A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility
Bassik, Michael C., Kampmann, Martin, Lebbink, Robert Jan, Wang, Shuyi, Hein, Marco Y., Poser, Ina, Weibezahn, Jimena, Horlbeck, Max A. +6 more·2013·Cell
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- Relationship between the Expression Level of PSMD11 and Other Proteasome Proteins with the Activity of Ricin and ViscuminDiana V. Maltseva, M. P. Raigorodskaya, Olga V. Tikhonova, Evgeny N. Knyazev, E. A. Tonevitsky · 2020 · Doklady Biochemistry and Biophysics
- Mammalian genes interactingNicole Rusk · 2013 · Nature Methods
- Intracellular Transport of Ribosome-Inactivating Proteins Depends on Annexin 13Diana V. Maltseva, M. P. Raigorodskaya, Victor Gavrilovich Zgoda, E. A. Tonevitsky, Evgeny N. Knyazev · 2020 · Doklady Biochemistry and Biophysics
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- A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial FissionJessica Lee, Zachary Pappalardo, Deeksha Gambhir, Thomas G. Hennings, Ian W. Vaughn, Christopher Lan, Justin Choe, Kenny Ang, Steven Chen, Michelle R. Arkin et al. · 2018 · Endocrinology
- Methods for genetic analysis of mammalian ER-associated degradationDara E. Leto, Ron R. Kopito · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
- Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide ScreenClaire Simonneau, Junning Yang, Xianguo Kong, Robert Kilker, Leonard C. Edelstein, Paolo M. Fortina, Eric R. Londin, Arie Horowitz · 2019 · Scientific Reports
- Differences in Medium-Induced Conformational Plasticity Presumably Underlie Different Cytotoxic Activity of Ricin and ViscuminPavel E. Volynsky, Diana V. Maltseva, Valentin М. Tabakmakher, Eduard Valeryevich Bocharov, M. P. Raigorodskaya, Г. С. Захарова, Elena V. Britikova, Alexander Tonevitsky, Roman G. Efremov · 2022 · Biomolecules
- Parallel genome-wide CRISPR analysis identifies a role for heterotypic ubiquitin chains in ER-associated degradationDara E. Leto, David W. Morgens, Lichao Zhang, Christopher Paul Walczak, Joshua Eric Elias, Michael Cory Bassik, Ron R. Kopito · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Minimized combinatorial CRISPR screens identify genetic interactions in autophagyValentina Diehl · 2022
- Faculty Opinions recommendation of CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming.Kazutoshi Takahashi · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Protein Structure and Biology: Poster Abstracts2013 · Prion
- Endocytosis gated by emergent properties of membrane-clathrin interactionsXinxin Wang, Yueping Li, Ailing Liu, Ronnin Padilla, Donghoon M. Lee, Dae‐Hwan Kim, Marcel Mettlen, Zhiming Chen, Sandra L. Schmid, Gaudenz M. Danuser · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Simultaneous single-cell CRISPR, RNA, and ATAC-seq enables multiomic CRISPR screens to identify gene regulatory relationshipsKaivalya Shevade, Yeqing Angela Yang, Kevin Feng, Karl Mader, Volkan Sevi̇m, Jacob Parsons, Gunisha Arora, Hasnaa A. Elfawy, Rachel Mace, Scot Federman et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- A family of lethal exotoxins defined by cell entry via the Attractin receptorRaghuvir Viswanatha, Donghoon Lee, William Paul Robins, Enzo Mameli, Yanhui Hu, Ah‐Ram Kim, Yousuf Hashmi, Hiroshi Nishida, Gyan Prakash, Matthew Butnaru et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Reverse engineering biological networks: computational approaches for modeling biological systems from perturbation dataYungil Kim · 2013 · University of Minnesota Digital Conservancy (University of Minnesota)
- Interaction maps for mammalsHannah Stower · 2013 · Nature Reviews Genetics
- Intracellular trafficking of ricin A chain in relation to its cytotoxicity and depurination in Saccharomyces cerevisiaeQing Yan · 2013
- Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogationSan Francisco, Howard Hughes Medical · 2015
- Mapping genetic interactions across many phenotypes in metazoan cellsChristina Laufer, Maximilian Billmann, Michael Boutros · 2015 · Cambridge University Press eBooks
- BioID indicates the involvement of the TRAPP protein TrappC11 in autophagyQingchuan Zhao · 2016 · Spectrum Research Repository (Concordia University)
- Characterization of TRAPPC11 and GOSR2 mutations in human fibroblastsKeshika Prematilake · 2016 · Spectrum Research Repository (Concordia University)
- Development of a multiplexed RNAi-coupled sensor assay to study neuronal function on the large-scaleAlexander Herholt · 2017
- Cdk1 has a role in phosphorylating TRAMMSari Snounou · 2017 · Spectrum Research Repository (Concordia University)
- Endocitose e transporte intracelular de isoformas da pulchellinaH. H. T. Moreira · 2017
- Genetic Interactions and Complex Human DiseasesWen Wang · 2017 · University of Minnesota Digital Conservancy (University of Minnesota)
- Learning Dags using Multiclass Support Vector MachinesFabio Nikolay, Marius Pesavento · 2018 · IEEE Statistical Signal Processing Workshop (SSP)
- Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide ScreenClaire Simonneau, Junning Yang, Xianguo Kong, Robert Kilker, Leonard C. Edelstein, Paolo M. Fortina, Eric R. Londin, Arie Horowitz · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- A high-content in vivo screen to identify microRNA epistasis in the repopulating mouse liverAdam M. Zahm, Amber W. Wang, Yue Julia Wang, Jonathan Schug, Kirk J. Wangensteen, Klaus H. Kaestner · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Combinatorial Genetic Screening in CancerFadi J. Najm · 2019 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
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- Identification of fitness genes and genotype-specific vulnerabilities using functional genetic screens in human cancer cellsMegha Chandrashekhar · 2018 · TSpace (University of Toronto)
- Systematic screening reveals synergistic interactions that overcome MAPK inhibitor resistance in cancer cellsYu Yu, Minzhen Tao, Libin Xu, Lei Cao, Baoyu Le, Na An, Jilin Dong, Yajie Xu, Baoxing Yang, Wěi Li et al. · 2021 · Cancer Biology and Medicine
- Machine Learning to Identify Gene Interactions from High-Throughput Mutant CrossesAshwani Kumar, Andrew D. S. Cameron, Sandra Zilles · 2021 · Methods in molecular biology
- Characterization of the role of TRAPPC2/Trs20p-related and associated proteins in membrane trafficNassim Shahrzad · 2014 · Spectrum Research Repository (Concordia University)
- Faculty Opinions recommendation of Trans effects on gene expression can drive omnigenic inheritance.Melanie Bahlo · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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- Faculty Opinions recommendation of Trans effects on gene expression can drive omnigenic inheritance.Murray Stewart · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.Qiang Pan‐Hammarström, Bo Zhang · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.Roderic Guigó · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Supplementary Data from Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and SusceptibilitiesMarcus R. Kelly, Kaja Kostyrko, Kyuho Han, Nancie A. Mooney, Edwin E. Jeng, Kaitlyn K. Spees, Phuong Dinh, Keene L. Abbott, Dana M. Gwinn, Alejandro Sweet-Cordero et al. · 2023
- Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER in RenVM neuronsJeremy Changyu Yeo, Felicia P. Tay, Rebecca Bennion, Omar Loss, Jacquie Maignel, Laurent Pons, Keith Foster, Matthew Beard, Frédéric Bard · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- The Arabidopsis thaliana TRAPPIII subunit AtTRAPPC8/AtTRS85 is involved in ER functioning and autophagyMarta Hoffman‐Sommer, Natalia Piłka, Anna Anielska-Mazur, Julita Nowakowska, Yasin Dagdas, Ewa Świeżewska · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER in RenVM neuronsJeremy Changyu Yeo, Felicia P. Tay, Rebecca Bennion, Omar Loss, Jacquie Maignel, Laurent Pons, Keith Foster, Matthew Beard, Frédéric Bard · 2024 · eLife
- An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplantRebecca A. Lee, Deeksha Gambhir, Vinh Q Nguyen, Xi‐Ping Huang, Yaohuan Zhang, Kaavian Shariati, Nicholas Yiv, Rebecca C. Schugar, Justin P. Annes, Bryan L. Roth et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- IGFBP6 Modulates Proteostasis by Activating ATF4 Targets and Reducing ER Retrotranslocon ExpressionO. E. Kolodeeva, O. E. Kolodeeva, Ivan Denisovich Antipenko, Artem Fatkulin, M. R. Yakhina, Julia Alekseevna Makarova · 2024 · Доклады Российской академии наук Науки о жизни
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- Functional Toxicology: Key Concepts and ApplicationsChan Hyeok Kim, Chris D. Vulpe · 2025 · Elsevier eBooks
- Additional file 5 of CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in gliomaLiu, S. John, Martina Malatesta, Brian V. Lien, Parna Saha, Shivani S. Thombare, Hong, Sung Jun, Leslie Pedraza, Koontz, Mark, Kyounghee Seo, Max A. Horlbeck et al. · 2020 · Figshare
- Additional file 2 of Evidence for widespread existence of functional novel and non-canonical human transcriptsDongyang Xu, Tang, Lu, Junjun Zhou, Wang, Fang, Huifen Cao, Huang, Yu, Philipp Kapranov · 2024 · Figshare
- Additional file 1 of Evidence for widespread existence of functional novel and non-canonical human transcriptsDongyang Xu, Tang, Lu, Junjun Zhou, Wang, Fang, Huifen Cao, Huang, Yu, Philipp Kapranov · 2023 · Figshare
- Additional file 1 of CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in gliomaLiu, S. John, Martina Malatesta, Brian V. Lien, Parna Saha, Shivani S. Thombare, Hong, Sung Jun, Leslie Pedraza, Mark Koontz, Kyounghee Seo, Max A. Horlbeck et al. · 2020 · Figshare
- Identification et caractérisation de facteurs impliqués dans la réponse cellulaire aux ARN double brinOlivier Petitjean · 2020
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- Optimized parameters for CRISPR-Cas9 interference library designSmriti Srikanth, Fengyi Zheng, Laura M. Drepanos, Spencer T. Shah, E L Kaplan, Daytan Gibson, Grace O Lynch, Allison Uebele, Ganna Reint, Sarra Merzouk et al. · 2026 · Cell Genomics
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