Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling

Allen, Elizabeth, Miéville, Pascal, Warren, Carmen M., Saghafinia, Sadegh, Li, Leanne, Peng, Mei-Wen, Hanahan, Douglas·2016·Cell Reports

Cited by (221)

Items 101–200 of 221

  1. Lactate from glycolysis regulates inflammatory macrophage polarization in breast cancer
    Chao Wang, Linxuan Xue, Wenqiang Zhu, Lina Liu, Shu‐Hua Zhang, Daya Luo · 2023 · Cancer Immunology Immunotherapy
  2. Phytochemicals Target Multiple Metabolic Pathways in Cancer
    Oleg Y. Shuvalov, Yulia Kirdeeva, Alexandra A. Daks, Olga Fedorova, Sergey E. Parfenyev, Hans‐Uwe Simon, Nickolai A. Barlev · 2023 · Antioxidants
  3. ROS and radiotherapy: more we care
    Pierre Sonveaux · 2017 · Oncotarget
  4. Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL
    Lorena Fontán, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matt R. Teater, Jimmy Wilson, Jude M. Phillip, Min Xia, Shivem B. Shah, Ilkay Us et al. · 2021 · Blood
  5. Personalising and targeting antiangiogenic resistance: a complex and multifactorial approach
    María J. Bueno, Silvana Andrea Mouron, Miguel Quintela-Fandiño · 2017 · British Journal of Cancer
  6. Metabolic Remodeling as a Way of Adapting to Tumor Microenvironment (TME), a Job of Several Holders
    Jacinta Serpa · 2020 · Advances in experimental medicine and biology
  7. Effects of atorvastatin and resveratrol against the experimental endometriosis; evidence for glucose and monocarboxylate transporters, neoangiogenesis
    Ako Bahrami, Esmail Ayen, Mazdak Razi, Mehdi Behfar · 2021 · Life Sciences
  8. Different Tumor Microenvironments Lead to Different Metabolic Phenotypes
    Marjorie Justine Antonio, Anne Le · 2018 · Advances in experimental medicine and biology
  9. Reconciling environment-mediated metabolic heterogeneity with the oncogene-driven cancer paradigm in precision oncology
    Catherine Vander Linden, Cyril Corbet · 2019 · Seminars in Cell and Developmental Biology
  10. Metabolic Flexibility Is a Determinant of Breast Cancer Heterogeneity and Progression
    Marina Fukano, Morag Park, Geneviève Deblois · 2021 · Cancers
  11. Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells
    Filipa Lopes‐Coelho, Carolina Nunes, Sofia Gouveia-Fernandes, Rita Rosas, FERNANDA ATILA BARBOSA NUNES DA SILVA, Paula Gameiro, Tânia Carvalho, María Gomes da Silva, José Cabeçadas, Sérgio Dias et al. · 2017 · Oncotarget
  12. Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis
    Gaohong Sheng, Yuan Gao, Hua Kang Wu, Yang Liu, Yong Yang · 2023 · Journal of Orthopaedic Surgery and Research
  13. Immunosurveillance encounters cancer metabolism
    Yu‐Ming Chuang, Sheue‐Fen Tzeng, Ping‐Chih Ho, Chin‐Hsien Tsai · 2024 · EMBO Reports
  14. Role of TKI for Metastatic Osteogenic Sarcoma
    Florence Duffaud · 2020 · Current Treatment Options in Oncology
  15. Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
    GONG Jiajing, LI Bo, LI Longjiang, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, B. LI · 2026 · Advanced Science
  16. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors
    Vincent F. Van Hée, Daniel Labar, Gwenaël Dehon, Debora Grasso, Vincent Grégoire, Giulio G. Muccioli, Raphaël Frédérick, Pierre Sonveaux · 2017 · Oncotarget
  17. Tumor Microenvironment – Selective Pressures Boosting Cancer Progression
    Sofia C. Nunes · 2020 · Advances in experimental medicine and biology
  18. Oxygen gradient and tumor heterogeneity: The chronicle of a toxic relationship
    Madhura R. Pandkar, Shruti Ganesh Dhamdhere, Sanjeev Shukla · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  19. Different Tumor Microenvironments Lead to Different Metabolic Phenotypes
