CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Majeti, Ravindra, Chao, Mark P., Alizadeh, Ash A., Pang, Wendy W., Jaiswal, Siddhartha, Gibbs, Kenneth D., van Rooijen, Nico, Weissman, Irving L.·2009·Cell

DOI 10.1016/j.cell.2009.05.045

Cited by (1,001)

Items 101–200 of 1,001

Therapeutic targeting of acute myeloid leukemia stem cells
Daniel Aaron Pollyea, Craig T. Jordan · 2017 · Blood
Macrophages are critical effectors of antibody therapies for cancer
Kipp Weiskopf, Irving L. Weissman · 2015 · mAbs
Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal
Mingen Liu, Roddy S. O’Connor, Sophie Trefely, Kathleen L. Graham, Nathaniel W. Snyder, Gregory Lawrence Beatty · 2019 · Nature Immunology
Recent advances in targeted therapies in acute myeloid leukemia
Rahul S. Bhansali, Keith William Pratz, Catherine Lai · 2023 · Journal of Hematology & Oncology
Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy
Bin Bao, Aamir Ahmad, Asfar Sohail Azmi, Shadan S. Ali, Fazlul H. Sarkar · 2013 · Current Protocols in Pharmacology
SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin
Jun Chen, Ming‐Chao Zhong, Huaijian Guo, Dominique Davidson, Sabrin Mishel, Yan Lü, Inmoo Rhee, Luis‐Alberto Pérez‐Quintero, Shaohua Zhang, Mario‐Ernesto Cruz‐Munoz et al. · 2017 · Nature
Emerging phagocytosis checkpoints in cancer immunotherapy
Yue Liu, Yanjin Wang, Yanrong Yang, Linjun Weng, Qi Wu, Jin Zhang, Pengcheng Zhao, Lan Fang, Yufeng Shi, Ping Wang · 2023 · Signal Transduction and Targeted Therapy
WNT Signaling in Tumors: The Way to Evade Drugs and Immunity
E. Martín-Orozco, Ana Sánchez-Fernández, Irene Ortiz-Parra, Maria Ayala-San Nicolas · 2019 · Frontiers in Immunology
Activating Macrophage‐Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles
Lang Rao, Shukun Zhao, Churan Wen, Rui Tian, Lisen Lin, Bo Cai, Yue Sun, Fei Kang, Zhèn Yáng, Liangcan He et al. · 2020 · Advanced Materials
TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding
Penka S. Petrova, Natasja Nielsen Viller, Mark Wong, Xinli Pang, Gloria H. Y. Lin, Karen Dodge, Vien Chai, Hui Chen, Vivian Lee, Violetta House et al. · 2016 · Clinical Cancer Research
Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy
Zhongjian Xie, Minhua Peng, Ruitao Lu, Xiangying Meng, Weiyuan Liang, Zhongjun Li, Meng Qiu, Bin Zhang, Guohui Nie, Ni Xie et al. · 2020 · Light Science & Applications
Therapies targeting cancer stem cells: Current trends and future challenges
Denisa Dragu · 2015 · World Journal of Stem Cells
Microfluidic Sonication To Assemble Exosome Membrane-Coated Nanoparticles for Immune Evasion-Mediated Targeting
Chao Liu, Wei Zhang, Yike Li, Jianqiao Chang, Fei Tian, Fanghao Zhao, Yao Ma, Jiashu Sun · 2019 · Nano Letters
Functions of Immune Checkpoint Molecules Beyond Immune Evasion
Yaping Zhang, Junke Zheng · 2020 · Advances in experimental medicine and biology
Recent Advances in Nanocarrier-Assisted Therapeutics Delivery Systems
Shi Su, Peter M. Kang · 2020 · Pharmaceutics
Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts
Yuchen Wang, Hao Zhang, Chao Liu, Zeyu Wang, Wantao Wu, Nan Zhang, Longbo Zhang, Jason J. Hu, Peng Luo, Jian Zhang et al. · 2022 · Journal of Hematology & Oncology
Leukemic stem cells and therapy resistance in acute myeloid leukemia
Patrick Stelmach, Andreas Trumpp · 2023 · Haematologica
Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma
Edris, Badreddin, Weiskopf, Kipp, Volkmer, Anne K., Volkmer, Jens-Peter, Willingham, Stephen B., Contreras-Trujillo, Humberto, Liu, Jie, Majeti, Ravindra, West, Robert B., Fletcher, Jonathan A. et al. · 2012 · Proceedings of the National Academy of Sciences
Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia
Francesco Buccisano, Luca Maurillo, Maria Ilaria Del Principe, Giovanni Del Poeta, Giuseppe Sconocchia, Francesco Lo‐Coco, William Arcese, Sergio Amadori, Adriano Venditti · 2011 · Blood
Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies
Mark Ping Chao, Chris H.M. Takimoto, Dong Dong Feng, Kelly Marie McKenna, Phung Gip, Jie Liu, Jens-Peter Volkmer, Irving L. Weissman, Ravindra Majeti · 2020 · Frontiers in Oncology
Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk
Mingye Feng, James Y. Chen, Rachel Weissman-Tsukamoto, Jens-Peter Volkmer, Po Yi Ho, Kelly Marie McKenna, Samuel Henry Cheshier, Michael Zhang, Nan Guo Ring, Phung Gip et al. · 2015 · Proceedings of the National Academy of Sciences
CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis
Meghan A. Morrissey, Nadja Kern, Ronald D. Vale · 2020 · Immunity
Cancer stem cells – important players in tumor therapy resistance
Selçuk Çolak, Jan Paul Medema · 2014 · FEBS Journal
Cancer Stemness Meets Immunity: From Mechanism to Therapy
Peiwen Chen, Wen‐Hao Hsu, Jincheng Han, Yan Xia, Ronald Anthony DePinho · 2021 · Cell Reports
Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells
Dongkyoon Kim, Jian Wang, Stephen B. Willingham, R.K. Martin, Gerlinde Wernig, Irving L. Weissman · 2012 · Leukemia
Programmed cell removal: a new obstacle in the road to developing cancer
Mark Ping Chao, Ravindra Majeti, Irving L. Weissman · 2011 · Nature reviews. Cancer
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity
Christina A. Von Roemeling, Yifan Wang, Yaqing Qie, Hengfeng Yuan, Zhao Hai, Xiujie Liu, Zhaogang Yang, Mingming Yang, Weiye Deng, Katelyn A. Bruno et al. · 2020 · Nature Communications
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy
Meike E. W. Logtenberg, J.H. Marco Jansen, Matthijs Raaben, Mireille Toebes, Katka Franke, Arianne M. Brandsma, Hanke L. Matlung, Astrid Fauster, Raquel Gomez, Noor A. M. Bakker et al. · 2019 · Nature Medicine
Macrophages as mediators of tumor immunosurveillance
Siddhartha Jaiswal, Mark Ping Chao, Ravindra Majeti, Irving L. Weissman · 2010 · Trends in Immunology
Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis
Mingyue Li, Lizhong Liu, Ming Dong · 2021 · Molecular Cancer
Cell membrane coated-nanoparticles for cancer immunotherapy
Zeng, Yingping, Li, Sufen, Zhang, Shufen, Wang, Li, Yuan, Hong, Hu, Fuqiang · 2022 · Acta Pharmaceutica Sinica B
Camouflage strategies for therapeutic exosomes evasion from phagocytosis
Nicol Parada, Alfonso Romero-Trujillo, Nicolás Georges, Francisca Alcayaga‐Miranda · 2021 · Journal of Advanced Research
CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease
Per‐Arne Oldenborg · 2013 · ISRN Hematology
Catch me if you can: how AML and its niche escape immunotherapy
Sarah Tettamanti, Alice Pievani, Andrea Biondi, Gianpietro Dotti, Marta Serafini · 2021 · Leukemia
Exploiting innate immunity for cancer immunotherapy
Ming Yi, Tianye Li, Mengke Niu, Qi Mei, Bin Zhao, Qian Chu, Zhijun Dai, Kongming Wu · 2023 · Molecular Cancer
SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells
Li, Ling, Osdal, Tereza, Ho, Yinwei, Chun, Sookhee, McDonald, Tinisha, Agarwal, Puneet, Lin, Allen, Chu, Su, Qi, Jing, Li, Liang et al. · 2014 · Cell stem cell
Crosstalk between ER stress and immunogenic cell death
Oliver Kepp, Laurie Menger, Erika Vacchelli, Clara Locher, Sandy Adjemian, Takahiro Yamazaki, Isabelle Martins, Abdul Qader Sukkurwala, Michael Michaud, Laura Senovilla et al. · 2013 · Cytokine & Growth Factor Reviews
Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.
