That Docks on the SV40 Helicase and Activates the Viral PrimosomeHao Huang, Brian E. Weiner, Haijiang Zhang, Brian E. Fuller, Yue Gao, Brian M. Wile, Kun Zhao, Diana R. Arnett, Walter Chazin, Ellen Fanning · 2010 · Journal of Biological Chemistry
- The Role of PCNA Posttranslational Modifications in Translesion SynthesisMontaser F. Shaheen, Ilanchezhian Shanmugam, Robert Hromas · 2010 · Journal of Nucleic Acids
- Characterization of cytosolic proliferating cell nuclear antigen (PCNA) in neutrophils: antiapoptotic role of the monomerAlessia De Chiara, Magali Pederzoli-Ribeil, Julie Mocek, Céline Candalh, Patrick Mayeux, Arnaud Millet, Véronique Witko‐Sarsat · 2013 · Journal of Leukocyte Biology
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- Identification of genes associated with melanoma metastasisTao Qiu, Hongyi Wang, Yang Wang, Yu Zhang, Qiang Hui, Kai Xiong Tao · 2015 · The Kaohsiung Journal of Medical Sciences
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- Genome size‐dependent pcna gene copy number in dinoflagellates and molecular evidence of retroposition as a major evolutionary mechanismYubo Hou, Nanjing Ji, Huan Zhang, Xinguo Shi, Hansen Han, Senjie Lin · 2018 · Journal of Phycology
- USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication forkAndré Franz, Pablo Valledor, Patricia Ubieto‐Capella, Domenic Pilger, Antonio Galarreta, Vanesa Lafarga, Alejandro Fernández-Llorente, Guillermo de la Vega-Barranco, Fabian den Brave, Thorsten Hoppe et al. · 2021 · Cell Reports
- Compartmentalization of the replication fork by single-stranded DNA-binding protein regulates translesion synthesisSeungwoo Chang, Elizabeth S. Thrall, Luisa Laureti, Sadie C. Piatt, Vincent Pagès, Joseph J. Loparo · 2022 · Nature Structural & Molecular Biology
- Human C6orf211 Encodes Armt1, a Protein Carboxyl Methyltransferase that Targets PCNA and Is Linked to the DNA Damage ResponseJ. Jefferson P. Perry, Gregory D. Ballard, Alexandra E. Albert, Lacey Elizabeth Dobrolecki, Linda H. Malkas, Derek J. Hoelz · 2015 · Cell Reports
- The Mechanical Properties of PCNA: Implications for the Loading and Function of a DNA Sliding ClampJoshua L. Adelman, John D. Chodera, I-Feng William Kuo, Thomas F. Miller, Daniel Barsky · 2010 · Biophysical Journal
- RNA interference-mediated silencing of NANOG leads to reduced proliferation and self-renewal, cell cycle arrest and apoptosis in T-cell acute lymphoblastic leukemia cells via the p53 signaling pathwayJiang Cao, Li Li, Chong Chen, Chao Lv, Fanjing Meng, Lingyu Zeng, Zhenyu Li, Qing‐Yun Wu, Kai Zhao, Bin Pan et al. · 2013 · Leukemia Research
- PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesionPsakhye, Ivan, Kawasumi, Ryotaro, Abe, Takuya, Hirota, Kouji, Branzei, Dana · 2023 · Nature Structural & Molecular Biology
- Effect of estrogen and dietary loading on condylar cartilage.Marko Orajärvi, Elina Puijola, Shibin Yu, Xiaodong Liu, Petri A. Tiilikainen, Meiqing Wang, Aune M. Raustia, Pertti M. Pirttiniemi · 2012 · PubMed
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- DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication ForksKartika Venugopal, Yang Feng, Paweł Nowialis, Huanzhou Xu, Daniil E. Shabashvili, Cassandra M. Berntsen, Prabhjot Kaur, Kathryn I. Krajcik, Christina Taragjini, Zachary Zaroogian et al. · 2021 · Clinical Cancer Research
- SUMOylation regulates low‐temperature survival and oxidative DNA damage tolerance in Botrytis cinereaWenyong Shao, Kewei Sun, Tianling Ma, Huixian Jiang, Matthias Hahn, Zhonghua Ma, Chen Jiao, Yanni Yin · 2023 · New Phytologist
- The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell LineagesRubén Cereijo, José Miguel Gallego-Escuredo, Ricardo Moure, Joan Villarroya, Joan Carles Domingo, Joan Fontdevila, Estebán Martínez, María del Mar Gutiérrez, Gracia María Mateo, Marta Giralt et al. · 2015 · PLoS ONE
- Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54Blair L. Strang, Donald M. Coen · 2010 · Journal of General Virology