    Marjorie Justine Antonio, Cissy Zhang, Anne Le · 2021 · Advances in experimental medicine and biology
  20. Oncolytic bacteria: past, present and future
    Sergio Rius‐Rocabert, Francisco Llinares, María José Pozuelo, Antonia Garcı́a, Estanislao Nistal‐Villán · 2019 · FEMS Microbiology Letters
  21. Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk
    Jerry J. Fan, Xi Huang · 2020 · Reviews of physiology, biochemistry and pharmacology
  22. Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors
    Alessia Mira, Virginia Morello, María Virtudes Céspedes, Timothy Pietro Suren Perera, Paolo Maria Comoglio, Ramón Mangues, Paolo Michieli · 2017 · Oncotarget
  23. Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells
    Zoltán Hujber, Gábor Petővári, Norbert Szoboszlai, Titanilla Dankó, Noémi Nagy, Csilla Kriston, Ildikó Krencz, Sándor Paku, Olivér Ozohanics, László Drahos et al. · 2017 · Journal of Experimental & Clinical Cancer Research
  24. From Prokaryotes to Cancer: Glutamine Flux in Multicellular Units
    Ayelet Erez, Ilana Kolodkin‐Gal · 2017 · Trends in Endocrinology and Metabolism
  25. Metabolism in the Tumor Microenvironment
    Francesca Montenegro, Stefano Indraccolo · 2020 · Advances in experimental medicine and biology
  26. MicroRNA-Mediated Metabolic Shaping of the Tumor Microenvironment
    Federico Virga, Lorena Quirico, Stefania Cucinelli, Massimiliano Mazzone, Daniela Taverna, Francesca Orso · 2021 · Cancers
  27. The acceleration of glucose accumulation in renal cell carcinoma assessed by FDG PET/CT demonstrated acquisition of resistance to tyrosine kinase inhibitor therapy
    Noboru Nakaigawa, Keiichi Kondo, Daiki Ueno, Kazuhiro Namura, Kazuhide Makiyama, Kazuki Kobayashi, Koichi Shioi, Ichiro Ikeda, Takeshi Kishida, Tomohiro Kaneta et al. · 2017 · BMC Cancer
  28. Models of Gastroenteropancreatic Neuroendocrine Neoplasms: Current Status and Future Directions
    Katharina M Detjen, Linda Hammerich, Burcin Özdirik, Münevver Demir, Bertram J. Wiedenmann, Frank Tacke, Henning Jann, Christoph Roderburg · 2020 · Neuroendocrinology
  29. lncRNA SYTL5-OT4 promotes vessel co-option by inhibiting the autophagic degradation of ASCT2
    Qing Wen, Maohua Huang, Jingwen Xie, Runyu Liu, Qun Miao, Jinjun Huang, Junqiu Zhang, Wen-Yu Lyu, Ming Qi, Chunyi Wu et al. · 2023 · Drug Resistance Updates
  30. A gene for all seasons: The evolutionary consequences of HIF-1 in carcinogenesis, tumor growth and metastasis
    Ranjini Bhattacharya, Joel S. Brown, Robert A. Gatenby, Arig Ibrahim‐Hashim · 2024 · Seminars in Cancer Biology
  31. Efficient starvation therapy with three-pathway blocking in combination with PTT/CDT for TME reversal and tumor apoptosis
    Mengchao Ding, Xiaoying Kong, Weiyan Chen, Lei Yan, He Huang, Zunzhou Lv, Peng Jiang, Ali Mu, Congcong Huang, Jinsheng Shi · 2022 · Journal of Industrial and Engineering Chemistry
  32. Design of Nanoparticles in Cancer Therapy Based on Tumor Microenvironment Properties
    Bita Mahdavi Firouzabadi, Maria Rosa Gigliobianco, Joice Maria Joseph, Roberta Censi, Piera Di Martino · 2022 · Pharmaceutics
  33. Contribution of Adipose Tissue to Development of Cancer
    Alyssa Joy Cozzo, Ashley M. Fuller, Liza Makowski · 2018 · Comprehensive physiology
  34. Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response
    Kerstin N. Timm, Brett W. C. Kennedy, Kevin Michael Brindle · 2016 · Clinical Cancer Research
  35. Potential Therapeutic Strategies for Lung and Breast Cancers through Understanding the Anti-Angiogenesis Resistance Mechanisms
    Wafaa S.H. Ramadan, Dana M. Zaher, Alaa Muayad Altaie, Iman Mamdouh Talaat, Adel B. Elmoselhi · 2020 · International Journal of Molecular Sciences
