Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling
Weissmueller, Susann, Manchado, Eusebio, Saborowski, Michael, Morris, John P., Wagenblast, Elvin, Davis, Carrie A., Moon, Sung-Hwan, Pfister, Neil T. +10 more·2014·Cell
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- Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal AdenocarcinomaNisebita Sahu, Emily Chan, Felix Chu, Thinh Q. Pham, Hartmut Koeppen, William F. Forrest, Mark A. Merchant, Jeff Settleman · 2017 · Molecular Cancer Therapeutics
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- p53 and its mutants on the slippery road from stemness to carcinogenesisAlina Molchadsky, Varda Rotter · 2017 · Carcinogenesis
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- Mutant p53 and chromatin regulationCarol L. Prives, Scott W. Lowe · 2015 · Nature
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- Impact of p53 and PDGFR‐β Expression on Metastasis and Prognosis of Patients with Pancreatic CancerHiroshi Kurahara, Kosei Maemura, Yuko Mataki, Masahiko Sakoda, Hiroyuki Shinchi, Shoji Natsugoe · 2016 · World Journal of Surgery
- Unraveling cancer lineage drivers in squamous cell carcinomasYinglu Guan, Guan Wang, Danielle Fails, Priyadharsini Nagarajan, Yejing Ge · 2019 · Pharmacology & Therapeutics
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- Different impacts of TP53 mutations on cell cycle-related gene expression among cancer typesKeiju Sasaki, Shinʼ ichi Takahashi, Kota Ouchi, Yasufumi Otsuki, Shonosuke Wakayama, Chikashi Ishioka · 2023 · Scientific Reports
- Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancerRohit Sarkar, Zhihong Xu, Chamini Jayamali Perera, Minoti Vivek Apte · 2023 · Seminars in Cancer Biology
- A Five-Gene Signature Predicts Prognosis in Patients with Kidney Renal Clear Cell CarcinomaYueping Zhan, Wenna Guo, Ying Zhang, Qiang Wang, Xin‐Jian Xu, Liucun Zhu · 2015 · Computational and Mathematical Methods in Medicine
- IRTKS is correlated with progression and survival time of patients with gastric cancerLiyu Huang, Xuefei Wang, Xiaofang Cui, Li He, Junjie Zhao, Chong-Chao Wu, Lingqiang Min, Zhicheng Zhou, Lixin Wan, Yuping Wang et al. · 2017 · Gut
- Impact of RNA-Guided Technologies for Target Identification and DeconvolutionMyles Fennell, Qing Xiang, Alexia Hwang, Chong Chen, Chun‐Hao Huang, Chi-Chao Chen, Raphael A. Pelossof, Ralph J. Garippa · 2014 · SLAS DISCOVERY
- p53: Multiple Facets of a Rubik's CubeYun Zhang, Guillermina Lozano · 2016 · Annual Review of Cancer Biology
- Salvation of the fallen angel: Reactivating mutant p53Li Yang, Zhuoyi Wang, Yuchen Chen, Robert B. Petersen, Ling Zheng, Kun Huang · 2019 · British Journal of Pharmacology
- Efficient Propagation of Circulating Tumor Cells: A First Step for Probing Tumor MetastasisJerry Xiao, Joseph R. McGill, Kelly Patrick Stanton, Joshua D. Kassner, Sujata Choudhury, Richard Schlegel, Zuben E. Sauna, Paula Raffin Pohlmann, Seema Agarwal · 2020 · Cancers
- MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locusJack D. Godfrey, Jennifer P. Morton, Ania Wilczynska, Owen James Sansom, Martin Bushell · 2018 · Cell Death and Disease
- Pancreatic Cancer Gene Therapy Delivered by NanoparticlesTrevin Robert Kurtanich, Nicole Roos, Guanmeng Wang, Jesse Yang, Alan Wang, Eun Ji Chung · 2018 · SLAS TECHNOLOGY
