Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation
Doksani, Ylli, Wu, John Y., de Lange, Titia, Zhuang, Xiaowei·2013·Cell
Cited by (493)
Items 101–200 of 493
- Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancersRobert Lu, Hilda A. Pickett · 2022 · Open Biology
- Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of TelomeresCaitlin M. Roake, Steven E. Artandi · 2017 · Cold Spring Harbor Perspectives in Medicine
- The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompactionLeonid A. Timashev, Hazen P. Babcock, Xiaowei Zhuang, Titia de Lange · 2017 · Genes & Development
- The end protection problem—an unexpected twist in the tailRuis, Phil, Boulton, Simon J. · 2021 · Genes & Development
- Telomeres and Cancer: Resolving the ParadoxJoe Nassour, Tobias T. Schmidt, Jan Karlseder · 2021 · Annual Review of Cancer Biology
- SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediatesJaya Sarkar, Bingbing Wan, Jinhu Yin, Haritha Vallabhaneni, Kent Horvath, Tomasz Kulikowicz, Vilhelm A. Bohr, Yanbin Zhang, Ming Lei, Yie Liu · 2015 · Nucleic Acids Research
- Mir‐23a induces telomere dysfunction and cellular senescence by inhibiting TRF 2 expressionZhenhua Luo, Xuyang Feng, Haoli Wang, Weiyi Xu, Yong Bo Zhao, Wenbin Ma, Songshan Jiang, Dan Liu, Junjiu Huang, Zhou Songyang · 2015 · Aging Cell
- TRF2-independent chromosome end protection during pluripotencyPhil Ruis, David Van Ly, Valérie Borel, Georgia Rose Kafer, Afshan McCarthy, Steven A. Howell, Robert A. Blassberg, Ambrosius P. Snijders, James Briscoe, Kathy K. Niakan et al. · 2020 · Nature
- Substrate specificity of the MUS81-EME2 structure selective endonucleaseAnna Elena Pepe, Stephen Craig West · 2013 · Nucleic Acids Research
- A loopy view of telomere evolutionTitia de Lange · 2015 · Frontiers in Genetics
- CST–Polymeraseα-primase solves a second telomere end-replication problemH. Takai, Valentina Aria, Pamela Borges, Joseph T. P. Yeeles, T. de Lange · 2024 · Nature
- Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implicationsPaolo Boscolo‐Rizzo, Maria Cristina Da Mosto, Enrica Rampazzo, Silvia Giunco, Annarosa Del Mistro, Anna Menegaldo, Lorena Baboçi, Monica Mantovani, Giancarlo Tirelli, Anita De Rossi · 2016 · Cancer and Metastasis Reviews
- Telomerase: Key regulator of inflammation and cancerLele Wu, Kerem Fidan, Jae‐Young Um, Kwang Seok Ahn · 2020 · Pharmacological Research
- The shelterin complex and hematopoiesisMorgan Jones, Kamlesh Kumar Bisht, Sharon A. Savage, Jayakrishnan Nandakumar, Catherine E. Keegan, Ivan P. Maillard · 2016 · Journal of Clinical Investigation
- SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damageAngela Rizzo, Sara Iachettini, Erica Salvati, Pasquale Zizza, Carmen Maresca, Carmen D’Angelo, Delphine Benarroch, Angela Capolupo, Federica Del Gaudio, Sandro Cosconati et al. · 2016 · Nucleic Acids Research
- Mitotic functions of poly(ADP-ribose) polymerasesDea Slade · 2019 · Biochemical Pharmacology
- Telomeres and Telomerase in the Control of Stem CellsAlexey Yu. Lupatov, K. N. Yarygin · 2022 · Biomedicines
- The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomesZhuo Wang, Paul M. Lieberman · 2016 · RNA Biology
- The telomeric DNA damage response occurs in the absence of chromatin decompactionAleksandra Vančevska, Kyle M. Douglass, Verena Pfeiffer, Suliana Manley, Joachim Lingner · 2017 · Genes & Development
- Subtelomeric Transcription and its RegulationMarta Kwapisz, Antonin Morillon · 2020 · Journal of Molecular Biology
- Emerging roles of CST in maintaining genome stability and human diseaseJ. Stewart, Yi-Lin Wang, Stephanie M. Ackerson, P. L. Schuck · 2018 · Frontiers in Bioscience
