Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

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Items 501–600 of 1,682

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  2. Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes
    M. Wertz, S. S. Pineda, Hyeseung Lee, R. Kulicke, Manolis Kellis, M. Heiman · 2020 · Molecular Neurodegeneration
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    Kenneth Blum, Abdalla Bowirrat, Keerthy R. Sunder, Panayotis K. Thanos, Colin Hanna, Mark S. Gold, Catherine A. Dennen, Igor Elman, Kevin T. Murphy, Milan T. Makale · 2024 · Brain Sciences
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  5. Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq
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  6. scClustViz – Single-cell RNAseq cluster assessment and visualization
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  7. The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis
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    Michael N. Economo, Johan Winnubst, Erhan Bas, Tiago Ferreira, Jayaram Chandrashekar · 2019 · The Journal of Comparative Neurology
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    Kathleen Carmichael, Breanna T Sullivan, Elena Lopez, Lixin Sun, Huaibin Cai · 2021 · Ageing and Neurodegenerative Diseases
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    Jan Spaas, Wouter M. A. Franssen, Charly Keytsman, Laura Blancquaert, Tim Vanmierlo, Jeroen F. J. Bogie, Bieke Broux, Niels Hellings, Jack van Horssen, Dheeraj Kumar Posa et al. · 2021 · Journal of Neuroinflammation
  11. Cellular Specificity and Inter-cellular Coordination in the Brain Bioenergetic System: Implications for Aging and Neurodegeneration
    Guoyuan Qi, Yashi Mi, Fei Yin · 2020 · Frontiers in Physiology
  12. Activity labeling in vivo using CaMPARI2 reveals intrinsic and synaptic differences between neurons with high and low firing rate set points
    Nicholas F. Trojanowski, Juliet Bottorff, Gina G. Turrigiano · 2020 · Neuron
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    Xiaojie Qiu, Daniel Y. Zhu, Jiajun Yao, Zehua Jing, Lulu Zuo, Mingyue Wang, Kyung Hoi Min, Hailin Pan, Shuai Wang, Sha Liao et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Microglial heterogeneity in chronic pain
    George Sideris-Lampretsas, Marzia Malcangio · 2021 · Brain Behavior and Immunity
  15. Systems spatiotemporal dynamics of traumatic brain injury at single-cell resolution reveals humanin as a therapeutic target
    Douglas V. Arneson, Guanglin Zhang, In Sook Ahn, Zhe Ying, Graciel Diamante, Ingrid Cely, Victoria Palafox-Sánchez, Fernando Gómez‐Pinilla, Xia Yang · 2022 · Cellular and Molecular Life Sciences
  16. Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy
    Stephanie N. Fox, Laura J. McMeekin, Cody H. Savage, Kathlene L. Joyce, Stephanie M. Boas, Micah S. Simmons, Charlene B. Farmer, J. Ryan, Larisa Pereboeva, Katelyn Becker et al. · 2022 · npj Parkinson s Disease
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  19. Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development
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  20. An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity
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  22. Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons
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  23. Modeling Down syndrome in animals from the early stage to the 4.0 models and next
    Maria del Mar Muñiz Moreno, Véronique Brault, Marie‐Christine Birling, Guillaume Pavlovic, Yann Hérault · 2020 · Progress in brain research
  24. A multimodal cell census and atlas of the mammalian primary motor cortex
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  25. Looking at neurodevelopment through a big data lens
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  26. Biallelic variants in HPDL, encoding 4-hydroxyphenylpyruvate dioxygenase-like protein, lead to an infantile neurodegenerative condition
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  28. Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes
    Sofía Puvogel, Astrid M. Alsema, Laura Kracht, Maree J. Webster, Cynthia Shannon Weickert, Iris E. Sommer, Bart J. L. Eggen · 2022 · Molecular Psychiatry
  29. Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats
    Zafar Iqbal, Zhuogui Lei, Aruna Surendran Ramkrishnan, Shu Liu, Mahadi Hasan, Mastura Akter, Yuk Yan Lam, Ying Li · 2023 · Communications Biology
  30. The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
    Barney Viengkhou, Emina Hayashida, Sarah L. McGlasson, Katie Emelianova, Deborah Forbes, Stewart J. Wiseman, Joanna Marguerite Wardlaw, Rovin Verdillo, Sarosh R. Irani, Darragh Duffy et al. · 2024 · Immunity
  31. Astrocyte development—More questions than answers
    Kathryn M. Markey, Jillian C. Saunders, Jana Smuts, Catherine R. von Reyn, A. Denise R. Garcia · 2023 · Frontiers in Cell and Developmental Biology
  32. Diverse GABAergic neurons organize into subtype‐specific sublaminae in the ventral lateral geniculate nucleus
    Ubadah Sabbagh, Gubbi Govindaiah, Rachana Deven Somaiya, Ryan V. Ha, Jessica Wei, William Guido, Michael A. Fox · 2020 · Journal of Neurochemistry
  33. NECAB1 and NECAB2 are Prevalent Calcium-Binding Proteins of CB1/CCK-Positive GABAergic Interneurons
    Vivien Miczán, Krisztina Kelemen, Judit R Glavinics, Zsófia I. László, Benjámin Barti, Kata Kenesei, Máté Kisfali, István Katona · 2020 · Cerebral Cortex
  34. A phylogenetically-conserved axis of thalamocortical connectivity in the human brain
    Stuart Oldham, Gareth Ball · 2023 · Nature Communications
  35. Structures of neurexophilin–neurexin complexes reveal a regulatory mechanism of alternative splicing
    Steven C. Wilson, K. Ian White, Qiangjun Zhou, Richard A. Pfuetzner, Ucheor Brandon Choi, Thomas Christian Südhof, Axel T. Brünger · 2019 · The EMBO Journal
  36. Control of neural development and function by glial neuroligins
    Kristina Sakers, Çağla Eroğlu · 2019 · Current Opinion in Neurobiology
  37. Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity
    Jinxu Liu, Gajanan P. Shelkar, Pauravi J. Gandhi, Dinesh Yugraj Gawande, Andrew H. Hoover, Rosa María Villalba, Ratnamala Pavuluri, Yoland Smith, Shashank Manohar Dravid · 2020 · Neurobiology of Disease
  38. Modal-nexus auto-encoder for multi-modality cellular data integration and imputation
    Zhenchao Tang, Guanxing Chen, Shouzhi Chen, Jianhua Yao, Linlin You, Calvin Yu‐Chian Chen · 2024 · Nature Communications
  39. Dynamic modulation of the blood–brain barrier in the healthy brain
    Alon Friedman, Ofer Prager, Yonatan Serlin, Daniela Kaufer · 2025 · Nature reviews. Neuroscience
  40. Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain
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  41. Query to reference single-cell integration with transfer learning
    Mohammad Lotfollahi, Mohsen Naghipourfar, Malte D. Luecken, Matin Khajavi, Maren Büttner, Žiga Avsec, Alexander V. Misharin, Fabian Joachim Theis · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  42. A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes
    Philip Dusart, Björn M. Hallström, Thomas Renné, Jacob Odeberg, Mathias Uhlén, Lynn M. Butler · 2019 · Cell Reports
  43. Graded Coexpression of Ion Channel, Neurofilament, and Synaptic Genes in Fast-Spiking Vestibular Nucleus Neurons
    Takashi Kodama, Aryn H. Gittis, Minyoung Shin, Keith J. Kelleher, Kristine E. Kolkman, Lauren E. McElvain, Minh Lam, S du Lac · 2019 · Journal of Neuroscience
  44. Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum
    Roger Shen Zhang, Kifayathullah Liakath‐Ali, Thomas Christian Südhof · 2020 · eLife
  45. A versatile and scalable single-cell data integration algorithm based on domain-adversarial and variational approximation
    Jialu Hu, Yuanke Zhong, Xuequn Shang · 2021 · Briefings in Bioinformatics
  46. A primate nigrostriatal atlas of neuronal vulnerability and resilience in a model of Parkinson’s disease
    Lei Tang, Nana Xu, Mengyao Huang, Wei Yi, Xuan Sang, Mingting Shao, Ye Li, Zhao-Zhe Hao, Ruifeng Liu, Yuhui Shen et al. · 2023 · Nature Communications
  47. Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells
    Lorenzo Lazzerini Ospri, Jesse J. Zhan, Michael B Thomsen, H. M. Wang, Ruchi Komal, Qijun Tang, Fany Messanvi, Johann du Hoffmann, Kevin Cravedi, Yogita Chudasama et al. · 2024 · Science Advances
