KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport

Cited by (246)

Items 201–246 of 246

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    Hui Zhong, Yanjun Zhang, Xiaobin Shan · 2018 · Journal of Biomolecular Structure and Dynamics
  2. Basal extrusion drives cell invasion and mechanical stripping of E-cadherin
    John Fadul, Gloria M. Slattum, Nadja M. Redd, Mauricio Franco Jin, Michael J. Redd, Stephan Daetwyler, Danielle S. Hedeen, Jan Huisken, Jody Rosenblatt · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Targeting PDE6D for inhibiting KRAS: A computational approach
    Ayooluwa Ilesanmi, Gbenga Dairo, Toheeb Adewale Balogun, Bibiire Awoyale · 2022 · ChemRxiv
  4. CRISPR/Cas9 Gene Editing of HeLa Cells to Tag Proteins with mNeonGreen
    Sachin Surve, Alexander D. Sorkin · 2022 · BIO-PROTOCOL
  5. KRAS Promoter Methylation Status and miR-18a-3p and miR-143 Expression in Patients With Wild-type KRAS Gene in Colorectal Cancer
    J A Herrera Pulido, Orlando Ricaurte Guerrero, Jinneth Acosta Forero, Pablo Moreno‐Acosta, Alfredo Ernesto Romero-Rojas, María Carolina Sanabria, Gustavo Hernández, Martha Lucía Serrano · 2022 · Cancer Diagnosis & Prognosis
  6. Identification of bioactive compounds from Vaccinium vitis-idaea L. (Lingonberry) as inhibitors for treating KRAS-associated cancer: a computational approach
    Ayooluwa Ilesanmi, Gbenga Dairo, Sofela Salimat, Damilola Samuel Bodun, Bibiire Awoyale, Toheeb Adewale Balogun · 2023 · In Silico Pharmacology
  7. Investigation of a Novel PDEδ Inhibitor Targeting K-Ras in Colorectal Cancer: An in Silico and Computer-Aided Drug Design Approach
    Mohammed Mouhcine, Imane Rahmoune, Houda Filali · 2025 · Journal of Drug Delivery and Therapeutics
  8. Transfiguring Novel Marine Natural Product as Oncogenic KRAS G12C Mutant Inhibitors via In-Silico and Computational Approaches
    Nausheen Nazir, Muhammad Husnain, Arbaz Waqar, Munazza Kanwal, Tariq A. Aziz, Nawal Al‐Hoshani, Rania Ali El Hadi Mohamed, Maher S. Alwethaynani, Fakhria A. Al‐Joufi, Reem Nabil Hassan · 2025 · Journal of Computational Biophysics and Chemistry
  9. The Spatial Organization of Ras Signaling
    Bjoern Papke, Malte Schmick, Nachiket Vartak, Philippe I. H. Bastiaens · 2014 · Springer eBooks
  10. Stability of the Phosphotriester PDE6D Inhibitors
    Petja Rosenqvist, Ahmed Sabt, Venera Dyunyasheva, Daniel Abankwa, Pasi Virta, Mikko Ora · 2021 · ChemistrySelect
  11. Membrane extraction by calmodulin underpins the disparate signalling of RalA and RalB
    Samuel G. Chamberlain, Darerca Owen, Helen R. Mott · 2022 · BioEssays
  12. Development of PD3 and PD3-B for PDEδ inhibition to modulate KRAS activity
    Jungeun Lee, Ho Jin Lee, Yeongcheol Lee, Bumhee Lim, Jongsik Gam, Dong‐Chan Oh, Jeeyeon Lee · 2022 · Journal of Enzyme Inhibition and Medicinal Chemistry
  13. Small-Molecule Inhibitors of Protein–Protein Interactions as Therapeutics
    Krishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi, Nupur Nagar · 2023 · Springer eBooks
  14. Understanding Ras Spatial Cycles Through Reaction-Diffusion Simulations
    Malte Schmick, Philippe I. H. Bastiaens · 2021 · Methods in molecular biology
  15. A synthetic morphogenic membrane system that responds with self-organized shape changes to local light cues
    Konstantin Gavriljuk, Bruno Scocozza, Farid Ghasemalizadeh, Akhilesh P. Nandan, Manuel Campos-Medina, Hans Seidel, Malte Schmick, Aneta Koseska, Philippe I. H. Bastiaens · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  16. A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95
    Kristen M. Rehl, Jayaraman Selvakumar, Don Hoang, Kuppuswamy Arumugam, Alemayehu Abebe Gorfe, Kwang‐Jin Cho · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  17. RAS G-domains fine-tune the sorting of phosphatidylserine acyl chains in the plasma membrane
    Neha Arora, Liang Hong, Yong Zhou · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  18. Oncogenic KRAS regulates secretion of extracellular vesicles and surface membrane charge via regulation of phosphatidylserine in pancreatic cancer
    Kshipra S. Kapoor, Xin Luo, Kaira A. Church, Martin M Bell, Bo Fan, Seoyun Kong, Elena V. Ramirez, Yilin Chen, Fernanda Grande Kugeratski, Sibani Lisa Biswal et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Report from the Third Annual Symposium of the RIKEN–Max Planck Joint Research Center for Systems Chemical Biology
    Andreas Brunschweiger · 2014 · ACS Chemical Biology
  20. Identifying Novel Inhibitors of Epithelial to Mesenchymal Transition (EMT) for Targeting Pancreatic Cancer Metastasis and Cancer Stem Cells
