Gli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling

Niewiadomski, Pawel, Kong, Jennifer H., Ahrends, Robert, Ma, Yan, Humke, Eric W., Khan, Sohini, Teruel, Mary N., Novitch, Bennett G. +1 more·2014·Cell Reports

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  18. Role of RAS signaling in Hedgehog-associated embryonal rhabdomyosarcoma
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  22. Investigating the Role of GLI3 Repressor in Human Kidney Organoid Formation
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  23. Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic Development
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  28. AlphaFold3 predictions of novel GLI-SUFU interfaces identify binding-defective SUFU missense variants from medulloblastoma and Gorlin syndrome patients
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  29. Trisomy 21 alters ciliary localization of Sonic Hedgehog signaling proteins
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  30. Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis
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  37. Conformational activation of GSK3β by an environmental toxicant suppresses hedgehog signalling and disrupts ciliary homeostasis
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  39. Wdpcp affects skeletogenesis via the hedgehog pathway
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