Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Mitroulis, Ioannis, Ruppova, Klara, Wang, Baomei, Chen, Lan-Sun, Grzybek, Michal, Grinenko, Tatyana, Eugster, Anne, Troullinaki, Maria +20 more·2018·Cell

DOI 10.1016/j.cell.2017.11.034

Cited by (1,000)

Items 701–800 of 1,000

Pyrin Inflammasome Activation Abrogates Interleukin‐1 Receptor Antagonist, Suggesting a New Mechanism Underlying Familial Mediterranean Fever Pathogenesis
Sussi Bagge Mortensen, Ann‐Brit Eg Hansen, Trine Hyrup Mogensen, Marianne Antonius Jakobsen, Hans Christian Beck, Eva Bang Harvald, Kate Lykke Lambertsen, Işık Somuncu Johansen, Ditte Caroline Andersen · 2021 · Arthritis & Rheumatology
Trained immunity in the mucosal diseases
Dou Yu, Jiaqi Zhang, Shuo Wang · 2021 · WIREs Mechanisms of Disease
Trained immunity against diseases in domestic animals
Miriam Angulo, Carlos Angulo · 2022 · Acta Tropica
Oral administration of Euglena gracilis paramylon ameliorates chemotherapy-induced leukocytopenia and gut dysbiosis in mice
Youngju Song, Ho Cheol Shin, Hanary Geby Jessica Sianipar, Ji Yun Park, Mi‐Gi Lee, Jihye Hah, Hong Shik Park, Hyun Jeong Lee, Sukchan Lee, Hee Gon Kang · 2022 · International Journal of Biological Macromolecules
Trained Immunity-Based Vaccines: A Ready-to-Act Strategy to Tackle Viral Outbreaks
Laura Conejero, Paula Saz-Leal, José Luis Subiza · 2022 · IntechOpen eBooks
The future clinical implications of trained immunity
Valentin Nica, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten · 2022 · Expert Review of Clinical Immunology
Trained immunity as a possible newcomer in autoinflammatory and autoimmune diseases pathophysiology
Anne‐Sophie Beignon, Caroline Galeotti, Mickaël Mathieu Ménager, Adrien Schvartz · 2023 · Frontiers in Medicine
Are there differences in immune responses following delivery of vaccines through acutely or chronically sun‐exposed compared with sun‐unexposed skin?
Prue H. Hart, Mary Norval · 2019 · Immunology
Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19
Greg Maguire · 2021 · Communicative & Integrative Biology
Statins as Adjunctive Therapy Against Tuberculosis (TB): The Balance Between Statin-Induced Anti-TB Effect and Trained Immunity Suppression
Zhidong Hu, Douglas Bruce Lowrie, Xiao‐Yong Fan · 2019 · The Journal of Infectious Diseases
Trained immunity: a revolutionary immunotherapeutic approach
Md. Salauddin, Sabuj Kanti Nath, Sukumar Saha, Qingcong Zheng, Chunfu Zheng, Md. Golzar Hossain · 2024 · Animal Diseases
Integrated control of leukocyte compartments as a feature of adaptive physiology
Nikolai Jaschke, Andrew Wang · 2025 · Immunity
M28 family peptidase derived from Peribacillus frigoritolerans initiates trained immunity to prevent MRSA via the complosome-phosphatidylcholine axis
Cheng‐Kai Zhou, Zhenzhen Liu, Zi-Ran Peng, Xue-Yue Luo, Xiaomei Zhang, Jian Gang Zhang, Liang Zhang, Wei Chen, Yongjun Yang · 2025 · Gut Microbes
Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis
Alessia Provera, N. N. Ramavath, L. L. Gadipudi, C. Vecchio, M. Caputo, A. Antonioli, S. Tini, A. N. Sheferaw, S. Reano, N. Filigheddu et al. · 2025 · Frontiers in Immunology