- Distinct Structural Alterations in Proliferating Cell Nuclear Antigen Block DNA Mismatch RepairLynne M. Dieckman, Elizabeth M. Boehm, Manju Hingorani, M. Todd Washington · 2013 · Biochemistry
- Comparative analysis of pre‐replication complex proteins in transformed and normal cellsDomenic Di Paola, Maria Zannis‐Hadjopoulos · 2011 · Journal of Cellular Biochemistry
- Linking DNA replication to heterochromatin silencing and epigenetic inheritanceQing Li, Zhiguo Zhang · 2011 · Acta Biochimica et Biophysica Sinica
- Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatinZhihui Liang, Marc Diamond, Johanna A. Smith, Matthias J. Schnell, René Daniel · 2011 · Epigenetics & Chromatin
- PARP10 deficiency manifests by severe developmental delay and DNA repair defectMaher Awni Shahrour, Claudia M. Nicolae, Simon Edvardson, Motee Ashhab, Adri M. Galvan, Daniel Constantin, Bassam Abu‐Libdeh, George‐Lucian Moldovan, Orly N Elpeleg · 2016 · Neurogenetics
- Growth hormone‐releasing hormone receptor antagonists modify molecular machinery in the progression of prostate cancerLaura Muñoz‐Moreno, Andrew Victor Schally, Juan Carlos Prieto, María José Carmena, Ana Maria Bajo · 2018 · The Prostate
- Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forksJulie Rageul, Jennifer J. Park, Ukhyun Jo, Alexandra S. Weinheimer, Tri T. M. Vu, Hyungjin Kim · 2019 · Nucleic Acids Research
- The Fanconi anemia protein interaction network: Casting a wide netMeghan A. Rego, Frederick W. Kolling, Niall G. Howlett · 2008 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)Amaia Gonzalez Magaña, Alain Ibáñez de Opakua, Miguel Romano‐Moreno, Javier Murciano‐Calles, Nekane Merino, Irene Luque, Adriana Lucely Rojas, Silvia Onesti, Francisco J. Blanco, Alfredo De Biasio · 2019 · Journal of Biological Chemistry
- Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFCQing He, Feng Wang, Mike E. O’Donnell, Huilin Li · 2024 · Proceedings of the National Academy of Sciences
- DNA repair systems in malignant mesotheliomaDimitrios Toumpanakis, Stamatios E Theocharis · 2011 · Cancer Letters
- A Novel Anticancer Agent, SKLB70359, Inhibits Human Hepatic Carcinoma Cells proliferation via G0/G1 Cell Cycle Arrest and Apoptosis InductionXiaoyun Dai, Xiu‐Xiu Zeng, Feng Peng, Yuanyuan Han, Hongjun Lin, Youzhi Xu, Tian Zhou, Gang Xie ., Yi Deng, Yong-Qiu Mao et al. · 2012 · Cellular Physiology and Biochemistry
- Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forksThomas Schleker, Shigeki Nagai, Susan M. Gasser · 2009 · DNA repair
- α-lipoic acid exerts neuroprotective effects on neuronal cells by upregulating the expression of PCNA via the P53 pathway in neurodegenerative conditionsDa‐Wei Li, Ying-Di Wang, Shiyao Zhou, Wenping Sun · 2016 · Molecular Medicine Reports
- Understanding photodermatoses associated with defective DNA repairCerrene N. Giordano, Yik Weng Yew, Graciela Spivak, Henry W. Lim · 2016 · Journal of the American Academy of Dermatology
- Paths from DNA damage and signaling to genome rearrangements via homologous recombinationJac A. Nickoloff · 2017 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in MiceAyako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai, Minoru Takata, Gen Kondoh, Hitomi Watanabe et al. · 2017 · Molecular and Cellular Biology
- P53 at the start of the 21st century: lessons from elephantsSue Haupt, Ygal Haupt · 2017 · F1000Research
- Curcumin restores hepatic epigenetic changes in propylthiouracil(PTU)Induced hypothyroid male rats: A study on DNMTs, MBDs, GADD45a, C/EBP-β and PCNASuresh Kumar Bunker, Abinash Dutta, Jyotsnarani Pradhan, Jagneshwar Dandapat, G.B.N. Chainy · 2018 · Food and Chemical Toxicology
- MicroRNA-204 inhibits the proliferation, migration and invasion of human lung cancer cells by targeting PCNA-1 and inhibits tumor growth in vivoPing Li, Qingan Wang, Haining Wang · 2018 · International Journal of Molecular Medicine · Retracted