- Identification of genomic alterations and associated transcriptomic profiling reveal the prognostic significance of MMP14 and PKM2 in patients with pancreatic cancerHaiwei Wang, Xinrui Wang, Liangpu Xu, Yingying Lin, Ji Zhang, Hua Cao · 2020 · Aging
- Computational and experimental characterization of the novel ECM glycoprotein SNED1 and prediction of its interactomeSylvain D. Vallet, Martin N. Davis, Anna Barqué, Ali H. Thahab, Sylvie Ricard‐Blum, Alexandra Naba · 2021 · Biochemical Journal
- NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic networkEleonora Mammarella, Carlotta Zampieri, Emanuele Panatta, Gerry Melino, Ivano Amelio · 2021 · Biology Direct
- Transforming growth factor-β in pancreatic diseases: Mechanisms and therapeutic potentialQi Zhou, Shilin Xia, Fangyue Guo, Fenglin Hu, Zhizhou Wang, Yujia Ni, Tianfu Wei, Hong Xiang, Dong Shang · 2019 · Pharmacological Research
- A Pipeline for Drug Target Identification and ValidationEusebio Manchado, Chun‐Hao Huang, Nilgun Tasdemir, Darjus Felix Tschaharganeh, John Erby Wilkinson, Scott W. Lowe · 2016 · Cold Spring Harbor Symposia on Quantitative Biology
- Development of a Method to Implement Whole-Genome Bisulfite Sequencing of cfDNA from Cancer Patients and a Mouse Tumor ModelElaine C. Maggi, Silvia Gravina, Haiying Cheng, Bilal Piperdi, Ziqiang Yuan, Xiao Dong, Steven K. Libutti, Jan Vijg, Cristina Montagna · 2018 · Frontiers in Genetics
- Mouse-Derived Allografts: A Complementary Model to the KPC Mice on Researching Pancreatic Cancer In VivoJie Li, Weikun Qian, Tao Qin, Ying Xiao, Liang Cheng, Junyu Cao, Xin Chen, Qingyong Ma, Zheng Wu · 2019 · Computational and Structural Biotechnology Journal
- High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancerAkio Tsutaho, Ari Hashimoto, Shigeru Hashimoto, Soichiro Hata, Shion Kachi, Satoshi Hirano, Hisataka Sabe · 2020 · Cell Communication and Signaling
- Knockout of the gene encoding the extracellular matrix protein SNED1 results in early neonatal lethality and craniofacial malformationsAnna Barqué, Kyleen Jan, Emanuel De La Fuente, Christina L. Nicholas, Richard O. Hynes, Alexandra Naba · 2020 · Developmental Dynamics
- Deregulation of Transcription Factor Networks Driving Cell Plasticity and Metastasis in Pancreatic CancerRuthger van Roey, Thomas Brabletz, Marc P. Stemmler, Isabell Armstark · 2021 · Frontiers in Cell and Developmental Biology
- MNX1-HNF1B Axis Is Indispensable for Intraductal Papillary Mucinous Neoplasm LineagesHiroyuki Kato, Keisuke Tateishi, Hiroaki Fujiwara, Takuma Nakatsuka, Keisuke Yamamoto, Yotaro Kudo, Yoku Hayakawa, Hayato Nakagawa, Yasuo Tanaka, Hideaki Ijichi et al. · 2021 · Gastroenterology
- Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformationAn Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu, Julian A. Gingold, Ying Liu, Dandan Zhu, Chian‐Shiu Chien, Wei‐Chen Wang et al. · 2023 · Nature Communications
- NF-YC in glioma cell proliferation and tumor growth and its role as an independent predictor of patient survivalHua Lei Cui, Mingkun Zhang, Yanxia Wang, Yong Wang · 2016 · Neuroscience Letters
- A Driver Never Works Alone—Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human CancerMaria Grzes, Magdalena Oroń, Zuzanna Staszczak, Akanksha Jaiswar, Magdalena Nowak-Niezgoda, Dawid Walerych · 2020 · Cancers
