Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair

Finn, Johanna, Sottoriva, Kilian, Pajcini, Kostandin V., Kitajewski, Jan K., Chen, Chang, Zhang, Wei, Malik, Asrar B., Liu, Yuru·2019·Cell Reports

Cited by (133)

Items 101–133 of 133

  1. Alveolar epithelial progenitor cells drive lung regeneration via dynamic changes in chromatin topology modulated by lineage-specific Nkx2-1 activity
    Andrea Tóth, Paranthaman Senthamarai Kannan, John M. Snowball, Matthew J. Kofron, Joseph A. Wayman, James P. Bridges, Emily R. Miraldi, Daniel T. Swarr, William J. Zacharias · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  2. Staged Construction of Pluripotent Stem Cell Lung Models for Assessing Respiratory Toxicity of Environmental Pollutants
    Shuxian Zhang, Renjun Yang, Nuoya Yin, Francesco Faiola · 2025 · Environment & Health
  3. Modulation of an aberrant basal cell program in human alveolar epithelial spheroids and lung slices
    Yong Li, Jack H. Wellmerling, Lorena Rosas, Patrick A. Link, Daniela Chow, Joshua Alvarez, Kyoung Moo Choi, Ana Maria Diaz Espinosa, Rachel M. Gilbert, N. Goplen et al. · 2025 · Respiratory Research
  4. Inhalable nanoparticles restore airway-alveolar homeostasis by inhibiting bronchiolarization and epithelial-mesenchymal transition for idiopathic pulmonary fibrosis therapy
    Xue-Na Li, Xi-Xi Ma, Ya-Ping Lin, Bin Huang, Jin-You Piao, Hong-Tai Xu, Lei Xing, Jee-Heon Jeong, Xian Wu Cheng, Yanqiu Xu et al. · 2026 · Chinese Chemical Letters
  5. Mechanisms of lung regeneration and repair
    Ashutosh Tripathy, Gamze Cigdem Gelincik, Ana Pardo–Saganta · 2026 · Current Opinion in Genetics & Development
  6. Crucial role played by CK8+ cells in mediating alveolar injury remodeling for patients with COVID-19
    Yufeng Li, Hengrui Hu, Jia Liu, Longda Ma, Xi Wang, Liang Liu, Qian Liu, Liang Ren, Jiang Li, Fēi Dèng et al. · 2024 · Virologica Sinica
  7. Fusu mixture alleviates inflammatory reactions in lipopolysaccharide-induced acute respiratory distress syndrome mice via regulation of surfactant-associated protein C, aquaporin 5, and Notch1
    Song Zhang, Yan Yue, Jing Liu, Lijia Zhi, Li Zhang, Kaichen Zhang, Peng Ding, Peiyang Gao, Kunlan Long · 2023 · Journal of Thoracic Disease
  8. Retention of DLK1 in the endoplasmic reticulum identifies roles for EGF ‐like‐domain‐specific O‐glycans in the secretory pathway
    Yuko Tashima, Yohei Tsukamoto, Natsumi Tsukamoto, Yuji Kondo, Ehsan Uddin, Wakako Furukawa, Shiori Go, Hiromu Arakawa, Hiroyuki Kaji, Hideyuki Takeuchi et al. · 2025 · FEBS Journal
  9. Mechanistic insights into intestinal stem cell disruption during infection
    Naomi Chege, Constance A. M. Finney · 2025 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  10. Cell-based treatments of lung diseases: overview and outlook
    Anne M. van der Does, Laura von Schledorn, Ruth Olmer · 2025 · Advanced Drug Delivery Reviews
  11. Delta-like 1 homologue (DLK1) predicts clinical outcomes in patients with hepatocellular carcinoma
    Kuan-Fu Huang, Tian‐Huei Chu, Kuo‐Chin Chang, Cheng-Kun Wu, Ming-Chao Tsai, Chao‐Cheng Huang, Hu Tsung-Hui, Ming Hong Tai · 2026 · Journal of the Formosan Medical Association
  12. Advances in understanding mitophagy's role in lung injury
    Wenyu Du, Youjing Yang, Tao Zhang, Junyu Jiang, Dingyuan Du, Guangbin Huang, Shasha Tao · 2026 · Chinese Journal of Traumatology
  13. The Gut–Lung Microbiome Axis in Alveolar Stem Cell Regeneration and Lung Repair
    Aotong Liu, Di Ran, Zekun Shen, Muhamed Rojba, Jilei Zhang · 2026 · Microorganisms
  14. Decoding lung complexity: single-cell sequencing in lung diseases, regeneration, and drug discovery
    Peng Wang, Nan-yan Tang · 2024 · Frontiers in Drug Discovery
  15. Reconstitution of Alveolar Regeneration via novel DATPs by Inflammatory Niches
    Jinwook Choi, Jong-Eun Park, Georgia Tsagkogeorga, Motoko Yanagita, Bon‐Kyoung Koo, Namshik Han, Joo‐Hyeon Lee · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Investigation of the Protective Effects of Mesenchymal Stem Cell-Derived Exosomes on Hyperoxia-Induced Type II Alveolar Epithelial Cell Injury Based on Ferroptosis and Autophagy
