Editing DNA Methylation in the Mammalian Genome

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Items 901–1,000 of 1,000

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  3. Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons
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  4. Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes
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  5. Identification of DNA Methylation Signatures for Diagnosis of Lung Adenocarcinoma
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  6. Human development, heredity and evolution
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  7. Boosting, Not Breaking: CRISPR Activators Treat Disease Models
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  8. Key to Delivery: The (Epi-)genome Editing Vector Toolbox
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  9. Current trends in site and target specific delivery of nanomedicine for gene therapy
    Arunachalam Muthuraman, Seema Mehdi, Narahari Rishitha · 2019 · Elsevier eBooks
  10. DNA Methylation and Carcinogenesis: Current and Future Perspectives
    Vibha Patil, Zdenko Herceg · 2019 · Springer eBooks
  11. Zfp189 Mediates Stress Resilience Through a CREB-Regulated Transcriptional Network in Prefrontal Cortex
    Zachary S. Lorsch, Peter J. Hamilton, Aarthi Ramakrishnan, Eric M. Parise, William J. Wright, Marine Salery, Ashley E. Lepack, Philipp Mews, Orna Issler, Andrew Thomas McKenzie et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Transgenic mice for in vivo epigenome editing with CRISPR-based systems
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  18. Unraveling the interplay of DNA methylation and chromosome organization
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  19. Long Single‐Stranded DNA with Site‐Specific Modifications to Enable Single‐Base‐Resolution Epigenetics
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  22. Next generation technologies for CRISPR-based epigenome and transcriptional modulation
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  26. Epigenetic Tools in Chronic Pain Studies
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  27. CRISPR-Cas orthologs and variants
    Margaret E. Scollan · 2021 · Elsevier eBooks
  28. Editing the Epigenome in Neurodegenerative Diseases
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  30. Nucleic Acid Editing
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  32. CRISPR/dCas9-Mediated DNA Methylation Editing on emx2 in Chinese Tongue Sole (Cynoglossus semilaevis) Testis Cells
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  34. Generation of an inducible dCas9-SAM human PSC line for endogenous gene activation
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  35. DNA methylation in the association between pesticide exposures and type 2 diabetes
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  42. A protocol to build microRNA-inducible CRISPR-Cas9 platform
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  43. DNA Methylation in Multiple Sclerosis
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  44. CRISPR/Cas9 technologies in epigenetics research
    John M. Schoelz, Nicole C. Riddle · 2020 · Elsevier eBooks
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  46. Functional genomics of psychiatric disease risk using genome engineering
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  47. Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
    Julia B. Carleton, Kristofer C. Berrett, Jason Gertz · 2018 · Journal of Visualized Experiments
  48. Fragile X Syndrome Patient–Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes
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  49. The transcription activity of OTX2 on p16 expression is significantly blocked by methylation of CpG shore in non-promoter of lung cancer cell lines
    Honghao Peng, Wenfan Fu, Chong Hyun Chang, Huan Gao, Qianmei He, Ziqi Liu, Mengxing Cui, Han Wang, Yongjiang Yu, Yonghui Wu et al. · 2023 · Translational Cancer Research
  50. CRISPR/Cas9 Editing in Induced Pluripotent Stem Cells: A Way Forward for Treating Cystic Fibrosis?
    Erik J. Quiroz, Amy L. Ryan · 2019 · Springer eBooks
  51. Nuclease-Deficient Clustered Regularly Interspaced Short Palindromic Repeat-Based Approaches for In Vitro and In Vivo Gene Activation
    Angela Lek, Kaiyue Ma, Keryn G. Woodman, Monkol Lek · 2021 · Human Gene Therapy
  52. Epigenetic Epidemiology of Obesity and Type 2 Diabetes
    Charlotte Ling, Sabrina Ruhrmann, Johanna Säll, Karl Bacos, Tina Rönn · 2022 · Springer eBooks
  53. Inducible, tunable and multiplex human gene regulation using CRISPR-Cpf1-based transcription factors
    Yu Gyoung Tak, Benjamin P. Kleinstiver, James K. Nuñez, Jonathan Y. Hsu, Jingyi Gong, Jonathan S. Weissman, J. Keith Joung · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  54. The new normal of structure/function studies in the era of CRISPR/Cas9
    Glennis A. Logsdon, Ben E. Black · 2018 · Biochemical Journal
  55. CRISPR Toolbox for Mammalian Cell Engineering
    Daria Sergeeva, Karen Julie la Cour Karottki, Jae Seong Lee, Helene Faustrup Kildegaard · 2019 · Wiley eBooks
  56. Genome Variation, the Epigenome and Cellular Phenotypes
    Martina Baumann, Gerald Klanert, Sabine Vcelar, Marcus Weinguny, Nicolas Marx, Nicole Borth · 2019 · Wiley eBooks
  57. Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops
    João C. Sabino, Madalena R. de Almeida, Patrícia L. Abreu, Ana M. Ferreira, Marco M. Domingues, Nuno C. Santos, Claus M. Azzalin, Ana Rita Grosso, Sérgio F. de Almeida · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  58. Comparative Analysis and Rational Design of dCas9-VP64 Variants for CRISPR Activation
    Kohei Omachi, Jeffrey H. Miner · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Applications of CRISPRi and CRISPRa in Drug Discovery
    Luke A. Gilbert · 2022 · Wiley eBooks
  60. Hit-and-run silencing of endogenous DUX4 by targeting DNA hypomethylation on D4Z4 repeats in facioscapulohumeral muscular dystrophy
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  61. Epigenetic Editing: Repurposing for Rescue
    Hari Singh · 2018 · Trends in Biochemical Sciences
  62. Development of a new in vitro assay system for evaluating the effects of chemicals on DNA methylation
    Maky Ideta-Otsuka, Misato Miyai, Naoki Yamamoto, Ayaka Tsuchimoto, Hideki Tamura, Kentaro Tanemura, Makoto Shibutani, Katsuhide Igarashi · 2021 · The Journal of Toxicological Sciences
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  64. Modular cytosine base editing promotes epigenomic and genomic modifications
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  68. Expression and purification of cell-penetrating Cas9 and Cas12a enzymes for peptide-assisted genome editing
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  70. Methylation of the telomerase gene promoter region in umbilical cord blood of patients with gestational diabetes mellitus is associated with decreased telomerase expression levels and shortened telomere length
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  71. Development and application of epigenome editors
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  87. Enhanced muscle growth via DNA methylation editing of mstnb exon in zebrafish
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  98. Turning the corner from observation to intervention in human genetics
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