Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection

Watanabe, Momoko, Buth, Jessie E., Vishlaghi, Neda, de la Torre-Ubieta, Luis, Taxidis, Jiannis, Khakh, Baljit S., Coppola, Giovanni, Pearson, Caroline A. +15 more·2017·Cell Reports

Cited by (403)

Items 301–400 of 403

  1. Gene-Edited Fluorescent and Mixed Cerebral Organoids
    Lisa Bachmann, Lucia Gallego Villarejo, Natalie Heinen, David Marks, Marcus Peters, Thorsten Müller · 2022 · The CRISPR Journal
  2. Combined Molecular Toxicity Mechanism of Phthalate Mixtures
    Yiyun Liu, De‐Sheng Pei · 2025
  3. Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology
    Yuan‐Chen Tsai, Hajime Ozaki, Xinyi Wang, Axel A. Almet, Isabel Fleming, Kaori Shiraiwa, Matthew Jung Min Noh, Caihao Nie, Sunnyana Trejo, Bret Kiyoshi Sugita et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Identification of antiviral RNAi regulators, ILF3/DHX9, recruit at ZIKV stem loop B to protect against ZIKV induced microcephaly
    Zhiwei Lei, Yu Gu, Ying Liu, Hailiang Liu, Xiaohua Lu, Weijie Chen, Lu Zhou, Pan Pan, Zhuohong Chen, Zhaoyang Yue et al. · 2025 · Nature Communications
  5. The Application and Challenges of Brain Organoids in Exploring the Mechanism of Arbovirus Infection
    Baoqiu Cui, Zhijie Wang, Anum Farid, Zeyu Wang, Kaiyue Wei, Naixia Ren, Fengtang Yang, Hong Dong Liu · 2025 · Microorganisms
  6. Brain organoids and genome editing: A new era in understanding human brain development and disorders
    Min Zhou, Yuanqing Cao, Ke Yue, Wenyu Wu, Yutong Xie, Daiyu Hu, Jingjing Zhao, Fang Xu, Jian‐Rong Guo, Zhenzhou Li et al. · 2025 · Neural Regeneration Research
  7. Bioengineering of brain organoids: Advancements and challenges
    Renjitha Gopurappilly, Rakhi Pal · 2022 · Elsevier eBooks
  8. Modeling PCDH19-CE: From 2D Stem Cell Model to 3D Brain Organoids
    Rossella Borghi, Valentina Magliocca, Marina Trivisano, Nicola Specchio, Marco Tartaglia, Enrico Bertini, Claudia Compagnucci · 2022 · International Journal of Molecular Sciences
  9. Brain organoids
    Madison R. Glass, Felix A. Kyere, Deborah L. French, Jason L. Stein, Elisa A. Waxman · 2022 · Elsevier eBooks
  10. Brain organoids for addressing COVID-19 challenge
    Jin Seok Yu, Kailun Wang, Dalin Zheng · 2022 · Frontiers in Neuroscience
  11. Shedding light on latent pathogenesis and pathophysiology of mental disorders: The potential of iPS cell technology
    Yuko Arioka, Hiroki Okumura, Hideya Sakaguchi, Norio Ozaki · 2023 · Psychiatry and Clinical Neurosciences
  12. Brain organoid-on-a-chip to create multiple domains in forebrain organoids
    Yuan‐Chen Tsai, Hajime Ozaki, Ango Morikawa, Kaori Shiraiwa, Andy Prosvey Pin, Aya Galal Salem, Kenneth Akady Phommahasay, Bret Kiyoshi Sugita, Christine Hein Vu, Saba Mamoun Hammad et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development
    Adina Sophie Graffunder, Audrey Amber Julie Bresser, Valeria Beatriz Fernández Vallone, Matthias Megges, Harald Stachelscheid, Peter Kühnen, Robert Opitz · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Cryopreservation of Human Cortical Organoids Using Vitrification
    Sandra P. Mojica-Perez, Kyle Stokes, Samantha Jacobs, Joy Huang, Shivanshi Vaid, Yukun Yuan, Caroline Alayne Pearson, Daniel Montes, Andrew M. Tidball, Debora VanHeyningen et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Alveolar organoids: development of an in vitro assay to facilitate pulmonary toxicity assessments
    Jooyeon Lee, Hyosin Baek, Seok‐Ho Hong, Jong‐Hee Lee, Seung-Jun Wang, Ji Young Lee, Myung Ha Song, Se‐Ran Yang · 2022 · Organoid
  16. Towards learning and memory risk assessment with human brain organoids: barriers and opportunities
    Ronit Mohapatra, Dowlette‐Mary Alam El Din, Hanyu Zhao, Thomas Härtung, Lena Smirnova · 2026 · Frontiers in Toxicology
  17. Morphogen-guided neocortical organoids with anteroposterior areal identity
