High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy
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These changes partially overlapped with those reported in a model of MCA-induced sarcoma treated with optimal anti-PD-1.
“These changes partially overlapped with those reported in a model of MCA-induced sarcoma treated with optimal anti-PD-1 (Gubin et al., 2018).”
From TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy (2020) · cites this paper as Gubin et al., 2018
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Diversity, Mechanisms, and Significance of Macrophage Plasticity
Locati, M., Curtale, G., & Mantovani, A. (2020) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012718 · Cited by 2,199 · see citing works
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy
Molgora, M., Esaulova, E., Vermi, W., Hou, J., Chen, Y., Luo, J., Brioschi, S., Bugatti, M., Omodei, A. S., Ricci, B., et al. (2020) · Cell · doi:10.1016/j.cell.2020.07.013 · Cited by 656 · see citing works
“Enhancement of ICT was associated with augmented T cell infiltration and activation, at least in the MCA model.”
InfluentialSelf-citationSamstein, R. M., Krishna, C., Ma, X., Pei, X., Lee, K.-W., Makarov, V., Kuo, F., Chung, J., Srivastava, R. M., Purohit, T. A., et al. (2020) · Nature Cancer · doi:10.1038/s43018-020-00139-8 · Cited by 219 · see citing works
- Authors
- Gubin, M. M., Esaulova, E., Ward, J. P., Malkova, O. N., Runci, D., Wong, P., Noguchi, T., Arthur, C. D., Meng, W., Alspach, E., Medrano, R. F. V., Fronick, C., Fehlings, M., Newell, E. W., Fulton, R. S., Sheehan, K. C. F., Oh, S. T., Schreiber, R. D., & Artyomov, M. N.
- Corresponding author
- Schreiber, Robert D.
- Artyomov, Maxim N.
- ORCID
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2018-11
- Volume
- 175
- Issue
- 5
- Pages
- 1443
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W3026809871
- Cited by
- 98
- References
- 0
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 11 · 2023: 16 · 2022: 15 · 2021: 16 · 2020: 14 · 2019: 8 · 2018: 2
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 379 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell (publishedVersion)
- Funders
- National Cancer Institute (R01CA190700, P30CA091842)
- Topics
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Keywords
- immune checkpoint inhibitors, tumor microenvironment, myeloid cells, lymphoid cells, intratumoral macrophages, macrophage polarization, CX3CR1, CD206, inducible nitric oxide synthase, tumor-infiltrating lymphocytes, antitumor immunity
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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