- POT1-TPP1 telomere length regulation and diseaseTomas M. Aramburu, Sarah M. Plucinsky, Emmanuel Skordalakes · 2020 · Computational and Structural Biotechnology Journal
- Telomeres, cellular senescence, and aging: past and futureMadeline Eppard, João F. Passos, Stella G. Victorelli · 2023 · Biogerontology
- Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on AgeingPauline Billard, Delphine Poncet · 2019 · International Journal of Molecular Sciences
- TPP1 Blocks an ATR-Mediated Resection Mechanism at TelomeresTatsuya Kibe, Michal Zimmermann, Titia de Lange · 2016 · Molecular Cell
- Metabolism of DNA secondary structures at the eukaryotic replication forkAna María León-Ortiz, Jennifer M. Svendsen, Simon J. Boulton · 2014 · DNA repair
- RETRACTED: SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation EpigeneticallyTianming Li, Qidi Zheng, Jiahui An, Mengying Wu, Haiyan Li, Xin Gui, Hu Pu, Dongdong Lu · 2015 · Molecular Therapy · Retracted
- Single molecule localization imaging of exosomes using blinking silicon quantum dotsShenfei Zong, Junzhu Zong, Chen Chen, Xiaoyue Jiang, Yizhi Zhang, Zhuyuan Wang, Yiping Cui · 2017 · Nanotechnology
- Telomere function and regulation from mouse models to human ageing and diseaseCorey Winston Jones-Weinert, Laura Mainz, Jan Karlseder · 2024 · Nature Reviews Molecular Cell Biology
- The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break RepairKeren Baranes‐Bachar, Adva Levy‐Barda, Judith Oehler, Dylan A. Reid, Isabel Soria‐Bretones, Ty C. Voss, Dudley Chung, Yoon Park, Chao Liu, Jong‐Bok Yoon et al. · 2018 · Molecular Cell
- SLX4: multitasking to maintain genome stabilityJean-Hugues Guervilly, Pierre-Henri L. Gaillard · 2018 · Critical Reviews in Biochemistry and Molecular Biology
- The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeresAdélaïde Saint-Léger, Mélanie Koelblen, Livia Civitelli, Amadou Bah, Nadir Djerbi, Marie-Josèphe E. Giraud-Panis, Arturo Londoño‐Vallejo, Fiorentina Ascenzioni, Éric Gilson · 2014 · Cell Cycle
- No DDRama at chromosome ends: TRF2 takes centre stageSascha Feuerhahn, Liuh‐Yow Chen, Brian Luke, Antônio Porro · 2015 · Trends in Biochemical Sciences
- Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative StressMariarosaria De Rosa, Samuel A. Johnson, Patricia Lynn Opresko · 2021 · Frontiers in Cell and Developmental Biology
- Characterization of t-loop formation by TRF2Leonid A. Timashev, Titia de Lange · 2020 · Nucleus
- TPP1 Blocks an ATR-Mediated Resection Mechanism at TelomeresTatsuya Kibe, Michal Zimmermann, Titia de Lange · 2017 · Molecular Cell
- Targeting 24 bp within Telomere Repeat Sequences with Tandem Tetramer Pyrrole–Imidazole Polyamide ProbesYusuke Kawamoto, Asuka Sasaki, Anandhakumar Chandran, Kaori Hashiya, Satoru Ide, Toshikazu Bando, Kazuhiro Maeshima, Hiroshi Sugiyama · 2016 · Journal of the American Chemical Society
- ALU non-B-DNA conformations, flipons, binary codes and evolutionAlan G. Herbert · 2020 · Royal Society Open Science
- DNA excision repair at telomeresPingping Jia, Chengtao Her, Weihang Chai · 2015 · DNA repair
- Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repairGlousker, Galina, Briod, Anna‐Sophia, Quadroni, Manfredo, Lingner, Joachim · 2020 · The EMBO Journal
- DNA damage processing at telomeres: The ends justify the meansElise Fouquerel, Dhvani Parikh, Patricia Lynn Opresko · 2016 · DNA repair
- MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancerRoberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D’Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna et al. · 2022 · EMBO Molecular Medicine
- Shelterin is a dimeric complex with extensive structural heterogeneityZinder, John C., Olinares, Paul Dominic B., Svetlov, Vladimir, Bush, Martin W., Nudler, Evgeny, Chait, Brian T., Walz, Thomas, de Lange, Titia · 2022 · Proceedings of the National Academy of Sciences
- TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organizationAlessandra Galati, Emanuela Micheli, Claudia Alicata, Tiziano Ingegnere, Alessandro Cicconi, Miriam Caroline Pusch, Marie-Josèphe E. Giraud-Panis, Éric Gilson, Stefano Cacchione · 2015 · Nucleic Acids Research
- Telomere Dysfunction, Chromosomal Instability and CancerJitendra Kumar Meena, K. Lenhard Rudolph, Çagatay Güneş · 2015 · Recent results in cancer research/Recent Results in Cancer Research
- Emerging roles of telomeric chromatin alterations in cancerStefano Cacchione, Annamaria Biroccio, Angela Rizzo · 2019 · Journal of Experimental & Clinical Cancer Research
- Mechanisms driving the ageing heartRhys Anderson, Gavin David Richardson, João F. Passos · 2017 · Experimental Gerontology
- Life and cancer without telomerase: ALT and other strategies for making sure ends (don’t) meetManasi S. Apte, Julia Promisel Cooper · 2016 · Critical Reviews in Biochemistry and Molecular Biology
- DNA double strand break responses and chromatin alterations within the aging cellKarolin Klement, Aaron A. Goodarzi · 2014 · Experimental Cell Research
- Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1bK. Kratz, T. de Lange · 2018 · Journal of Biological Chemistry
- A beginning of the end: new insights into the functional organization of telomeresAshley M. Wood, Kyle Vaughn Laster, Ellen L. Rice, Steven T. Kosak · 2015 · Nucleus
- ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2Alina Bluhm, Nikenza Viceconte, Fudong Li, Grishma Rane, Sandra Ritz, Suman Wang, Michal Levin, Yunyu Shi, Dennis Kappei, Falk Butter · 2018 · Nucleic Acids Research
- A New View of the T-Loop Junction: Implications for Self-Primed Telomere Extension, Expansion of Disease-Related Nucleotide Repeat Blocks, and Telomere EvolutionĽubomír Tomáška, Jozef Nosek, Anirban Kar, Smaranda Willcox, Jack D. Griffith · 2019 · Frontiers in Genetics
- The evolution of metazoan shelterinLogan R. Myler, Charles G. Kinzig, N. Sasi, George Zakusilo, Sarah W. Cai, T. de Lange · 2021 · Genes & Development
- Helicobacter pylori ‐positive chronic atrophic gastritis and cellular senescenceShi‐yu Zheng, Lu Zhu, Luyi Wu, Huirong Liu, Xiao‐peng Ma, Qi Li, Meng‐die Wu, W Wang, Jing Li, Huangan Wu · 2022 · Helicobacter
- (–)-Epigallocatechin-3-Gallate Protects Human Skin Fibroblasts from Ultraviolet a Induced PhotoagingYuanyuan Jia, Qiuyu Mao, Jingyi Yang, Na Du, Yuan Zhu, Wei Min · 2023 · Clinical Cosmetic and Investigational Dermatology
- Telomere-Regulating Genes and the Telomere Interactome in Familial CancersCarla Daniela Robles‐Espinoza, Martin Del Castillo Velasco‐Herrera, Nicholas K. Hayward, David J. Adams · 2014 · Molecular Cancer Research
- Tandem trimer pyrrole–imidazole polyamide probes targeting 18 base pairs in human telomere sequencesYusuke Kawamoto, Asuka Sasaki, Kaori Hashiya, Satoru Ide, Toshikazu Bando, Kazuhiro Maeshima, Hiroshi Sugiyama · 2015 · Chemical Science
- Balance between senescence and apoptosis is regulated by telomere damage–induced association between p16 and caspase-3Shanmugam Panneer Selvam, Braden M. Roth, Rose Nganga, Jisun Kim, Marion A. Cooley, Kristi L. Helke, Charles D. Smith, Besim Öğretmen · 2018 · Journal of Biological Chemistry
- Surface Plasmon Localization-Based Super-resolved Raman MicroscopyHongki Lee, Kyungnam Kang, Kentaro Mochizuki, Chang‐Hun Lee, Kar‐Ann Toh, Seung Ah Lee, Katsumasa Fujita, Donghyun Kim · 2020 · Nano Letters
- Telomeres as hotspots for innate immunity and inflammationJoe Nassour, Sara Przetocka, Jan Karlseder · 2023 · DNA repair
- Precarious maintenance of simple DNA repeats in eukaryotesAlexander J. Neil, Jane C. Kim, Sergei M. Mirkin · 2017 · BioEssays