Tzu-Chieh Ho, M. LaMere, Brett M. Stevens, J. Ashton, Jason R. Myers, K. O'Dwyer, J. Liesveld, Jason H. Mendler, M. Guzman, Jennifer J. D. Morrissette et al. · 2013 · Blood
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms
Michele Cioffi, Sara Maria David Trabulo, Manuel M. Hidalgo, Eithne Costello, William Greenhalf, Mert Erkan, Jorg H. Kleeff, Bruno Sáinz, Christopher Heeschen · 2015 · Clinical Cancer Research
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53
Kyoung Wan Yoon, Sanguine Byun, Eun‐Jeong Kwon, So-Young Hwang, Kiki Chu, Masatsugu Hiraki, Seung‐Hee Jo, Astrid Weins, Samy Hakroush, Angelika Cebulla et al. · 2015 · Science
Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 “Don't Eat Me” Signals
Melissa N. McCracken, Adriel C. Cha, Irving L. Weissman · 2015 · Clinical Cancer Research
Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy
Jenna L. Carter, Katie Hege-Hurrish, Jay Yang, Hasini A. Kalpage, Yongwei Su, Holly J. Edwards, Maik Hüttemann, Jeffrey Warren Taub, Yubin Ge · 2020 · Signal Transduction and Targeted Therapy
Non-self recognition by monocytes initiates allograft rejection
Martin H. Oberbarnscheidt, Qiang Zeng, Qi Li, Hehua Dai, Amanda L. Williams, Warren D. Shlomchik, David M. Rothstein, Fadi G. Lakkis · 2014 · Journal of Clinical Investigation
Nanoparticle‐based photothermal and photodynamic immunotherapy for tumor treatment
Xiaoyang Hou, Yingkai Tao, Yanyu Pang, Xinxin Li, Guan Jiang, Yanqun Liu · 2018 · International Journal of Cancer
CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell–Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1
Yunqin Lee, June Ho Shin, Michelle R. Longmire, Hua Wang, Holbrook E K Kohrt, Howard Y. Chang, John B. Sunwoo · 2016 · Clinical Cancer Research
Leukemic Stem Cell Frequency: A Strong Biomarker for Clinical Outcome in Acute Myeloid Leukemia
Monique Terwijn, Wendelien Zeijlemaker, Angèle Kelder, Arjo P. Rutten, Alexander N. Snel, Willemijn J. Scholten, Thomas Pabst, Gregor E. G. Verhoef, Bob Löwenberg, Sonja Zweegman et al. · 2014 · PLoS ONE
Macrophage targeting in cancer
Martha Lopez‐Yrigoyen, Luca Cassetta, Jeffrey W. Pollard · 2020 · Annals of the New York Academy of Sciences
Advancing to the era of cancer immunotherapy
Yun Wang, Min Wang, Hao‐Xiang Wu, Rui‐Hua Xu · 2021 · 癌症：英文版
Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges
Muhammad Zaeem Noman, Meriem Hasmim, Audrey Lequeux, Malina Xiao, Caroline Duhem, Salem Chouaı̈b, Guy Berchem, Bassam Janji · 2019 · Cells
Blockade of Cd47-Mediated Cathepsin S/Protease-Activated Receptor 2 Signaling Provides a Therapeutic Target for Hepatocellular Carcinoma
Terence K. Lee, Vincent Chi Ho Cheung, Ping Lu, Eunice Yuen-Ting Lau, Stephanie Ma, Kwan Ho Tang, Man Tong, Jessica Hiu Tung Lo, Irene Oi‐Lin Ng · 2014 · Hepatology
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
Caroline Pabst, Anne Bergeron, Vincent‐Philippe Lavallée, Jonathan R. Yeh, Patrick Gendron, Gudmundur Logi Norddahl, Jana Krošl, Isabel Boivin, Éric Deneault, J. J. L. Simard et al. · 2016 · Blood
Sialoglycans and Siglecs Can Shape the Tumor Immune Microenvironment
Stephanie van de Wall, Kim C. M. Santegoets, Eline J.H. van Houtum, Christian Büll, Gosse J. Adema · 2020 · Trends in Immunology
Engineered Bacterial Outer Membrane Vesicles as Controllable Two‐Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy
Qingqing Feng, Xiaotu Ma, Keman Cheng, Guangna Liu, Yao Li, Yale Yue, Jie Liang, Lizhuo Zhang, Tianjiao Zhang, Xinwei Wang et al. · 2022 · Advanced Materials
Human Cancer Growth and Therapy in Immunodeficient Mouse Models
Leonard D. Shultz, Neal C. Goodwin, Fumihiko Ishikawa, Vishnu Hosur, Bonnie L. Lyons, Dale L. Greiner · 2014 · Cold Spring Harbor Protocols
Monocytes and Macrophages in Cancer: Development and Functions
David M. Richards, Jan Hettinger, Markus Feuerer · 2012 · Cancer Microenvironment
Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents
Carsten Riether, Thomas Pabst, Sabine Höpner, Ulrike Bacher, Magdalena Hinterbrandner, Yara Banz, Rouven Müller, Markus Gabriel Manz, Walid H. Gharib, David Miguel Ferreira Francisco et al. · 2020 · Nature Medicine
The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
Samantha S.W. Ho, Wendy Y.L. Zhang, Nikki Y. Tan, Muznah Khatoo, Manuel Adrian Suter, Shubhita Tripathi, Florence S.G. Cheung, Weng Khong Lim, Puay Hoon Tan, Joanne Yuen Yie Ngeow et al. · 2016 · Immunity
CD47/SIRPα pathway mediates cancer immune escape and immunotherapy
Xiao Jia, Bingjun Yan, Xiaoqing Tian, Qian Liu, Jianhua Jin, Juanjuan Shi, Yongzhong Hou · 2021 · International Journal of Biological Sciences
Calreticulin in the immune system: ins and outs
Malini Raghavan, Sanjeeva Joseph Wijeyesakere, Larry Robert Peters, Natasha Del Cid · 2012 · Trends in Immunology
Neutrophils in cancer
Louise W. Treffers, Ida H. Hiemstra, Taco Willem Kuijpers, Timo K. van den Berg, Hanke L. Matlung · 2016 · Immunological Reviews
CD47: role in the immune system and application to cancer therapy
Seyed Mohammad Gheibi Hayat, Vanessa Bianconi, Matteo Pirro, Mahmoud Reza Jaafari, Mahdi Hatamipour, Amirhossein Sahebkar · 2019 · Cellular Oncology
Phase I Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies
Stephen Maxted Ansell, Michael B. Maris, Alexander M. Lesokhin, Robert W. Chen, Ian W. Flinn, Ahmed Sawas, Mark David Minden, Diego R. Villa, Mary‐Elizabeth M. Percival, Anjali S. Advani et al. · 2021 · Clinical Cancer Research
Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS
Barreyro, Laura, Will, Britta, Bartholdy, Boris, Zhou, Li, Todorova, Tihomira I., Stanley, Robert F., Ben-Neriah, Susana, Montagna, Cristina, Parekh, Samir, Pellagatti, Andrea et al. · 2012 · Blood
CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia
Jinghua Wang, Siyu Chen, Wei Xiao, Wende Li, Liang Wang, Shuo Yang, Weida Wang, Liping Xu, Shuangye Liao, Wenjian Liu et al. · 2018 · Journal of Hematology & Oncology
Nuclear factor kappa B–mediated CD47 up‐regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice
Jessica Hiu Tung Lo, Eunice Yuen-Ting Lau, Rachel Hiu Ha Ching, Bowie Yik-Ling Cheng, Mark Kin Fai Ma, Irene Oi‐Lin Ng, Terence K. Lee · 2015 · Hepatology
Phosphatidylserine: A cancer cell targeting biomarker
Bhupender Sharma, Shamsher S. Kanwar · 2017 · Seminars in Cancer Biology
Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy
Mark Ping Chao, Chad Z. Tang, Russell Kent Pachynski, Robert Chin, Ravindra Majeti, Irving L. Weissman · 2011 · Blood
Regulatory cells and the effect of cancer immunotherapy
María Iglesias-Escudero, Noelia Arias-González, Eva María Martínez-Cáceres · 2023 · Molecular Cancer