    Yuan‐Chen Tsai, Hajime Ozaki, Axel A. Almet, Isabel Fleming, Caihao Nie, Songhao Luo, Xinyi Wang, Kaori Shiraiwa, Matthew Jung Min Noh, Sunnyana Trejo et al. · 2026 · Cell stem cell
  18. Secreted Reporter Assay Enables Quantitative and Longitudinal Monitoring of Neuronal Activity
    Ana C. Santos, Simone Chiola, Guang Yang, Aleksandr Shcheglovitov, Sungjin Park · 2021 · eNeuro
  19. A facile method to generate cerebral organoids from human pluripotent stem cells
    Susan Simorgh, Seyed Ahmad Mousavi, San Kit To, Vincent Pasque, Keimpe D. B. Wierda, Tim Vervliet, Meghdad Yeganeh, Paria Pooyan, Yoke Chin Chai, Catherine M. Verfaillie et al. · 2023 · EXCLI journal
  20. Using cortical organoids to understand the pathogenesis of malformations of cortical development
    Kellen Diamond Winden, Isabel Gisser, Mustafa Şahin · 2025 · Frontiers in Neuroscience
  21. Maximizing the utility of brain organoid models and overcoming their perceived limitations
    Tyler J. Wenzel, Darrell D. Mousseau · 2024 · Elsevier eBooks
  22. Engineering Human CNS Morphogenesis: Controlled Induction of Singular Neural Rosette Emergence
    Gavin T. Knight, Brady F. Lundin, Nisha R. Iyer, Lydia Ashton, William A. Sethares, Rebecca L. Willett, Randolph Scott Ashton · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  23. HIV-1 infection promotes neuroinflammation and neuron pathogenesis in novel microglia-containing cerebral organoids
    Srinivas D. Narasipura, Janet P. Zayas, Michelle K. Ash, Anjelica F. Reyes, Tanner L. Shull, Stéphanie Gambut, Jeffrey R. Schneider, Ramón Lorenzo-Redondo, Lena Al‐Harthi, João I. Mamede · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  24. A neurorecording toolkit for longitudinal assessments of transplanted human cortical organoids in vivo
    Kate E. Herrema, Elizabeth K. Kharitonova, Daria Bogatova, Madison N. Wilson, Emily A Martin, Clara Chung, Francesca Puppo, Shira Klorfeld-Auslender, Pierre O. Boucher, Li‐Huei Tsai et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Research insights and clinical opportunities of functional organoid-based platforms
    Yueyu Huang, Wenhui Shen, Kehan Li, Yutian Zhang, Qiao‐Li Lv, Changchun Wang, Weimin Mao, An Zhao · 2025 · Bio-Design and Manufacturing
  26. Comparison of human cerebral organoids infected with wild-type Zika versus attenuated DN-2 virus strains uncovers differences in host immune responses
    Yun Ying Choo, Tuan Zea Tan, Summer Li-Xin Zhang, Hwee Cheng Tan, Eng Eong Ooi, John Jia En Chua · 2025 · Cell Communication and Signaling
  27. Human neurogenesis
    Aparna Bhaduri, Madeline G. Andrews, Arnold R. Kriegstein · 2020 · Elsevier eBooks
  28. hiPSC disease modeling with 3D organoids
    Nathan James Cunningham, Rahulkumar Bhoi, Huaxiao Yang · 2022 · Elsevier eBooks
  29. The Brain Organoid Technology: Diversity of Protocols and Challenges
    Andrey Popatansov · 2022 · Biomedical engineering
  30. Telencephalic organoids as model systems to study cortical development and diseases
    Woo Sub Yang, Ferdi Rıdvan Kiral, In‐Hyun Park · 2024 · Organoid
  31. Functional Exploration of Epilepsy Genes in Patient-Derived Cells
    Maria Celeste Varela, Ranmal Aloka Samarasinghe, Jack M. Parent · 2024 · Oxford University Press eBooks
  32. Stem Cell-Derived Neural Organoids: From the Origin to Next Generation
    Hideya Sakaguchi, Nozomu Takata · 2024 · Springer eBooks
  33. Brain Organoids as a Model to Study Zika Virus and SARS-CoV-2 Infections
    Veronica Krenn, Luiza M. Higa, Patricia Pestana Garcez · 2022 · Neuromethods
  34. Maturation of Neuronal Activity in Caudalized Human Brain Organoids
    Svetlana M. Molchanova, Mariia Y. Cherepkova, Shamsiiat Abdurakhmanova, Suvi H. Kuivanen, Elina Pörsti, Päivi Pöhö, Jaakko Teppo, Jonna Saarimäki‐Vire, Jouni Kvist, Diego Balboa et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutation
    Kathryn R. Bowles, M. Catarina Silva, Kristen R. Whitney, Taylor B. Bertucci, Jacob C. Garza, Nathan C. Boles, Kevin H. Strang, Sidhartha K. Mahali, Jacob A. Marsh, Cynthia Chen et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Human Maternal-Fetal Interface Cellular Models to Assess Antiviral Drug Toxicity during Pregnancy
    Savannah L. Herbek, Marie C. Smithgall, Elisabeth A. Murphy, Robert E. Schwartz, Shuibing Chen, Laura E. Riley, Heidi Stuhlmann, Yawei J. Yang, Ria Goswami · 2022 · Reproductive Medicine
  37. Transcriptional changes consistent with impaired neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras
    Simone Chiola, Jingye Yang, H. M. Arif Ullah, Kandy L. Napan, Qiju Huang, Nicholas T. Gamboa, Osama A. Youssef, Howard Colman, Samuel Henry Cheshier, Alex Shcheglovitov · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  38. STAT3 regulates the generation of astroglia in human brain organoids with high mTORC1 activity
    Bipan Kumar Deb, Thomas L. Li, John D. Blair, Dirk F. Hockemeyer, Helen S. Bateup · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment
    Qiu‐Yan Xu, Yongjing Wang, Yun He, Xin-Qi Zheng, Man-Li Tong, Lin Yu, Tian‐Ci Yang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment
    Qiu‐Yan Xu, Yongjing Wang, Yun He, Xin-Qi Zheng, Man-Li Tong, Lin Yu, Tian‐Ci Yang · 2024 · eLife
  41. Weak and tunable adhesion-clutch drives rapid cell migration and glioblastoma motility
    Kentarou Baba, Ami Fukushi-Kumagaya, Megumi Morisaki, Ryosuke F. Takeuchi, Zhijie Xiao, Yoshikazu Nagashima, Mizuki Sakai, Yasuna Higashiguchi, Hiroko Katsuno‐Kambe, Asako Katsuma et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Immune-competent apical-out airway organoids reveal distinct antiviral strategies of macrophages, neutrophils, and monocytes during influenza infection
    Martin Beukema, Jacqueline J. de Vries-Idema, Nilima Dinesh Kumar, Shuran Gong, Nils Doesburg, Anke L. W. Huckriede, Barbro N. Melgert · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  43. L’édition de gènes dans la découverte du médicament et l’innovation thérapeutique
    Jean‐Luc Galzi · 2019 · médecine/sciences
  44. Brain organoids as a model system for human neurodevelopment in health and disease
    Orly Reiner, Eyal Karzbrun · 2020 · Elsevier eBooks
  45. Bioengineered Scaffold Microenvironment Promotes Assembly and Differentiation of Stem Cell-Derived Human Organoids
    Richard L. Youngblood · 2020 · Deep Blue (University of Michigan)
  46. Organoid As a Novel Technology for Disease Modeling
    Tolga Sever, Ilgin CEVIK, Gizem Calibasi‐Kocal, Ender Ellidokuz, Yasemin Başbınar · 2021 · Journal of Basic and Clinical Health Sciences
  47. 3D organotypic cell structures for drug development and Microorganism-Host interaction research
    Ekaterina V. Zubareva, Sergey V. Nadezhdin, Natalia A. Nadezhdina, Veronika S. Belyaeva, Yuriy E. Burda, Tatyana Valeryevna Avtina, Олег Сергеевич Гудырев, Inga M. Kolesnik, Svetlana Yu. Kulikova, Mikhail O. Mishenin · 2021 · Research Results in Pharmacology
  48. Advancing antiviral strategies against emerging RNA viruses by phenotypic drug discovery
    Marianna Tampere · 2021 · Figshare
  49. Design and Characterization of a Fluorescent Reporter Enabling Live-cell Monitoring of MCT8 Expression
    Adina Sophie Graffunder, Sarah Paisdzior, Robert Opitz, Kostja Renko, Peter Kühnen, Heike Biebermann · 2021 · Experimental and Clinical Endocrinology & Diabetes
  50. Pluripotent stem cell–derived brain-region-specific organoids
    Phuong Trang Nguyen, Hongjun Song, Guo‐li Ming · 2021 · Elsevier eBooks
  51. Induced pluripotent stem cell–derived neural stem cells
    Lars Roll, Andréas Faissner · 2021 · Elsevier eBooks
  52. [Facioacromelic disostosis with metal retardation (author's transl)].