- Dual Role of p73 in Cancer Microenvironment and DNA Damage ResponseJulian Markovich Rozenberg, Svetlana D. Zvereva, Alexandra A. Dalina, Igor Blatov, Ilya V. Zubarev, Daniil V. Luppov, Alexander Bessmertnyi, Alexander O. Romanishin, Lamak Alsoulaiman, Vadim Vladimirovich Kumeiko et al. · 2021 · Cells
- Histone deacetylases: A novel class of therapeutic targets for pancreatic cancerXue-Song Xiang, Pengcheng Li, Wenquan Wang, Liang Liu · 2022 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Transcriptome Analysis of Goat Mammary Gland Tissue Reveals the Adaptive Strategies and Molecular Mechanisms of Lactation and InvolutionRong Xuan, Jianmin Wang, Xiaodong Zhao, Qing Li, Yanyan Wang, Shanfeng Du, Qingling Duan, Yanfei Guo, Zhibin Ji, Tianle Chao · 2022 · International Journal of Molecular Sciences
- Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53Juliana Calheiros, Vincenzo Corbo, Lucı́lia Saraiva · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Genetic variants in the platelet‐derived growth factor subunit B gene associated with pancreatic cancer riskBensong Duan, Jiangfeng Hu, Hongliang Liu, Yanru Wang, Hongyu Li, Shun Liu, Jichun Xie, Kouros Owzar, James L. Abbruzzese, Herbert I. Hurwitz et al. · 2017 · International Journal of Cancer
- Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathwayMiao Sun, Gao Si, Hai-Shen Sun, Fu-Chun Si · 2018 · Biochemical and Biophysical Research Communications
- Early-Stage Metastasis Requires Mdm2 and Not p53 Gain of FunctionPaula M. Hauck, Eric R. Wolf, David J. Olivos, Christopher N. Batuello, Kyle C. McElyea, Ciarán P. McAtarsney, R. Michael Cournoyer, George Earl Sandusky, Lindsey D. Mayo · 2017 · Molecular Cancer Research
- Mutant p53 regulates Survivin to foster lung metastasisQiaosi Tang, Gizem Efe, Anna M. Chiarella, Jessica C. Leung, Maoting Chen, Taiji Yamazoe, Zhenyi Su, Jason Robert Pitarresi, Jinyang Li, Mirazul Islam et al. · 2021 · Genes & Development
- For robust big data analyses: a collection of 150 important pro-metastatic genesYan Mei, Jun-Ping Yang, Chao-Nan Qian · 2017 · 癌症:英文版
- Multimodal Therapies against Pancreatic Ductal Adenocarcinoma: A Review on Synergistic Approaches toward Ultimate Nanomedicine TreatmentsMarzia Conte, Valentina Cauda · 2022 · Advanced Therapeutics
- Pancreatic cancer‐derived small extracellular vesical ezrin activates fibroblasts to exacerbate cancer metastasis through STAT3 and YAP ‐1 signaling pathwaysYu‐Ting Chang, Hsuan‐Yu Peng, Chun‐Mei Hu, Sui-Chih Tien, Yi‐Ing Chen, Yung‐Ming Jeng, Ming‐Chu Chang · 2023 · Molecular Oncology
- Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesisDonglin Ding, Alexandra M. Blee, Jianong Zhang, Yunqian Pan, Nicole A. Becker, Louis James Maher, Rafael E. Jiménez, Liguo Wang, Haojie Huang · 2023 · Nature Communications
- Mechanism of apoptosis activation by Curcumin rescued mutant p53Y220C in human pancreatic cancerLakshay Malhotra, Saurabh Sharma, Gururao Hariprasad, Renu Dhingra, Vandana Mishra, Radhey Shyam Sharma, Punit Kaur, Abdul Samath Ethayathulla · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28Shujun Zhang, Peilong Li, Juan Li, Jie Gao, Qiuchen Qi, Guoying Dong, Xiaoyan Liu, Qinlian Jiao, Yunshan Wang, Lutao Du et al. · 2023 · British Journal of Cancer
