A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells
Ang, Lay Teng, Tan, Antson Kiat Yee, Autio, Matias I., Goh, Su Hua, Choo, Siew Hua, Lee, Kian Leong, Tan, Jianmin, Pan, Bangfen +14 more·2018·Cell Reports
Cited by (228)
Items 101–200 of 228
- Microfluidic Techniques for Next‐Generation Organoid SystemsJing Gong, Minghui Li, Jiahui Kang, Zhiyuan Yin, Zhe Cha, Jun Yang, Haiwei Xu · 2022 · Advanced Materials Interfaces
- Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitmentSnabel, Rebecca R., Cofiño-Fabrés, Carla, Baltissen, Marijke, Schwach, Verena, Passier, Robert, Veenstra, Gert Jan C. · 2025 · Stem Cell Reports
- Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiationYan Fung Wong, Yatendra Kumar, Martin Proks, José Alejandro Romero Herrera, Michaela Rothová, Rita S. Monteiro, Sara Pozzi, Rachel E. Jennings, Neil A. Hanley, Wendy A. Bickmore et al. · 2023 · Nature Cell Biology
- Induced Pluripotent Stem Cells (Ipscs) Based Liver Organoid: the Benefits and ChallengesWahyunia Likhayati Septiana, Ariyani Noviantari, Radiana Dhewayani Antarianto · 2023 · Cellular Physiology and Biochemistry
- Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitorsFrankie Poon, Rangarajan Sambathkumar, Roman Korytnikov, Yasaman Aghazadeh, Amanda Oakie, Paraish S. Misra, Farida Sarangi, M. Cristina Nostro · 2024 · Nature Communications
- Genetic Diagnosis in Hereditary Hemochromatosis: Discovering and Understanding the Biological Relevance of VariantsFloor S Baas, Gautam Rishi, Dorine W. Swinkels, V. Nathan Subramaniam · 2021 · Clinical Chemistry
- Robust parameter design of human induced pluripotent stem cell differentiation protocols defines lineage-specific induction of anterior-posterior gut tube endodermal cellsRyota Yasui, Keisuke Sekine, Kiyoshi Yamaguchi, Yoichi Furukawa, Hideki Taniguchi · 2021 · Stem Cells
- Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like CellsMariia S. Bogacheva, Margarita A. Bystriakova, Yan‐Ru Lou · 2021 · Pharmaceuticals
- Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput ApplicationsMichael J. Iannotti, Ryan MacArthur, Richard C. Jones, Dingyin Tao, Ilyas Singeç, Sam Michael, James Inglese · 2019 · ACS Chemical Biology
- Opportunities for Antibody Discovery Using Human Pluripotent Stem Cells: Conservation of Oncofetal TargetsHeng Liang Tan, Andre B.H. Choo · 2019 · International Journal of Molecular Sciences
- Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived ModelJun Tsuchiya, Masato Miyoshi, Sei Kakinuma, Fukiko Kawai‐Kitahata, Akihide Kamiya, Taro Shimizu, Ayako Sato, Keiya Watakabe, Tomohiro Mochida, Kento Inada et al. · 2024 · Cellular and Molecular Gastroenterology and Hepatology
- Advances in liver engineering with cell, scaffold, and vascularizationChunyan Liu, Yulian Wang, Xuqian Zhou, Lei Dong · 2024 · EngMedicine
- FGF signaling mediates definitive endoderm formation by regulating epithelial-to-mesenchymal transition and cell proliferationShengbiao Li, Qingsong Huang, Jianwen Mao · 2020 · The International Journal of Developmental Biology
- Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochipsMathieu Danoy, Stéphane Poulain, Benedikt Scheidecker, Rachid Jellali, Yannick Tauran, Marjorie Leduc, Johanna Bruce, Françoise Gilard, Bertrand Gakière, Hiroshi Arakawa et al. · 2022 · Biochemical Engineering Journal