    J M Cantú, A Hernández, Z Nazará-Cazorla, C Pacheco, S Armendares · 1974 · PubMed
  53. Avaliação da infecção do Zika vírus em astrócitos.
    Cristine Marie Yde Ohki · 2019
  54. Faculty Opinions recommendation of Applications of human brain organoids to clinical problems.
    Alysson Renato Muotri · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  55. Changement d’échelle entre organoïde et organe appliqué au traitement de maladies graves
    David Vauris, J. C. André · 2023 · Entropie thermodynamique – énergie – environnement – économie
  56. Stem Cell-Derived Neural Organoids: From the Origin to Next Generation
    Hideya Sakaguchi, Nozomu Takata · 2023 · Springer eBooks
  57. Assessment of The Broad-Spectrum Host Targeting Antiviral Efficacy of Halofuginone Hydrobromide in Human Airway, Intestinal and Brain Organoid Models
    Inés García-Rodríguez, Giulia Moreni, Pamela E. Capendale, Lance Mulder, Ikrame Aknouch, Renata Vieira de Sá, Nina Johannesson, Eline Freeze, Hetty W. M. van Eijk, Gerrit Koen et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  58. Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment
    Qiu‐Yan Xu, Yongjing Wang, Yun He, Xin-Qi Zheng, Man-Li Tong, Lin Yu, Tian‐Ci Yang · 2024 · eLife
  59. Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment
    Qiu‐Yan Xu, Yongjing Wang, Yun He, Xin-Qi Zheng, Man-Li Tong, Lin Yu, Tian‐Ci Yang · 2024 · eLife
  60. Additional file 1 of Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro
    Oluwafemi Solomon Agboola, Xinglin Hu, Zhiyan Shan, Yanshuang Wu, Lei Lei · 2021 · Figshare
  61. Additional file 3 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs
    Yajie Xu, Peipei Liu, Zhong-Ze Yan, Ting‐Wei Mi, Yingying Wang, Qian Li, Zhao‐Qian Teng, Chang‐Mei Liu · 2023 · Figshare
  62. Human Cerebral Organoids in Pillar/Perfusion Plates for Modeling Neurodevelopmental Disorders
    Prabha Acharya · 2024
  63. Current Trends in Brain Organoid Research: Scientific Opportunities and Challenges
    Michael J. Borrett, Rahel Kästli · 2024 · Collaborative bioethics
  64. The Brainstorm Organoid Project: A Collaboration of Bioethics and Neuroscience to Advance Brain Organoid Research
    Insoo Hyun, Jeantine E. Lunshof, John Aach, Matthew L. Baum, Parastoo Khoshakhlagh, Richie E. Kohman, Caroline Lowenthal, Aric Lu, Alex H. M. Ng, Sergiu P. Pașca et al. · 2024 · Collaborative bioethics
  65. Bringing “precision” to psychiatry: Challenges and promises
    Joseph A. Gogos · 2024 · Elsevier eBooks
  66. Etiology and Translational Research in Neurodevelopmental Disorders
    Fei Li, Mingyu Xu, Juehua Yu, Miao Yan Cao · 2024 · Springer eBooks
  67. The promise of cerebral organoids for neonatology
    Clare E. Howard, Manju Cheenath, Elizabeth Erin Crouch · 2025 · Current Opinion in Pediatrics