- Binding of the regulatory domain of MutL to the sliding β-clamp is species specificAhmad W. Almawi, Michelle K. Scotland, Justin R. Randall, Linda L. Liu, Heather K Martin, Lauralicia Sacre, Yao Shen, Monica C. Pillon, Lyle A. Simmons, Mark D. Sutton et al. · 2019 · Nucleic Acids Research
- Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapyCaroline Krogh Søgaard, Anala Nepal, Voin Petrović, Animesh Sharma, Nina‐Beate Liabakk, Tonje S. Steigedal, Marit Otterlei · 2019 · Oncotarget
- Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junctionSubu Subramanian, Kent Gorday, Kendra Marcus, Matthew R. Orellana, Peter Ren, Xiao Ran Luo, Mike E. O’Donnell, John Kuriyan · 2021 · eLife
- Archaeal Genome Guardians Give Insights into Eukaryotic DNA Replication and Damage Response ProteinsDavid S. Shin, Ashley J. Pratt, John A. Tainer · 2014 · Archaea
- Characterization of the Proliferating Cell Nuclear Antigen of Leishmania donovani Clinical Isolates and Its Association with Antimony ResistanceRati Tandon, Sharat Chandra, Rajendra Kumar Baharia, Sanchita Das, Pragya Misra, Awanish Kumar, Mohammad Imran Siddiqi, Shyam Sundar, Anuradha Dube · 2014 · Antimicrobial Agents and Chemotherapy
- A novel cell permeable DNA replication and repair markerHenry David Herce, Malini Rajan, Gisela Lättig-Tünnemann, Marion Fillies, M. Cristina Cardoso · 2014 · Nucleus
- The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transitionFu Huang, Anita Saraf, Laurence A. Florens, Thomas Kusch, Selene K. Swanson, Leanne T. Szerszen, Ge Li, Arnob Dutta, Michael P. Washburn, Susan M. Abmayr et al. · 2016 · Genes & Development
- A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNALiu, Xingchen, Gaubitz, Christl, Pajak, Joshua, Kelch, Brian A · 2022 · eLife
- Flexibility of PCNA-Protein Interface Accommodates Differential Binding PartnersAnthony M. Pedley, Markus A. Lill, Vincent Jo Davisson · 2014 · PLoS ONE
- Bub1 in Complex with LANA Recruits PCNA To Regulate Kaposi's Sarcoma-Associated Herpesvirus Latent Replication and DNA Translesion SynthesisZhiguo Sun, Hem Chandra Jha, Erle S. Robertson · 2015 · Journal of Virology
- The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase εAlicja Winczura, Rowin Appanah, Michael H. Tatham, Ronald T. Hay, Giacomo De Piccoli · 2019 · PLoS Genetics
- GPR30 mediated effects of boron on rat spleen lymphocyte proliferation, apoptosis, and immune functionChenfang Wang, Erhui Jin, Juan Deng, Yaqiong Pei, Man Ren, Qianqian Hu, GU You-fang, Shenghe Li · 2020 · Food and Chemical Toxicology
- Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidationMaría del Carmen Guerrero Arroyo, Florian D. Hastert, Andreas Zhadan, Florian Schelter, Susanne Zimbelmann, Cathia Rausch, Anne Kathrin Ludwig, Thomas Carell, M. Cristina Cardoso · 2022 · Nature Communications
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- Roles of DNA Helicases in the Mediation and Regulation of Homologous RecombinationJames M. Daley, Hengyao Niu, Patrick Sung · 2012 · Advances in experimental medicine and biology
- Ubiquitylation of Proliferating Cell Nuclear Antigen and Recruitment of Human DNA Polymerase ηNana Nikolaishvili‐Feinberg, G. Scott Jenkins, Kathleen R. Nevis, Dean P. Staus, Cameron O. Scarlett, Keziban Ünsal-Kaçmaz, William K. Kaufmann, Marila Cordeiro‐Stone · 2008 · Biochemistry
- The role of the DNA sliding clamp in Okazaki fragment maturation in archaea and eukaryotesThomas R. Beattie, Stephen D. Bell · 2011 · Biochemical Society Transactions
- Expression of a novel peptide derived from PCNA damages DNA and reverses cisplatin resistanceRobert G. Lingeman, Robert J. Hickey, Linda H. Malkas · 2014 · Cancer Chemotherapy and Pharmacology
- Sulindac and Celecoxib Regulate Cell Cycle Progression by p53/p21 Up Regulation to Induce Apoptosis During Initial Stages of Experimental Colorectal CancerVivek Vaish, Chandan Rana, Honit Piplani, Kim Vaiphei, Sankar Nath Sanyal · 2013 · Cell Biochemistry and Biophysics
