EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

Cited by (255)

Items 201–255 of 255

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  6. Activity-dependent regulation of Cdc42 by Ephexin5 drives synapse growth and stabilization
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    Garrett A. Kaas, Kimberly E. Hawkins, J. David Sweatt · 2017 · Elsevier eBooks
  9. Angelman Syndrome causing UBE3A ligase displays predominantly synaptic ubiquitination activity in the mouse brain
    Ugo Mayor, Unai Alduntzin, Benoit Louis Philippe Lectez, Natalia Presa, Nerea Osinalde, Marta Fernandez, Nagore Elu, Juanma Ramírez, Cristina Garcia-Barcena, Kerman Aloria et al. · 2023 · Research Square
  10. Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    Chao Chang, Sara L. Banerjee, Sung Soon Park, Xiaolei Zhang, David Cotnoir‐White, Karla J. Opperman, Muriel Desbois, Brock J. Grill, Artur Kania · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids
    R. Chris Estridge, Z. Begum Yagci, Dilara Sen, Travis Ptacek, Jeremy M. Simon, Albert J. Keung · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Emerging Research towards the Understanding and Treatment of Autism
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  13. E3 ubiquitin ligases and cerebral cortex development in health and disease
    Nicolas Lambert, Martin Moïse, Laurent Nguyen · 2022 · Developmental Neurobiology
  14. RNAi-Induced Expression of Paternal UBE3A
    Hye Ri Kang, Violeta Zaric, Volodymyr Rybalchenko, Steven J. Gray, Ryan K. Butler · 2026 · Genes
  15. Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
    Chrysanthi‐Maria Moysidou, Inês B. Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara-Camelia Rusu, Aylin Nebol, Ines Lahmann et al. · 2026 · Advanced Science
  16. Principles Driving the Spatial Organization of Rho GTPase Signaling at Synapses
    Scott H. Soderling, Linda Van Aelst · 2014 · Springer eBooks
  17. RhoGEF Tiam2 Regulates Glutamatergic Synaptic Transmission in Hippocampal CA1 Pyramidal Neurons
    Sadhna Rao, Feng Liang, Bruce E. Herring · 2024 · eNeuro
  18. Ubiquitin ligase signalling networks shape presynaptic development, function and disease
    Melissa A. Borgen, Brock J. Grill · 2024 · The Journal of Physiology
  19. Differences in structure, dynamics, and zinc coordination between isoforms of human ubiquitin ligase UBE3A
    Thomas A. Bregnard, Daniel Fairchild, Xiang Chen, Heidi Erlandsen, Sergey G. Tarasov, Kylie J. Walters, Dmitry M. Korzhnev, Irina Bezsonova · 2024 · Journal of Biological Chemistry
  20. Transcriptomic Profiling of Mice Primary Cortical Neurons in Response to Medium Change
    Juan Andres Rubiolo, Carmen Vale, Victor Martín, Aida G. Méndez, Andrea Boente-Juncal, Mercedes R. Vieytes, Luis Miguel Botana · 2016 · Transcriptomics Open Access
  21. Therapeutic Approaches to Imprinting Diseases
    Hiromitsu Hattori, Hitoshi Hiura, Norio Kobayashi, Souta Takahashi, Hiroaki Okae, Takahiro Arima · 2018 · Elsevier eBooks
  22. Scaffold Protein Lnx1 Stabilizes EphB Receptor Kinases for Synaptogenesis
    Na Li, Si Chen, Nan‐Jie Xu, Suya Sun, Jinjin Chen, Xiandong Liu · 2022 · Frontiers in Molecular Neuroscience
  23. E3 Ubiquitin Ligases as Molecular Machines and Platforms for Drug Development
    Rafael M. Ioris, Katherine Ferris, Vincenzo D’Angiolella · 2022 · Wiley eBooks
  24. Guided maturation of human neuromuscular organoids via electrical stimulation
    Chrysanthi‐Maria Moysidou, Inês B. Martins, Ismail Amr El‐Shimy, Donatella Cea, Christina Bukas, Isra Mekki, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Ube3a Role in Synaptic Plasticity and Neurodevelopmental Disorders.The Lessons from Angelman Syndrome.
    Irina Filonova · 2014 · Digital Commons - University of South Florida (University of South Florida)
  26. Intercellular communication in cortical neuronal elaboration and circuit formation: A role for EphA signaling
    Meredith A. Clifford · 2012 · Georgetown University-Graduate School of Arts & Sciences
