Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes

Gkogkas, Christos G., Khoutorsky, Arkady, Cao, Ruifeng, Jafarnejad, Seyed Mehdi, Prager-Khoutorsky, Masha, Giannakas, Nikolaos, Kaminari, Archontia, Fragkouli, Apostolia +7 more·2014·Cell Reports

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    Aarti Tiwari, Saloni Rahi, Sidharth Mehan · 2020 · Current Drug Targets
  2. Circadian activities of the brain MNK‐eIF4E signalling axis contribute to diurnal rhythms of some cognitive functions
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  3. Medicinal chemistry approaches to target the MNK–eIF4E axis in cancer
    Ann Fernandez, Paige J. Monsen, Leonidas C. Platanias, Gary E. Schiltz · 2023 · RSC Medicinal Chemistry
  4. Impact of matrix metalloproteinase-9 overexpression on synaptic excitatory transmission and its plasticity in rat CA3-CA1 hippocampal pathway.
    Grzegorz Wiera, Marcin Szczot, Tomasz Wójtowicz, Katarzyna Lebida, Paulina Koza, Jerzy Wladyslaw Mozrzymas · 2015 · PubMed
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  6. eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance
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  12. A Hydroxypyrone-Based Inhibitor of Metalloproteinase-12 Displays Neuroprotective Properties in Both Status Epilepticus and Optic Nerve Crush Animal Models
    Jonathan Vinet, Anna‐Maria Costa, Manuel Salinas‐Navarro, Giuseppina Leo, Lieve Moons, Lut Arckens, Giuseppe Biagini · 2018 · International Journal of Molecular Sciences
  13. A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice
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  14. Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1
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    Litian Yin, Fengqing Li, Jue Li, Xiaorong Yang, Xiaoyan Xie, Linyuan Xue, Yanli Li, Ce Zhang · 2019 · Neurochemical Research
  16. Neuroligins in neurodevelopmental conditions: how mouse models ofde novomutations can help us link synaptic function to social behavior
    Tobias T. Pohl, Hanna Hörnberg · 2022 · Neuronal Signaling
  17. Of local translation control and lipid signaling in neurons
    Hervé Moine, Nicolas Vitale · 2018 · Advances in Biological Regulation
  18. Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge
    Simone Carotti, Maria Zingariello, Maria Angela Francesconi, Laura D’Andrea, Maria Ujue Latasa, Leticia Colyn, Maite G. Fernández‐Barrena, Rocco Simone Flammia, Mario Falchi, Daniela Righi et al. · 2021 · Oncogene
  19. Translation from the Ribosome to the Clinic: Implication in Neurological Disorders and New Perspectives from Recent Advances
    Kelvin K. Hui, YiKai Chen, Ryo Endo, Motomasa Tanaka · 2019 · Biomolecules
  20. The Potential of Cylindromatosis (CYLD) as a Therapeutic Target in Oxidative Stress-Associated Pathologies: A Comprehensive Evaluation
    Zhenzhou Huang, Yanjie Tan · 2023 · International Journal of Molecular Sciences
  21. Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome
    Mittal Jasoliya, Heather L. Bowling, Ignacio Cortina Petrasic, Blythe P Durbin-Johnson, Eric Klann, Aditi Bhattacharya, Randi Jenssen Hagerman, Flora Tassone · 2020 · Brain Sciences
  22. Therapeutic targeting of eukaryotic initiation factor (eIF) 4E
    Jerry Pelletier, Nahum Sonenberg · 2023 · Biochemical Society Transactions
  23. mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS
    Vipendra Kumar, Kwan Young Lee, Anirudh Acharya, Matthew S Babik, Catherine A. Christian, Justin S. Rhodes, Nien‐Pei Tsai · 2024 · EMBO Molecular Medicine