- Bile acid-FXR signaling facilitates the long-term maintenance of hepatic characteristics in human iPSC-derived organoidsTaro Shimizu, Masato Miyoshi, Sei Kakinuma, Jun Tsuchiya, Daisuke Yamane, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Kaho Yamada, Kotomi Shinozaki et al. · 2025 · Cell Reports
- An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtypeKathleen C. Keough, Parisha P. Shah, Ketrin Gjoni, Garrett T. Santini, Nadeera M. Wickramasinghe, Carolyn E. Dundes, Ashley M. Karnay, Angela C. Chen, Rachel E.A. Salomon, Patrick J. Walsh et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cellsChristiane Loerch, Leon-Phillip Szepanowski, Julian Reiss · 2024 · Frontiers in Cell and Developmental Biology
- Crosstalk via ICAM-1 enhances supportive phenotype of stellate cells and drives hepatocyte proliferation in iPSC-derived hepatic organoidsTomohiro Mochida, Masato Miyoshi, Sei Kakinuma, Taro Shimizu, Jun Tsuchiya, Keiya Watakabe, Kento Inada, Shun Kaneko, Fukiko Kawai‐Kitahata, Miyako Murakawa et al. · 2025 · Stem Cell Reports
- Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from Human Pluripotent Stem Cells in Two-Dimensional CultureKoki Yoshimoto, Koichiro Maki, Taiji ADACHI, Ken‐ichiro Kamei · 2023 · Tissue Engineering Part A
- Identification and Characterization of a 2,2-Dichloropropionic Acid (2,2-DCP) Degrading Alkalotorelant Bacterium Strain BHS1 Isolated from Blue Lake, TurkeyBatool Hazim Abdul Wahhab, Nurul Fatin Syamimi Khairul Anuar, Roswanira Abdul Wahab · 2020 · Journal of Tropical Life Science
- Calcitriol promotes the maturation of hepatocyte-like cells derived from human pluripotent stem cellsYuan Fang, Ning Wang, Yan Chen, Xinping Huang, Zhen Yang, Yingying Xu, Kai You, Jiaye Zhang, Guodong Wang, Yuanqi Zhuang et al. · 2021 · The Journal of Steroid Biochemistry and Molecular Biology
- Lineage reprogramming of human adipose mesenchymal stem cells to immune modulatory i-HepsSowmya Jahnavi, Vaishali Garg, Anoop Babu Vasandan, Swathi SundarRaj, Anujith Kumar, Jyothi Prasanna · 2022 · The International Journal of Biochemistry & Cell Biology
- PDGF Receptors and Signaling Are Required for 3D-Structure Formation and Differentiation of Human iPSC-Derived Hepatic SpheroidsSyusaku Tsuzuki, Tomoyuki Yamaguchi, Takashi Okumura, Toshiharu Kasai, Yasuharu Ueno, Hideki Taniguchi · 2023 · International Journal of Molecular Sciences
- Rat liver extracellular matrix and perfusion bioreactor culture promote human amnion epithelial cell differentiation towards hepatocyte-like cellsSara Campinoti, Bruna Almeida, Negin Goudarzi, Stefan Bencina, Fabio Grundland-Freile, Claire McQuitty, Dipa Natarajan, Isobel Jane Cox, Adrien D. Le Guennec, Vamakshi Khati et al. · 2023 · Journal of Tissue Engineering
- Efficient Differentiation of Human Pluripotent Stem Cells into Liver CellsKyle M. Loh, Amrita Palaria, Lay Teng Ang · 2019 · Journal of Visualized Experiments
- Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transitionQiuhong Li, Qingsong Huang · 2019 · PLoS ONE
- Nuclear Organization during Hepatogenesis in Zebrafish Requires Uhrf1Bhavani P. Madakashira, Chi Zhang, Filippo Macchi, Elena Magnani, Kirsten C. Sadler · 2021 · Genes
- HepG2-Based Designer Cells with Heat-Inducible Enhanced Liver FunctionsHiroyuki Kitano, Yoshinori Kawabe, Masamichi Kamihira · 2022 · Cells
- Influence of lyophilization primary drying time and temperature on porous silk scaffold fabrication for biomedical applicationsAlycia Abbott, Mattea E. Gravina, Mobin Vandadi, Nima Rahbar, Jeannine M. Coburn · 2022 · Journal of Biomedical Materials Research Part A
