Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones
Dutchak, Paul A., Katafuchi, Takeshi, Bookout, Angie L., Choi, Jang Hyun, Yu, Ruth T., Mangelsdorf, David J., Kliewer, Steven A.·2012·Cell
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- Behavioral, Hormonal, Inflammatory, and Metabolic Effects Associated with FGF21-Pathway Activation in an ALS Mouse ModelJean-Baptiste Delaye, Débora Lanznaster, Charlotte Veyrat‐Durebex, Alix Fontaine, Guillaume Bacle, Antoine Lefèvre, Rudolph Hergesheimer, Jean‐Claude Lecron, Patrick Vourc’h, Christian Robert Andres et al. · 2020 · Neurotherapeutics
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- Skeletal integration of energy homeostasis: Translational implicationsBeata Lecka‐Czernik, Clifford james Rosen · 2015 · Bone
- Effects of pioglitazone and fenofibrate co-administration on bone biomechanics and histomorphometry in ovariectomized ratsSusan Y. Smith, Rana Samadfam, Luc Chouinard, Malaika Awori, Agnes M. Benardeau, Frieder Bauss, Robert E. Guldberg, ELENA ŠEBÖKOVÁ, Matthew B. Wright · 2014 · Journal of Bone and Mineral Metabolism
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- Gender differences in non-glycemic responses to improved insulin sensitivity by pioglitazone treatment in patients with type 2 diabetesLisa Arnetz, Mozhgan Dorkhan, Michael Alvarsson, Kerstin Brismar, Neda Rajamand Ekberg · 2013 · Acta Diabetologica
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- Metabolic Regulation by Nuclear ReceptorsSihao Liu, Michael Downes, Ronald M. Evans · 2015 · Springer eBooks
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- Fibroblast growth factor 21, adiposity, and macronutrient balance in a healthy, pregnant population with overweight and obesityElizabeth F. Sutton, Christopher D. Morrison, Jacqueline M. Stephens, Leanne Maree Redman · 2018 · Endocrine Research
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- Advances in FGFs for diabetes care applicationsYinai Liu, Qianqian Chen, Yaoqi Li, Liuliu Bi, Zhiying He, Chuxiao Shao, Libo Jin, Renyi Peng, Xingxing Zhang · 2022 · Life Sciences
- The New Markers of Early Obesity-Related Organ and Metabolic AbnormalitiesAgata Ziomber-Lisiak, Kaja Piana, Beata Ostachowicz, Paweł Wróbel, Paula Kasprzyk, Jolanta Kaszuba-Zwoińska, Agnieszka Baranowska-Chowaniec, Kajetan Juszczak, Magdalena Szczerbowska‐Boruchowska · 2022 · International Journal of Molecular Sciences
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- The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in miceSylvie Casteras, Aya Abdul-Wahed, Maud Soty, Fanny Vulin, Hervé Guillou, Maria B. Campaña, Hervé Le Stunff, Luciano Pirola, Fabienne Rajas, Gilles Mithieux et al. · 2016 · Diabetologia
- The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicityJingmin Zhu, Xiao Hua Huang, Hui Jiang, Lingling Hu, Jennifer J. Michal, Zhihua Jiang, Huahong Shi · 2018 · The Science of The Total Environment
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