Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Winkler, Emma S., Gilchuk, Pavlo, Yu, Jinsheng, Bailey, Adam L., Chen, Rita E., Chong, Zhenlu, Zost, Seth J., Jang, Hyesun +12 more·2021·Cell

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Items 301–370 of 370

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  9. Illuminating the Fc dependence of SARS-CoV-2 neutralization
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  10. Unveiling a New Perspective on Distinguishing Omicron Breakthrough Cases and Postimmune COVID-19-Naive Individuals: Insights from Antibody Profiles
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  12. Intranasal vaccination of Syrian Hamsters with ChAd-SARS-CoV-2-S disrupts airborne transmission cycles of SARS-CoV-2
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  13. BNT162b2 COVID-19 vaccination elicits the expansion of CD16+CD8+ T cells endowed with natural killer cell features
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  14. Interaction of the endogenous antibody response with activating FcγRs enhance control of Mayaro virus through monocytes
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  15. More antibodies are not always better: Fc effector functions play a critical role in SARS-CoV-2 infection and protection
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  16. Fc-Modified Antibody in Hospitalized Severe COVID-19 Patients
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  18. Reduced Fc-mediated antibody responses after COVID-19 mRNA vaccination in a cohort of people living with HIV-1
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  20. Evaluation of the efficacy of four anti-SARS-CoV-2 antibodies after vaccination using kits from two manufacturers: A prospective, longitudinal, cohort study at 11 serial time points within 160 days
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  22. Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters
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  34. Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance
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  35. Humoral immune responses against seasonal coronaviruses predict efficiency of SARS-CoV-2 spike targeting, FcγR activation, and corresponding COVID-19 disease severity
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  36. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in rhesus macaques
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