  68. Modeling potential drugs for Zika virus in animal and in vitro platforms: what is the current state of the art?
    Debora Santos, N.C. Oliveira, Elaine Cristina Alves Costa, Maria Vitória Ramalho Paes, Bruna Beltrão-Braga, Andrelissa Gorete Castanha, Patrícia Cristina Baleeiro Beltrão-Braga · 2025 · Expert Opinion on Drug Discovery
  69. Perspective Chapter: A New Era in Viral Research during the Pandemic – Can Organoids Serve as an Alternative to Animal Models?
    Sevda Demir, Fikrettin Şahi̇n · 2025 · Infectious diseases
  70. Zika Virus Infections
    Kristina Adachi, Natalie M. Quanquin, Claudia Raja Gabaglia, Patrícia Brasil, Karin Nielsen‐Saines · 2025 · Elsevier eBooks
  71. Organoid Technology: Disease Modeling, Drug Discovery, and Personalized Medicine
    Jyotirmoi Aich, Sangeeta Ballav, Isha Zafar, Aqdas Khan, Shubhi Singh, Manash Kumar Paul, Shine Devrajan, Soumya Basu · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  72. Neural Progenitors as a Novel Pathogenic Mechanism in Microcephaly
    Rami Yair Tshuva, Jeyoon Bok, Mio Nonaka, Xufeng Xue, Bidisha Bhattacharya, Aditya Kshirsagar, Tsviya Olender, Miri Danan-Gotthold, Tamar Sapir, Jianping Fu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  73. Brainy buds: Organoids unveiling the evolution of our nervous system
    Autumn Hudock, Maria Carolina Marchetto · 2025 · Evolution of Nervous Systems
  74. How human-induced pluripotent stem cells are derived into organoids
    Harysh Winster Suresh Babu, Nandhini Ilangovan, Sindduja MuthuKumar, Salmanul Faris, Heera Ram, Thangarasu Ravimanickam · 2025 · Elsevier eBooks
  75. Maturation of the glymphatic system confers innate resistance of the brain to Zika virus infection
    Jhulimar Guilherme Doerl, Emanuelly Karine Campos Chaves, Vivian Antonielly Becker dos Santos, Bruna Lorena de Melo Marcelino, Diego Marques Coelho, Leo M. Miyakoshi, Josélio Maria Galvão de Araújo, Selma M. B. Jerônimo, Eduardo Bouth Sequerra · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  76. Additional file 2 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs
    Xu, Ya-Jie, Liu, Pei-Pei, Yan, Zhong-Ze, 米廷伟, Wang, Ying-Ying, Li, Qian, 腾兆乾, Liu, Chang-Mei · 2023 · Figshare
  77. Additional file 1 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs
    Xu, Ya-Jie, Liu, Pei-Pei, Yan, Zhong-Ze, 米廷伟, Wang, Ying-Ying, Li, Qian, 腾兆乾, Liu, Chang-Mei · 2023 · Figshare
  78. Brain organoids as versatile models for neurotropic virus research
    Nhu Thi Quynh Mai, Byoung-San Moon · 2025 · Organoid
  79. Overcoming diffusion limits to advance brain organoids
    Xuyu Qian · 2026 · Neural Regeneration Research
  80. Cell atlases and the developmental foundations of the phenotype
    Alicia Lou, Mónica Chagoyen, Juan F. Poyatos · 2026 · PLoS Computational Biology
  81. Underscoring the Effects of Proton Radiation on Neuronal Function in 2D and 3D In Vitro Cortical Tissue Models
    Neal M. Lojek, Nazlı Seray Bostancı, Paulo H. Borges, Andrew M. Rogers, Erno Sajo, Isaac Meyer, Jan Schuemann, Egle Cekanaviciute, Bryan James Black, Chiara E. Ghezzi · 2026 · Radiation Research
  82. Protocol for characterization of spatiotemporal network dynamics in cortical and hippocampal assembloids
    Asia R. Guzman, Colin M. McCrimmon, Daniel Toker, Bennett G. Novitch, Momoko Watanabe, Ranmal Aloka Samarasinghe · 2026 · STAR Protocols
  83. Pathological modeling of tick-borne encephalitis virus infection and induced antiviral response in neurons and astrocytes using human neural progenitor-derived cells.
