Gli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling
Niewiadomski, Pawel, Kong, Jennifer H., Ahrends, Robert, Ma, Yan, Humke, Eric W., Khan, Sohini, Teruel, Mary N., Novitch, Bennett G. +1 more·2014·Cell Reports
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- Functional analysis of missense mutations in GLI2 and GLI3 involved in congenital heart diseaseRui Peng, Lei Lu, Bingkun Lei, Hongyan Wang, Xiao-Ying Yao · 2022 · Reproductive and Developmental Medicine
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- Cilia on the Brain: Primary Cilia and Their Roles in Brain FunctionSarah M. Guadiana, Elizabeth Ann Grove · 2015 · Encyclopedia of Life Sciences
- GPR17 is an Essential Component of the Negative Feedback Loop of the Sonic Hedgehog Signalling Pathway in Neural Tube DevelopmentAtsuki Yatsuzuka, Akiko Hori, Minori Kadoya, M. Matsuo‐Takasaki, T. Kondo, Noriaki Sasai · 2018 · bioRxiv
- GLI3 Processing by the Primary Cilium Regulates Muscle Stem Cell Entry into G AlertCaroline E. Brun, Marie‐Claude Sincennes, Alexander Y. Lin, Derek T. Hall, William Jarassier, Peter Feige, Morten Ritso, Fabien Le Grand, Michael A. Rudnicki · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Spatial ciliary signaling regulates the dorsal/ventral regionalization of human brain organoidsIssei S. Shimada, Akari Goto, Yutaka Hashimoto, Hiroshi Takase, Masayuki Itoh, Yoichi Kato · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The interaction between Hedgehog/Patched and Ras signaling in RhabdomyosarcomaNicole Cuvelier · 2016
- Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass SpectrometryRobert Ahrends, Paweł Niewiadomski, Mary N. Teruel, Rajat Rohatgi · 2015 · Methods in molecular biology
- Hedgehog Signaling in Gastrointestinal Morphogenesis and MorphostasisB. Florien Westendorp, Willemijn Alexandra van Dop, Gijs R. VAN DEN BRINK · 2018 · Elsevier eBooks
- Resistance to Targeted Therapy in Sonic Hedgehog Subgroup Medulloblastoma: Mechanisms and Treatment StrategiesEkaterina Pak · 2016 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
- NOVEL ROLES OF THE CILIARY GENES, THM1 AND THM2, IN ADIPOGENESIS, SKELETAL DEVELOPMENT, AND SPERMATOGENESISBailey A. Allard · 2017 · KU ScholarWorks (The University of Kansas)
- Role of RAS signaling in Hedgehog-associated embryonal rhabdomyosarcomaJulia Bauer · 2019
- Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migrationEd Zandro M. Taroc, Ankana Naik, Jennifer M. Lin, Nicolas B. Peterson, David L. Keefe, Elizabet Genis, Gabriele Fuchs, Ravikumar Balasubramanian, Paolo E. Forni · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Role of primary cilia-mediated signaling in human and mouse models of Autosomal Dominant Polycystic Kidney DiseaseLuciane M. Silva · 2018 · KU ScholarWorks (The University of Kansas)
- THE ROLE OF GLI3 IN INFLAMMATIONStephan Josef Matissek · 2020 · University of New Hampshire Scholars Repository (University of New Hampshire at Manchester)
- Investigating the Role of GLI3 Repressor in Human Kidney Organoid FormationYilin Tian · 2021 · TSpace (University of Toronto)
- Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic DevelopmentShariq S. Ansari, Miriam E. Dillard, Mohamed Ghonim, Yan Zhang, Daniel P. Stewart, Robin Canac, Ivan P. G. Moskowitz, William C. Wright, Christina A. Daly, Shondra M. Pruett‐Miller et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survivalSerhiy Havrylov, Armin M. Gamper, Ordan J. Lehmann · 2026 · eLife
- Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survivalSerhiy Havrylov, Armin M. Gamper, Ordan J. Lehmann · 2025 · eLife
- Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survivalSerhiy Havrylov, Armin M. Gamper, Ordan J. Lehmann · 2025 · eLife
- Trps1 enhances Hdac4 and Gli3 protein stability and nuclear localization independent of PKA and PP2A signalingManuela Wuelling, Lara M Janz, Anja B Ende, Nina Schulze, Andrea Vortkamp · 2025 · Cellular Signalling
- AlphaFold3 predictions of novel GLI-SUFU interfaces identify binding-defective SUFU missense variants from medulloblastoma and Gorlin syndrome patientsA. Bardwell, Umaima Arif, F. Muhammad, Celeste N. Salinas Auris, Lee Bardwell · 2026 · bioRxiv
- Trisomy 21 alters ciliary localization of Sonic Hedgehog signaling proteinsWolfgang E. Schleicher, Bailey L McCurdy, Cayla E Jewett, Chad G. Pearson · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axisChangle Zhao, Ya'nan Chen, Lei Liu, Xiang Liu, Hesheng Xiao, Feilong Wang, Qin Huang, Xiangyan Dai, Wenjing Tao, Deshou Wang et al. · 2026 · eLife
- Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axisChangle Zhao, Ya'nan Chen, Lei Liu, Xiang Liu, Hesheng Xiao, Feilong Wang, Qin Huang, Xiangyan Dai, Wenjing Tao, Deshou Wang et al. · 2026 · eLife
- Implication de la voie Hedgehog dans la mastocytose : apport de l'étude génétique de formes rares de mastocytoses à début pédiatriqueLaura Polivka · 2020
- Modélisation de pathologies neuromusculaires par la co-différenciation dirigée de cellules souches pluripotentes induites, en fibres musculaires innervées par des motoneuronesKilian Mazaleyrat · 2020
- Patched as a new target for adrenocortical carcinoma treatmentAnida Hasanovic · 2018
- Rôle de la voie de signalisation Sonic Hedgehog dans les cellules Glast positives du cerveau de souris adulteLinda Tirou · 2020
- Endosulfan rewires GSK3β to disrupt primary cilia-dependent Hedgehog signallingRavikant Piyush, Himani Barmola, Anwesha Bhattacharjya, Abhinn Gupta, Prasenjit Bhaumik, Sathees C. Raghavan, Bibha Choudhary, Sudarshan Gadadhar, Satyanarayan Rao, Swapnil Rohidas Shinde · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Conformational activation of GSK3β by an environmental toxicant suppresses hedgehog signalling and disrupts ciliary homeostasisRavikant Piyush, Himani Barmola, Anwesha Bhattacharjya, Abhinn Gupta, Prasenjit Bhaumik, Sathees C. Raghavan, Bibha Choudhary, Sudarshan Gadadhar, Satyanarayan Rao, Swapnil Rohidas Shinde · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- DHA elongates the neuronal primary cilium through GPR40-mediated signalingKento Karita, Mariko Yokota, Yuzuki Toyonaga, Riko Takase, Naoyuki Inagaki, Maki K. Yamada, Ikuko Yao, Manami Toriyama, Michinori Toriyama · 2026 · Frontiers in Cell and Developmental Biology
- Wdpcp affects skeletogenesis via the hedgehog pathwayMark T. Langhans · 2015 · D-Scholarship@Pitt (University of Pittsburgh)