- Metabolically purified human stem cell-derived hepatocytes reveal distinct effects of Ebola and Lassa virusesJoseph B. Prescott, Kevin J. Liu, Angelika Lander, Nicole Min Qian Pek, Sawan Kumar Jha, Marcel Bokelmann, Manali Begur, Pang Wei Koh, Henry He Yang, Bing Lim et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Microfluidic fabricated cell-laden microgels aggregated into artificial liver microtissue to ameliorate drug-induced liver injuryFenfang Li, Tiantian Xue, Yanteng Xu, Haixia Wang, Enguo Ju, Mingqiang Li, Yu Tao · 2025 · Biomaterials
- Recapitulating the liver niche in vitroKiryu K. Yap, Geraldine M. Mitchell · 2022 · Advances in stem cells and their niches
- Applications and limitations of pluripotent stem cell-derived liver organoidsZhiwei Feng, Bingrui Zhou, Qizhi Shuai, Jianbing Mu, Jun Xie · 2025 · Chinese Medical Journal
- Induced hepatic stem cells are suitable for human hepatocyte productionYoshiki Nakashima, Chika Miyagi‐Shiohira, Issei Saitoh, Masami Watanabe, Masayuki Matsushita, Masayoshi Tsukahara, Hirofumi Noguchi · 2022 · iScience
- Trans-interaction of risk loci 6p24.1 and 10q11.21 is associated with endothelial damage in coronary artery diseaseKai Yi Tay, Kan Xing Wu, Florence WJ Chioh, Matias Ilmari Autio, Nicole Min Qian Pek, Balakrishnan Chakrapani Narmada, Sock Hwee Tan, Adrian Fatt-Hoe Low, Michelle Mulan Lian, Elaine Guo Yan Chew et al. · 2022 · Atherosclerosis
- Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fateWilliam Samuel Fagg, Naiyou Liu, Ulrich Braunschweig, Karen Larissa Pereira de Castro, Xiaoting Chen, Frederick S. Ditmars, Steven G. Widen, John Paul Donohue, Katalin Módis, William K. Russell et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Protocol for the generation of HLF+ HOXA+ human hematopoietic progenitor cells from pluripotent stem cellsSherry Li Zheng, Jonas L. Fowler, Julie Y. Chen, Christopher Li, Elaine Lin, Alana T. Nguyen, Angela C. Chen, George Q. Daley, Lay Teng Ang, Kyle M. Loh · 2025 · STAR Protocols
- Three-dimensional cell-based strategies for liver regenerationDan Guo, XI XIA, Jian Yang · 2024 · Biocell
- Chemically defined and growth factor-free system for highly efficient endoderm induction of human pluripotent stem cellsZhiju Zhao, Fanzhu Zeng, Yage Nie, Gang Lü, He Xu, He En, Shanshan Gu, Wai‐Yee Chan, Nan Cao, Jia Wang · 2024 · Stem Cell Reports
- ER stress reliever enhances functionalities of in vitro cultured hepatocytesJeong Seong Kim, Seon In Hwang, Jung Lim Ryu, Hee Su Hong, Ji-Min Lee, Sang Min Lee, Xiong Jie Jin, Choongseong Han, Jong‐Hoon Kim, Jaeseok Han et al. · 2020 · Stem Cell Research
- An Efficient Method for Directed Hepatocyte-Like Cell Induction from Human Embryonic Stem CellsQi Zhou, Xiaoling Xie, Zhiqian Zhong, Pingnan Sun, Xiaoling Zhou · 2021 · Journal of Visualized Experiments
- Homogeneous Differentiation of Functional Hepatocytes from Human Induced Pluripotent Stem CellsRong Li, Yang Zhao, Jeffrey J. Yourick, Robert L. Sprando, Xiugong Gao · 2022 · Methods in molecular biology
- Top‐Down Inhibition (TDi) and Baseline Activation (BLa): Controlling Signal Transduction When Endogenous Cytokines are Ruining Your DifferentiationJames O.S. Hackland · 2019 · Current Protocols in Stem Cell Biology
