Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
Zhang, Yanjia J., Reddy, Manchi C., Ioerger, Thomas R., Rothchild, Alissa C., Dartois, Veronique, Schuster, Brian M., Trauner, Andrej, Wallis, Deeann +5 more·2013·Cell
Cited by (356)
Items 301–356 of 356
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- A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthFrancesca G. Tomasi, 木村聡, Eric J. Rubin, Matthew K. Waldor · 2023 · eLife
- Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosisMehak Zahoor Khan, Deborah M. Hunt, Biplab Singha, Yogita Kapoor, Nitesh Kumar Singh, D. V. Sai Prasad, Dharmarajan Sriram, Divya Tej Sowpati, Luiz Pedro S. de Carvalho, Vinay Kumar Nandicoori · 2023 · eLife
- Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosisMehak Zahoor Khan, Deborah M. Hunt, Biplab Singha, Yogita Kapoor, Nitesh Kumar Singh, D. V. Sai Prasad, Dharmarajan Sriram, Divya Tej Sowpati, Luiz Pedro S. de Carvalho, Vinay Kumar Nandicoori · 2024 · eLife
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- Mtb takes a TrpMirella Bucci · 2014 · Nature Chemical Biology
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- [Clinical study of the sulfamethoxazole--trimethoprim combination in urinary infections (apropos of 40 cases)].M.M. Plauchu, V Jandot · 1972 · PubMed
- Global assessment of Mycobacterium avium subspecies hominissuis genetic requirement for growth and virulenceMarte Singsås Dragset, Thomas R. Ioerger, Maja Loevenich, Markus Haug, Niruja Sivakumar, Anne Marstad, Père-Joan Cardona, Geir Klinkenberg, Eric J. Rubin, Magnus Steigedal et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Development of a Novel Method for Genome-wide Identification of Proteins Exported during Infection and Functional Studies of One in vivo Exported Protein in Mycobacterium tuberculosisEllen F. Perkowski · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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- A Stealthy Fungal Attack Requires an Equally Clandestine Approach to Onychomycosis TreatmentAditya Gupta, Jessie Carviel, Neil H. Shear · 2019 · Journal of the American Podiatric Medical Association
- Inhibition and reaction mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase: A potential target for novel drug designPreeti Kundu · 2020
- Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape TownSabelo Hadebe, Melissa Dalcina Chengalroyen, Reto Guler, Kehilwe C. Nakedi, Anastasia Sideris Koch, Mohau S. Makatsa, Muki Shehu Shey, Suraj P. Parihar, Bryan D. Bryson, Mohlopheni Jackson Marakalala et al. · 2019 · Gates Open Research
- Faculty Opinions recommendation of Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases.Willem Joost Wiersinga, Bastiaan W. Haak · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape TownSabelo Hadebe, Melissa Dalcina Chengalroyen, Reto Guler, Kehilwe C. Nakedi, Anastasia Sideris Koch, Mohau S. Makatsa, Muki Shehu Shey, Suraj P. Parihar, Bryan D. Bryson, Mohlopheni Jackson Marakalala et al. · 2019 · Gates Open Research
- Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape TownSabelo Hadebe, Melissa Dalcina Chengalroyen, Reto Guler, Kehilwe C. Nakedi, Anastasia Sideris Koch, Mohau S. Makatsa, Muki Shehu Shey, Suraj P. Parihar, Bryan D. Bryson, Mohlopheni Jackson Marakalala et al. · 2019 · Gates Open Research
- Multifaceted roles of mycobacterium cell envelope glycolipids during host cell membrane interactionsManjari Mishra, Shobhna Kapoor · 2022 · Elsevier eBooks
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- A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthFrancesca G. Tomasi, 木村聡, Eric J. Rubin, Matthew K. Waldor · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthFrancesca G. Tomasi, 木村聡, Eric J. Rubin, Matthew K. Waldor · 2023 · eLife
