Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

Eugenin, E.A., Gaskill, P.J., Berman, J.W.·2009·Cellular Immunology
DOI 10.1016/j.cellimm.2008.08.005

Cited by (264)

Items 201–264 of 264

  1. HIV-induced RSAD2/Viperin supports sustained infection of monocyte-derived macrophages
    U. Zankharia, Y. Yi, Fang Lu, O. Vladimirova, Bhanu Chandra Karisetty, Jayamanna Wikramasinghe, Andrew V. Kossenkov, R. G. Collman, P. Lieberman · 2024 · Journal of Virology
  2. Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders
    Valentina Buffa, José Roberto Alvarez Vargas, Anne H. M. Galy, Simone Spinozzi, Céline J. Rocca · 2023 · Frontiers in Genome Editing
  3. Cell-to-cell transmission of lymphocytic choriomeningitis virus MX strain during persistent infection and its influence on cell migration.
    M. Labudova, Fedor Čiampor, S. Pastoreková, Jaromir Pastorek · 2018 · Acta virologica
  4. The placental battlefield: viral strategies and immune countermeasures
    Ruby Dhar, Sunil Singh, O. S. Sahoo, Nilesh Chandra, Anamta Gul, I. Mukherjee, Shreyashi Karmakar, Mohammed Amanullah, S. Karmakar · 2025 · Frontiers in Immunology
  5. Nonlytic Egress and Transmission in the Virus World
    N. Altan-Bonnet, Mamata Panigrahi · 2025 · Annual Review of Biochemistry
  6. Heparan sulfate proteoglycans: Mediators of cellular and molecular Alzheimer's disease pathogenic factors via tunnelling nanotubes?
    Duy LB Nguyen, Rachel K. Okolicsanyi, Larisa Margaret Haupt · 2024 · Molecular and Cellular Neuroscience
  7. Tunneling nanotubes and tumor microtubes—Emerging data on their roles in intercellular communication and pathophysiology: Summary of an International FASEB Catalyst Conference October 2023
    E. Lou, C. Vérollet, F. Winkler, Chiara Zurzolo, Silvana Valdebenito-Silva, E. Eugenin · 2024 · The FASEB Journal
  8. Human immunodeficiency virus transmission—Mechanisms underlying the cell‐to‐cell spread of human immunodeficiency virus
    Marta S. Calado, David Pires, Carolina M. Conceição, Quirina Santos‐Costa, Elsa Anes, José Miguel Azevedo‐Pereira · 2023 · Reviews in Medical Virology
  9. The role of tunneling nanotubes during early stages of HIV infection and reactivation: implications in HIV cure
    Silvana Valdebenito, Akira Ono, Li-Bin Rong, E. Eugenin · 2023 · NeuroImmune Pharmacology and Therapeutics
  10. TNTdetect.AI: A Deep Learning Model for Automated Detection and Counting of Tunneling Nanotubes in Microscopy Images
    Yasin Ceran, Hamza Ergüder, Katherine J. Ladner, Sophie Korenfeld, Karina Deniz, Sanyukta Padmanabhan, Phillip Wong, Murat Baday, Thomas Pengo, Emil Lou et al. · 2022 · Cancers
  11. Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice
    S. Leist, H. Kollmus, Bastian Hatesuer, R. L. O. Lambertz, K. Schughart · 2016 · Virology Journal
  12. Artificial nanotube connections and transport of molecular cargo between mammalian cells
    Haijiang Zhang, Shijun Xu, Gavin D. M. Jeffries, Owe Orwar, Aldo Jesorka · 2013 · Nano Communication Networks
