Metabolic adaptation establishes disease tolerance to sepsis

Cited by (283)

Items 101–200 of 283

1. Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling
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2. Long noncoding RNA GSEC promotes neutrophil inflammatory activation by supporting PFKFB3-involved glycolytic metabolism in sepsis
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3. Pterostilbene 4 ′‐β‐Glucoside Attenuates LPS‐Induced Acute Lung Injury via Induction of Heme Oxygenase‐1
   Jeongmin Park, Yingqing Chen, Min Zheng, Jinhyun Ryu, Gyeong Jae Cho, Young‐Joon Surh, Daisuke Sato, Hiroki Hamada, Stefan W. Ryter, Uh‐Hyun Kim et al. · 2018 · Oxidative Medicine and Cellular Longevity
4. Alleviating protein-condensation-associated damage at the endoplasmic reticulum enhances plant disease tolerance
   Zhijuan Tang, Shaosong Shi, Ruixia Niu, Yulu Zhou, Zhao Wang, Rongrong Fu, Rui Mou, Suming Chen, Pingtao Ding, Guoyong Xu · 2024 · Cell Host & Microbe
5. H2 Protects Against Lipopolysaccharide-Induced Cardiac Dysfunction via Blocking TLR4-Mediated Cytokines Expression
   Sihua Tan, Zhiyuan Long, Xiangping Hou · 2019 · Frontiers in Pharmacology
6. Microphysiological systems meet hiPSC technology – New tools for disease modeling of liver infections in basic research and drug development
   Martin Raasch, Enrico Fritsche, Armin Kurtz, Michael W Bauer, Alexander Sandy Mosig · 2018 · Advanced Drug Delivery Reviews
7. Update on diagnosis and management of sepsis in cirrhosis: Current advances
   Cyriac Abby Philips, Rizwan Ahamed, S Rajesh, Tom George, Meera Mohanan, Philip Augustine · 2020 · World Journal of Hepatology
8. Impact of bacterial infections on erythropoiesis
   Lara Valente de Souza, Alexander Hoffmann, Günter Weiß · 2020 · Expert Review of Anti-infective Therapy
9. Ferritin H deficiency deteriorates cellular iron handling and worsens Salmonella typhimurium infection by triggering hyperinflammation
   David Haschka, Piotr Tymoszuk, Verena Petzer, Richard Hilbe, Simon Heeke, Stefanie Dichtl, Sergej Skvortsov, Egon Demetz, Sylvia Berger, Markus Seifert et al. · 2021 · JCI Insight
10. Clinical characteristics and construction of a predictive model for patients with sepsis related liver injury
    Tonghui Xie, Qi Xin, Xirong Cao, Rui Chen, Hong Ren, Chang Liu, Jingyao Zhang · 2022 · Clinica Chimica Acta
11. Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis
    Yvonn Heun, Joachim Pircher, Thomas Czermak, Philipp Blüm, Georg Hupel, Monica J. Bohmer, Bjoern F. Kraemer, Kristin Pogoda, Alexander Pfeifer, Markus Woernle et al. · 2019 · EBioMedicine
12. Targeted delivery of a phosphoinositide 3‐kinase γ inhibitor to restore organ function in sepsis
    Adrian Tibor Press, Petra Babic, Bianca Hoffmann, Tina Müller, Wanling Foo, Walter Hauswald, Jovana Benecke, Martina Beretta, Zoltán Cseresnyés, Stephanie Hoeppener et al. · 2021 · EMBO Molecular Medicine
13. Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis
    K. L. C. da Silva, A. P. Camacho, Francine Cappa Mittestainer, Bruno M. Carvalho, Andrey Santos, Dioze Guadagnini, Alexandre Gabarra Oliveira, Mário J.A. Saad · 2018 · Journal of Inflammation
14. Ferritin heavy chain supports stability and function of the regulatory T cell lineage
    Qian Wu, Ana Rita Carlos, Faouzi Braza, Marie‐Louise Bergman, Jamil Zola Kitoko, Patricia Bastos-Amador, Eloy Cuadrado, Rui Martins, Bruna Sabino Pinho de Oliveira, Vera C. Martins et al. · 2024 · The EMBO Journal
15. The flux of energy in critical illness and the obesity paradox
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16. The liver-gut-axis: initiator and responder to sepsis
    Michael Bauer · 2022 · Current Opinion in Critical Care
17. Hormesis and Defense of Infectious Disease
    Sebastian Weis, Ignacio Rubio, Kristin Ludwig, Cynthia Weigel, Elisa Jentho · 2017 · International Journal of Molecular Sciences