- DNA–dependent protein kinase in telomere maintenance and protectionJiang-Dong Sui, Shichuan Zhang, Benjamin P.C. Chen · 2020 · Cellular & Molecular Biology Letters
- Twenty years of t-loops: A case study for the importance of collaboration in molecular biologyĽubomír Tomáška, Anthony J. Cesare, Taghreed M. Al-Turki, Jack D. Griffith · 2020 · DNA repair
- STORM imaging of mitochondrial dynamics using a vicinal-dithiol-proteins-targeted probeBingling Chen, Wanjun Gong, Zhigang Yang, Wenhui Pan, Peter Verwilst, Jin Woo Shin, Wei Yan, Liwei Liu, Junle Qu, Jong Seung Kim · 2020 · Biomaterials
- Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgeJérôme D. Robin, Frédérique Magdinier · 2016 · Frontiers in Genetics
- Telomerase promotes formation of a telomere protective complex in cancer cellsOmesha N. Perera, Alexander P. Sobinoff, Erdahl Teber, Ashley Harman, Michelle F. Maritz, Sile F. Yang, Hilda A. Pickett, Anthony J. Cesare, Jonathan W. Arthur, Karen L. MacKenzie et al. · 2019 · Science Advances
- TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere DysfunctionWilliam C. Drosopoulos, Zhong Deng, Shyam Twayana, Settapong T Kosiyatrakul, Olga V. Vladimirova, Paul M. Lieberman, Carl L. Schildkraut · 2020 · Cell Reports
- Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtentionde Bardet, Javier Curi, Cardentey, Celeste Ramírez, González, Belkis López, Patrone, Deanira, Mulet, Idania Lores, Siniscalco, Dario, Robinson-Agramonte, María de los Angeles · 2023 · BioTech
- The many facets of homologous recombination at telomeresClémence Claussin, Michael Chang · 2015 · Microbial Cell
- Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2Parminder Kaur, Dong Wu, Jiangguo Lin, Preston J. Countryman, Kira Bradford, Dorothy A. Erie, Robert E. Riehn, Patricia Lynn Opresko, Hong Wang · 2016 · Scientific Reports
- Telomerase and Telomeres in Endometrial CancerRafah Alnafakh, Meera Adishesh, Lucy Button, Gabriele Christine Saretzki, Dharani Kosala Hapangama · 2019 · Frontiers in Oncology
- Persistent telomere cohesion protects aged cells from premature senescenceKameron Azarm, Amit Bhardwaj, Eugenie Kim, Susan Harless Smith · 2020 · Nature Communications
- Studying the organization of DNA repair by single-cell and single-molecule imagingStephan Uphoff, Achillefs N. Kapanidis · 2014 · DNA repair
- Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probesYanxiang Ni, Bo Cao, Tszshan Ma, Gang Niu, Yingdong Huo, Jiandong Huang, Danni Chen, Yi Liu, Bin Yu, Michael Q. Zhang et al. · 2017 · eLife
- The Connection Between Cell Fate and TelomereAyşe Başak Engin, Atilla Engin · 2021 · Advances in experimental medicine and biology
- Super-resolution microscopy to decipher multi-molecular assembliesChristian Sieben, Kyle M. Douglass, Paul Guichard, Suliana Manley · 2018 · Current Opinion in Structural Biology
- Inhibition of MRN activity by a telomere protein motifFreddy Khayat, Elda Cannavò, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher D. Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr et al. · 2021 · Nature Communications
- Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein CompositionClaire Ghilain, Éric Gilson, Marie-Josèphe E. Giraud-Panis · 2021 · Cells
- Super-Resolution Molecular and Functional Imaging of Nanoscale Architectures in Life and Materials ScienceSatoshi Habuchi · 2014 · Frontiers in Bioengineering and Biotechnology
- Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extensionRosa María Porreca, Galina Glousker, Aya Awad, Maria I Matilla Fernandez, Anne Gibaud, Christian Naucke, Scott B. Cohen, Tracy M. Bryan, Yehuda Tzfati, Irena Drašković et al. · 2018 · Nucleic Acids Research