  13. Evidence of ongoing replication in a human immunodeficiency virus type 1 persistently infected cell line.
    I. Olivares, Carmen Sánchez-Jiménez, C. R. Vieira, V. Toledano, M. Gutiérrez-Rivas, C. López-Galíndez · 2013 · Journal of General Virology
  14. Modeling bidirectional transport of quantum dot nanoparticles in membrane nanotubes
    Andrey V. Kuznetsov · 2011 · Mathematical Biosciences
  15. HIV-1 Trans Infection via TNTs Is Impeded by Targeting C5aR
    Giulia Bertacchi, Wilfried Posch, Doris Wilflingseder · 2022 · Biomolecules
  16. M CELLS ARE THE IMPORTANT POST IN THE INITIATION OF IMMUNE RESPONSE IN INTESTINE
    A. Bykov, A. Karaulov, D. Tsomartova, N. Kartashkina, V. L. Goriachkina, S. Kuznetsov, D. A. Stonogina, Y. Chereshneva · 2018 · Russian Journal of Infection and Immunity
  17. Human immunodeficiency virus type 1 (HIV-1) protease inhibitors block cell-to-cell HIV-1 endocytosis in dendritic cells
    Claudia Muratori, Eliana Ruggiero, Antonella Sistigu, Roberta Bona, Maurizio Federico · 2009 · Journal of General Virology
  18. Utilization of Laser Capture Microdissection Coupled to Mass Spectrometry to Uncover the Proteome of Cellular Protrusions
    Ana Gordon, Karine Gousset · 2021 · Methods in molecular biology
  19. [Tunneling nanotube formation in HIV-1-infected human macrophages: building bridges for efficient HIV-1 dissemination during co-infection with Mycobacterium tuberculosis].
    Shanti Souriant, Maeva Dupont, O. Neyrolles, I. Maridonneau-Parini, Geanncarlo Lugo-Villarino, C. Vérollet · 2019 · Medecine sciences : M/S
  20. Biological evolution based on nonrandom variability regulated by the organism
    Alexey M. Olovnikov · 2009 · Biochemistry (Moscow)
  21. T-cell dysfunction in HIV-1 infection: targeting the inhibitors
    Jocelyn S. Downey, N. Imami · 2010 · HIV Therapy
  22. Tunneling nanotubes provide a novel route for SARS-CoV-2 spreading between permissive cells and to non-permissive neuronal cells
    A. Pepe, S. Pietropaoli, M. Vos, G. Barba-Spaeth, C. Zurzolo · 2021 · bioRxiv
  23. Abstract B69: Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
    J. Pasquier, Bella S. Guerrouahen, H. Althawadi, Nadine Abu Kaoud, M. Maleki, F. Le Foll, A. Rafii · 2013 · Clinical Cancer Research
  24. HIV heart inflammation is mediated by HIV infected myeloid cells, HIV-tat secretion, and aberrant function of Connexin43-containing channels
    D. Ajasin, Sophia Arredondo-Anez, Jose A. Gutierrez, Michelle C. Ward, Karen Maass, E. Eugenin · 2026 · Scientific Reports
  25. Breaking cellular boundaries: molecular mechanisms of tunneling nanotube formation and fusion
    Sevan Belian, Chiara Zurzolo · 2026 · Biochemical Society Transactions
  26. Myosin-X Acts Upstream of L-Plastin to Drive Stress-Induced Tunneling Nanotubes
    Ana Melva Ramírez Pérez, J. Tovar, Karine Gousset · 2026 · Cells
  27. Induction of tunnelling nanotube-like structures by influenza A viruses requires the onset of apoptosis
    Daniel Weir, Calum Bentley-Abbot, Jack McCowan, C. Loney, Ed W. Roberts, Edward Hutchinson · 2025 · PLoS Pathogens
  28. Quantifying Impact of HIV Receptor Surface Density Reveals Differences in Fusion Dynamics of HIV Strains
    Anthony Gerg, H. Dobrovolny · 2025 · Viruses
  29. Modulation of connexin 43 in viral infections
    Harry Scott, P. Martin, S. V. Graham · 2024 · Tumour Virus Research
  30. Long actin-based cellular protrusions as novel evidence of the cytopathic effect induced in immune cells infected by the ectromelia virus
    L. Szulc-Dąbrowska, K. Gregorczyk-Zboroch, J. Struzik, Z. Wyżewski, A. Ostrowska, F. Toka, M. Gieryńska · 2018 · Central European Journal of Immunology
  31. Tunneling nanotubes contribute to the stroma-mediated imatinib resistance of leukemic cells
    Marta D Kolba, Wioleta Dudka, M. Zaręba-Kozioł, Agata Kominek, P. Ronchi, Laura Turos, J. Włodarczyk, Y. Schwab, D. Cysewski, Katja Srpan et al. · 2018 · bioRxiv