Targeting alveolar macrophages in tuberculosis: Exploiting trained immunity for novel therapeutic approaches
Huilin Fang, Yan Xiong, Beibei Fu, Haibo Wu · 2025 · International Immunopharmacology
The significance of trained immunity in cancer
Junxing Qu, Xinya Guo, Xinru Wang, Huiwen Meng, Peizhi Li, Zhiheng Sun · 2025 · Frontiers in Immunology
Propagation of monocyte exhaustion memory and underlying mechanisms
Jing Wang, Blake A. Caldwell, Yajun Wu, Babak Razani, Liwu Li · 2025 · Cell Communication and Signaling
Trained Immunity in Interorgan Communication and Vascular Inflammation
Arthur Liesz · 2026 · Arteriosclerosis Thrombosis and Vascular Biology
TRAINED IMMUNITY: A POTENTIAL APPROACH FOR IMPROVING HOST IMMUNITY IN NEONATAL SEPSIS
Valerie E. Polcz, Jaimar C. Rincon, Russell B. Hawkins, Evan L. Barrios, Philip Alexander Efron, Lyle L. Moldawer, Shawn D. Larson · 2022 · Shock
Negative Regulation of Innate Immune Signaling by Components of the Button Mushroom Agaricus bisporus
Michele O'Sullivan, Elaine Dempsey, Sarah Case, Emer E. Hackett, Anna E. Ledwith, Hannah Prendeville, Tara O'Brien, Faye Lewis, Dearbhla M Murphy, Supriya Yadav et al. · 2023 · Molecular Nutrition & Food Research
Re‐recognition of innate immune memory as an integrated multidimensional concept
Chang Tang, Shoichiro Kurata, Naoyuki Fuse · 2023 · Microbiology and Immunology
Impact of Oil-in-Water Adjuvanted β-Glucan on Innate Immune Memory in Piglets
Razieh Ardali, Obdulio García-Nicolás, Catherine Ollagnier, José María Sánchez‐Carvajal, Maria Levy, Pauline Yvernault, Francisco de Aboim Borges Fialho de Brito, Artur Summerfield · 2024 · Vaccines
Bletilla striata polysaccharide-mediated trained immunity drives the hematopoietic progenitors’ expansion and myelopoiesis
Jiangtao Zhang, Chao Zhong, Lanying Chen, Yingying Luo, Le Tang, Jing Yang, Jing Jia, Xin-Xu Xie, Peng Liu, Jun Yu et al. · 2024 · International Immunopharmacology
Trained immunity and cardiovascular disease: is it time for translation to humans?
Giuseppe Danilo Norata · 2018 · Cardiovascular Research
Infection History Determines Susceptibility to Unrelated Diseases
Nikolas Rakebrandt, Nicole Joller · 2019 · BioEssays
Myeloid Responses to Extracellular Vesicles in Health and Disease
Priya Makhijani, Tracy L. McGaha · 2022 · Frontiers in Immunology
Monocytes presenting a pro-inflammatory profile persist in patients submitted to a long-term pharmacological treatment after acute myocardial infarction
Daniel Carneiro de Carvalho, Francisco Antônio Helfenstein Fonseca, Maria Cristina de Oliveira Izar, Ana Luíza Pereira Assunção Silveira, Izabela Tuleta, Jônatas Bussador do Amaral, Lucas Melo Neves, André Luís Lacerda Bachi, Carolina Nunes França · 2023 · Frontiers in Physiology
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment
Lisiena Hysenaj, Bérengère de Laval, Vilma Arce Gorvel, Mile Bosilkovski, Gabriela González-Espinoza, Guilhaume Debroas, Michael H. Sieweke, Sandrine Sarrazin, Jean‐Pierre Gorvel · 2023 · The Journal of Experimental Medicine
Bone Marrow Harbors a Unique Population of Dendritic Cells with the Potential to Boost Neutrophil Formation upon Exposure to Fungal Antigen