  36. Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications
    Peiting Wu, Juan Zhang, Zhengwu Jiang, Xueru Liu, Ni Jiang, Juan Zou, Xun Chen, Daichao Wu, Yukun Li · 2026 · Biomarker Research
  37. Targeting angiogenesis: Lessons from 25 years of normalizing tumor vasculature
    Sonu Subudhi, Somin Lee, Rakesh K. Jain · 2026 · Cell
  38. Diverse Stakeholders of Tumor Metabolism: An Appraisal of the Emerging Approach of Multifaceted Metabolic Targeting by 3-Bromopyruvate
    Saveg Yadav, Shrish Kumar Pandey, Yugal Goel, Mithlesh Kumar Temre, Sukh Mahendra Singh · 2019 · Frontiers in Pharmacology
  39. Untargeted and stable isotope-assisted metabolomic analysis of MDA-MB-231 cells under hypoxia
    Jie Yang, Jianhua Cheng, Bo Hang Sun, Haijing Li, Shengming Wu, Fangting Dong, Xianzhong Yan · 2018 · Metabolomics
  40. Lenvatinib in combination with everolimus in patients with advanced or metastatic renal cell carcinoma: A phase 1 study
    Nobuaki Matsubara, Yoichi Naito, Kenji Nakano, Yutaka Fujiwara, Hiroki Ikezawa, Wataru Yusa, Masayuki Namiki, Takashi Okude, Shunji Takahashi · 2018 · International Journal of Urology
  41. Role of monocarboxylate transporters in cancer immunology and their therapeutic potential
    Ferdos Faghihkhorasani, Moona Moosavi, Al‐Hasnawi Rasool Riyadh Abdulwahid, Mohammed Kavei, Soroush Karimi, Mahshid Seyed Karimi, Payam Vezvaei, Mahsa Manafi Varkiani, Amir Reza Aref, Nasim Ebrahimi · 2025 · British Journal of Pharmacology
  42. Mechanistic target of rapamycin in the tumor microenvironment and its potential as a therapeutic target for pancreatic cancer
    Yueze Liu, Mengyu Feng, Hao Chen, Gang Yang, Jiangdong Qiu, Fangyu Zhao, Zhe Cao, Wenhao Luo, Jianchun Xiao, Lei You et al. · 2020 · Cancer Letters
  43. CD44+ Circulating Tumor Endothelial Cells Indicate Poor Prognosis in Pancreatic Ductal Adenocarcinoma After Radical Surgery: A Pilot Study
    Cheng Xing, Yatong Li, Cheng Ding, Shunda Wang, Hanyu Zhang, Lixin Chen, Pengyu Li, Menghua Dai · 2021 · Cancer Management and Research
  44. Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistance
    Hiroaki Kinoh, Hitoshi Shibasaki, Xueying Liu, Tatsuya Yamasoba, Horacio Cabral, Kazunori Kataoka · 2020 · Journal of Controlled Release
  45. Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy
    Marie Winter, Amina Naït Eldjoudi, Catherine Guette, Hubert Hondermarck, Roland P. Bourette, Quentin Fovez, William Laine, Bart Ghesquière, Éric Adriaenssens, Jérôme Kluza et al. · 2023 · Neoplasia
  46. Concurrent imaging of vascularization and metabolism in a mouse model of paraganglioma under anti-angiogenic treatment
    Caterina Facchin, Mailyn Pérez-Liva, Anikitos Garofalakis, Thomas Viel, Anaïs Certain, Daniel Balvay, Thulaciga Yoganathan, Justine Woszczyk, Kelly De Sousa, Joevin Sourdon et al. · 2020 · Theranostics
  47. Mechanisms of Resistance in Gastroenteropancreatic Neuroendocrine Tumors
    Chanjuan Shi, Michael Andrew Morse · 2022 · Cancers
  48. Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging
    David E. Cohn, Aisling Forder, Erin A. Marshall, Emily A. Vucic, Greg L. Stewart, Kouther Noureddine, William Wirt Lockwood, Calum E. MacAulay, Martial D. Guillaud, Wan L. Lam · 2023 · Frontiers in Immunology
  49. Targeted anti-angiogenesis therapy for advanced osteosarcoma
    Qiao Zhang, Yuxuan Xia, Liyuan Wang, Yang Wang, Yixi Bao, Guosheng Zhao · 2024 · Frontiers in Oncology
  50. Progress in the management of endometrial cancer (subtypes, immunotherapy, alterations in PIK3CA pathway): data and perspectives
    Ana Oaknin, Alicia León‐Castillo, Domenica Lorusso · 2020 · Current Opinion in Oncology