- Copy Number Variation at 16p11.2 Imparts Transcriptional Alterations in Neural Development in an hiPSC-derived Model of CorticogenesisJulien George Roth, Kristin L. Muench, Aditya Asokan, Victoria M Mallett, Hui Gai, Yogendra Verma, Stephen G. Weber, Carol A. Charlton, Jonas L. Fowler, Kyle M. Loh et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Platform-Agnostic CellNet (PACNet) enables cross-study meta-analysis of cell fate engineering protocolsEmily K.W. Lo, Jeremy J. Velazquez, Da Peng, Chulan Kwon, Mo R. Ebrahimkhani, Patrick Cahan · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3Jennifer M. Umhoefer, Maya M. Arce, Sean Whalen, Rama Dajani, Laine Goudy, Sivakanthan Kasinathan, Julia A. Belk, Wenxi Zhang, Royce Zhou, Sanjana Subramanya et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- A review of current state-of-the-art materiobiology and technological approaches for liver tissue engineeringShadil Ibrahim Wani, Tanveer Ahmad Mir, Makoto M. Nakamura, Tomoshi Tsuchiya, Alaa Alzhrani, Shintaroh Iwanaga, Kenichi Arai, Eman A. Alshehri, Talal Shamma, Dalia Abdullah Obeid et al. · 2024 · Bioprinting
- A microfluidic platform for anterior-posterior human endoderm patterning via countervailing morphogen gradients in vitroLeeya Engel, Kevin J. Liu, Kiara W. Cui, Eva L. de la Serna, Vipul T. Vachharajani, Carolyn E. Dundes, Sherry Li Zheng, Manali Begur, Kyle M. Loh, Lay Teng Ang et al. · 2025 · iScience
- Effects of PDMS culture on stem cell differentiation towards definitive endoderm and hepatocytesChristopher T. Clark, Yao Wang, Devin C. Johnson · 2025 · Acta Biomaterialia
- Biochemical and Biophysical Properties of Extracellular Matrix Nanofibers Modulate iPSC ‐Derived Human Hepatocyte MaturationYuan Yang, Liszt Y. C. Madruga, Kristen Y. Cotton, Matt J. Kipper, Salman R. Khetani · 2025 · Journal of Biomedical Materials Research Part A
- Application of stem cells in the precise diagnosis and treatment of liver diseasesYuan-Xin Wang, Ya-Nian Ren, Shan-Shan Zhang, Shan Sun, Ming-Yi Xu, Teng Wei, Lei-Sheng Zhang · 2025 · World Journal of Gastroenterology
- Melatonin pretreatment can improve the therapeutic effect of adipose-derived stem cells on CCl4-induced liver fibrosisZiqiang Zhang, Yingying Sun, Haojie Wang, Yuxiang Yang, Ruiqi Dong, Yaolu Xu, Mengyu Zhang, Qiongxia Lv, Xiaoguang Chen, Yumei Liu · 2023 · Toxin Reviews
- Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cellsSaeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Hidenori Nonaka, Masashi Toyoda, Akihide Kamiya, Tohru Kiyono, Tohru Kimura, Mureo Kasahara et al. · 2023 · Progress in molecular biology and translational science
- Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseasesYisu Song, Zhengyang Lu, Wenzhi Shu, Ze Xiang, Zhengxin Wang, Xuyong Wei, Xiao Xu · 2023 · Cell Insight
- Integrative Protocol for Generation of iPSC-Derived 3D Human Hepatic OrganoidsJorge Hidalgo-Álvarez, Tatiana L. Fonseca, Federico Salas-Lucia, Antonio Carlos Bianco · 2024 · Journal of Visualized Experiments
- Generation and characterization of induced pluripotent stem cells of small apesYusuke Hamazaki, Hiroto Akuta, Hikaru Suzuki, Hideyuki Tanabe, Kenji Ichiyanagi, Takuya Imamura, Masanori Imamura · 2025 · Frontiers in Cell and Developmental Biology
- A clinically defined and xeno-free hydrogel system for regenerative medicineJohn Ong, George M. Gibbons, Yee Siang Lim, Lei Zhou, Junzhe Zhao, Alexander W. Justin, Federico Cammarata, Ravisankar Rajarethinam, Colleen A. Limegrover, Sanjay Sinha et al. · 2026 · Materials Futures