Marieke Goedhart, Edith M. Slot, María Fernanda Pascutti, Sulima Geerman, Timo Rademakers, Benjamin Nota, Stephan Huveneers, Jaap D. van Buul, Katherine C. MacNamara, Carlijn Voermans et al. · 2021 · Cells
The wild mouse bone marrow has a unique myeloid and lymphoid composition and phenotype
Andrew Muir, Alex Bennett, Hannah Smith, Larisa Logunova, Andrew Wolfenden, Jonathan Fenn, Ann Lowe, Andy Brass, John R. Grainger, Joanne Elizabeth Konkel et al. · 2023 · Discovery Immunology
Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
Bikul Das, Lekhika Pathak, Sukanya Gayan, Bidisha Pal, Partha Jyoti Saikia, Tutumoni Baishya, Nihar Ranjan Das, Rupam Das, Mallika Maral, Ranjit Mahanta et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Human Bacille Calmette-Guérin Vaccination Elicits Trained Immunity Via the Hematopoietic Progenitor Compartment
Branko Cirovic, L. Charlotte J. de Bree, Laszlo A. Groh, B. A. Blok, J. Chan, Walter J. F. M. van der Velden, Manita E. J. Bremmers, Reinout van Crevel, K. Händler, Simone Picelli et al. · 2019 · SSRN Electronic Journal
Protective immune response against Rhodococcus equi : An innate immunity‐focused review
Bibiana Petri da Silveira, Noah D. Cohen, Sara D. Lawhon, Robert O. Watson, Angela Ilha Bordin · 2024 · Equine Veterinary Journal
β-Glucan modulates trained immunity to inhibit osteoclast differentiation via NOD2/RIPK2 signaling pathway
Yanjie Li, Mingzhu Chen, Zhen-jin Yang, Junxiong Li, Liya Ma, Guangyu Bao, Yanxia Chen, Jiang-tian Hu · 2025 · International Immunopharmacology
Inflammatory memory of stem cells: implications for hematologic diseases
Dongchang Zhao, Pavan R. Reddy · 2025 · Blood
Central trained immunity in the context of bladder cancer immunotherapy
Julia Chronopoulos, María Crespo, Triantafyllos Chavakis · 2025 · Cancer Cell
Monocyte/macrophage-mediated trained immunity in disease prevention and immunotherapy
Xiao Zhang, Xinlian Wang, Mei‐Yan Xu, Jing Yuan, Ying Liu · 2026 · Bioactive Materials
Trained immunity in acute and chronic neurological diseases
Sijia Zhang, Arthur Liesz · 2026 · eLife
Trained immunity in monocytes and macrophages in atherosclerotic cardiovascular disease
Xiaoyi Zhang, Mo Wang, Yunshan Wang, Li Li, Shuai Wang, Yang Xiang · 2026 · Cardiovascular Research
Trained Innate Immunity in Animal Models of Cardiovascular Diseases
Patricia Kleimann, Lisa-Marie Irschfeld, Maria Grandoch, Ulrich Flögel, Sebastian Temme · 2024 · International Journal of Molecular Sciences
Preventive effects of prenatal administration of OM ‐85/ BV on asthma and respiratory infection risk in the offspring: A review of animal models
Signe Hahn Rahbek‐Hansen, Marianne Mikkelsen, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes, Nicklas Brustad · 2024 · Pediatric Allergy and Immunology
A comparative study on the immune response in the head and trunk kidney of yellow catfish infected with Edwardsiella ictaluri
Mengge Guo, Ruhan Sun, Zhengyan Wu, Anqi Li, Qin Wang, Zhangchun Zhao, Huimin Liu, Bingchao Wang, Ke Xiao, Ze-Chao Shi et al. · 2024 · Fish & Shellfish Immunology
Strategy against super-resistant bacteria: Curdlan-induced trained immunity combined with multi-epitope subunit vaccine
