Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

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Association and pharmacological synergism of the triple drug therapy baricitinib/remdesivir/rhACE2 for the management of COVID-19 infection

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Toxicological impact of SARS-CoV-2 on the health of the neotropical fish, Poecilia reticulata

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Janus kinase-inhibition modulates hepatitis E virus infection

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation

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Nonhuman primate models for SARS-CoV-2 research: Infrastructure needs for pandemic preparedness

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A Review of Treatment and Prevention of Coronavirus Disease 2019 among Solid Organ Transplant Recipients

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COVID-19 prevention and multiple sclerosis management: The SAFE pathway for the post-peak

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Infection‐induced inflammation from specific inborn errors of immunity to COVID‐19

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Therapeutic and anti-inflammatory effects of baricitinib on mortality, ICU transfer, clinical improvement, and CRS-related laboratory parameters of hospitalized patients with moderate to severe COVID-19 pneumonia: a systematic review and meta-analysis

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Targeting SARS-CoV-2 Main Protease (MPro) with Kinase Inhibitors: A Promising Approach for Discovering Antiviral and Anti-inflammatory Molecules against SARS-CoV-2

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mRNA-1273 vaccination protects against SARS-CoV-2–elicited lung inflammation in nonhuman primates

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Harnessing the power of IFN for therapeutic approaches to COVID-19

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Animal models for studying coronavirus infections and developing antiviral agents and vaccines

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Integrated bioinformatics analysis identifies shared immune changes between ischemic stroke and COVID 19

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Single‐cell transcriptome atlas reveals protective characteristics of COVID‐19 mRNA vaccine

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The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19

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Airway administration of bisphosphate and dexamethasone inhibits SARS-CoV-2 variant infection by targeting alveolar macrophages

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Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

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Novel insights into the ROCK-JAK-STAT signaling pathway in upper respiratory tract infections and neurodegenerative diseases

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The CXCL10‐CXCR3 Axis Induces Tumor‐Associated Neutrophils to Interfere with CTLs‐Mediated Antitumor Activity in EBV‐Associated Epithelial Cancers

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Scientific evidence in the COVID-19 treatment: A comprehensive review

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Immune response and potential therapeutic strategies for the SARS-CoV-2 associated with the COVID-19 pandemic

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A Rationale and Approach to the Development of Specific Treatments for HIV Associated Neurocognitive Impairment

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High resolution mass spectrometry‐driven metabolite profiling of baricitinib to report its unknown metabolites and step‐by‐step reaction mechanism of metabolism

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Monitoring and immunogenicity of SARS-CoV-2 vaccination of laboratory rhesus monkeys (Macaca mulatta)

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Perspectives of association Baricitinib/Remdesivir for adults with Covid-19 infection

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Siglec-1 on dendritic cells mediates SARS-CoV-2 trans -infection of target cells while on macrophages triggers proinflammatory responsesPreprint

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Baricitinib inhibits the activation of innate immune cells and exerts therapeutic effects on acute peritonitis and systemic inflammatory response syndrome

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Proteomic and Metabolomic Characterization of SARS-CoV-2-Infected Cynomolgus Macaque at Early Stage

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Protecting the endothelial glycocalyx in COVID-19

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Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

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TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaquesPreprint

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Beyond suppression: the paradox of JAK inhibitors as amplifiers of cancer immunotherapy

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A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-2

Paules, C. I., Wang, J., Tomashek, K. M., Bonnett, T., Singh, K., Marconi, V. C., Davey, R. T., Lye, D. C., Dodd, L. E., Yang, O. O., et al. (2024) · Annals of Internal Medicine · doi:10.7326/m23-2593 · Cited by 6

The glycosaminoglycan-binding chemokine fragment CXCL9(74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection

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Immunobiology of COVID-19: Mechanistic and therapeutic insights from animal models

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Exploring the mechanism of Radix Bupleuri in the treatment of depression combined with SARS-CoV-2 infection through bioinformatics, network pharmacology, molecular docking, and molecular dynamic simulation

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Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

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Increased Inflammation and Treatment of Depression: From Resistance to Reuse, Repurposing, and Redesign

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SARS‐CoV‐2 Omicron (B.1.1.529) infection in rhesus macaques, hamsters, and BALB/c mice with severe lung histopathological damage

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Mapping the Lipid Signatures in COVID-19 Infection: Diagnostic and Therapeutic Solutions

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Favorable responses to upadacitinib, a JAK1 inhibitor, in long COVID patients with predominant neuropsychiatric symptoms: case reports in 2 autistic patients and one typically developing patient

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Thrombotic storm in coronavirus disease 2019: from underlying mechanisms to its management

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Learning from COVID-19: How drug hunters can prepare for the next pandemic

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Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome

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Identification of a potential miRNA–mRNA regulatory network for ischemic stroke by using bioinformatics methods: a retrospective study based on the Gene Expression Omnibus database

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A Meta-Analysis of Rhesus Macaques (Macaca mulatta), Cynomolgus Macaques (Macaca fascicularis), African green monkeys (Chlorocebus aethiops), and Ferrets (Mustela putorius furo) as Large Animal Models for COVID-19

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Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected MicePreprint

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Rise of Macaque Models for Immunity and Infection Research

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Emerging and underrecognized viral triggers of autoimmune inflammatory rheumatic disease flares

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Efficacy and Safety of Novel Oral Antivirals in Hospitalized COVID-19 Patients: A Network Meta-Analysis of Randomized Clinical Trials

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Immunomodulatory Agents for Coronavirus Disease-2019 Pneumonia

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A Critical Assessment of COVID-19 Genomic Vaccines

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A Review of Potential Therapeutic Strategies for COVID-19

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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammationPreprint

van Rompay, K. V., Olstad, K., Sammak, R., Dutra, J. C., Watanabe, J. K., Usachenko, J., Immareddy, R., Roh, J. W., Verma, A., Lakshmanappa, Y. S., et al. (2021) · bioRxiv · doi:10.1101/2021.09.01.458520 · Cited by 3

The mutual lipid-mediated effect of the transmembrane domain of SARS-CoV-2 E-protein and glycyrrhizin nicotinate derivatives on the localization in the lipid bilayer

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques

Bosinger, S. E., Edwards, C. T., Karunakaran, K. A., Garcia, E., Beutler, N., Gagné, M., Golden, N., Aoued, H., Pellegrini, K., Burnett, M. R., et al. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1012456 · Cited by 3

Host‐modifying drugs against COVID ‐19: some successes, but not yet the breakthrough

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Care of the Seriously Ill Patient with SARS-CoV-2

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Identification of RdRp-NiRAN/JAK1 Dual-Target Drugs for COVID-19 Treatment

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Broad Auto-Reactive IgM Responses Are Common In Critically Ill COVID-19 Patients.Preprint

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Single-cell immune profiling reveals the impact of antiretroviral therapy on HIV-1-induced immune dysfunction, T cell clonal expansion, and HIV-1 persistence in vivoPreprint

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Immunogenicity of SARS-CoV-2 trimetric spike protein associated to Poly(I:C) plus AlumPreprint

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Clinical Efficacy and Adverse Events of Baricitinib Treatment for Coronavirus Disease-2019 (COVID-19): A Systematic Review and Meta-AnalysisPreprint

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