- Liver stem cellsDagmara Szkolnicka, David C. Hay · 2020 · Elsevier eBooks
- Doxycycline Significantly Enhances Induction of iPSCs to Endoderm by Enhancing survival via AKT PhosphorylationCristina Esteva‐Font, Tao Su, Caitlin Peaslee, Caroline C. Duwaerts, Ke Liu, Marisa Wong Medina, Jacquelyn J. Maher, Aras N. Mattis · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Expandable, Functional Hepatocytes Derived from Primary Cells Enable Liver TherapeuticsSunil K. Mallanna, Soujanya S. Karanth, Joseph E. Marturano, Abhijith Kundadka Kudva, Marcus Lehmann, Julie K. Morse, Morgan Jamiel, Timothy J. Norman, Christopher Wilson, Fabiola Munarin et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- TBX3 advances the developmental chromatin landscape toward the hepatic fateStephan, Tabea L., Cullum, Rebecca, Drissler, Sibyl, Thomas, Ashleigh, Fuglerud, Bettina M., Clement-Ranney, Makenna, Lotto, Jeremy, Krentz, Nicole A.J., Duncan, Stephen A., Hoodless, Pamela A. · 2025 · Developmental Cell
- Lessons from the Embryo: an Unrejected Transplant and a Benign TumorAlaleh Rezalotfi, Angelos Varotsos Vrynas, Maryam Dehghanian, Nima Rezaei · 2020 · Stem Cell Reviews and Reports
- Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolismWesley H. Godfrey, Judy J. Lee, Shruthi Shanmukha, Kaho Cho, Xiaojing Deng, Chandrashekar R. Ambati, Vasanta Putluri, Abu Hena Mostafa Kamal, Paul M Kim, Nagireddy Putluri et al. · 2025 · eLife
- Oxidative stress and GPX2 control pancreatic vs. non-pancreatic cell fate in human endodermJoanna Szpotkowska, Wojciech J. Szlachcic, Katarzyna Błaszczyk, Maja Baginska, Magdalena Socha, Malgorzata Borowiak · 2026 · Nature Communications
- Role of Hepatocyte Nuclear Factor 4α in Regulating Hepatic Differentiation and the Inflammatory Response in HCCWen Li Zhou, Zhan Wang, Mingyong Miao, Yuan Sheng Zang · 2019 · journal of nutritional oncology
- Long noncoding RNA VENTHEART is required for cardiomyocyte specification and functionAlbert Dashi, Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu, Bangfen Pan, Autio Matias Ilmari, Zenia Tiang, Robin J. G. Hartman, Justus Stenzig, Heming Wei, Chen Gao Bin et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Quantitative analysis and genome-scale modeling of human CD4 + T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathwaysPartho Sen, Syed Bilal Ahmad Andrabi, Tanja Buchacher, Mohd Moin Khan, Ubaid Ullah, Tuomas Lindeman, Marina Alves Amaral, Victoria Hinkkanen, Esko Kemppainen, Alex M. Dickens et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Comparative chromatin accessibility upon BDNF-induced neuronal activity delineates neuronal regulatory elementsIgnacio L. Ibarra, Vikram Singh Ratnu, Lucia Gordillo, In‐Young Hwang, Luca Mariani, Kathryn Weinand, Henrik M. Hammarén, Martha L. Bulyk, Mikhail M. Savitski, Judith B. Zaugg et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A nuclear receptor facilitates differentiation of human PSCs into more mature hepatocytesHaiting Ma, Esmée de Zwaan, Yang Eric Guo, Paloma Cejas, Prathapan Thiru, Martijn van de Bunt, Jacob Fuglsbjerg Jeppesen, Sudeepa Syamala, Alessandra Dall’Agnese, Brian J. Abraham et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Expansion of Ventral Foregut Primes the Enhancer Landscape for Organ Specific DifferentiationYan Fung Wong, Yatendra Kumar, Martin Proks, José Alejandro Romero Herrera, Michaela Rothová, Rita