- An unexpected inhibition of antiviral signaling by virus-encoded tumor suppressor p53 in pancreatic cancer cellsEric L. Hastie, Marcela P. Cataldi, Nury Steuerwald, Valery Z. Grdzelishvili · 2015 · Virology
- The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and InvasionPatricia Jaaks, Valentina D’Alessandro, Nicole Grob, Sina Büel, Katarina Hajdin, Beat W. Schäfer, Michele Bernasconi · 2016 · PLoS ONE
- Human pancreatic cancer progression: an anarchy among CCN-siblingsSushanta K. Banerjee, Gargi Maity, Inamul Haque, Arnab Ghosh, Sandipto Sarkar, Vijayalaxmi G. Gupta, Donald R. Campbell, Daniel D. Von Hoff, Snigdha Banerjee · 2016 · Journal of Cell Communication and Signaling
- Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in alleleJinghai Wu, Xin Liu, Sunayana G. Nayak, Jason Robert Pitarresi, Maria C. Cuitiño, Lianbo Yu, Blake Eason Hildreth, Katie Thies, Daniel J. Schilling, Soledad Fernández et al. · 2017 · PLoS ONE
- Targeting of promising transmembrane proteins for diagnosis and treatment of pancreatic ductal adenocarcinomaVida Mashayekhi, Orsola Mocellin, Marcel H.A.M. Fens, Gerard C. Krijger, Lodewijk A.A. Brosens, Sabrina Oliveira · 2021 · Theranostics
- Mutant p53-ENTPD5 control of the calnexin/calreticulin cycle: a druggable target for inhibiting integrin-α5-driven metastasisEvangelos Pavlakis, Michelle M. Neumann, Nastasja Merle, Ronja Wieboldt, Michael Wanzel, Viviane Ponath, Elke Pogge von Strandmann, Sabrina Elmshäuser, Thorsten Stiewe · 2023 · Journal of Experimental & Clinical Cancer Research
- Alpha-1-acid glycoprotein 1 is upregulated in pancreatic ductal adenocarcinoma and confers a poor prognosisQimin Zhou, Roland E. Andersson, Dingyuan Hu, Monika Posaric Bauden, Agata Sasor, Thomas Bygott, Krzysztof Pawłowski, Indira Plá, György Marko‐Varga, Daniel Ansari · 2019 · Translational research
- Protein Advanced Glycation End Products and Their Implications in Pancreatic CancerLakmini Kumari Senavirathna, Sheng Pan, Ru Chen · 2023 · Cancer Prevention Research
- Epigenetic control of pancreatic cancer metastasisLukas Krauß, Carolin Schneider, Elisabeth Heßmann, Dieter Saur, Günter Schneider · 2023 · Cancer and Metastasis Reviews
- Advances in understanding the molecular mechanism of pancreatic cancer metastasisYongxing Du, Ziwen Liu, Lei You, Wenming Wu, Yu-Pei Zhao · 2016 · Hepatobiliary & pancreatic diseases international
- Discovering key transcriptomic regulators in pancreatic ductal adenocarcinoma using Dirichlet process Gaussian mixture modelSk Md Mosaddek Hossain, Aanzil Akram Halsana, Lutfunnesa Khatun, Sumanta Ray, Anirban Mukhopadhyay · 2021 · Scientific Reports
- microRNAs: short non-coding bullets of gain of function mutant p53 proteinsSara Donzelli, Sabrina Strano, Giovanni Blandino · 2014 · Oncoscience
- Valosin-Containing Protein Stabilizes Mutant p53 to Promote Pancreatic Cancer GrowthJieqiong Wang, Yajie Chen, Canhua Huang, Qian Hao, Shelya X. Zeng, Sara Omari, Yu Zhang, Xiang Yu Zhou, Hua Lu · 2021 · Cancer Research
- TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDACMeena U. Rajagopal, Shivani Bansal, Prabhjit Kaur, Shreyans Kumar Jain, Tatiana Altadill, Charles P. Hinzman, Yaoxiang Li, Joanna Moulton, Baldev B. Singh, Sunil Bansal et al. · 2021 · Cancers