Hai Li, Lingdi Niu, Jiaqing Wang, Qingru Chang, Shuhe Zhang, Jiaqi Wang, Jiankai Zeng, Mingchun Gao, Junwei Ge · 2024 · International Journal of Biological Macromolecules
Deciphering the Complexities of Adult Human Steady State and Stress-Induced Hematopoiesis: Progress and Challenges
Suzanne M. Watt, Maria G. Roubelakis · 2025 · International Journal of Molecular Sciences
Timing matters in macrophage/CD4+ T cell interactions: an agent-based model comparing Mycobacterium tuberculosis host-pathogen interactions between latently infected and naïve individuals
Alexis Hoerter, Alexa Petrucciani, Jordan R. Bonifacio, Eusondia Arnett, Larry S. Schlesinger, Elsje Pienaar · 2025 · mSystems
Antigen-presenting innate lymphoid cells induced by BCG vaccination promote a respiratory antiviral immune response through the skin‒lung axis
Dou Yu, Xintong Gao, Fei Shao, Zhen Liu, Aoyi Liu, Min Zhao, Zhuozhou Tang, Yude Guan, Shuo Wang · 2025 · Cellular and Molecular Immunology
Food for Training—Western Diet and Inflammatory Memory
Parimal Samir, R. K. Subbarao Malireddi, Thirumala‐Devi Kanneganti · 2018 · Cell Metabolism
Metabolomics Analysis of Splenic CD19+ B Cells in Mice Chronically Infected With Echinococcus granulosus sensu lato Protoscoleces
Yuxin Guo, Daxiang Xu, Zheng Fang, Shiping Xu, Jiaxi Liu, Zixuan Xu, Jikai Zhou, Zhenzhen Bu, Zhao Yingyi, Jingmei He et al. · 2021 · Frontiers in Veterinary Science
Long noncoding RNAs: Emerging players regulating innate immune memory in the red flour beetle
Hesham M. Abd El Halim, Ali Ali · 2021 · Developmental & Comparative Immunology
Genetic dissection of innate immune memory in Drosophila melanogaster
Chang Tang, Shoichiro Kurata, Naoyuki Fuse · 2022 · Frontiers in Immunology
β-Glucan ameliorates anxiety-like behavior in mice chronically infected with the Toxoplasma gondii Wh6 strain
Daxiang Xu, Ziyi Yan, Yuying Zhou, Yan He, Shuxi Liu, Zixuan Gao, Xiyue Zhang, Xiaohui Ding, Yinghua Yu, Xiaoying Yang et al. · 2022 · Parasitology Research
Trained immunity: A link between risk factors and cardiovascular disease
Mingqi Chen, Xuya Kang, Yan Zhang, Yahan Liu · 2024 · British Journal of Pharmacology
Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology
Shirin Kalyan, Mark Bazett, Ho Pan Sham, Momir Bosiljcic, Beryl Luk, Salim Dhanji, Amanda M. Costa, Stephanie WY Wong, Mihai Gheorghe Netea, David W. Mullins et al. · 2020 · Scientific Reports
Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice
Tobias Koeniger, Luisa Bell, Anika Mifka, Michael Enders, Valentin Hautmann, Subba Rao Mekala, Philipp Kirchner, Arif Bülent Ekici, Christian Schulz, Philipp Wörsdörfer et al. · 2020 · Stem Cells
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics
Juana Serrano‐López, Shailaja Hegde, Sachin Kumar, Josefina Serrano, Jing Fang, Ashley M. Wellendorf, Paul A. Roche, Yamileth Rangel, Léolène J. Carrington, Hartmut Geiger et al. · 2021 · eLife
Postnatal inflammation in ApoE−/− mice is associated with immune training and atherosclerosis
Ellesandra C. Noye, Siroon Bekkering, Albert Prabowo Limawan, Maria U. Nguyen, Lisa K. Widiasmoko, Hui Lü, Salvatore Pepe, Michael M.H. Cheung, Trevelyan R. Menheniott, Megan J. Wallace et al. · 2021 · Clinical Science
