Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses

de Witte, Chris Jenske, Espejo Valle-Inclan, Jose, Hami, Nizar, Lõhmussaar, Kadi, Kopper, Oded, Vreuls, Celien Philomena Henrieke, Jonges, Geertruida Nellie, van Diest, Paul +8 more·2020·Cell Reports

Cited by (307)

Items 201–300 of 307

  1. Three-dimensional models: from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
    Sayumi Tahara, Sydney Rentsch, Fernanda Costas Casal de Faria, Patricia Sarchet, Roma Karna, Raphael E. Pollock, Federica Calore · 2024 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  2. The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐ x L or Mcl‐1 in ovarian cancer
    Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Émilie Brotin, Mélanie Briand, Énora Dolivet, Laurent Poulain et al. · 2025 · Molecular Oncology
  3. Advances in In Vitro Modeling of Cancer‐Stromal Interactions: From Fundamental Insights to Translational Applications
    Zhuoran Wu, Bingyi Zeng, Dong Hua Seah, Ian Zi Rui Ng, Rockie Haiyao Ding, Tianyi Zhang, Madhumathi Kalaichelvan, Ruochii You, Eliza Li Shan Fong · 2025 · Advanced Materials
  4. Toward Proteomic-Based Prediction of Ex Vivo Platinum Sensitivity in Ovarian Cancer Ascitic Cellular Aggregates: A Pilot Study
    Jack Scanlan, Parul Mittal, Noor A. Lokman, Martin Klaus Oehler, Peter Hoffmann, Manuela Klingler‐Hoffmann · 2025 · Journal of Proteome Research
  5. Culturally responsive strategies and practical considerations for live tissue studies in Māori participant cohorts
    Helena Abolins-Thompson, Kimiora L. Henare, Bridget Simonson, Mark D. Chaffin, Patrick T. Ellinor, Claire Henry, Mairarangi Haimona, Jake Aitken, Taku Parai, Bianca Elkington et al. · 2024 · Frontiers in Research Metrics and Analytics
  6. Establishing predictive machine learning models for drug responses in patient derived cell culture
    Abbi Abdel‐Rehim, Oghenejokpeme I. Orhobor, Gareth Griffiths, Larisa Soldatova, Ross D. King · 2025 · npj Precision Oncology
  7. Organoids and epithelial ovarian cancer ‑ a future tool for personalized treatment decisions?
    Yagmur Sisman, Tine Henrichsen Schnack, Estrid Vilma Solyom Høgdall, Claus Kim Høgdall · 2021 · Molecular and Clinical Oncology
  8. Les organoïdes derives de tumeurs (ou tumoroïdes), des outils de choix pour la medecine de precision en oncologie
    Marion Perréard, Romane Florent, Lucie Thorel, Audrey Vincent, Louis‐Bastien Weiswald, Laurent Poulain · 2022 · médecine/sciences
  9. AAV for ovarian cancer gene therapy
    Hee Chan Yoo, Sang-Kil Lee, Joong Yull Park, Eun‐Ju Lee · 2025 · Cancer Gene Therapy
  10. CT radiomic stratification signature to optimize clinical decisions for ovarian cancer patients receiving neoadjuvant chemotherapy and the underlying biological basis: a multicenter retrospective study
    Shimin Zhang, Xinyue Li, Siyang Zhang, Meiyao Li, Jiarui Wang, Jiage Zhang, Yutong Liu, Zhuonan Liu, Guan Wang, Yi Zhang et al. · 2025 · Journal of Translational Medicine
  11. Microfluidic single-cell culture represents a versatile approach for tumor stem cell expansion and tumor organoid generation
    Jueming Chen, Wang Xiao-gang, Weijie Ye, Hui Kang, Siyan Xiao, Jiayu Li, Lihui Wang, Dongguo Lin, D. Liu · 2026 · Lab on a Chip
  12. Fully synthetic nanofibrillar hydrogel for the growth and enzyme-free release of patient-derived ovarian tumor organoids
    Yixiong Duan, Yuchuan Jin, Yiyang Jia, Mingyue Zhao, Lang Bai, Shoujun Zhu, Zhentong Wei, Songling Zhang, Bai Yang, Yunfeng Li · 2025 · Biomaterials
  13. Integrating inverse reinforcement learning into data-driven mechanistic computational models: a novel paradigm to decode cancer cell heterogeneity
    Patrick C. Kinnunen, Kenneth K. Y. Ho, Siddhartha Srivastava, Chengyang Huang, Wanggang Shen, Krishna Garikipati, Gary D. Luker, Nikola Banović, Xun Huan, Jennifer J. Linderman et al. · 2024 · Frontiers in Systems Biology
