Emotion Enhances Learning via Norepinephrine Regulation of AMPA-Receptor Trafficking

Hu, Hailan, Real, Eleonore, Takamiya, Kogo, Kang, Myoung-Goo, Ledoux, Joseph, Huganir, Richard L., Malinow, Roberto·2007·Cell
DOI 10.1016/j.cell.2007.09.017

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  70. References
    2012 · Wiley eBooks
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    Marina E. Wolf · 2013 · Springer eBooks
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  86. Biometric system to prevent unauthorized access through facial and emotional recognition in critical environments
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  89. BrainConnect: processing brain connectivity and spatial transcriptomics data for integrative analysis
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  90. Neurophysiological bases of memory formation and consolidation : contents and dynamics of hippocampal cell assembly sequences in rats
    Céline Drieu · 2017 · theses.fr (ABES)
  91. Neuroprotective effects of voluntary exercise and monoaminergic modulators in stressed male rats
    Sarawut Lapmanee · 2017
  92. Temporal coding expands the bandwidth of GPCR-mediated neuromodulation
    Xinyi Jenny He, Mark von Zastrow · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Voluntary Exercise and Hippocampal Memory Enhancement: Decoding the Molecular Blueprint
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  95. Synaptic plasticity processes underlying consolidation and reconsolidation of Pavlovian conditioning
    Peter Thomas Rigby · 2012 · The University of Bath Online Publications Store (The University of Bath)
  96. Autoregulatory and Paracrine Control of Synaptic and Behavioral Plasticity by Dual Modes of Octopaminergic Signaling: A Dissertation
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