18. Sepsis, pyruvate, and mitochondria energy supply chain shortage
    Charles E. McCall, Xuewei Zhu, Manal Zabalawi, David L. Long, Matthew A. Quinn, Barbara K. Yoza, Peter W. Stacpoole, Vidula Vachharajani · 2022 · Journal of Leukocyte Biology
19. Challenges in Exploiting Human H Ferritin Nanoparticles for Drug Delivery: Navigating Physiological Constraints
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20. Cross-Talk Between Iron and Glucose Metabolism in the Establishment of Disease Tolerance
    Ana Rita Carlos, Sebastian Weis, Miguel Parreira Soares · 2018 · Frontiers in Immunology
21. The role of heme in sepsis induced Kupffer cell PANoptosis and senescence
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22. Understanding metabolic resilience by unraveling temporal dynamics of cellular responses
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23. Interleukin‐5 deletion promotes sepsis‐induced M1 macrophage differentiation, deteriorates cardiac dysfunction, and exacerbates cardiac injury via the NF‐κB p65 pathway in mice
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24. Leukocyte Activation Profile Assessed by Raman Spectroscopy Helps Diagnosing Infection and Sepsis
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25. Gut Microbiota and Liver Dysfunction in Sepsis: The Role of Inflammatory Mediators and Therapeutic Approaches
    Aqsa Shahid, Stephen T. Chambers, Amy Scott-Thomas, Madhav Bhatia · 2024 · International Journal of Molecular Sciences
26. Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia
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27. Neuroimmune modulation by tryptophan derivatives in neurological and inflammatory disorders
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28. Regulation of Monocyte-Macrophage Responses in Cirrhosis—Role of Innate Immune Programming and Checkpoint Receptors
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29. Metabolic homeostasis in fungal infections from the perspective of pathogens, immune cells, and whole-body systems
    Harshini Weerasinghe, Helen Stölting, Adam J. Rose, Ana Traven · 2024 · Microbiology and Molecular Biology Reviews
30. Hormesis as an adaptive response to infection
    Michael W Bauer, Maria Ermolaeva, Mervyn Singer, Reinhard Wetzker, Miguel Parreira Soares · 2024 · Trends in Molecular Medicine
31. Erythrocyte degradation, metabolism, secretion, and communication with immune cells in the blood during sepsis
    Chih-Yu Chan, Ching‐Feng Cheng, Hao‐Ai Shui, Hui‐Chen Ku, Wen‐Lin Su · 2021 · Tzu Chi Medical Journal
32. Biochemical Analysis of Leukocytes after In Vitro and In Vivo Activation with Bacterial and Fungal Pathogens Using Raman Spectroscopy
    Aikaterini C. Pistiki, Anuradha Ramoji, Oleg Ryabchykov, Daniel O. Thomas-Rüddel, Adrian Tibor Press, Oliwia Makarewicz, Evangelos J. Giamarellos‐Bourboulis, Michael W Bauer, Thomas Wilhelm Bocklitz, Jürgen Popp et al. · 2021 · International Journal of Molecular Sciences
33. Immunomodulatory activity of hyaluronidase is associated with metabolic adaptations during acute inflammation
    Priscilla Aparecida Tártari Pereira, Claudia Silva Bitencourt, Mouzarllem Barros Reis, Fabiani Gai Frantz, Carlos A. Sorgi, Camila Oliveira Silva Souza, Célio Lopes Silva, Luiz Gustavo Gardinassi, Lúcia Helena Faccioli · 2019 · Inflammation Research
34. A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection
    Susan Westfall, Maria Elena Gentile, Tayla M. Olsen, Danielle Karo‐Atar, Andrei Bogza, Franziska Röstel, Ryan D. Pardy, Giordano Mandato, Ghislaine Fontès, De’Broski R. Herbert et al. · 2025 · Cell
35. Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis
    Brooks P. Leitner, Won Dong Lee, Wanling Zhu, Xinyi Zhang, Rafael Calais Gaspar, Zongyu Li, Joshua D. Rabinowitz, Rachel J. Perry · 2023 · PLoS ONE
36. The Mechanisms of Action of Hyperbaric Oxygen in Restoring Host Homeostasis during Sepsis