- The Role of Gut Microbiota-derived Tryptophan Metabolites in Mycobacterium tuberculosis Infection: A Mini-ReviewNovi Maulina, Zinatul Hayati, Kartini Hasballah, Zulkarnain Zulkarnain, Baidillah Zulkifli · 2023 · The International Journal of Tropical Veterinary and Biomedical Research
- Chemical inhibition of histidine biosynthesis curtails M. tuberculosis infectionSatish Tiwari, Mohammed Ahmad, Varun Kumar, Deepsikha Kar, Swati Kumari, Abhisek Dwivedy, Ravi Kant Pal, Amit Kumar Mohapatra, Vaibhav Kumar Nain, Vishawjeet Barik et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosisAmit Singh, Somnath Shee, Reshma TV, Karthikeyan Mohanraj, Mayashree Das, Nitish Malhotra, Devleena Bandopadhyay, Hussain Beig, Shalini Birua, Shreyas Niphadkar et al. · 2023 · Research Square
- Towards a New Class of Anti-Tuberculosis Drugs: Design and Synthesis of AnPRT TS AnaloguesMason, Emily · 2023
- Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosisMehak Zahoor Khan, Deborah M. Hunt, Biplab Singha, Yogita Kapoor, Nitesh Kumar Singh, D. V. Sai Prasad, Dharmarajan Sriram, Divya Tej Sowpati, Luiz Pedro S. de Carvalho, Vinay Kumar Nandicoori · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- KatG inactivation generates vulnerabilities in isoniazid resistant strains of Mycobacterium tuberculosisXinyue Wang, William J Jowsey, Chen‐Yi Cheung, Noon E. J. Seeto, Natalie J.E. Waller, Michael T Chrisp, Amanda L. Peterson, Brunda Nijagal, Peter C. Fineran, Gregory Murray Cook et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Targeted Disruption of the Aspartate Pathway: A Promising Approach for Combating Persistent Tuberculosis InfectionsGhodke Babasaheb Shivanath, Agarwal Akansha Singhal · 2023 · International Journal of Zoological Investigations
- Additional file 4 of Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophagesXiao, Guohui, Su Zhang, Like Zhang, Shuyan Liu, Guobao Li, Min Ou, Xuan Zeng, Zhaoqin Wang, Guoliang Zhang, Shuihua Lu · 2022 · Figshare
- Additional file 5 of Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophagesGuohui Xiao, Su Zhang, Like Zhang, Shuyan Liu, Guobao Li, Min Ou, Xuan Zeng, Zhaoqin Wang, Guoliang Zhang, Shuihua Lu · 2022 · Figshare
- Additional file 3 of Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophagesGuohui Xiao, Su Zhang, Like Zhang, Shuyan Liu, Guobao Li, Min Ou, Xuan Zeng, Zhaoqin Wang, Guoliang Zhang, Shuihua Lu · 2022 · Figshare
- Additional file 2 of Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophagesXiao, Guohui, Su Zhang, Like Zhang, Shuyan Liu, Guobao Li, Min Ou, Xuan Zeng, Zhaoqin Wang, Guoliang Zhang, Shuihua Lu · 2022 · Figshare
- Author Response: A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthFrancesca G. Tomasi, 木村聡, Eric J. Rubin, Matthew K. Waldor · 2023 · eLife
- Reviewer #1 (Public Review): Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis2024 · eLife
- Author response: Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosisMehak Zahoor Khan, Deborah M. Hunt, Biplab Singha, Yogita Kapoor, Nitesh Kumar Singh, D. V. Sai Prasad, Dharmarajan Sriram, Divya Tej Sowpati, Luiz Pedro S. de Carvalho, Vinay Kumar Nandicoori · 2024 · eLife