  32. Cellular communication via directed protrusion growth: Critical length-scales and membrane morphology
    Hai-Jiang Zhang, A. Kim, Shi-Jun Xu, G. Jeffries, A. Jesorka · 2015 · Nano Commun. Networks
  33. Intercellular Communication Through Contacts Between Continuous Pseudopodial Extensions in a Macrophage-like Cell Line
    Gerardo Arrevillaga-Boni, M. Hernández-Ruiz, E. C. Castillo, V. Ortiz-Navarrete · 2014 · Cell Communication & Adhesion
  34. A two population model of prion transport through a tunnelling nanotube
    I. Kuznetsov, A. V. Kuznetsov · 2014 · Computer Methods in Biomechanics and Biomedical Engineering
  35. Participation of Membrane Nanotubes in Intercellular Communication
    Agnieszka Knopik-Skrocka, Agata Śniegowska · 2014 · Postepy Biologii Komorki
  36. Emerging Swine Viruses
    Zhen-Hai Chen, A. Jongkaewwattana, Jing-Yun Ma, C. Perfumo, Daniel R. Pérez, A. Pereda · 2020 · Frontiers Research Topics
  37. Membrane Microvesiculation and its Suppression
    V. Kralj-Iglič · 2015
  38. A minimal model of prion transport through a tunneling nanotube
    I. Kuznetsov, A. Kuznetsov · 2012 · Nanotube Therapy
  39. Tunneling nanotubes: a new dimension of intercellular communication and recent progress
    Xin-Yu Dong, Yan Xuan, Mu-Ning Wang, Si-Yao Chang, Xue-Song Hu, Zhi-Yang Han · 2026 · Cell Communication and Signaling
  40. Snapshot on Cell-to-Cell Communication Nanotubes: From Bacteria to Humans
    Loredana Moro · 2026 · Biology
  41. Tunneling nanotubes induced by pseudorabies virus facilitate viral transmission in neuronal cells to evade the immune system
    Yan Kuang, Si-Qi Fan, Huihui Guo, Haojie Wang, Yafei Li, Hao Zhang, Shaomeng Liu, Dang Wang, Huan-Chun Chen, Qingyun Liu et al. · 2026 · Cell communication and signaling : CCS
  42. Tunneling nanotubes provide a new route for bovine viral diarrhea virus spreading
    Jiying Yin, Zehui Zhou, Ning He, Hongming Zhou, Xiaoqun Liu, Yi-Xing Zhao, Long-Ge Zhao, Jia-Ting Zhang, Yanan Zhu, Ying Zong et al. · 2025 · Frontiers in Veterinary Science
  43. Insect Gap Junctions Could Be a Potential Target for Pest Management
    P. Sharma, Nitika Negi, Himanshu Thakur, Jabez Raju Battu, M. Turnbull · 2022 · Annals of the Entomological Society of America
  44. Potential role of nanotubes in context of clinical treatments?
    Julia Ranzinger, Amin Rustom, Vedat Schwenger · 2013 · Communicative & Integrative Biology
  45. Tunneling nanotubes in the nervous system: The fourth pillar of brain connectivity
    Dimitri Budinger, Michael Thomas Heneka · 2026 · Neuron
  46. Tunneling nanotube-mediated intercellular spread of SARS-CoV-2 variants in epithelial cells reveals a host-targeted antiviral vulnerability.
    Gurleen Kaur, R. Khatri, Varun Kumar, Bharat Lohiya, Akanksha Chauhan, Sweety Samal · 2026 · International Journal of Biochemistry and Cell Biology
  47. Hijacking and subversion of macrophage antiviral functions by viruses
    Zhen Xu, Fengyang Shi, Jun Han, Lei Zhou, Hanchun Yang · 2026 · Virulence
  48. HIV corruption of the Arp2/3-Cdc42-IQGAP1 axis to hijack cortical F-Actin to promote cell-cell viral spread
    A. Aggarwal, Alberto Ospina Stella, Catherine Henry, Kedar Narayan, S. Turville · 2019 · bioRxiv
  49. Role of tunneling nanotube crosstalk with distressed cardiomyocytes in controlling the heart repair potential of mesenchymal stromal cells
    Anne‐Marie Rodriguez, Meriem Mahrouf‐Yorgov · 2016 · Wiley eBooks
  50. Characterization of HIV trafficking and DC-SIGN-mediated cytoskeleton rearrangement en the context of HIV transfer across dentritic cells-T lymphocytes infectious synapses
    Damjan S. Nikolic · 2012
  51. The physiological roles and pathological implications of metabolic communication via tunneling nanotubes in immune cells.