Training myeloid precursors with fungi, bacteria and chips
Manfred Köpf, Peter J. Nielsen · 2018 · Nature Immunology
BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow
Sarah J. Sun, Raúl Aguirre‐Gamboa, L. Charlotte J. de Bree, Joaquín Sanz, Anne Dumaine, Leo A. B. Joosten, Maziar Divangahi, Mihai Gheorghe Netea, Luis Bruno Barreiro · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Microbial cancer immunotherapy reprograms hematopoiesis to enhance anti-tumor immunity
Andrew W. Daman, Anthony C. Antonelli, Gil Redelman‐Sidi, Lucinda Paddock, Jin‐Gyu Cheong, Leonardo F. Jurado, Anna Binyamin, Song Jiang, Dughan J. Ahimovic, Shireen Khayat et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
The role of the microbiota in myelopoiesis during homeostasis and inflammation
Yeji Kim, Nobuhiko Kamada · 2023 · International Immunology
Inhibition of osteosarcoma lung metastases by β-glucan and CD40 agonist is mediated by activation of macrophages and NK cells
Pradeep Shrestha, Rejeena Shrestha, Eugenie S. Kleinerman · 2025 · Journal for ImmunoTherapy of Cancer
Engineered long-acting Irisin-albumin binding domain fusion protein for enhanced anti-inflammatory efficacy in lipopolysaccharide-induced systemic inflammation
Jicun Zhu, Yujie Zhang, Xinwei Wang, Lei Peng, Xiaojun Ma, Zan Qiu, Zirui Kang, Fangyuan Zheng, Xiaoyu Zhang, Mengyuan Song et al. · 2025 · Communications Biology
Defining the marker and developmental trajectory of myeloid-derived suppressor cells in aging by single-cell transcriptomics
Yaru Su, Rongjie Wu, Haochen Ai, Zhaoming Zhong, Lin Zou, Zihan Wang, Kewu Tu, Lu Tang, Jiawen Gao, Yusheng Huang et al. · 2025 · npj Aging
Structural characterization of Taiwanofungus camphoratus polysaccharide and its ameliorative effects on myelosuppression and immunosuppression by regulating macrophage activation
Yawen Wang, Jianbin Wang, Hang Lian, Xueting Liu, Jiahao Zheng, Leyi Wang, Juan Liang, Xinyue Wei, Yange Liu · 2026 · Carbohydrate Polymers
Trained Immunity in Neutrophils and Mononuclear Phagocytes: Mechanisms and Pathophysiological Functions
Wanying Li, Jialei Wei, Liyuan Li, Wei Sun · 2026 · Cells
Early-life β-glucan exposure enhances disease resilience of broiler chickens to a natural Clostridium perfringens infection
Wanwei He, Mohammad Kamely, Jeremy Wakaruk, Emanuele Cristiny Goes, D.R. Korver, Daniel R. Barreda · 2022 · Developmental & Comparative Immunology
Impact of exercise on brain-bone marrow interactions in chronic stress: potential mechanisms preventing stress-induced hypertension
Thu Van Nguyen, Ko Yamanaka, Keisuke Tomita, Jasenka A Zubcevic, Sabine S. Gouraud, Hidefumi Waki · 2023 · Physiological Genomics
Trained Innate Immunity
Sayanti Pal, Zaina Rafiq, Rekha Kumari, Ahmad Al Aiyan, Basel K. al-Ramadi, Uday Kishore, Pretty Ponnachan · 2025 · Advances in experimental medicine and biology
Epigenetics and Medicine
Giuseppe Cocco, Philipp Amiet · 2021 · OBM Genetics
Hypoxia signalling in the regulation of innate immune training
Eades, L, Drozd, M, Cubbon, R · 2022 · White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
Modulation of haematopoiesis by protozoal and helminth parasites