    Mazigh Fares · 2018
  84. Analyse histologique et fonctionnelle du développement de précurseurs neuraux dérivés de cellules souches pluripotentes induites humaines greffés dans le cortex de la souris
    Célia Raïs · 2019 · theses.fr (ABES)
  85. Mécanismes déployés par le virus Zika dans le contrôle de l’apoptose lors de l’infection
    Jonathan Turpin · 2021
  86. Generation, extraction and characterisation on brain organoid culture images with small dataset constraints
    Clara Brémond Martin · 2023 · theses.fr (ABES)
  87. Viral threats to pregnancy: Global health risks in the era of pandemics
    Guilherme de Moraes Nobrega, Amit Garg, Jean K. Lim · 2026 · Advances in virus research
  88. Migration of neural stem cells during human neocortical development
    Ryszard Wimmer · 2024 · theses.fr (ABES)
  89. Impact of the viscoelastic properties of the 3D environment on the fate of artificial stem cell spheroids
    Lucas Lemarié · 2024
  90. Advances in neural organoids: structural organization, disease modeling, and applications in gene therapy
    Evelina Nasybullina, Elvira Ruslanovna Akhmetzyanova, Albert Anatolyevich Rizvanov, Yana Olegovna Mukhamedshina · 2026 · Molecular Biology Reports
  91. Exploratory strain-associated patterns of antiviral transcriptional responses to Zika virus exposure in developing human neural tissue
    Zahra Abedi, Mohammad Ali Sheikh Beig Goharrizi, Amirreza Abbasi, Negar Sadat Soleimani Zakeri, Helia Jangi, Alireza Susanabadi · 2026 · Genomics & Informatics
  92. Expanding genetic code to generate human brain organoids with both vasculature and microglia
    Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Brain corticogenesis promotes SARS-CoV-2 neuro-glial tropism through lipid-dependent viral replication
    Byoung-San Moon, Dae‐Gyun Ahn, Jieun Park, Nhu Thi Quynh Mai, Da-Jin Jeong, Hyowon Hong, Sae‐Bom Yoon, Sunhee Lee, Gun Young Yoon, Chonsaeng Kim et al. · 2026 · Stem Cell Reports
  94. Engineering brain organoids for functional validation and translational applications: Construction strategies, vascularization, and standardization
    Guohong Huang, Chenfei Lu, Zihan Jin, Yunchuanxiang Huang, Xinya Du, Xixi Hu, Hui Peng, Shanrun Wang, Lin Wen, Juhui Qiu et al. · 2026 · Bioengineering & Translational Medicine
  95. Cryopreservation of human cortical organoids using vitrification
    Kyle Stokes, Sandra P. Mojica-Perez, Samantha Jacobs, Joy Huang, Shivanshi Vaid, Yukun Yuan, Caroline Alayne Pearson, Daniel Montes, Andrew M. Tidball, Debora VanHeyningen et al. · 2026 · Frontiers in Molecular Neuroscience
  96. Morphogen‐Directed, High‐Throughput Development of hiPSC‐Derived Telencephalic Organoids for Comparative In Vitro Phenotyping
    Dosh Whye, Erika M. Norabuena, Wardiya Afshar Saber, Becca Lewis, Taryn J. Polanco, Delaney Wood, Mustafa Sahin, Elizabeth D. Buttermore · 2026 · Current Protocols
  97. Using Brain Organoids to Explore Human Neurobiology
    Hany E. S. Marei, Anwarul Hasan · 2026 · Cellular and Molecular Neurobiology
  98. Tutorial: interrogating biology using organoid technologies
    Jeroen M. Bugter, Simon T. Schafer, Roland Rad · 2026 · Nature Protocols
  99. Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells
    Haishuang Lin, Yue Wang, Hu DU, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin · 2026 · Advanced Science
  100. Human brain assembloids as a model of anaesthetic-induced neural dynamics in vitro
    Daniel Toker, Colin M. McCrimmon, Qing Cao, Anandita Pandey, Asia Guzman, Anjana Shriram, Andrew E. Hudson, Martin Max Monti, Ranmal Aloka Samarasinghe · 2026 · British Journal of Anaesthesia