- From regulation to deregulation of p53 in hematologic malignancies: implications for diagnosis, prognosis and therapySeyed Esmaeil Ahmadi, Elahe Rahimian, Samira Rahimi, Bahman Zarandi, Mehran Bahraini, Maral Soleymani, Seyed Mehrab Safdari, Ashkan Shabannezhad, Niloofar Jaafari, Majid Safa · 2024 · Biomarker Research
- Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cellsMin Xu, Feifei Qi, Shaosen Zhang, Xuhui Ma, Shan Wang, Chunying Wang, Yan Fu, Yongzhang Luo · 2016 · Oncotarget
- Control of Nucleotide Metabolism Enables Mutant p53’s Oncogenic Gain-of-Function ActivityValentina A. Schmidt, Rachana Nagar, Luis A. Martinez · 2017 · International Journal of Molecular Sciences
- p53 mutations define the chromatin landscape to confer drug tolerance in pancreatic cancerCarlotta Zampieri, Emanuele Panatta, Vincenzo Corbo, Alessandro Mauriello, Gerry Melino, Ivano Amelio · 2021 · Molecular Oncology
- Immunotherapy in hepatocellular carcinoma: an overview of immune checkpoint inhibitors, drug resistance, and adverse effectsXuan-Yu Gu, Jin-Long Huo, Zhiyong Yu, Ji-Chang Jiang, Ya-Xuan Xu, Lijin Zhao · 2024 · ONCOLOGIE
- ErbB2 inhibition by lapatinib promotes degradation of mutant p53 protein in cancer cellsDun Li, Natalia D. Marchenko · 2016 · Oncotarget
- Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus CarcinomaAlbert S. Cornelius, Jessica M. Foley, Jeffrey P. Bond, Abhinav Beeravally Nagulapally, Julie Steinbrecher, William P.D. Hendricks, Maria E. Rich, Sangeeta Yendrembam, Genevieve Bergendahl, Jeffrey M. Trent et al. · 2017 · Frontiers in Pharmacology
- Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasivenessMaciej B. Olszewski, Magdalena Pruszko, Ewa B. Snaar-Jagalska, Maciej Żylicz, Maciej Żylicz · 2019 · International Journal of Oncology
- Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53Carla M. Borini Etichetti, Evelyn Arel Zalazar, Nabila Cocordano, Javier E. Girardini · 2020 · Frontiers in Oncology
- Chaperones and Ubiquitin Ligases Balance Mutant p53 Protein Stability in Esophageal and Other Digestive CancersMay San Martinho, Derek J. Nancarrow, Theodore Steven Lawrence, David G. Beer, Dipankar Ray · 2020 · Cellular and Molecular Gastroenterology and Hepatology
- Clinical Applications of Classical and Novel Biological Markers of Pancreatic CancerLeonel Pekarek, Oscar Fraile‐Μartinez, Cielo García Montero, Miguel A. Sáez, Ines Barquero-Pozanco, Laura del Hierro-Marlasca, Patricia De Castro-Martinez, Adoración Romero-Bazán, Miguel Ángel Álvarez-Mon, Jorge Monserrat et al. · 2022 · Cancers
- Ganetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent mannerEvguenia M. Alexandrova, Sulan Xu, Ute Martha Moll · 2017 · Cell Death and Disease
- Hallmarks of liver cancer: Therapeutic implicationsJosep Maria Llovet, Roser Pinyol, Silvia Affò, Mark M. Yarchoan, Gregory James Gores, Robin Kate Kelley, Scott W. Lowe, Daniela Sia, Augusto Villanueva · 2026 · Cell
- Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53Stephen Lee Abrams, Przemysław Duda, Shaw M. Akula, Linda S. Steelman, Matilde L. Follo, Lucio Cocco, Stefano Ratti, Alberto Maria Martelli, Giuseppe Montalto, Maria Rita Emma et al. · 2022 · Cells
- Role of Epigenetics in Pancreatic Ductal AdenocarcinomaSomnath Pandey, Vineet Kumar Gupta, Shweta Lavania · 2023 · Epigenomics
- The high expression instead of mutation of p53 is predictive of overall survival in patients with esophageal squamous‐cell carcinoma: a meta‐analysisZiran Zhao, Pan Wang, Yibo Gao, Jie He · 2016 · Cancer Medicine
- Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signalingEisuke Horigome, Michiru Fujieda, Tadashi Handa, Ayaka Katayama, Masashi Ito, Ami Ichihara, Daiki Tanaka, Navchaa Gombodorj, Shinji Yoshiyama, Arito Yamane et al. · 2018 · Oncotarget
- The Diverse Functions of Mutant 53, Its Family Members and Isoforms in CancerCallum Hall, Patricia A. J. Muller · 2019 · International Journal of Molecular Sciences
- Differentiating TP53 Mutation Status in Pancreatic Ductal Adenocarcinoma Using Multiparametric MRI-Derived RadiomicsJing Gao, Xiahan Chen, Xudong Li, Fei Miao, Weihuan Fang, Biao Li, Xiaohua Qian, Xiaozhu Lin · 2021 · Frontiers in Oncology
- A Novel Biomarker Panel Examining Response to Gemcitabine with or without Erlotinib for Pancreatic Cancer Therapy in NCIC Clinical Trials Group PA.3David Benjamin Shultz, Jonathan Pai, Wayland Chiu, Kendall Ng, Madeline G. Hellendag, Gregory M. Heestand, Daniel Tandel Chang, Dongsheng Tu, Malcolm J. Moore, Wendy R. Parulekar et al. · 2016 · PLoS ONE
- Decreased mean platelet volume predicts poor prognosis in patients with pancreatic cancerTakuki Yagyu, Hiroaki Saito, Teruhisa Sakamoto, Ei Uchinaka, Masaki Morimoto, Takehiko Hanaki, Joji Watanabe, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu et al. · 2021 · BMC Surgery
- The Multifaceted Role of p53 in Cancer Molecular Biology: Insights for Precision Diagnosis and Therapeutic BreakthroughsBolong Xu, Ayitila Maimaitijiang, Dawuti Nuerbiyamu, Zhengding Su, Wenfang Li · 2025 · Biomolecules
- PAI1 is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment with PIM Inhibitor AZD1208Sandra Muñoz-Galván, Maria Rivero, J. Peinado, Julia Martínez‐Pérez, MC Fernández-Fernández, María José Ortiz, José Manuel García-Heredia, Amancio Carnero · 2020 · Cells
- Commensal microbes and p53 in cancer progressionIvana Celardo, Gerry Melino, Ivano Amelio · 2020 · Biology Direct
- Bayesian Pathway Analysis of Cancer Microarray DataMelike Korucuoglu, Senol Isci, Arzucan Özgür, Hasan H. Otu · 2014 · PLoS ONE
- Gene Regulation by p53 in Human Cancer SystemSupratit Ghosh, Meghna Bhattacharjee, Nandan Kumar Jana · 2022 · Asian Pacific Journal of Cancer Biology
- TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastomaHaiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang · 2022 · BMC Genomic Data
- Identification of genes and pathways associated with pancreatic ductal adenocarcinoma by bioinformatics analysesJin Long, Zhongbo Zhang, Zhe Liu, Yuanhong Xu, Chunlin Ge · 2015 · Oncology Letters
- Integrative landscape of dysregulated signaling pathways of clinically distinct pancreatic cancer subtypesMusalula Sinkala, Nicola Mulder, Darren Patrick Martin · 2018 · Oncotarget
- p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein foldingOleg N. Timofeev, Thorsten Stiewe · 2017 · Molecular & Cellular Oncology
- Molecular Research in Pancreatic Cancer: Small Molecule Inhibitors, Their Mechanistic Pathways and BeyondShaila A. Shetu, Nneoma James, Gildardo Rivera, Debasish Bandyopadhyay · 2023 · Current Issues in Molecular Biology
- Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21Maria Mortoglou, Francesc Miralles, Rhys Richard Mould, Dipankar Sengupta, Pinar Uysal Onganer · 2023 · European Journal of Cell Biology