The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing
Open accessAbstract
Summary A complete mitochondrial (mt) genome sequence was reconstructed from a 38,000-year-old Neandertal individual using 8,341 mtDNA sequences identified among 4.8 Gb of DNA generated from ~0.3 grams of bone. Analysis of the assembled sequence unequivocally establishes that the Neandertal mtDNA falls outside the variation of extant human mtDNAs and allows an estimate of the divergence date between the two mtDNA lineages of 660,000±140,000 years. Of the 13 proteins encoded in the mtDNA, subunit 2 of cytochrome c oxidase of the mitochondrial electron transport chain has experienced the largest number of amino acid substitutions in human ancestors since the separation from Neandertals. There is evidence that purifying selection in the Neandertal mtDNA was reduced compared to other primate lineages suggesting that the effective population size of Neandertals was small.
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MrBayes 3: Bayesian phylogenetic inference under mixed models
Ronquist, F., & Huelsenbeck, J. P. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btg180 · Cited by 29,077
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
Stamatakis, A. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl446 · Cited by 15,582
PAML 4: Phylogenetic Analysis by Maximum Likelihood
Yang, Z. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm088 · Cited by 13,879
PAUP^* : Phylogenetic Analysis Using Parsimony (and other methods) 4.0b8
Swofford, D. L. (2001) · Cited by 12,789
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Edgar, R. C. (2004) · BMC Bioinformatics · doi:10.1186/1471-2105-5-113 · Cited by 8,970
DnaSP, DNA polymorphism analyses by the coalescent and other methods
Rozas, J., Sánchez-DelBarrio, J. C., Messeguer, X., & Rozas, R. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btg359 · Cited by 6,131
A Greedy Algorithm for Aligning DNA Sequences
Zhang, Z., Schwartz, S., Wagner, L., & Miller, W. (2000) · Journal of Computational Biology · doi:10.1089/10665270050081478 · Cited by 5,478
PAML: a program package for phylogenetic analysis by maximum likelihood
Yang, Z. (1997) · Bioinformatics · doi:10.1093/bioinformatics/13.5.555 · Cited by 5,373
CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION
MITCHELL, P. (1966) · Biological Reviews · doi:10.1111/j.1469-185x.1966.tb01501.x · Cited by 3,663
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
Andrews, R. M., Kubacka, I., Chinnery, P. F., Lightowlers, R. N., Turnbull, D. M., & Howell, N. (1999) · Nature Genetics · doi:10.1038/13779 · Cited by 3,337
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Self-citationThe complete genome sequence of a Neanderthal from the Altai Mountains
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Self-citationGenetic history of an archaic hominin group from Denisova Cave in Siberia
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Self-citationA high-coverage genome sequence from an archaic denisovan individual
Meyer, M., Kircher, M., Gansauge, M.-T., Li, H., Racimo, F., Mallick, S., Schraiber, J. G., Jay, F., Prüfer, K., de Filippo, C., et al. (2012) · Science · doi:10.1126/science.1224344 · Cited by 1,967
Self-citationTesting for ancient admixture between closely related populations
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Metadata
- Authors
- Green, R. E., Malaspinas, A.-S., Krause, J., Briggs, A. W., Johnson, P. L. F., Uhler, C., Meyer, M., Good, J. M., Maricic, T., Stenzel, U., Prüfer, K., Siebauer, M., Burbano, H. A., Ronan, M., Rothberg, J. M., Egholm, M., Rudan, P., Brajković, D., Kućan, Ž., Gušić, I., Wikström, M., Laakkonen, L., Kelso, J., Slatkin, M., & Pääbo, S.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2008-08
- Volume
- 134
- Issue
- 3
- Pages
- 416-426
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1973231394
- Cited by
- 599
- References
- 66
- FWCI
- 312.37
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Green, R. E., Malaspinas, A.-S., Krause, J., Briggs, A. W., Johnson, P. L. F., Uhler, C., Meyer, M., Good, J. M., Maricic, T., Stenzel, U., Prüfer, K., Siebauer, M., Burbano, H. A., Ronan, M., Rothberg, J. M., Egholm, M., Rudan, P., Brajković, D., Kućan, Ž., . . . Pääbo, S. (2008). A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing. Cell. https://doi.org/10.1016/j.cell.2008.06.021
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