S. Monteiro, Sara Pozzi, Rachel E. Jennings, Neil A. Hanley, Wendy A. Bickmore et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturationOgechi Ogoke, Daniel Guiggey, Alexander Chiang, Sarah Thompson, Tram Hoang Anh Nguyen, Daniel Berke, Cortney Ott, Allison J. Kalinousky, Claire Shamul, Peter Chen et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activationMichael Rade, Sebastian Böhlen, Vanessa Neuhaus, Dennis Löffler, Conny Blumert, Ulrike Koehl, Susann Dehmel, Katherina Sewald, Kristin Reiche · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Highly enhanced transgene integration in human pluripotent stem cells by serine integrase BxbIMatias Ilmari Autio, Arnaud Perrin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Glycan-Mediated Mechanosensing Regulates Megakaryocyte-Biased Hematopoietic Stem Cell SubsetsAlejandro Roisman, Leonardo Rivadeneyra, Lindsey R. Conroy, Melissa M. Lee‐Sundlov, Natalia Weich, Simon H. Glabere, Shikan Zheng, Katelyn E. Rosenbalm, Mark Zogg, George Steinhardt et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturationChristopher Lee, Farah Tasnim, Xiaozhong Huang, Raman Sethi, Yaqi Song, Tatsuya Kozaki, Sebastiaan De Schepper, Nicholas Ang, Ivy Low, You Yi Hwang et al. · 2025 · eLife
- Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturationChristopher Lee, Farah Tasnim, Xiaozhong Huang, Raman Sethi, Yaqi Song, Tatsuya Kozaki, Sebastiaan De Schepper, Nicholas Ang, Ivy Low, You Yi Hwang et al. · 2025 · eLife
- Defective HNF1A hinders GLI3 processing favoring duodenal versus pancreatic fate, thus leading to intestinal elongation in vivoLucas Unger, Ulrik Larsen, T. A. Legøy, Md Kaykobad Hossain, J.H. Gudmestad, Amanda Friestad, Shayla Sharmine, P. Njølstad, H. Ræder, P. Herrera et al. · 2026 · Genes & Development
- Engenharia tecidual hepática utilizando células tronco pluripotentes induzidasErnesto da Silveira Goulart Guimarães · 2019
- Pluripotent Stem Cells and ReprogrammingJames A. Heslop, Stephen A. Duncan · 2020
- Heat treatment functionalizes hepatocyte-like cells derived from human embryonic stem cellsSatoshi Imamura, Koki Yoshimoto, Shiho Terada, Ken‐ichiro Kamei · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Hepatocytes and Bile FormationSanjeev Kumar Gupta, David Q.‐H. Wang · 2019 · Encyclopedia of Gastroenterology
- Modified CRISPR/Cas9 mediated generation of two MKK7 knockout human embryonic stem cell linesClive Sims, Matias Ilmari Autio, Adriana Buskin · 2021 · Stem Cell Research
- Generation of vascularized 3-dimensional (3D) kidney organoids from human pluripotent stem cellsJian Hui Low · 2020
- Differentiation of Stem Cells into Hepatocyte Lineage: In Vitro Cell Culture, In Vivo Transplantation in Animal ModelsMunther Alomari · 2021 · Stem cell biology and regenerative medicine
- Melatonin pretreatment can improve the therapeutic effect of Adipose-derived Stem Cells on CCl4-induced liver fibrosisZiqiang Zhang, Yingying Sun, Haojie Wang, Yuxiang Yang, Ruiqi Dong, Yaolu Xu, Mengyu Zhang, Qiongxia Lv, Xiaoguang Chen, Yumei Liu · 2021 · Research Square
- A Microfluidic Platform for Anterior-Posterior Human Endoderm Patterning via Countervailing Morphogen Gradients in vitroKiara W. Cui, Leeya Engel, Kevin J. Liu, Vipul T. Vachharajani, Carolyn E. Dundes, Sherry Li Zheng, Manali Begur, Kyle M. Loh, Lay Teng Ang, Alexander R. Dunn · 2022 · SSRN Electronic Journal
