Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis

Vila, Isabelle K., Badin, Pierre-Marie, Marques, Marie-Adeline, Monbrun, Laurent, Lefort, Corinne, Mir, Lucile, Louche, Katie, Bourlier, Virginie +11 more·2014·Cell Reports

Cited by (165)

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  3. La fibrose du tissu adipeux
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  4. Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis
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  6. New perspectives on obesity-induced adipose tissue fibrosis and related clinical manifestations
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  7. Meta-fibrosis links positive energy balance and mitochondrial metabolism to insulin resistance
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  8. Toll‑like receptor 2 mediates deposition of collagen I in adipose tissue of high fat diet‑induced obese mice
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  9. Aberrant Mesenteric Adipose Extracellular Matrix Remodelling is Involved in Adipocyte Dysfunction in Crohn’s Disease: The Role of TLR-4-mediated Macrophages
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  10. Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling
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  11. Unraveling the complex roles of macrophages in obese adipose tissue: an overview
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  12. Muscle Arnt/Hif1β Is Dispensable in Myofiber Type Determination, Vascularization and Insulin Sensitivity
    Pierre-Marie Badin, Danesh H. Sopariwala, Sabina Lorca, Vihang A. Narkar · 2016 · PLoS ONE
  13. Toll-like receptors in B cells and obesity
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  14. The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice
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  15. Increased Fibrosis in White Adipose Tissue of Male and Female bGH Transgenic Mice Appears Independent of TGF-β Action
    Stephen Robert Clyde Bell, Jonathan A Young, Edward Owen List, Reetobrata Basu, Delaney K. Geitgey, Grace Lach, Kevin Y. Lee, Deborah Swegan, Lydia J. Caggiano, Shigeru Okada et al. · 2023 · Endocrinology
  16. Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity
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  17. Berberine ameliorates mesenteric vascular dysfunction by modulating perivascular adipose tissue in diet-induced obese in rats
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  18. Nutritional Regulation of Mammary Tumor Microenvironment
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  19. Diet-Induced Early Inflammatory Response of Visceral Adipose Tissue in Healthy Male Wistar Rats
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  20. Time-Restricted Feeding Attenuates Adipose Tissue Inflammation and Fibrosis in Mice Under Chronic Light Exposure
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  21. Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner
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  22. RETRACTED: PFKFB3, a key glucose metabolic enzyme regulated by pathogen recognition receptor TLR4 in liver cells
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  23. Fibrocytes enhance mammary gland fibrosis in obesity
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  24. Effects of Porphyromonas gingivalis Bacteria on Inflammation, Oxidative Stress and Lipid Metabolism in Models of Obese db/db Mice and 3T3-L1 Adipose Cells
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  25. Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism
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  26. Salvia hispanica L. (chia) seed have beneficial effects upon visceral adipose tissues extracellular matrix disorders and inflammation developed in a sucrose-rich diet-induced adiposity rodent model
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  27. The adipocyte apolipoprotein M is negatively associated with inflammation
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  28. Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease
    Phillip Gu, Shishir Dube, Norman H Gellada, So Yung Choi, Susan Win, Yoo Jin Lee, Shaohong Yang, Talin Haritunians, GIL Y. MELMED, Eric A. Vasiliauskas et al. · 2024 · World Journal of Gastrointestinal Surgery
  29. Lysozyme Gene Expression in 3T3-L1 Cells Sustains Expression of Adipogenic Genes and Adipocyte Differentiation
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  30. Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity
    Jiahui Liu, Ali Hussainy Zaidi, Christian J. Pike · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Innate immune signalling in the adipocyte
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  34. Hepatocyte-specific RIG-I loss attenuates metabolic dysfunction-associated steatotic liver disease in mice via changes in mitochondrial respiration and metabolite profiles
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  35. Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue
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  36. Molecular Mechanisms Underlying Obesity-Induced Chronic Inflammation
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  37. Fibulin-7 in progenitor cells promotes adipose tissue fibrosis and disrupts metabolic homeostasis in obesity
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  38. A Hydrogel Culture System Regulates Human Adipocyte Function
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  39. Growth hormone causes reversible fibrosis in muscle and fat: a study in patients with acromegaly
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  40. Toll-like receptor 4 signaling links cytoskeletal remodeling to lipid accumulation in macrophages
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  41. Impact of Inflammation and Innate Immunity Response in Obesity Mediated Diabetes
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  42. Tissu adipeux blanc
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  43. Obesity-elicited macrophages shape CD9 hi progenitor fate to promote adipose tissue fibrosis and dysfunction
    Haoussa Askia, Sébastien Dussaud, Marina C. Oliveira, A. C. Oliveira, Lucie Poupel, Clémentine Rebière, Melissa Ouhachi, Raoul Manuel, Fatiha Merabtene, Laurent Genser et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Isoliquiritigenin: A Unique Component That Attenuates Adipose Tissue Inflammation and Fibrosis by Targeting the Innate Immune Sensors
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  45. THE ROLE OF THE INTESTINAL MICROBIOTA IN THE MODULATION OF FOOD INTAKE AND BODY WEIGHT
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  46. Obesity: A Complex Disease with Immune Components
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  47. Diet, Microbioma, and Diabetes in Aging
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  48. Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors During Obesity-Induced Adipose Tissue Fibrosis
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  49. The cyclin dependent kinase inhibitor Roscovitine reverses diet- induced metabolic disruption in obese mice
    Nabil Rabhi, Kathleen Desevin, Briana Noel Cortez, Ryan Matthew Hekman, Jean Z. Lin, Andrew Emili, Stephen R. Farmer · 2021 · Research Square
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  51. Additional file 5 of Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis
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  52. Additional file 4 of Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis
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  54. Additional file 6 of Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis
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