The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.
Mitochondrial Diseases: Hope for the Future
Open accessAbstract
Mitochondrial diseases are clinically heterogeneous disorders caused by a wide spectrum of mutations in genes encoded by either the nuclear or the mitochondrial genome. Treatments for mitochondrial diseases are currently focused on symptomatic management rather than improving the biochemical defect caused by a particular mutation. This review focuses on the latest advances in the development of treatments for mitochondrial disease, both small molecules and gene therapies, as well as methods to prevent transmission of mitochondrial disease through the germline.
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1 retracted
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Cited by
Borst, P. (2020) · IUBMB Life · doi:10.1002/iub.2367 · Cited by 252
Nakamura, T., Sato, Y., Yamada, Y., Abd Elwakil, M. M., Kimura, S., Younis, M. A., & Harashima, H. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114417 · Cited by 121
Astrocytic Changes in Mitochondrial Oxidative Phosphorylation Protein Levels in Parkinson's Disease
Chen, C., Mossman, E., Malko, P., McDonald, D., Blain, A. P., Bone, L., Erskine, D., Filby, A., Vincent, A. E., Hudson, G., et al. (2022) · Movement Disorders · doi:10.1002/mds.28849 · Cited by 36
Mitochondrial phosphoproteomes are functionally specialized across tissues
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Modelling Mitochondrial Disease in Human Pluripotent Stem Cells: What Have We Learned?
McKnight, C. L., Low, Y. C., Elliott, D. A., Thorburn, D. R., & Frazier, A. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147730 · Cited by 27
Metadata
- Authors
- Russell, O. M., Gorman, G. S., Lightowlers, R. N., & Turnbull, D. M.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 181
- Issue
- 1
- Pages
- 168-188
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W3013061819
- Cited by
- 459
- References
- 126
- FWCI
- 16.32
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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