  24. Alteration of synaptic protein composition during developmental synapse maturation
    Takeshi Kaizuka, Toru Takumi · 2024 · European Journal of Neuroscience
  25. Persistent changes in the dorsal root ganglion nociceptor translatome governs hyperalgesic priming in mice: roles of GPR88 and Meteorin
    Ishwarya Sankaranarayanan, Moeno Kume, Ayaan Mohammed, Juliet M. Mwirigi, Nikhil Nageshwar Inturi, Gordon Munro, Kenneth Ahrend Petersen, Diana Tavares‐Ferreira, Theodore John Price · 2025 · Pain
  26. Targeted therapy of cognitive deficits in fragile X syndrome
    Alicja Puścian, Maciej J. Winiarski, Joanna Borowska, Szymon Łęski, Tomasz Górkiewicz, Mayank Chaturvedi, Klaudia Nowicka, Maria Wołyniak, Joanna J. Chmielewska, Tomasz Nikolaev et al. · 2022 · Molecular Psychiatry
  27. The tetrapartite synapse in neuropsychiatric disorders: Matrix metalloproteinases (MMPs) as promising targets for treatment and rational drug design
    Adriano José Maia Chaves Filho, Melina Mottin, Deniele Bezerra Lós, Carolina Horta Andrade, Danielle S. Macêdo · 2022 · Biochimie
  28. Od c-Fos do MMP-9 w kontroli plastyczności synaptycznej zdrowego i chorego umysłu, spojrzenie osobiste
    Leszek Kaczmarek · 2018 · Postępy Biochemii
  29. A metabolite of endophytic fungus Cadophora orchidicola from Kalimeris indica serves as a potential fungicide and TLR 4 agonist
    L. Wang, Jia‐Wei Shen, L. Xu, Jianqing Gao, C. Zhang, Yating Wang, Fengyang Chen · 2019 · Journal of Applied Microbiology
  30. MNK1 and MNK2 Expression in the Human Dorsal Root and Trigeminal Ganglion
    Stephanie I. Shiers, James J. Sahn, Theodore John Price · 2023 · Neuroscience
  31. Ozanimod differentially preserves human cerebrovascular endothelial barrier proteins and attenuates matrix metalloproteinase-9 activity following in vitro acute ischemic injury
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  32. RNA ‐binding proteins in pain
    Patrick R. Smith, Zachary T. Campbell · 2024 · Wiley Interdisciplinary Reviews - RNA
  33. Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer
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  34. Clinical significance of matrix metalloproteinase-9 in Fragile X Syndrome
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  35. The mGluR Theory of Fragile X: From Mice to Men
    Laura J. Stoppel, Emily K. Osterweil, Mark F. Bear · 2017 · Elsevier eBooks
  36. A new strategy to uncover fragile X proteomic biomarkers using the nascent proteome of peripheral blood mononuclear cells (PBMCs)
    Olivier Dionne, François Corbin · 2021 · Scientific Reports
  37. Translating from cancer to the brain: regulation of protein synthesis by eIF4F
    Ilona R. Kats, Eric Klann · 2019 · Learning & Memory
  38. Neurobehavioral features and targeted treatments in fragile X syndrome: Current insights and future directions
    Dejan B. Budimirovic, Phan Q. Duy · 2015 · Engrami
  39. Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation
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    Elpida Statoulla, K. Chalkiadaki, Dimitris Karozis, C. Gkogkas · 2021 · Cellular Signalling
  43. Translation regulation in the spinal dorsal horn – A key mechanism for development of chronic pain
    Shannon N. Tansley, Calvin Wong, Sonali Uttam, Jeffrey S. Mogil, Arkady Khoutorsky · 2018 · Neurobiology of Pain
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    Alice Romagnoli, Daniele Di Marino · 2021 · Frontiers in Psychiatry