    Guoyue Liu, Guiyang Jia, Yingcong Ren, Qianxia Huang, Cunzhi Yin, Xuan Xiao, Hang Wu, Miao Chen · 2024 · Research Square
  17. MODELING VERTEBRATE ADULT STEM CELLS AND THEIR PROGENY
    Yorick Post · 2020
  18. Type I Cells
    Alessandra Castaldi, William Pinson-Rose, Alexa Allen, Zea Borok · 2021 · Elsevier eBooks
  19. Brahma-related gene 1 regulates the proliferation of alveolar type II epithelial cells via the JAK1/2-PI3K/AKT signaling pathway
    Maozhu Xu, Huijun Qiu, Lingyin Ruan, Linghuan Zhang, Lili Yang, Zhou Fu, Wenjing Zou · 2022 · Research Square
  20. Hamsters are a model for post-COVID-19 alveolar regeneration mechanisms: an opportunity to understand post-acute sequelae of SARS-CoV-2
    Laura Heydemann, Małgorzata Ciurkiewicz, Georg Beythien, Kathrin Becker, Klaus Schughart, Stephanie Stanelle‐Bertram, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Reanalysis of Single-Cell RNA-Sequencing Data in Patients with COVID-19: Insights and Limitations
    Chi F. Hung, Sina A. Gharib · 2023 · American Journal of Respiratory Cell and Molecular Biology
  22. Pulmonary Emphysema Reduced Alveolar Re-Epithelialization
    N. V. V. S.Vinayak Lingolu, Deena Kumari Mutyala, Sree Lakshmi Nayudu, Mr. Balaji B. V. B · 2024 · International Journal of Research Publication and Reviews
  23. Retention of DLK1 in the endoplasmic reticulum identifies roles for EGF domain-specific O-glycans in the secretory pathway
    Yuko Tashima, Yohei Tsukamoto, Natsumi Tsukamoto, Yuji Kondo, Ehsan Uddin, Wakako Furukawa, Shiori Go, Hideyuki Takeuchi, Tetsuya Okajima · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Clustering Single-Cell RNA-Seq Data with Low-Rank Matrix Factorization and Local Graph Regularization
    Yue Yu, Wei Zhang, Xiaoying Zheng, Juan Shen, Yuanyuan Li · 2025 · Interdisciplinary Sciences Computational Life Sciences
  25. Age-dependent immune responses and resident cell dynamics in young mice following pneumonia
    Sylvia N. Michki, Javier Vasconcelos Perez, Dharma A. Varapula, Aaron J. Thomas, Tiffaney L. Vincent, Benjamin David Singer, Jarod A. Zepp, Sharon A. McGrath‐Morrow · 2025 · iScience
  26. Notch mediates non-regenerative alveolar repair after staphylococcal lung injury
    Sarah K. Moore, Stephanie Tang, Deebly Chavez, Sayahi Suthakaran, Chaya Sussman, Jimmy Zhang, Jaime L. Hook · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Novel netrin-1–Unc5b–Klf4 axis balances AT2 survival in experimental bronchopulmonary dysplasia
    Oleksiy Klymenko, Jasmine Mohr, Soula Danopoulos, Ivana Mižik, Celien Kuiper-Makris, Stephanie Stephan, Mohammad A Mahjoub, Cristina M. Alvira, Daniela Rheindorf, Thomas Imhof et al. · 2026 · American Journal of Respiratory Cell and Molecular Biology
  28. Rôle des FGFs endocrines et leurs récepteurs au cours de la fibrose pulmonaire idiopathique
    Mada Ghanem · 2023 · theses.fr (ABES)
  29. SDPR – STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
    Jie Wang, Xuepei Lei, Yiying Huang, 汤家铭, Guiying Shi, Hang Li, Lin Bai · 2026 · Animal Models and Experimental Medicine
  30. A double-edged sword: iron regulation in alveolar lung epithelial repair
    Ugonna Mbaekwe, Sarah Kenny, Suzanne M. Cloonan, Corrine R. Kliment · 2026 · JCI Insight
  31. Large-scale proteome profiling identifies circulating biomarkers for disease activity and organ involvement in ANCA-associated vasculitides
    Erik Hellbacher, Ann Knight, Peter Hemmingsson, Anna Juto, Iva Gunnarsson, Annette N. Bruchfeld, Maria Weiner, Annika Söderbergh, Sophie Ohlsson, Rille Pullerits et al. · 2026 · Frontiers in Immunology
  32. Single-cell lineage tracing in tumor organoids identifies expansion states depicting the origin and progression of lung adenocarcinoma
    Wutao Chen, Peng Li, Hejian Zhang, Yumeng Sheng, Guoliang Yang, Jing Hu, Bin Yu · 2026 · Frontiers in Immunology
  33. Acute lung injury: an integrated view of molecular drivers, immune dysregulation, and emerging therapeutic strategies
    Aihua Wang, Haizhao Liu, 尹承芬, Yawen Song, Yue Jin, Lei Xu, Siwei Wang, Jiaxin Li, Xiping Guo, Yongli Ma et al. · 2026 · Frontiers in Immunology