Kyle T. Cunningham, Kingston H. G. Mills · 2023 · Parasite Immunology
Elucidating the cell metabolic heterogeneity during hematopoietic lineage differentiation based on Met-Flow
Haoyue Liang, Sen Zhang, Yao Ma, Haoyu Wang, Zhijie Cao, Ruxue Shi, Xiaodong Kong, Qiang Zhang, Yuan Zhou · 2023 · International Immunopharmacology
F4/80 + CD206 + M2-like macrophages contribute to bone erosion in collagen-induced arthritis by differentiating into osteoclasts
HeHe Sun, Hong-Min Wang, Chen‐Hui Gao, Li Tai, Yueyao Yang, Hongliang Dong, Xiao‐Ming Gao · 2023 · European Journal of Inflammation
Getting to the Marrow of Trained Immunity
Laszlo A. Groh, Mihai Gheorghe Netea, Niels Peter Riksen, Samuel T. Keating · 2018 · Epigenomics
Age-Specific Differences in the Severity of COVID-19 Between Children and Adults: Reality and Reasons
Amir Tajbakhsh, Khojaste Rahimi Jaberi, Seyed Mohammad Gheibi Hayat, Mehrdad Sharifi, Thomas P. Johnston, Paul C. Guest, Mohammad Jafari, Amirhossein Sahebkar · 2021 · Advances in experimental medicine and biology
Current Perspectives on Viral Disease Outbreaks - Epidemiology, Detection and Control
Claborn, David · 2020 · IntechOpen eBooks
Do bacterial vaccines/adjuvants prevent wheezing episodes in children?
Antonio Nieto, María Nieto, Laura Conejero, José Luis Subiza · 2022 · Current Opinion in Allergy and Clinical Immunology
Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury
Antonio Hernandez, Naeem K. Patil, Maya Brewer, Rachel Delgado, Lauren E. Himmel, Lauren N. Lopez, Julia K. Bohannon, Allison M. Owen, Edward R. Sherwood, Mark P. de Caestecker · 2023 · American Journal of Physiology-Renal Physiology
Memoria inmunológica innata, la pieza faltante de la respuesta inmunológica
Diego Pérez-Vázquez, Eugenio Contreras-Castillo, Paula Licona-Limón · 2018 · TIP Revista Especializada en Ciencias Químico-Biológicas
Innate Immunity and Neuroinflammation in Neuropsychiatric Conditions Including Autism Spectrum Disorders: Role of Innate Immune Memory
Harumi Jyonouchi · 2019 · IntechOpen eBooks
Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells
Jason Nideffer, Maureen Ty, Michele Donato, Rek John, Richard Kajubi, Xuhuai Ji, Holden Terry Maecker, Felistas Nankya, Kenneth Musinguzi, Kathleen D. Press et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Breast Cancer Immunity: It is TIME for the Next Chapter
Daniela F. Quail, Morag Park, Alana L. Welm, H. Atakan Ekiz · 2023 · Cold Spring Harbor Perspectives in Medicine
Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses
Audrey W. Q. Lee, Katharine A. Floyd, Shengyang Wu, Zhuoqing Fang, Tze-Kai Tan, Chunfeng Li, Harold Sai-yin Hui, David Scoville, Alistaire D. Ruggiero, Yan Liang et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Cardiopulmonary neuro-immune reflex: From afferent stress signaling to peripheral myeloid memory
Junichi Sugita, Ziyu Chen, Naoto Setoguchi, Kohsaku Goto, Atsushi Kobayashi, Kunihiko Kani, Yiyi Yang, Jiaxin Ku, Kensuke Ueno, Ryoko Uchida et al. · 2025 · Journal of Cardiology
Functions of Macrophages in Periodontal Disease Progression and Gingival Tissue Homeostasis
Tsuguno Yamaguchi · 2025 · Advances in experimental medicine and biology
Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors
Marco De Zuani, Petra Lázničková, Marcela Hortová Kohoutková, Veronika Bosáková, Ivana Andrejčinová, Natália Vadovičová, Veronika Tomášková, Alexandra Mýtniková, Julie Štíchová, Tomáš Tomáš et al. · 2026 · Journal of Inflammation
Harnessing myeloid cell plasticity for cancer therapy
Emilio Sanseviero, Simon T. Barry, Dmitry I. Gabrilovich · 2026 · Nature Cancer
Metabolic support of trained immune responses in myeloid cells
Aitor Jarit-Cabanillas, Gillian Dunphy, Federico Virga, Jan Van den Bossche, David Sancho · 2026 · eLife
Discovery of Potent and Selective CDK4/6 Inhibitors for the Treatment of Chemotherapy-Induced Myelosuppression
Wei Shi, Rong Wang, Jianqiang Qian, Lu Wang, You Li, Yahui Mi, Zhaotong Jia, Mingshi Pan, Xiao‐Qi Zhang, Wen‐Cai Ye et al. · 2025 · Journal of Medicinal Chemistry
Immunomodulatory Effect of the Bacillus Calmette–Guérin (BCG) Vaccine on the In Vitro Interferon Response Induced by Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigens
Magdalena Jurczak, Joanna Kaczmarek, Magdalena Kowalewska-Pietrzak, Magdalena Druszczyńska · 2025 · Archivum Immunologiae et Therapiae Experimentalis
Hematopoietic stem and progenitor cells fine-tuning the “sweet” of trained immunity
Jiawei Li, Hui Wang, Sheng Xia · 2025 · Journal of Leukocyte Biology
Divergent metabolic rewiring shapes altered innate immunity
Mohua Liu, Xiao Wang, Xiaoya Qu, Yao Wang, Xihui Shen, Lei Xu · 2025 · Cellular Immunology
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
Samuel Tanner Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika González-Lopez, Jose‐Ezequiel Martín, Elena Molina, Maitane Mugica et al. · 2025 · Immunology
Trained immunity in skin infections: Macrophages and beyond
Vitka Gres, Merve Göcer, Julia Kolter, Philipp Henneke · 2025 · eLife
Periodontitis Promotes OSCC and Prostate Cancer Progression and Immunosuppression by Skewing Myeloid Differentiation of HSPCs
F. Nie, Shuyun Wang, Hong Tian, Jing Zhang, Q. Yin, J. Ju, P. Gong, Jiayi Liu, Pishan Yang, Chunshan Yang · 2025 · Journal of Dental Research
Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation
Tiago Medeiros-Furquim, Sinan Ayoub, Laura J. Johnson, Andrea Aprico, Eze C. Nwoke, Michele D. Binder, Trevor John Kilpatrick · 2022 · Frontiers in Immunology
Novel approaches to preventing phagosomal infections: timing is key
Nathan C. Peters, Nargis Khan, Christopher H. Mody · 2022 · Trends in Immunology
Multidimensional futuristic approaches to address the pandemics beyond COVID-19
Shifa Bushra Kotwal, Nidhi Orekondey, Gargi Prasad Saradadevi, Neha Priyadarshini, Navinchandra Venkatarama Puppala, Mahak Bhushan, Snehasri Motamarry, Rahul Kumar, Gireesha Mohannath, Ruchi Jain Dey · 2023 · Heliyon
Trained Immunity at a Glance; A Review on the Innate Immune Memory and its Potential Role in Infections, Diseases and New Therapeutic Strategies
Silvia Incalcaterra, Jorge Andres Dominguez · 2020 · Advanced Journal of Graduate Research
BCG vaccination as protection from COVID-19: epidemiological and molecular biological aspects
Ya. Sh. Shvаrts, N. V. Stavitskaya, Dmitry Anatolievich Kudlay · 2020 · Tuberculosis and lung diseases