- Pioneer transcription factors coordinate active and repressive gene expression states to regulate cell fateSatoshi Matsui, Marissa Granitto, Morgan Buckley, Joseph R Shiley, William J. Zacharias, Christopher N. Mayhew, Hee‐Woong Lim, Makiko Iwafuchi · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- LiverGary C. Kanel · 2023 · Elsevier eBooks
- Differentiation potential of human amniotic fluid-derived mesenchymal stem cells into hepatocyte-like cellsNapatsaree Nuttapasita, Sirinda Aungsuchawan, Suteera Narakornsak · 2024 · ScienceAsia
- A Knowledge-driven Deep Learning Framework for Organoid Morphological Segmentation and CharacterisationYiming Qin, Jiajia Li, Heng Yin, Dezhi Wu, Xuejiao Liu, Tobias Plötz, Alexander Vincent Hopp, Nicholas A. Kurniawan, Mathias Winkel, Philipp H. P. Harbach et al. · 2024 · Research Square
- Generation of Human Liver Organoids (HLOs) on Pillar/Perfusion Platform via Microarray 3D Bioprinting and Study of Genetic Diversity in DILISunil Shrestha · 2024
- Potential role of Sigma-1 receptor inhibition and ER stress-related pathways in upregulating definitive endoderm markers in human embryonic stem cellsElmira Rezaei Zonooz, Zahra Ghezelayagh, Azadeh Moradmand, Hamid Reza Aghayan, Faezeh Shekari, Yaser Tahamtani · 2025 · Experimental Cell Research
- Coronary Artery Disease Risk Variant rs6903956 Links to Endothelial Dysfunction via PHACTR1 RegulationKai Yi Tay, Hannah Su-Ann Wee, Nhi Le Uyen Nguyen, Matias Ilmari Autio, Vanessa Kristina Wazny, Khang Leng Lee, Darwin Tay, Yuting Wang, Xu Gao, Chew‐Kiat Heng et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Large-Scale Organoid Culture for High Throughput Drug ScreeningShraddha Gautam, Atul Kumar Singh, Sachin Kadam · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
- MAPK/ERK signaling blocks ectopic H3K9me3 heterochromatin formation to confer mesoderm and endoderm developmental competenceSatoshi Matsui, Marissa Granitto, Samuel Sampson, Gerardo Gabriel Mirizio, Ryo Maeda, Makoto Tachibana, Christopher Ahn, Hee‐Woong Lim, Makiko Iwafuchi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturationChristopher Zhe Wei Lee, Farah Tasnim, Xiaozhong Huang, Raman Sethi, Yaqi Song, Tatsuya Kozaki, Sebastiaan De Schepper, Nicholas Ang, Ivy Low, You Yi Hwang et al. · 2026 · eLife
- Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate MetabolismTimo Keskinen, Sami Jalil, Irem Ilgın Gümüşoğlu, Juhana Juutila, Nadim Kestilä, Emilia Kuuluvainen, Ville Hietakangas, Diego Balboa, Kirmo Wartiovaara, Mervi E. Hyvönen · 2025 · Journal of Inherited Metabolic Disease
- Generation and transcriptome profiling of bonobo induced pluripotent stem cells using stealth RNA vectors: a tripartite comparative study with humans and chimpanzeesYusuke Hamazaki, Hiroto Akuta, Hikaru Suzuki, Hideyuki Tanabe, Tsubasa Suzuki, Kouki Inoue, Kenji Ichiyanagi, Takuya Imamura, Masanori Imamura · 2025 · BMC Genomics
- Additional file 6 of An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtypeParisha P. Shah, Kathleen C. Keough, Ketrin Gjoni, Garrett T. Santini, Abdill, Richard J., Nadeera M. Wickramasinghe, Carolyn E. Dundes, Ashley M. Karnay, Angela C. Chen, Rachel E.A. Salomon et al. · 2024 · Figshare
- Additional file 6 of Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic optionsMargaretha A. Skowron, Mara Kotthoff, Felix Bremmer, K. Ruhnke, Fatma Parmaksiz, Annika Richter, Stefan Küffer, Kirsten Reuter‐Jessen, Stella Pauls, Anja Stefanski et al. · 2024 · Figshare