- TRF1 as a major contributor for telomeres' shortening in the context of obesityLucas Kich Grün, Nevton Teixeira da Rosa‐Junior, Lúcia von Mengden, Marco Antônio De Bastiani, Mariana Migliorini Parisi, Rafael Calixto Bortolin, Patrícia Lavandoski, Vinícius Pierdoná, Letícia Biscaino Alves, José Cláudio Fonseca Moreira et al. · 2018 · Free Radical Biology and Medicine
- Advanced imaging techniques for tracking drug dynamics at the subcellular levelChengying Zhang, Zhiqi Tian, Rui Chen, Fiona Rowan, Kangqiang Qiu, Yujie Sun, Jun‐Lin Guan, Jiajie Diao · 2023 · Advanced Drug Delivery Reviews
- Spatial distribution of high copy number plasmids in bacteriaYong Wang · 2017 · Plasmid
- To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End ProtectionStephanie M. Ackerson, Carlan V. Romney, P. Logan Schuck, Jason A. Stewart · 2021 · Frontiers in Cell and Developmental Biology
- Role of angiotensin II in agingWenmin Yi, Fei Chen, Huiji Zhang, Peng Tang, Minghao Yuan, Jie Wen, Shengyuan Wang, Zhiyou Cai · 2022 · Frontiers in Aging Neuroscience
- Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest PointPavel Veverka, Tomáš Janovič, Ctirad Hofr · 2019 · International Journal of Molecular Sciences
- How do telomeres and NHEJ coexist?Stéphane Marcand · 2014 · Molecular & Cellular Oncology
- PHF11 promotes DSB resection, ATR signaling, and HRYi Gong, Naofumi Handa, Stephen C. Kowalczykowski, Titia de Lange · 2017 · Genes & Development
- Replication stress as a source of telomere recombination during replicative senescence inSaccharomyces cerevisiaeMarie‐Noëlle Simon, Dmitri Churikov, Vincent Géli · 2016 · FEMS Yeast Research
- Single-Molecule Studies of Telomeres and TelomeraseJoseph W. Parks, Michael D. Stone · 2017 · Annual Review of Biophysics
- The C-Terminal Extension Unique to the Long Isoform of the Shelterin Component TIN2 Enhances Its Interaction with TRF2 in a Phosphorylation- and Dyskeratosis Congenita Cluster-Dependent FashionNya D. Nelson, Lois M. Dodson, Laura Escudero, Ann T. Sukumar, Christopher L. Williams, Ivana Mihalek, Alessandro Baldan, Duncan M. Baird, Alison A. Bertuch · 2018 · Molecular and Cellular Biology
- Functions of ADP-ribose transferases in the maintenance of telomere integrityDaniela Muoio, Natalie Laspata, Elise Fouquerel · 2022 · Cellular and Molecular Life Sciences
- Telomere Length Changes in Cancer: Insights on Carcinogenesis and Potential for Non-Invasive Diagnostic StrategiesZuzana Holesova, Lucia Krasničanová, Rami Saade, Ondrej Pös, Jaroslav Budiš, Juraj Gazdarica, Vanda Repiská, Tomáš Szemes · 2023 · Genes
- Transcription of telomeric DNA leads to high levels of homologous recombination and t-loopsAnirban Kar, Smaranda Willcox, Jack D. Griffith · 2016 · Nucleic Acids Research
- Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores itIvona Nečasová, Eliška Janoušková, Tomáš Klumpler, Ctirad Hofr · 2017 · Nucleic Acids Research
- Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous analysis of telomere length and RNA-seq in the same human embryonic stem cellHua Wang, Kunshan Zhang, Yifei Liu, Yudong Fu, Shan Gao, Peng Gong, Haiying Wang, Zhongcheng Zhou, Ming Zeng, Zhenfeng Wu et al. · 2017 · BMC Biology
- TRF2 Protein Interacts with Core Histones to Stabilize Chromosome EndsAkimitsu Konishi, Takashi Izumi, Shigeomi Shimizu · 2016 · Journal of Biological Chemistry
- Telomere Length and Telomerase Activity in Bovine Pre‐implantation Embryos In VitroG. C. Gilchrist, P Kurjanowicz, FV Mereilles, W. Allan King, Jonathan LaMarre · 2014 · Reproduction in Domestic Animals
- Moments reconstruction and local dynamic range compression of high order superresolution optical fluctuation imagingXiyu Yi, Sungho Son, Ryoko Ando, Atsushi Miyawaki, Shimon Weiss · 2019 · Biomedical Optics Express