- Uncovering asparagine utilization pathway, a critical requirement for mycobacterial pH-driven adaptation at the host pathogen crossroadsBhanwar Bamniya, Kajal Kajal, Khushboo Mehta, Dibyendu Sarkar · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Random barcode transposon-site sequencing in Mycobacterium tuberculosis reveals the functions of uncharacterized genesKayla M. Dinshaw, Katie A. Lien, Matthew Knight, Sorel V. Yigma Ouonkap, Hualan Liu, David F. Savage, Hans K. Carlson, Adam M. Deutschbauer, Sarah A. Stanley · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 1 of Untargeted metabolomics analysis reveals Mycobacterium tuberculosis strain H37Rv specifically induces tryptophan metabolism in human macrophagesXiao, Guohui, Zhang, Su, Zhang, Like, Liu, Shuyan, Li, Guobao, Ou, Min, Zeng, Xuan, Wang Zhaoqin, Zhang, Guoliang, Lu, Shuihua · 2022 · Figshare
- Exploring NAD(+) metabolism in host-pathogen interactionsBelinha, Ana, Joana Gaifem, Inês Mesquita, Ricardo Silvestre · 2016 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
- Impact of trpB and trpA on acid stress response and malolactic fermentation in Lactiplantibacillus plantarum XJ25Yuxin Yuan, Yueyao Li, Qiang Meng, Shuwen Liu, Kan Shi · 2025 · Food Bioscience
- Emerging therapeutic drug targets in amino acid and protein biosynthesis pathways against ESKAPE and non-ESKAPE pathogens: a comprehensive reviewRuchika Maurya, Amneet Kaur Badwal, Sushma Singh · 2026 · Archives of Microbiology
- Interaction of Mycobacterium tuberculosis with the Host from the Pathogen’s PerspectiveVladimir Yeremeev, Шепелькова Галина Сергеевна · 2026 · Biochemistry (Moscow)
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- A Conserved Mycobacterial Nucleomodulin Hijacks the Host COMPASS Complex to Reprogram Pro-Inflammatory Transcription and Promote Intracellular SurvivalLiu Chen, Baojie Duan, Pingping Chen, Qiang Jiang, Yifan Wang, Lu Lu, Yingyu Chen, Changmin Hu, Lei Zhang, Aizhen Guo · 2026 · eLife
- Dynamic remodeling of the pulmonary microenvironment driven by Mycobacterium tuberculosis infection: Mechanisms and implicationsRuijun Liu, Lulu Wang, Yan Xiong, Beibei Fu, Haibo Wu · 2026 · International Immunopharmacology
- Circulating metabolites associated with protection against Mycobacterium tuberculosis infection and inhibition of mycobacterial growthTodia Pediatama Setiabudiawan, Lika Apriani, Julián Ávila-Pacheco, Edwin Ardiansyah, Vinod Kumar, Bachti Alisjahbana, Ayesha J Verrall, Andrew R. DiNardo, Agnes Rengga Indrati, Vera P. Mourits et al. · 2026 · Communications Biology
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- Burkholderia cenocepacia physiology and molecular adaptations to the acidic pH of the CF nutritional environmentL. Daniela Morales, Bhavjinder Dhillon, J.C. Grigg, Ananya Saraph, Lindsay D. Eltis, Robert E. W. Hancock, Michael E. P. Murphy · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Transcriptional control of asparagine utilization regulates mycobacterial pH-driven adaptation at the host–pathogen crossroadsBhanwar Bamniya, Kajal, Khushboo Mehta, Dibyendu Sarkar · 2026 · Journal of Biological Chemistry
- Toxin-mediated tRNATrp depletion drives Trp-codon-dependent reprogramming in Mycobacterium tuberculosis while selectively enriching the PDIM biosynthetic machinerySafreen Sain, Unnati Chauhan, Valdir C. Barth Jr, Eduardo Artur Troian, Bruno Lopes Abbadi, Basanti Malakar, Robert N. Husson, Nancy A. Woychik · 2026 · PLoS Pathogens
- Elevated Kynurenine to Tryptophan Ratio in Peripheral Blood Distinguishes Infectious from Non-Infectious Causes of Respiratory Disease and is Highest in Active Tuberculosis—A Diagnostic Accuracy StudyWayne Howard, Erica J. Shaddock, Sarah Lynn Stacey, Kennedy N. Otwombe, Heena Ranchod, Melinda Shelley Suchard · 2026 · International Journal of Tryptophan Research
- BindingDB Entry 50008997: Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.BindingDB · 2021 · UC San Diego