  27. Minocycline Treatment and the Necessity to Develop a Novel Outcome Measure for Children with Angelman Syndrome
    Joseph C. Grieco · 2015 · Digital Commons - University of South Florida (University of South Florida)
  28. The role of E3 ubiquitin ligase FBXO31-SCF in neuronal morphogenesis
    Mayur Vadhvani · 2013 · eDiss (Georg-August-Universität Göttingen)
  29. A Chemical-Genetic Study of EphB Receptor Tyrosine Kinase Signaling in the Developing Nervous System
    Michael J. Soskis · 2012 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  30. Ephrin B3 (EphB3) receptors expressed in spinal tissue of rats with spinal cord injury
    Xiaodong Zhi · 2012 · African Journal of Pharmacy and Pharmacology
  31. A 15q11–q13 Duplication Mouse Model of Autism Spectrum Disorders
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  32. Imprinting in the CNS and Neurodevelopmental Disorders
    Weston T. Powell, Janine M. LaSalle · 2013 · Elsevier eBooks
  33. rEviSÃo DE litEratUra A patogênese genética e molecular da síndrome de Angelman The genetic and molecular pathogenesis of the Angelman syndrome
    Angélica Francesca Maris, Alexis Trott, Síndrome de Angelman · 2011
  34. Effects of Localized EphB2 Stimulation on Dendritic Filopodia of Hippocampal Neurons
    Clifford Locke · 2018 · OpenCommons at University of Connecticut (University of Connecticut)
  35. Disrupted synaptic transmission and abnormal short-term synaptic plasticity in an Angelman syndrome mouse model
    Guohui Li · 2017
  36. Regulation of Dendritic Spine Development and Cell Migration through Asef2-mediated Signaling
    J. Corey Evans · 2014
  37. The Effect of ARHGEF15 Knockout and Forebrain-Specific Human ARHGEF15 Knock-In on Seizure Susceptibility in Mice
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    Kwok‐On Lai, Nancy Y. Ip · 2012 · Springer eBooks
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  46. Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    Chao Chang, Sara L. Banerjee, Sung Soon Park, Xiaolei Zhang, David Cotnoir‐White, Muriel Desbois, Brock J. Grill, Artur Kania · 2023 · eLife
  47. Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    Chao Chang, Sara L. Banerjee, Sung Soon Park, Xiaolei Zhang, David Cotnoir‐White, Muriel Desbois, Brock J. Grill, Artur Kania · 2023 · eLife
  48. Therapeutic approaches to imprinting diseases
    Hela Sassi, Léa Guerrini‐Rousseau, Jacques Grill, Étienne Rouleau · 2023 · Elsevier eBooks
  49. Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    Chao Chang, Sara L. Banerjee, Sung Soon Park, Xiaolei Zhang, David Cotnoir‐White, Karla J. Opperman, Muriel Desbois, Brock J. Grill, Artur Kania · 2023 · eLife
  50. Dysregulation of Neuronal Activity‐Dependent Immediate Early Genes in a Mouse Model of Angelman Syndrome
    Bhaskarjyoti Giri, Sagarika Das, Sudipta Jana, Nihar Ranjan Jana · 2025 · Journal of Neurochemistry
  51. Phenotyping iPSC-derived neurons from Angelman patients and partial rescue via JNK pathway inactivation
    Valentina Alari, Clara Cambria, Chiara De Cesari, Alessandro Vimercati, M. Crippa, Sara Perego, Lidia Larizza, Ilaria Tonazzini, Flavia Antonucci, Silvia Russo · 2026 · Journal of Neurodevelopmental Disorders
  52. Members of the RhoA subfamily of GTPases suppress the stimulatory effect of the HPV E6 oncoprotein on the ubiquitin ligase E6AP
    Daniela Eichbichler, Jasmin Jansen, Nadja Eulich, Florian Stengel, Martin Scheffner · 2026 · Scientific Reports
  53. RhoA/ROCK signaling as a potential convergent pathway in microbiota–gut–brain axis-related cognitive impairment
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  54. Aberrant accumulation of α-synuclein might be linked with the progressive motor deficits in a mouse model of Angelman syndrome
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  55. Impaired Kv4.2-DPP6 complex dynamics in a mouse model of Angelman syndrome
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