A comprehensive review of immune checkpoint inhibitors for cancer treatment
Md Aslam Hossain · 2024 · International Immunopharmacology
CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
David R. Soto‐Pantoja, Masaki Terabe, Arunima Ghosh, Lisa A. Ridnour, William DeGraff, David A. Wink, Jay A. Berzofsky, David D. Roberts · 2014 · Cancer Research
Chemotherapy and radiotherapy: Cryptic anticancer vaccines
Yuting Ma, Oliver Kepp, François Ghiringhelli, Lionel Apétoh, Laetitia Aymeric, Clara Locher, Antoine Tesnière, Isabelle Martins, André Ly, Nicole M. Haynes et al. · 2010 · Seminars in Immunology
Blocking “don't eat me” signal of CD47-SIRPα in hematological malignancies, an in-depth review
Atlantis Dawn Russ, Anh Hua, W.R. Montfort, Bushra Rahman, Irbaz Bin Riaz, Muhammad Umar Khalid, Jennifer S. Carew, Steffan T. Nawrocki, Daniel Oscar Persky, Faiz Anwer · 2018 · Blood Reviews
Targeting breast cancer stem cells
Sean McDermott, Max S. Wicha · 2010 · Molecular Oncology
Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis
Yuhua Wang, Zhenghong Xu, Shutao Guo, Lu Zhang, Arati K. Sharma, Gavin P. Robertson, Leaf Huang · 2013 · Molecular Therapy
Magrolimab in Combination With Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes: Final Results of a Phase Ib Study
Sallman, David A., Al Malki, Monzr M., Asch, Adam S., Wang, Eunice S., Jurcic, Joseph G., Bradley, Terrence J., Flinn, Ian W., Pollyea, Daniel A., Kambhampati, Suman, Tanaka, Tiffany N. et al. · 2023 · Journal of Clinical Oncology
Is CD47 an innate immune checkpoint for tumor evasion?
Xiaojuan Liu, Hyunwoo Kwon, Zihai Li, Yang‐Xin Fu · 2017 · Journal of Hematology & Oncology
Engulfment signals and the phagocytic machinery for apoptotic cell clearance
Seung‐Yoon Park, In‐San Kim · 2017 · Experimental & Molecular Medicine
In-Depth Characterization of Monocyte-Derived Macrophages using a Mass Cytometry-Based Phagocytosis Assay
Daniel Schulz, Yannik Severin, Vito RT Zanotelli, Bernd Bodenmiller · 2019 · Scientific Reports
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein
Marcus Järås, Petra Johnels, Nils Hansen, Helena Ågerstam, Panagiotis Tsapogas, Marianne Rissler, Carin Lassen, Tor Olofsson, Ole Weis Bjerrum, Johan Richter et al. · 2010 · Proceedings of the National Academy of Sciences
Nanobody-based CAR-T cells for cancer immunotherapy
Pouya Safarzadeh Kozani, Abdolhossein Naseri, Seyed Mohamad Javad Mirarefin, Faeze Salem, Mojtaba Nikbakht, Sahar Evazi Bakhshi, Pooria Safarzadeh Kozani · 2022 · Biomarker Research
Increased Oxidative Stress as a Selective Anticancer Therapy
Jiahui Liu, Zhichong Wang · 2015 · Oxidative Medicine and Cellular Longevity
Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach
Hagop M. Kantarjian, Tapan Mahendra Kadia, Courtney Denton Dinardo, Mary Alma Welch, Farhad Ravandi · 2021 · Cancer
Macrophages Associated with Tumors as Potential Targets and Therapeutic Intermediates
Serguei V. Vinogradov, Galya Warren, Xin Wei · 2014 · Nanomedicine
Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas
Amanda R. Dancsok, Dongxia Gao, Anna F. Lee, Sonja Eriksson Steigen, Jean‐Yves Blay, David Morgan Thomas, Robert G. Maki, Torsten O. Nielsen, Elizabeth G. Demicco · 2020 · OncoImmunology
Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis
Masayuki Yamashita, Paul V. Dellorusso, Oakley C. Olson, Emmanuelle A. Passegue · 2020 · Nature reviews. Cancer
The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation
Maaike Schilperoort, David Ngai, Santosh Reddy Sukka, Kleopatra Avrampou, Hongxue Shi, Ira A. Tabas · 2023 · Immunological Reviews
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Paul A. Bunn, John Dorrance Minna, Alexander Augustyn, Adi F. Gazdar, Youcef Ouadah, Mark A. Krasnow, Anton J. M. Berns, Elisabeth M. Brambilla, Natasha Rekhtman, Pierre P. Massion et al. · 2016 · Journal of Thoracic Oncology
Functions of Thrombospondin-1 in the Tumor Microenvironment
Sukhbir Kaur, Steven M. Bronson, Dipasmita Pal-Nath, Thomas W. Miller, David R. Soto‐Pantoja, David D. Roberts · 2021 · International Journal of Molecular Sciences
Humanized mouse model supports development, function, and tissue residency of human natural killer cells
Dietmar Herndler‐Brandstetter, Liang Shan, Yi Yao, Carmen Stecher, Valerie Plajer, Melanie Lietzenmayer, Till Strowig, Marcel R. de Zoete, Noah W. Palm, Jie Chen et al. · 2017 · Proceedings of the National Academy of Sciences
Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer
Yu Pan, Fengchun Lu, Qinglin Fei, Xingxing Yu, Ping Xiong, Xunbin Yu, Yuan Dang, Zelin Hou, Wenji Lin, Xianchao Lin et al. · 2019 · Journal of Hematology & Oncology
CD47 signaling pathways controlling cellular differentiation and responses to stress
David R. Soto‐Pantoja, Sukhbir Kaur, David D. Roberts · 2015 · Critical Reviews in Biochemistry and Molecular Biology
CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest
Émilie Sick, Albin Jeanne, Christophe Schneider, Stéphane Dedieu, Kenneth Takeda, Laurent Martiny · 2012 · British Journal of Pharmacology
Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment
Bo Wu, Xiang Shi, Meixi Jiang, Hongxu Liu · 2023 · Molecular Cancer
Targeting macrophages in hematological malignancies: recent advances and future directions
Wei Li, Fang Wang, Rongqun Guo, Zhilei Bian, Yongping Song · 2022 · Journal of Hematology & Oncology
The CD47-SIRP signalling system: its physiological roles and therapeutic application
Yoji Murata, Takenori Kotani, Hiroshi Ohnishi, Takashi Matozaki · 2014 · The Journal of Biochemistry
Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy
Akanksha Chhabra, Aaron M. Ring, Kipp Weiskopf, Peter John Schnorr, Sydney R. Gordon, Alan Le, Hye-Sook Kwon, Nan Guo Ring, Jens P. Volkmer, Po Yi Ho et al. · 2016 · Science Translational Medicine
A rapid, automated surface protein profiling of single circulating exosomes in human blood
Golam Kibria, Erika K. Ramos, Katelyn E. Lee, Sarah Bedoyan, Simo Huang, Ravand Samaeekia, Jaffre J. Athman, Clifford V. Harding, Jan O. Lötvall, Lyndsay N. Harris et al. · 2016 · Scientific Reports
The clinical impact of the molecular landscape of acute myeloid leukemia
Sabine Käyser, Mark J. Levis · 2023 · Haematologica
Breast cancer stem cells: Multiple capacities in tumor metastasis
Shaoqing Geng, Aris T. Alexandrou, Jian Jian Li · 2014 · Cancer Letters
ALX148 blocks CD47 and enhances innate and adaptive antitumor immunity with a favorable safety profile
Steven E. Kauder, Tracy C. Kuo, Ons Harrabi, Amy Yen-Chi Chen, Emma Sangalang, Laura V. Doyle, Sony Sotelo Rocha, Sangeetha Subbarao Bollini, Bora Han, Janet Sim et al. · 2018 · PLoS ONE