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- Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA ReplicationMaïlyn Yates, Alexandre Maréchal · 2018 · International Journal of Molecular Sciences
- DNA polymerase η contributes to genome-wide lagging strand synthesisKatrin Kreisel, Martin K. M. Engqvist, Josephine Kalm, Liam J. Thompson, Martin Boström, Clara Navarrete, John P. McDonald, Erik Larsson, Roger Woodgate, Anders R. Clausen · 2018 · Nucleic Acids Research
- Overexpression and Implications of Melanoma-associated Antigen A12 in Pathogenesis of Human Cutaneous Squamous Cell CarcinomaGuohua Zhao, Jung Yoon Bae, Zhenlong Zheng, Hae Seok Park, Kee Yang Chung, Mi Ryung Roh, Zhehu Jin · 2019 · Anticancer Research
- Proliferating cell nuclear antigen-agarose column: A tag-free and tag-dependent tool for protein purification affinity chromatographyMuhammad Tehseen, Vlad‐Stefan Raducanu, Fahad Rashid, Afnan Shirbini, Masateru Takahashi, Samir M. Hamdan · 2019 · Journal of Chromatography A
- Nucleosome Remodeling by Fun30SMARCAD1 in the DNA Damage ResponseSusanne C. S. Bantele, Boris Pfander · 2019 · Frontiers in Molecular Biosciences
- Discovery of Inhibitors for Proliferating Cell Nuclear Antigen Using a Computational-Based Linked-Multiple-Fragment ScreenMatthew D. Bartolowits, Jonathon M. Gast, Ashlee J. Hasler, Anthony M. Cirrincione, Rachel J. O’Connor, Amr Hamed Mahmoud, Markus A. Lill, Vincent Jo Davisson · 2019 · ACS Omega
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- Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor PTGDRBrigette L. Tippin, Alan M. Kwong, Michael J. Inadomi, Oliver J. Lee, Jae Man Park, Alicia M. Materi, Virgilio S. Buslon, Amy M. Lin, Lili C. Kudo, Stanislav L. Karsten et al. · 2014 · Cancer Medicine
- The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid AssemblyJon Gil-Ranedo, Eva Hernando, Laura Riolobos, Carlos Domínguez, Michael Kann, José María Almendral · 2015 · PLoS Pathogens
- Efficient Parvovirus Replication Requires CRL4Cdt2-Targeted Depletion of p21 to Prevent Its Inhibitory Interaction with PCNARichard O. Adeyemi, Matthew S. Fuller, David J. Pintel · 2014 · PLoS Pathogens
- Engineering processive DNA polymerases with maximum benefit at minimum costLinda J. Reha-Krantz, Sandra Woodgate, Myron F. Goodman · 2014 · Frontiers in Microbiology
- Functional Dissection of the Catalytic Carboxyl-Terminal Domain of Origin Recognition Complex Subunit 1 (PfORC1) of the Human Malaria Parasite Plasmodium falciparumAshish K. Gupta, Parul Mehra, Abhijeet P. Deshmukh, Ashraf Dar, Pallabi Mitra, Nilanjan Roy, Suman Kumar Dhar · 2009 · Eukaryotic Cell
- A Distal to Proximal Gradient of Human Choroid Plexus Development, with Antagonistic Expression of Glut1 and AQP1 in Mature Cells vs. Calbindin and PCNA in Proliferative CellsLeandro Castañeyra-Ruiz, Ibrahim González-Marrero, Luís G. Hernández-Abad, Emilia M. Carmona-Calero, Gundela Meyer, Agustín Castañeyra-Perdomo · 2016 · Frontiers in Neuroanatomy
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- Secondary Interaction Interfaces with PCNA Control Conformational Switching of DNA Polymerase PolB from Polymerization to EditingXiaojun Xu, Chunli Yan, Bradley R. Kossmann, Ivaylo N. Ivanov · 2016 · The Journal of Physical Chemistry B
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- Characterization of Leishmania donovani MCM4: Expression Patterns and Interaction with PCNANeha Minocha, Devanand Kumar, Kalpana Rajanala, Swati Saha · 2011 · PLoS ONE
- The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligaseMartina Olivero, Daniela Dettori, Sabrina Arena, Davide Zecchin, Erica Lantelme, Maria Flavia Di Renzo · 2014 · Oncotarget
- Dynamic changes in chromatin structure through post‐translational modifications of histone H3 during replication origin activationEmmanouil Rampakakis, Domenic Di Paola, Man Kid Chan, Maria Zannis‐Hadjopoulos · 2009 · Journal of Cellular Biochemistry
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