  51. Key indexes and the emerging tool for tumor microenvironment editing.
    Xiaofeng Dai, Yi-Ni Luo, Ying Xu, Jianying Zhang · 2019 · PubMed Central
  52. Lactylation in cancer: Metabolic-epigenetic nexus and therapeutic frontiers
    Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Yishu Wang, Honglan Zhou, Yishu Wang · 2025 · Critical Reviews in Oncology/Hematology
  53. Blood Vessel Proximity Shapes Cancer Cell Metabolism
    Federico Virga, Manuel Ehling, Massimiliano Mazzone · 2019 · Cell Metabolism
  54. Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer
    Joaquim Bosch‐Barrera, Sara Verdura, José Carlos Ruffinelli, Enric Carcereny, Èlia Sais, Elisabet Cuyàs, Ramón Palmero, Eugeni López‐Bonet, A. Hernández, Glòria Oliveras et al. · 2021 · Cancers
  55. Regulation of cancer cell lipid metabolism and oxidative phosphorylation by microenvironmental acidosis
    Michala G. Rolver, Marc Severin, Stine F. Pedersen · 2024 · American Journal of Physiology-Cell Physiology
  56. Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway
    Manzila Kuerbanjiang, Lei Gu, Chunjie Xu, Wen Ting Xu, Siyuan Wen, Hanbing Xue, Qing Rong Xu · 2021 · Journal of Immunology Research
  57. A Bloody Conspiracy— Blood Vessels and Immune Cells in the Tumor Microenvironment
    Lisa Terrassoux, Hugo Claux, Salimata Bacari, Samuel Meignan, Alessandro Furlan · 2022 · Cancers
  58. 1H NMR-based metabolomics of skin squamous cell carcinoma and peri-tumoral region tissues
    Lihong Mei, Ying Li, Hongfeng Wang, Guoxiong Xu, Xuan-Guang Ye, Gao Yang · 2022 · Journal of Pharmaceutical and Biomedical Analysis
  59. Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts
    Daniele Boso, Martina Tognon, Matteo Curtarello, Sonia Anna Minuzzo, Ilaria Piga, Valentina Brillo, Elisabetta Lazzarini, Jessica Carlet, Ludovica Marra, Chiara Trento et al. · 2023 · Journal of Experimental & Clinical Cancer Research
  60. Metabolic intervention by low carbohydrate diet suppresses the onset and progression of neuroendocrine tumors
    Yu Chen, Tatsuki Yamamoto, Yura Takahashi, Tomoka Moro, Tomoko Tajima, Yukiko Sakaguchi, Naoaki Sakata, Akihiko Yokoyama, Susumu Hijioka, Akane Sada et al. · 2023 · Cell Death and Disease
  61. Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment
    Jianan Qiao, Shu-Hui Liu, Yanfeng Huang, Xiang Zhu, Chenyang Xue, Yan Wang, Hui Xiong, Jing Yao · 2024 · Journal of Colloid and Interface Science
  62. Current status and future of anti-angiogenic drugs in lung cancer
    Xuan Yan, Zhangyan Zhao, Haicheng Tang · 2023 · Clinical and Experimental Medicine
  63. Metformin exerts antileukemic effects by modulating lactate metabolism and overcomes imatinib resistance in chronic myelogenous leukemia
    Meher Bolisetti Gayatri, Rama Krishna Kancha, Dorababu Patchva, Nagaraj Velugonda, Sadashivudu Gundeti, Aramati B. M. Reddy · 2023 · FEBS Journal
  64. Mitochondria dysfunction in circulating tumor cells
    Chiara Agnoletto, Stefano Volinia · 2022 · Frontiers in Oncology
  65. Development of a broadly potent neutralizing antibody targeting Nidogen 1 effectively inhibits cancer growth and metastasis in preclinical tumor models
    Tingmao Xue, Cherlie Lot Sum Yeung, Xiaowen Mao, Sze Keong Tey, Kwok Wai Lo, Alexander Hin Ning Tang, Jing‐Ping Yun, Judy Wai Ping Yam · 2025 · Journal of Translational Internal Medicine
  66. In Situ Synthesis of an Immune-Checkpoint Blocker from Engineered Bacteria Elicits a Potent Antitumor Response