  49. The cleavage of host cell proteins by HIV-1 protease.
    Václav Snåšel, I. (Iva) Pichová · 1996 · PubMed
  50. Neurophysiological effects of a combined treatment of lovastatin and minocycline in patients with fragile X syndrome: Ancillary results of the LOVAMIX randomized clinical trial
    Florence Morin‐Parent, Camille M. Champigny, Samantha Rae Cote, Teddy Mohamad, Seyede Anis Hasani, Artuela Çaku, François Corbin, Jean‐François Lepage · 2024 · Autism Research
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    Asma Oummadi, Géraldine Meyer-Dilhet, Amandine Béry, Arnaud Aubert, Pascal R. Barone, Stéphane Mortaud, Gilles J. Guillemin, Arnaud Menuet, Anthony Laugeray · 2019 · Journal of Neuroscience Methods
  52. Advances in understanding and targeting eIF4E activity
    Sabrina D’Agostino, Caitlin Davies, Marissa V. Powers, Paul Andrew Clarke · 2025 · Biochemical Society Transactions
  53. Strategies to Advance Drug Discovery in Rare Monogenic Intellectual Disability Syndromes
    Nuwan C. Hettige, Karla Manzano-Vargas, Malvin Jefri, Carl Ernst · 2017 · The International Journal of Neuropsychopharmacology
  54. A roadmap for neurodevelopmental disease modeling for non-stem cell biologists
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  55. Regulation of Protein Synthesis by eIF4E in the Brain
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  58. Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency
    Megha P. Subramanian, William T. Mills, Manish D. Paranjpe, Uche S Onuchukwu, Manasi Inamdar, Amanda R Maytin, Xinbei Li, Joel L. Pomerantz, Mollie K. Meffert · 2023 · iScience
  59. Alterations in auditory midbrain processing is observed in both female and male mouse model of Fragile X Syndrome
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  60. Synaptic cell adhesion molecules contribute to the pathogenesis and progression of fragile X syndrome
    Shu-Yuan Bai, De-Yang Zeng, Ming Ouyang, Yan Zeng, Wei Tan, Lang Xu · 2024 · Frontiers in Cellular Neuroscience
  61. Intracellular Signaling Networks in Fragile X Syndrome: Approaches to Drug Discovery and Therapeutics
    Christina Groß, Aditi Bhattacharya · 2017 · Elsevier eBooks
  62. Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain
    Salim Megat, Pradipta R. Ray, Jamie K. Moy, Tzu‐Fang Lou, Paulino Barragán‐Iglesias, Yan Li, Grishma Pradhan, Andi Wangzhou, Ayesha Ahmad, Robert Y. North et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  63. Pioglitazone improves deficits of Fmr1 -KO mouse model of Fragile X syndrome by interfering with excessive diacylglycerol signaling
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  66. PACAP, VIP, and ADNP: Autism and Schizophrenia
    Illana Gozes · 2016 · Current topics in neurotoxicity
  67. Serum matrix metalloproteinase-9 (MMP9) and amyloid-beta protein precursor (APP) as potential biomarkers in children with Fragile-X syndrome: A cross sectional study
    Mohamed Bekheet, Lamiaa Ali Mansour, Rasha H. Elkaffas, Mona Ahmed Kamel, Mohamed A. Elmonem · 2023 · Clinical Biochemistry
  68. How dendritic spines shape is determined by MMP-9 activity in FXS
    Magdalena Dziembowska · 2023 · International review of neurobiology
  69. Genetic and Pharmacological Reversibility of Phenotypes in Mouse Models of Autism Spectrum Disorder
    Jan C. Schroeder, Elena Deliu, Gaia Novarino, Michael J. Schmeißer · 2017 · Advances in anatomy, embryology and cell biology
  70. Matrix Metalloproteinases in Fragile X Syndrome
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  71. EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons
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  73. Recent Updates in Treatment of Diabetic Neuropathy
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  74. [Research advances in the role of mTOR signaling pathway in autism spectrum disorder].
    Guoxia Sheng, Kewen Jiang · 2019 · PubMed Central
  75. Synaptic modifications in hippocampal CA3 pyramidal cells in an Alzheimer's mouse model
    Pei Zhang · 2018
  76. Ribosome Biogenesis and its Role in Cell Growth and Proliferation in the Liver
    Katherine I. Farley‐Barnes, Susan J. Baserga · 2020
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    Deborah Levenson · 2015 · American Journal of Medical Genetics Part A
  80. FMRP and the Pathophysiology of Fragile X Syndrome
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    Megan Allen · 2017 · DigitalGeorgetown (Georgetown University Library)
  83. Regulation of Local Translation, Synaptic Plasticity, and Cognitive Function by CNOT7
    Rhonda L. McFleder · 2017 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  84. The Use of Synaptosomes in Studying Autism Spectrum Disorder and Other Neurodevelopmental Disorders
    Nadeem Murtaza, Vickie Kwan, Biren M. Dave, Karun Kar Singh · 2018 · Neuromethods
  85. Neuronal mRNA Translation in Addiction
    Emma Puighermanal, Emmanuel Valjent · 2018 · Oxford University Press eBooks
  86. De novo protein synthesis in distinct centrolateral amygdala interneurons is required for associative emotional memories
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    Emanuela Santini, Anders Borgkvist · 2020 · Oxford University Press eBooks
  88. Effective inhibition of MYC-amplified Group 3 medulloblastoma through targeting translation machinery eIF4F complex
    Yang Zhao, Tiantian Li, Shuaiwei Tian, Wei Meng, Jian Yang, Baocheng Wang, Zhuangzhuang Liang, Heng Zhao, Yipeng Han, Yujie Tang et al. · 2020
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    Ren Pengcheng, Cao Renhe, Xiayan Ye, Pang Wenbin, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Xiang Wei, Le Xiao · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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