  48. Brain endothelial specific gene therapy improves experimental Sandhoff disease
    Godwin Dogbevia, Hanna Graßhoff, Alaa Othman, Anke Penno, Markus Schwaninger · 2019 · Journal of Cerebral Blood Flow & Metabolism
  49. Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation
    Govek, Kiya W., Chen, Sixing, Sgourdou, Paraskevi, Yao, Yao, Woodhouse, Steven, Chen, Tingfang, Fuccillo, Marc V., Epstein, Douglas J., Camara, Pablo G. · 2022 · Cell Reports
  50. Synaptic activity–dependent changes in the hippocampal palmitoylome
    Glory G Nasseri, Nusrat Matin, Kira N. Tosefsky, Greg Stacey, Stéphane Flibotte, Rocio Hollman, Angela R. Wild, Leonard J. Foster, Shernaz Xerxes Bamji · 2022 · Science Signaling
  51. A Systematic Evaluation of Interneuron Morphology Representations for Cell Type Discrimination
    Sophie Laturnus, Dmitry Kobak, Philipp Berens · 2020 · Neuroinformatics
  52. Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology
    Chaitanya Srinivasan, BaDoi N. Phan, Alyssa J. Lawler, Easwaran Ramamurthy, Michael Kleyman, Ashley R. Brown, Irene M. Kaplow, Morgan E. Wirthlin, Andreas R. Pfenning · 2021 · Journal of Neuroscience
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    Mark S. Cembrowski · 2019 · Journal of Neuroscience Methods
  54. Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data
    Parashar Dhapola, Johan Rodhe, Rasmus Olofzon, Thomas Bonald, Eva Erlandsson, Shamit Soneji, Göran Karlsson · 2022 · Nature Communications
  55. Convergence of spectrums: neuronal gene network states in autism spectrum disorder
    Josefa M. Sullivan, Silvia De Rubeis, Anne Schaefer · 2019 · Current Opinion in Neurobiology
  56. Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons
    Donna Cosgrove, Laura Whitton, Laura Fahey, Pilib Ó Broin, Gary J Donohoe, Derek W. Morris · 2020 · Human Molecular Genetics
  57. D1R- and D2R-Medium-Sized Spiny Neurons Diversity: Insights Into Striatal Vulnerability to Huntington’s Disease Mutation
    Guendalina Bergonzoni, Jessica Döring, Marta Biagioli · 2021 · Frontiers in Cellular Neuroscience
  58. Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties
    Tomás Osorno, Stephanie Rudolph, Tri Nguyen, Velina Kozareva, Naeem M. Nadaf, Aliya Norton, Evan Z. Macosko, Wei-Chung Allen Lee, Wade G. Regehr · 2022 · Nature Neuroscience
  59. Deep learning does not outperform classical machine learning for cell-type annotation
    Niklas Köhler, Maren Büttner, Niry Andriamanga, Fabian Joachim Theis · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  60. Perivascular stromal cells: Directors of tissue immune niches
    Julia Sbierski‐Kind, Nicholas M. Mroz, Ari B. Molofsky · 2021 · Immunological Reviews
  61. Current insights and assumptions on α-synuclein in Lewy body disease
    Rehana K. Leak, Rachel N. Clark, Muslim Abbas, Fei Xu, Jeffrey L. Brodsky, Jun Chen, Xiaoming Hu, Kelvin C. Luk · 2024 · Acta Neuropathologica
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  63. Role of MEIS1 in restless legs syndrome: From GWAS to functional studies in mice
    Aaro V. Salminen, Daniel D. Lam, Juliane Winkelmann · 2019 · Advances in pharmacology
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  66. Atp13a5 Marker Reveals Pericyte Specification in the Mouse Central Nervous System
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  67. LRRK2 at Striatal Synapses: Cell-Type Specificity and Mechanistic Insights
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  69. Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice
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  96. Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex
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  97. AQP4, Astrogenesis, and Hydrocephalus: A New Neurological Perspective
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  98. Calbindin and Girk2/Aldh1a1 define resilient vs vulnerable dopaminergic neurons in a primate Parkinson’s disease model
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  100. Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder
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