    Yuting Wei, Zhirang Zhang, Tianyuan Xue, Zhongda Lin, Xinyu Chen, Yishi Tian, Yuan Li, Zhangyan Jing, Wenli Fang, Tianliang Fang et al. · 2024 · ACS Synthetic Biology
  67. Racial disparity in metabolic regulation of cancer
    Pankaj K. Singh · 2017 · Frontiers in bioscience
  68. Isolation of Tumor Cells Based on Their Distance from Blood Vessels
    Saran Kumar, Husni Sharife, Tirzah Kreisel, Libat Bar-Lev, Myriam Grunewald, Eli Keshet · 2020 · BIO-PROTOCOL
  69. Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer
    Nicola Baldini, Angelo De Milito, Olivier Féron, Robert J. Gillies, Carine Michiels, Angela M. Otto, Silvia Pastoreková, Stine F. Pedersen, Paolo Ettore Porporato, Pierre Sonveaux et al. · 2017 · Frontiers in Pharmacology
  70. Trimming the Vascular Tree in Tumors: Metabolic and Immune Adaptations
    Elizabeth Allen, Rindert Missiaen, Gabriele Bergers · 2016 · Cold Spring Harbor Symposia on Quantitative Biology
  71. Immunometabolism characteristics and a potential prognostic risk model associated with TP53 mutations in breast cancer
    Mengping Jiang, Xiangyan Wu, Shengnan Bao, Xi Wang, Fei Qu, Qian Liu, Xiang Huang, Wei Li, Jinhai Tang, Yongmei Yin · 2022 · Frontiers in Immunology
  72. Metabolic targeting of malignant tumors: a need for systemic approach
    Aggelos T. Margetis · 2022 · Journal of Cancer Research and Clinical Oncology
  73. pH regulators of the tumoral microenvironment: A general overview
    Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar · 2020 · Elsevier eBooks
  74. Targeted Therapies in the Management of Well-Differentiated Digestive and Lung Neuroendocrine Neoplasms
    Namrata Vijayvergia, Arvind N. Dasari · 2020 · Current Treatment Options in Oncology
  75. Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer
    Jan Lisec, Dennis Kobelt, Wolfgang Walther, Margarita Mokrizkij, Carsten Grötzinger, Carsten Jaeger, Katharina Baum, Mareike Simon, Jana Wolf, Nicola Beindorff et al. · 2021 · Cancers
  76. Delineating cell behavior and metabolism of non-melanoma skin cancer in vitro
    Tatiana Mendez, Shawheen Saffari, Janet M. Cowan, Nora Laver, James Baleja, Addy Alt‐Holland · 2020 · In Vitro Cellular & Developmental Biology - Animal
  77. Killing two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors
    Catherine Vander Linden, Cyril Corbet · 2018 · Molecular & Cellular Oncology
  78. Dual inhibition of lactate transporters MCT1 and MCT4 in pancreatic neuroendocrine tumors targets metabolic heterogeneity and functional redundancy
    Konstantin Bräutigam, Janine Straub, Abdulloh K Bihi, Renaud Maire, Simona Avanthay, Kristina Fillipova, Valentina Andreasi, Anna Battistella, Philipp Kirchner, Matthias S. Dettmer et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  79. Monocarboxylate Transporters 1 and 4 and Prognosis in Small Bowel Neuroendocrine Tumors
    Niko Hiltunen, Jukka M. J. Rintala, Juha P. Väyrynen, Jan Böhm, Tuomo J. Karttunen, Heikki I. Huhta, Olli Helminen · 2022 · Cancers
  80. Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming
    Kalpana Ghimire, Bhuwan Prasad Awasthi, Kiran Yadav, Jiwoo Lee, Hyunjin Kim, Byeong‐Seon Jeong, Jung‐Ae Kim · 2025 · Chemico-Biological Interactions
  81. Antiangiogenic resistance via metabolic symbiosis
    Gabriela Jiménez-Valerio, Oriol Casanovas · 2016 · Molecular & Cellular Oncology
  82. Anti-angiogenic effect of rapamycin in mouse oxygen-induced retinopathy is mediated through suppression of HIF-1alpha/VEGF pathway.