    Bing-Nan Chen, Di Wang, Ruo-Han Hu, Xiao-Bo Zhou, Hua Zhang · 2026 · The FEBS Journal
  52. Emergence of tunneling nanotube-like intervesicular connections
    S. Park, Sang-Ho Lee, Chang Ho Kim, Cheng-Ying Yin, Xue Ke, Liang-Fei Tian, Kwan-Woo Shin · 2026 · bioRxiv
  53. Morphofunctional changes in the gut-associated lymphoid tissue in rats at different stages of Trichinella infection
    O. Zhdanova, O. Chasovskikh, A. Uspensky, A. I. Russkikh, D. V. Rassokhin · 2026 · Russian Journal of Parasitology
  54. Implications of virus-induced stress granules in tauopathies
    Snigdda Sharma, Alex Vandenakker, Claudia Mariana Cortes-Pérez, Sarah Milne, Renée N. Douville · 2026 · Translational Neurodegeneration
  55. The kidney diseases associated with HIV infection and coinfection with viral hepatitis B and C. Case report
    A. Martynov, S. A. Krivushkin, M. M. Irkabaeva, Darya O. Cherenkova · 2024 · Consilium Medicum
  56. Lymphocytic choriomeningitis arenavirus utilises tunnelling nanotube-like intercellular connections for cell-to-cell spread
    Owen Byford, A. Shaw, Hiu Nam Tse, Alex Moon-Walker, E. Saphire, Sean P. J. Whelan, M. Stacey, R. Hewson, J. Fontana, J. Barr · 2023 · bioRxiv
  57. An in situ quantitative map of initial human colorectal HIV transmission
    H. Baharlou, Nicolas P. Canete, Erica E. Vine, Kevin B. Hu, Di Yuan, K. Sandgren, Kirstie M. Bertram, N. Nasr, J. Rhodes, M. Gosselink et al. · 2022 · bioRxiv
  58. New efficient intercellular spread mode of respiratory syncytial virus contributes to neutralization escape and persistence
    Wei Zhang, Xue Lin, Lu-Jing Zhang, Li Chen, Yong-Peng Sun, Junyu Si, Min Zhao, Guangxuan Wu, Luting Zhan, Ying-Bin Wang et al. · 2022 · bioRxiv
  59. Global analysis of human-to-mouse contact-dependent intercellular mRNA and lncRNA transfer in cell culture
    S. Dasgupta, Daniella Y. Dayagi, Gal Haimovich, E. Wyler, T. Olender, R. Singer, M. Landthaler, J. Gerst · 2021 · bioRxiv
  60. Endotel Hücreleri Arasında Nanotüp Tünellemenin ve Organel İletiminin Görüntülenmesi
    Bilge Özerman Edis · 2021 · Uludağ Üniversitesi Tıp Fakültesi Dergisi
  61. Identification of novel factors involved in the exacerbation of HIV-1 infection and spread among macrophages in the tuberculosis context
    Maeva Dupont · 2019
  62. Gap Junctions in Antigen-Presenting Cells
    Pablo José Sáez, Kenji F. Shoji, Juan Carlos Sáez · 2013 · CRC Press eBooks
  63. Forces and fluctuations in planar, spherical and tubular membranes
    Camilla Barbetta · 2010 · arXiv (Cornell University)
  64. HIV Exacerbates Atherosclerosis by Altering Macrophage Function
    Javier Lozano-Gerona, Jonathan Yap, Selena Vanapruks, Jason S. Irei, Tianmai Bishop, William A. Boisvert · 2026 · CardioMetabolic Syndrome Journal