    Kishore Polireddy · 2015 · KU ScholarWorks (The University of Kansas)
  21. FUNCTIONAL ASYMMETRY OF THE IMMUNE CELL PLASMA MEMBRANE
    Eric Malmberg · 2017 · Digital Commons-TMC (Texas Medical Center)
  22. A Synthetic Morphogenic Perceptory Cell
    Konstantin Gavriljuk, Farid Ghasemalizadeh, Bruno Scocozza, Akhilesh P. Nandan, Hans Seidel, Malte Schmick, Aneta Koseska, Philippe I. H. Bastiaens · 2018 · SSRN Electronic Journal
  23. Ras and Ras Signaling as a Therapeutic Target in Cancer
    Bailee H. Sliker, Paul M. Campbell · 2021 · Elsevier eBooks
  24. Brain I3 Binding Protein regulates K-Ras4B membrane localization and signaling
    Ian P. McCabe, Huanqing Zhang, Jonathan A. Cooper, David L. Turner, Anne B. Vojtek · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Faculty Opinions recommendation of Coordination of Rheb lysosomal membrane interactions with mTORC1 activation.
    Paul A. Gleeson · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  26. A novel role for RASSF1A in the regulation of RAS activation.
    Desmond Harrell Stewart · 2020 · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville)
  27. Ds-SiFi: A Photo-Conversion-Based Approach to Quantify the Effective Diffusivity of Biomolecules in vivo
    Shiwei Ni, Xi Zhang, Minjie Zhang, Shengxi Yang, Caixi Gao, Xiaozhen He, Zhangming Yan, Zhirong Sun, Guolong Chen, Yufeng Yang · 2022 · SSRN Electronic Journal
  28. Modeling and Simulation of Lipid Membranes
    Marti, Jordi, Carles Calero · 2022 · MDPI eBooks
  29. S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi
    Daniel M. Williams, Andrew A. Peden · 2024 · eLife
  30. Detection and Quantitation of Endogenous Membrane-Bound RAS Proteins and KRAS Mutants in Cancer Cell Lines Using 1D-SDS-PAGE LC–MS2
    Jan A. Kaczmarczyk, Gordon Whiteley, Josip Blonder · 2024 · Methods in molecular biology
  31. S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi
    Daniel M. Williams, Andrew A. Peden · 2024 · eLife
  32. Pharmacologically active antibodies for treatment of cancer and pain
    Oscar Jungholm · 2025
  33. Prise en charge du cancer pulmonaire non à petites cellules avec mutation de KRAS
    Ali Chour, Claire Lafitte, Maxime Boussageon, Thomas Pierret, M. Duruisseaux · 2025 · Revue des Maladies Respiratoires Actualités
  34. Mécanismes moléculaires et cellulaires de formation et de dissolution des « processing bodies » en conditions physiologiques et physiopathologiques
    Olivia Vidal-Cruchez · 2021 · theses.fr (ABES)
  35. Posttranslational modifications of RAS: few pockets but many bumps
    Mercedes Fissore-O'Leary, Mark R. Philips · 2026 · Biological Chemistry
  36. The role of PDE6D in trafficking KRAS
    Luna Van Nimmen, Hanne Peeters, Shehab Ismail · 2026 · Biological Chemistry
  37. Reversible Opto-Chemical activation of KRASG12V signaling with near single-cell precision
    Luis Manuel Muñoz-Nava, Maria Bespalova, Mario O. Caracci, Kitso Ata Kewagamang, Birga Soetje, Sabrina Seidler, Kirsten Michel, Holger Vogel, Janicke Maerz, Philippe I. H. Bastiaens · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Regulation of de- and reciliation by KRAS during muscle cell differentiation
    Rohan Chippalkatti, Bianca Parisi, Elisabeth Schaffner‐Reckinger, Christina Laurini, Atanasio Gómez‐Mulas, Zoe Geimer, Daniel Abankwa · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Oncogenic KRAS Regulates Secretion of Extracellular Vesicles and Surface Membrane Charge via Regulation of Phosphatidylserine in Pancreatic Cancer
    Paul A. Spezza, Kshipra S. Kapoor, Beatrice Pforr, Xin Luo, Kaira A. Church, Martin M. Bell, Bo Fan, Seoyun Kong, Elena V. Ramirez, Yilin Chen et al. · 2026 · ACS Nano
  40. Regulation of Membrane Association and Downstream Effector Interaction of K-Ras by Its Hypervariable Region
    Anda Trifan, Hossein Omidi-Ardali, Josh V. Vermaas, Till Rudack, Emad Tajkhorshid · 2026 · Membranes
  41. BindingDB Entry 50021942: An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth.
    BindingDB · 2025 · UC San Diego
  42. BindingDB Entry 50010796: Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer.
    BindingDB · 2021 · UC San Diego
  43. BindingDB Entry 50000629: Discovery of Novel KRAS-PDEδ Inhibitors by Fragment-Based Drug Design.
    BindingDB · 2019 · UC San Diego
  44. BindingDB Entry 50023610: Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells.
    BindingDB · 2026 · UC San Diego
  45. BindingDB Entry 50000422: Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors.
    BindingDB · 2019 · UC San Diego
  46. BindingDB Entry 50020071: Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC).
    BindingDB · 2024 · UC San Diego