    Julie Vinkel, Bjoern Arenkiel, Ole Hyldegaard · 2023 · Biomolecules
37. The small heat shock protein HSPB1 protects mice from sepsis
    Elise R. Breed, Carolyn A. Hilliard, Benyam P. Yoseph, Rohit Mittal, Zhe Liang, Ching‐Wen Chen, Eileen M. Burd, Luke Packard Brewster, Laura Hansen, Rudolph L. Gleason et al. · 2018 · Scientific Reports
38. Sepsis‐associated hypoglycemia on admission is associated with increased mortality in intensive care unit patients
    Yumi Mitsuyama, Kentaro Shimizu, Sho Komukai, Atsushi Hirayama, Ryosuke Takegawa, Takeshi Ebihara, Tetsuhisa Kitamura, Hiroshi Ogura, Takeshi Shimazu · 2022 · Acute Medicine & Surgery
39. Defense strategies for plant health: Disease resistance and tolerance
    Zhijuan Tang, Rui Mou, Guoyong Xu · 2025 · The Plant Cell
40. Nutrition and infection
    G. Weiss · 2017 · Clinical Microbiology and Infection
41. Omics analysis revealed the possible mechanism of streptococcus disease outbreak in tilapia under high temperature
    Zaoya Zhao, Qianxing Zou, Shuyu Han · 2023 · Fish & Shellfish Immunology
42. Cellular and Exosomal Regulations of Sepsis-Induced Metabolic Alterations
    Michael Gyasi Appiah, Eun Jeong Park, Yuichi Akama, Yuki Nakamori, Eiji Kawamoto, Arong Gaowa, Motomu Shimaoka · 2021 · International Journal of Molecular Sciences
43. Circadian Rhythms in Bacterial Sepsis Pathology: What We Know and What We Should Know
    Malena Lis Mul Fedele, Camila Agustina Senna, Ignacio Aiello, Diego Andres Golombek, Natalia Paladino · 2021 · Frontiers in Cellular and Infection Microbiology
44. Impact of Chronic Infection on Resistance and Tolerance to Secondary Infection in Drosophila melanogaster
    Abigail M. Wukitch, Madyline M. Lawrence, Francesco P. Satriale, Alexa Patel, Grace M. Ginder, E. van Beek, Owais Gilani, Moria C. Chambers · 2023 · Infection and Immunity
45. Beyond tug-of-war: Iron metabolism in cooperative host–microbe interactions
    Grischa Y. Chen, Janelle S. Ayres · 2020 · PLoS Pathogens
46. Association of Serum Ferritin Levels and Methylprednisolone Treatment With Outcomes in Nonintubated Patients With Severe COVID-19 Pneumonia
    Aikaterini Papamanoli, Andreas P. Kalogeropoulos, Jessica Hotelling, Jeanwoo Yoo, Prabhjot K. Grewal, William Predun, Robin Jacob, Kerry Cao, Luis A. Marcos, Hal A. Skopicki · 2021 · JAMA Network Open
47. Inflammatory liver diseases and susceptibility to sepsis
    Hong Lü · 2024 · Clinical Science
48. Abnormal ferritin levels predict development of poor outcomes in cirrhotic outpatients: a cohort study
    Dávid Tornai, Péter Antal‐Szalmás, Tamás Tornai, Mária Papp, István Tornai, Nóra Sipeki, Tamás Janka, Boglárka Balogh, Zsuzsanna Vitális · 2021 · BMC Gastroenterology
49. TOR signalling is required for host lipid metabolic remodelling and survival following enteric infection in Drosophila
    Rujuta Deshpande, Byoungchun Lee, Yuemeng Qiao, Savraj Grewal · 2022 · Disease Models & Mechanisms
50. The epigenetic regulator G9a attenuates stress-induced resistance and metabolic transcriptional programs across different stressors and species
    Human Riahi, Michaela Fencková, Kayla J. Goruk, Annette Schenck, Jamie M. Kramer · 2021 · BMC Biology
51. Hypothyroidism confers tolerance to cerebral malaria
    Diego Rodríguez-Muñoz, Ángela Sánchez, Susana Pérez-Benavente, Constanza Contreras‐Jurado, Ana Montero‐Pedrazuela, Marta Toledo-Castillo, María Gutiérrez-Hernández, Raquel Rodrigues‐Díez, Cintia Folgueira, Ana María Briones et al. · 2022 · Science Advances
52. Low-dose deoxynivalenol exposure triggers hepatic excessive ferritinophagy and mitophagy mitigated by hesperidin modulated O-GlcNAcylation
    Hao Chen, Xintong Zhou, Jun Ma · 2024 · Journal of Hazardous Materials
53. Moderate glucose supply reduces hemolysis during systemic inflammation
    Johannes Jägers, Stephan Brauckmann, Michael Kirsch, Katharina Effenberger‐Neidnicht · 2018 · Journal of Inflammation Research
