Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Jeong, Mira, Park, Hyun Jung, Celik, Hamza, Ostrander, Elizabeth L., Reyes, Jaime M., Guzman, Anna, Rodriguez, Benjamin, Lei, Yong +6 more·2018·Cell Reports

Cited by (243)

Items 201–243 of 243

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  2. [Effect of clonal hematopoiesis in remission on hematopoiesis recovery in patients with NPM1 mutated acute myeloid leukemia after chemotherapy].
    L L Wang, S N Chen · 2023 · PubMed Central
  3. ВЛИЯНИЕ КЛОНАЛЬНОГО ГЕМАТОПОЭЗА С НЕОПРЕДЕЛЕННЫМ ПОТЕНЦИАЛОМ (CHIP) НА РАЗВИТИЕ АТЕРОСКЛЕРОЗА
    Makhabbat S. Bekbossynova, S.A. Andosova, A. Rysbekova, Daniyarova Gulnur D. · 2024 · Ġylym men densaulyķ saķtau.
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  5. Additional file 2 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  6. Additional file 21 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  7. Additional file 1 of DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells
    Li, Weijing, Liu, Shuguang, Wang, Chanjuan, Cui, Lei, Xiaoxi Zhao, Liu, Wei, Ruidong Zhang, Li, Zhigang · 2023 · Figshare
  8. Additional file 4 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  9. Additional file 3 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  10. Additional file 18 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  11. Additional file 13 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  12. Additional file 7 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  13. Additional file 12 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  14. Additional file 17 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  15. Additional file 6 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  16. Additional file 11 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  17. Additional file 5 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  18. Additional file 1 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  19. Additional file 16 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Jianfei Fu · 2021 · Figshare
  20. Additional file 15 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  21. Additional file 9 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  22. Additional file 19 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  23. Additional file 14 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  24. Additional file 10 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Jie Zhou, Guo, Cheng, Wu, Hao, Bing Li, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  25. Additional file 1 of Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation
    Olivia Cypris, Julia Franzen, Joana Frobel, Philipp Glück, Kuo, Chao-Chung, Stephani Schmitz, Selina Nüchtern, Martin Zenke, Wolfgang Wagner · 2022 · Figshare
  26. Additional file 20 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Fu, Jian-Fei · 2021 · Figshare
  27. Additional file 8 of Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
    Zhou, Jie, Guo, Cheng, Wu, Hao, Li, Bing, Zhou, Li-Li, Liang, Ai-Bin, Jianfei Fu · 2021 · Figshare
  28. DNA Methyltransferases in Human Biology and Diseases: Epigenetic Regulator to Therapeutic Targets
    Ashutosh Kumar Arya, Priyanka Singh, V K Sharma · 2026 · Springer eBooks
  29. Retrotransposons Promote Dnmt3a -Mutant Clonal Hematopoiesis Through Aging-Related Stromal Inflammation
    Qiongdi Zhang, Wenhuo Hu, Joshua Theriot, Michael Lee, Sabrina Rinaldi, Yoon Jung Kim, Donghong Cai, Kathryn E. Dickerson, Jennifer J. Trowbridge, Nan Yan et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Etude du rôle du récepteur à la vitamine D (VDR) dans l'hématopoïèse normale et dans les Leucémies Aiguës Myéloïde -lien avec la voie des Bone Morphogenetic Protein
    Florence Zylbersztejn · 2018 · theses.fr (ABES)
  31. Critical and different roles of DNA methylation in male germ cell development
    Mathilde Dura · 2021
  32. How Somatic Mutations cause Aging without Causing Aging
    Alexander Martin Wolf · 2026 · SSRN Electronic Journal
  33. Caractérisation de nouvelles dépendances oncogéniques dans les hémopathies myéloïdes
    Blandine Roux · 2022
  34. Caractérisation des mécanismes prédisposant aux néoplasmes myéloprolifératifs et aux hémopathies malignes
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  35. Clonal Metamorphosis: Deconstructing MPN Evolution with Single-Cell and Spatial Multi-Omics
    Muhammad Shahid Iqbal, Abdullah K. Alahmari, Mohd Faiyaz Khan, Sadaf Farooqui, Muhammad Zahid Iqbal, Salah-Ud-Din Khan, Nazia Khan, Vidya Devanathadesikan Seshadri, Amr Ali Mohamed Abdelgawwad El‐Sehrawy · 2026 · Clinical and Experimental Medicine
  36. Glycosylation orchestrates megakaryocytic fate of hematopoietic stem cells via Wnt-MUC13 signaling
    Alejandro Roisman, Leonardo Rivadeneyra, Lindsey R. Conroy, Natalia Weich, Agata Steenackers, Melissa M. Lee‐Sundlov, Simon H. Glabere, Shikan Zheng, Katelyn E. Rosenbalm, Mark Zogg et al. · 2026 · Nature Communications
  37. Tet2 deficiency drives age-related heterogeneous progression of myeloid neoplasms through epigenetic-immune microenvironment imbalance
    Yanxi Chen, Li Yu, Rui Yang, Pengjie Chen, Wen Zeng, Zihan Li, Yanting Wang, 许勇钢, Xiupeng Yang · 2026 · Journal of Translational Medicine
  38. Clonal hematopoiesis-associated DNMT3A mutations derepress bivalent Polycomb target genes and enhance macrophage migration
    Yuri Lee, Philip K. Farahat, Jennifer Nguyen, Yoshiko Takahashi, Jung-Yeon Lim, Xin Huang, Camille Brzechffa, Marie E. S. Wheeler, Hye-Ju Yang, Jihye Lee et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  39. The Runx1-Gata2 axis: epigenetic architecture of lineage fate
    Sumit Mallick, Anirban Chakraborty · 2026 · Molecular Biology Reports
  40. Silent, but not innocent: the emerging role of clonal hematopoiesis in predicting therapy-related myeloid neoplasms
    Şerife Emre Ünsal · 2026 · Frontiers in Oncology
  41. Single-cell CRISPR screen maps epigenetic regulators of lineage specification and malignancies in human HSPCs
    Shiru Yuan, Shangda Yang, Yaojin Huang, Baowei Ma, Qian Wu, Xinghui Zhang, Tong Yin, Lianting Chen, Baixuan Zhang, Guohuan Sun et al. · 2026 · Cell stem cell
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  43. 3171 – ABERRANT OXIDATIVE METABOLISM SELECTS FOR TET2-DEFICIENT HEMATOPOIETIC STEM AND PROGENITOR CELLS
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