    Yi Sun, Lei Liu, Na Cai, Ning Ning Liu · 2017 · PubMed Central
  83. Alpha-crystallin B chains in trastuzumab-resistant breast cancer cells promote endothelial cell tube formation through activating mTOR
    Lili Yang, Kazuma Higashisaka, Masafumi Shimoda, Yuya Haga, Naoki Sekine, Hirofumi Tsujino, Kazuya Nagano, Kenzo Shimazu, Yasuo M Tsutsumi · 2021 · Biochemical and Biophysical Research Communications
  84. Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
    Go J Yoshida, Arata Azuma, Yukiko Miura, Akira Orimo · 2020 · Vide Leaf, Hyderabad eBooks
  85. Anti-angiogenic Therapy-Mediated Endothelial Damage: A Driver of Breast Cancer Recurrence?
    Laura Pisarsky, Cyrus Michael Ghajar · 2018 · Advances in experimental medicine and biology
  86. In silico analysis shows slc1a4 as a potential target of hsa-mir-133a for regulating glutamine metabolism in gastric cancer
    Averi Chakraborty, Jayasree Patnaik, S Anupriya, Nandita Parida, Tithi Parija, Srinivas Patnaik · 2024 · International Journal of Biological Macromolecules
  87. Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization
    Yushuo Gao, Yisheng Zhong, Yanji Zhu, Anna Maria Demetriades, Yujuan Cai, Jikui Shen, Qing Lü, Xi Ping Shen, Bing Xie · 2018 · Journal of Ophthalmology
  88. The Influence of Mitochondrial Energy and 1C Metabolism on the Efficacy of Anticancer Drugs: Exploring Potential Mechanisms of Resistance
    Marika Frańczak, Isabel Toenshoff, Gerrit Jansen, Ryszard Tomasz Smolenski, Elisa Giovannetti, Godefridus J. Peters · 2022 · Current Medicinal Chemistry
  89. Prostate cancer cells elevate glycolysis and G6PD in response to caffeic acid phenethyl ester-induced growth inhibition
    Tzu-Ping Lin, Pei‐Chun Chen, Ching-Yu Lin, Bi‐Juan Wang, Ying‐Yu Kuo, Chien-Chih Yeh, Jen‐Chih Tseng, Chieh Huo, Cheng-Li Kao, Li‐Jane Shih et al. · 2025 · BMC Cancer
  90. Mechanistic understanding of crosstalk between blood vessels and immunity and inflammation in diseases
    Yihai Cao · 2026 · Immunity & Inflammation
  91. Targeting tumor angiogenesis and metabolism: a new perspective in pediatric thoracic tumor therapy
    Yong Lv, Fanke Shu, Dengke Luo, Ru Jia, Yidong Huang, Chang Xu · 2025 · Frontiers in Cell and Developmental Biology
  92. Resistance to antiangiogenic treatments: A review
    Tomas Koltai, Stephan J. Reshkin, Rosa Angela Cardone · 2022 · Elsevier eBooks
  93. Melanoma Metabolism
    Franziska Baenke, Nathalie S. Dhomen, Eyal Gottlieb, Richard Marais · 2019 · Springer eBooks
  94. Recent Progress in the Therapeutic Modulation of Lactate for Cancer Treatment
    Youbo Zhao, Menghuan Li, Zhong Yuan Luo, Min Su, Chao Yu · 2022 · Advanced Therapeutics
  95. Glucose starvation as cancer treatment: Thermodynamic point of view
    Ignacio Durán, J. P. Pomuceno, Martín RR, E Silva, S. Montero, Ricardo Mansilla, G. Cocho, José Manuel Nieto-Villar · 2018 · Integrative Cancer Science and Therapeutics
  96. Emerging Mechanisms of Lactate Regulation of Biological Processes
    Emma C. Fink, Edward T. Chouchani · 2025 · Annual Review of Cancer Biology
  97. Lactate Facilitates the Survival and Invasion of Pancreatic Cancer Cells Under Glucose Deprivation
    F Wang, Ping Hu, Shengbo Han, Ya Zhang, Yang Li, Wenfeng Zhuo, Yong Bo Zhao, Yan Huang, Guozheng Lv, Hongda Wang et al. · 2026 · The FASEB Journal
  98. Melanoma Metabolism
    Franziska Baenke, Nathalie S. Dhomen, Eyal Gottlieb, Richard Marais · 2019 · Springer eBooks
  99. Specific expression of lactate dehydrogenases in glioblastoma controls intercellular lactate transfer to promote tumor growth and invasion
    Joris Guyon, Ignacio Fernández‐Moncada, Claire M. Larrieu, Cyrielle L. Bouchez, Tiffanie Chouleur, Heidi Espedal, Gro Vatne Røsland, Boutaina Daher, Aurélien Barré, Benjamin Dartigues et al. · 2021 · Research Square
  100. Exploiting Cancer Cells Metabolic Adaptability to Enhance Therapy Response in Cancer
    Sofia C. Nunes · 2020 · Advances in experimental medicine and biology