54. Enteral vs. parenteral nutrition in septic shock: are they equivalent?
    Matthias Lindner, Wolfgang H. Hartl, Gunnar Elke · 2019 · Current Opinion in Critical Care
55. Sepsis 2019 – New Trends and Their Implications for Multiple Trauma Patients
    Petra Dickmann, Michael W Bauer · 2019 · Zeitschrift für Orthopädie und Unfallchirurgie
56. Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
    Linlin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael W Bauer, Sebastian Weis, Mervyn Singer, Roman A. Lukaszewski, Gianni Panagiotou · 2025 · Advanced Science
57. A metabolite-based resistance mechanism against malaria
    Ana Leonor Figueiredo, Sharad Rastogi, Susana Ramos, Fátima Nogueira, Katherine A. de Villiers, António G. G. Sousa, Lasse Votborg-Novél, Cäcilie von Wedel, Pinkus Tober‐Lau, Elisa Jentho et al. · 2025 · Science
58. Update in Hyperferritinemic Syndromes: Recognition and Management - A Scoping Review
    Athanasios Vassilopoulos, Winston L. McCormick, Alisha Lakhani · 2022 · Journal of Brown Hospital Medicine
59. Disease tolerance: a protective mechanism of lung infections
    Jianqiao Xu, Nan Xiao, Dongsheng Zhou, Lixin Xie · 2023 · Frontiers in Cellular and Infection Microbiology
60. Iron homeostasis is altered in response to hypoxia and hypothermic preconditioning in brain glial cells
    Arzu Aral, Mehmet Ali Ergün, Ayşe Başak Engin, Alp Özgün Börcek, Hayrünnisa Bolay · 2020 · TURKISH JOURNAL OF MEDICAL SCIENCES
61. Critical Roles of Endogenous Glucocorticoids for Disease Tolerance in Malaria
    Leen Vandermosten, Ilse Vanhorebeek, Karolien De Bosscher, Ghislain Opdenakker, Philippe E. Van den Steen · 2019 · Trends in Parasitology
62. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury
    Michelle M. Lissner, Katherine Cumnock, Nicole M. Davis, José G. Vilches-Moure, Priyanka Basak, Daniel J. Navarrete, Jessica A. Allen, David S. Schneider · 2020 · eLife
63. What’s new in intensive care: disease tolerance
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64. Alzheimer’s Disease: Protective Effects of Mycobacterium vaccae, a Soil-Derived Mycobacterium with Anti-Inflammatory and Anti-Tubercular Properties, on the Proteomic Profiles of Plasma and Cerebrospinal Fluid in Rats
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65. Advances in sepsis research: Insights into signaling pathways, organ failure, and emerging intervention strategies
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66. A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance
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67. Heme induces innate immune memory
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68. The Systemic Inflammatory Response Syndrome and Predictors of Infection and Mortality in 1068 Critically Ill Newborn Foals
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69. Mechanisms underlying the therapeutic effects of 4-octyl itaconate in treating sepsis based on network pharmacology and molecular docking
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70. A case of hypercalcemia because of adrenal insufficiency induced by glucocorticoid withdrawal in a patient undergoing hemodialysis
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71. Murine Pancreatic Cancer Alters T Cell Activation and Apoptosis and Worsens Survival After Cecal Ligation and Puncture
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72. Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?
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73. Association of whole blood metals/metalloids with severity in sepsis patients: A prospective, single-center, pilot study
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74. TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22
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75. Loss of FTH1 Induces Ferritinophagy‐Mediated Ferroptosis in Anaemia of Myelodysplastic Syndromes
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76. Integrated control of leukocyte compartments as a feature of adaptive physiology
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77. Biological and clinical implications of a model of surveillance immunity
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78. Cardiomyocyte mitochondrial mono-ADP-ribosylation dictates cardiac tolerance to sepsis by configuring bioenergetic reserve in male mice
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79. GePI : large-scale text mining, customized retrieval and flexible filtering of gene/protein interactions
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80. Enhanced insulin signaling and its downstream effects in iron-overloaded primary hepatocytes from hepcidin knock-out mice
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81. Cold Exposure Protects from Neuroinflammation Through Immunologic Reprogramming
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82. Liver as a key organ for systemic antimicrobial defense
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83. Branched chain amino acids prime metabolic inflammation
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84. Infection-induced glucose starvation triggers NINJ1-dependent macrophage lysis and Candida escape
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85. Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits
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86. Informative Subtyping of Patients with Sepsis
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87. Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis
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88. Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study
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89. Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice
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90. Disease Tolerance: Linking Sickness Behaviours to Metabolism Helps Mitigate Malaria
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91. The value of neutrophil gelatinase-associated lipocalin and citrullinated alpha enolase peptide-1 antibody in diagnosis, classification, and prognosis for patients with sepsis
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92. Measuring signatures of host resistance, disease tolerance, and damage in human sepsis: a prospective cohort study
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93. 9th International Congress “Sepsis and Multiorgan Dysfunction”
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95. The association between hypoglycemia and mortality in sepsis and septic shock: A systematic review and meta-analysis
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96. The cytochrome P4501A1 (CYP1A1) inhibitor bergamottin enhances host tolerance to multidrug-resistant Vibrio vulnificus infection
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97. Neue Definitionen der Sepsis
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98. Urosepsis
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