Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
Lukey, Michael J., Cluntun, Ahmad A., Katt, William P., Lin, Miao-chong J., Druso, Joseph E., Ramachandran, Sekar, Erickson, Jon W., Le, Henry H. +4 more·2019·Cell Reports
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Items 101–105 of 105
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- Dysregulated PIKfyve-dependent inhibition of ClC-7 causes ammonium-dependent endolysosomal vacuolization and autophagic flux impairment: Rescue by glutaminase inhibitionJunsuke Uwada, Hitomi Nakazawa, Takashi Yazawa, Ikunobu Muramatsu, Takayoshi Masuoka · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- BindingDB Entry 50014276: Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50011564: Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.BindingDB · 2022 · UC San Diego