Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
Khajuria, Rajiv K., Munschauer, Mathias, Ulirsch, Jacob C., Fiorini, Claudia, Ludwig, Leif S., McFarland, Sean K., Abdulhay, Nour J., Specht, Harrison +19 more·2018·Cell
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- Altered translation efficiency of specific mRNAs in a zebrafish model of Diamond-Blackfan anemia syndromeTamayo Uechi, Mariko Nagatomo, Yukari Nakajima, Yutaka Suzuki, Naoya Kenmochi · 2026 · Biochemical and Biophysical Research Communications
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- Manipulation of protein translation and stem cell self-renewal by CRISPR activation of rRNA transcriptionMaximilian F. Wiesbeck, Emilie L. Alard, Florencia Merino, Niti Chowdhury, Luisa Egert, Anna Danese, Simon Imhof, Matilde Iraci Borgia, Akshaya Rajan, Nadine Fernandez-Novel Marx et al. · 2026 · Science
- METTL5-mediated rRNA modification controls prostate cancer progression through the IRF7/DNA2 axis and mitophagy regulationRuifeng Yang, Qintao Ge, Fengyao Wu, 龙满美, Bingyu Li, zhe Hong, Wenhao Xu, Miaomiao Guo, Tao Feng, Xi Tian et al. · 2026 · Oncogene
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- Ribosome biogenesis and selective translational control as oncogenic vulnerabilities in hematologic malignanciesJuan Luiz Coelho‐Silva, João Agostinho Machado‐Neto · 2026 · Molecular Cancer
- Ribosomal RNA transcription in normal and leukemic hematopoiesisJill A. Henrich, Eleanor I. Sams, Vikram R. Paralkar · 2026 · Current topics in developmental biology/Current Topics in Developmental Biology
- Decoding the erythroid niche: From single-cell programs to spatially resolved architecture in mouse and human hematopoiesisPan Wang, Kehan Ren, Peng Ji · 2026 · Current topics in developmental biology/Current Topics in Developmental Biology
- Comparative toxicoproteomics reveals distinct proteostasis and ribosomal stress signatures of CMIT and PHMGYe-Eun Jeong, Min Jeong Jeon, Hyung‐Sun Youn, Jiyou Han, Mi Young Lee · 2026 · Toxicology in Vitro
- RpS19a depletion alters the hematopoietic translatome to drive tissue overgrowthNaomi C. Mitchell, Arjun Chahal, Tanya Javaid, Katrina Woodward, Ralf B. Schittenhelm, Cheng Huang, Julie Lorent, Jiwon Lee, Melanie Rug, Amee J. George et al. · 2026 · iScience
- From chromatin to proteostasis: multilevel gene regulation in Mendelian diseasesHimanshu Goel, Gunjan Garg · 2026 · Frontiers in Epigenetics and Epigenomics
- Declining ribosome function limits oocyte longevityKayla Lee Judson, Katie Jordanna Danielson, Shuang Tang, Sahil Chandhok, Elizabeth Hui, Fiona Wong, Thibault Mayor, Karen Schindler, Ethan J. Greenblatt · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- A small modification makes a big difference: rRNA modifications in hematopoiesis and leukemiaNeta Ifergan, Sivan Ben Dror, Daphna Nachmani · 2026 · Seminars in Hematology
- Cartilage-hair hypoplasia: A ribosomopathyNic Robertson, Andrew R Gennery · 2026 · Seminars in Hematology
- Ribosome Structure, Function and Dysfunction at the Molecular LevelRuta Chitale, Alan M. Johnson · 2026 · Seminars in Hematology
- Loss of Tars induces proteostasis stress and drives HSPC exhaustion through mTORC1 activationNing-Zhe Li, Meng-ke He, Qiang Wang, Na Liu, Zixuan Wang, Ming-kang Qi, Yi Chen, Rufang Xiang, Yu-ting Dai, Fan Zhang · 2026 · Acta Pharmacologica Sinica
- A zebrafish ribosomopathy links Ddx49-dependent ribosome biogenesis to differential failure of population expansion among pigment cell lineagesYipeng Liang, Kinga Malezyna, Abigail J Dennis, Abhishek Kumar, Braedan M. McCluskey, Diane S. Sepich, Lilianna Solnica‐Krezel, Arunkumar Dhayalan, Ahmad Jomaa, Larissa B. Patterson et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)