  14. Predicting patient treatment response and resistance via single-cell transcriptomics of their tumors
    Sanju Sinha, Rahulsimham Vegesna, Saugato Rahman Dhruba, Wei Wu, Daniel Lucas Kerr, Oleg V. Stroganov, Ivan V. Grishagin, Kenneth Aldape, Collin Michael Blakely, Peng Jiang et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Transcriptomic profiling of organoids derived from malignant effusions uncovers lncRNA MEG3 and target genes potentially involved in platinum resistance in serous ovarian carcinoma
    Naiade Calanca, Cláudia Aparecida Rainho, Debora Kazumi Maeda, Luiza Côrtes, Rolando André Rios Villacis, Daniela Bizinelli, Hellen Kuasne, Mads Malik Aagaard, Lars Ulrik Fokdal, Karina Dahl Steffensen et al. · 2025 · Biomedicine & Pharmacotherapy
  16. zAvatar-test—A functional precision model to personalize ovarian cancer treatments: Results from a co-clinical study
    Marta F Estrada, Filipa Amorim, Filipa Ferreira da Silva, Cátia Rebelo de Almeida, Márcia Fontes, Ricardo Coelho, Sónia Ferreira, Rita Canas‐Marques, Mireia Castillo-Martín, João Casanova et al. · 2025 · Cell Reports Medicine
  17. Targeting the DNA damage response prevents regrowth of colorectal peritoneal metastasis-derived organoids following treatment with mitomycin C
    Kyah van Megesen, Arianna Stefan, M.M. Kieboom, Rebecca Amico, Anne M. L. Jansen, Inne H.M. Borel Rinkes, Onno Kranenburg · 2026 · British Journal of Cancer
  18. Evaluating carboplatin and PARP inhibitor combination efficacy using high-grade serous carcinoma spheroids and organoids
    Emily J. Tomas, Jennifer Davis, Yudith Ramos Valdés, Trevor G. Shepherd · 2026 · Cancer Biology & Therapy
  19. Tumoroid model recreates clinically relevant phenotypes of high grade serous ovarian cancer cells, carcinoma associated fibroblasts, and macrophages
    Kathleen M Burkhard, Ayush Semwal, Benjamin K. Johnson, Kristina C. Chu, Riley Kranick, Mihika Rayan, Analisa V. DiFeo, Hui Shen, Geeta Mehta · 2026 · Acta Biomaterialia
  20. Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
    Shuangzhe Lin, Karthikeyan Narayanan, Deepak Vashishth · 2026 · Advanced Science
  21. The application and research advances of organoids in clinical medicine
    Shaobo Mo, Ruo‐Yu Guan, Zhang Long, Sanjun Cai, Junjie Peng, GuoQiang HUA · 2021 · Scientia Sinica Vitae
  22. Bridging the Scientific Gaps to Identify Effective Treatments in Adrenocortical Cancer
    Nicholas Michael, Naris Nilubol · 2022 · Cancers
  23. Generation, Expansion, and Biobanking of Gastrointestinal Patient-Derived Organoids from Tumor and Normal Tissues
    Manuel Cabeza-Segura, Blanca García-Micó, Andrès M.R. Cervantes, Josefa Castillo · 2024 · Methods in molecular biology
  24. Parallel Acceleration of Genome Variation Detection on Multi-Zone Heterogeneous System
    Yaning Yang, Xiaoqi Wang, Chengqing Li, Shaoliang Peng · 2025 · IEEE Transactions on Parallel and Distributed Systems
  25. A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing drugs in RB1-deficient ovarian and breast cancer cells
    Daria R. Bulanova, Yevhen A. Akimov, Wojciech Senkowski, Jaana Oikkonen, Laura Gall-Mas, Sanna H. Timonen, Manar Elmadani, Johanna Hynninen, Sampsa Hautaniemi, Tero A. Aittokallio et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Models of High-Grade Serous Ovarian Carcinoma
    Oscar J. Pundel, Benjamin G. Neel · 2025 · Cold Spring Harbor Perspectives in Medicine
  27. Vascularized tumor organoids enable immunotherapy testing in tumor-remodeled stroma
    Reiner Wimmer, Rok Krese, Louisa Henniger, Steve Niu, Nadege Lagarde, Timon Keller, Inga Clausen, Fabian Köchel, Claudia Ferrara, Inja Waldhauer et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Technological advances in clinical individualized medication for cancer therapy: from genes to whole organism
    Jiejing Kai, Xueling Liu, Meijia Wu, Pan Liu, Meihua Lin, Hongyu Yang, Qingwei Zhao · 2025 · Personalized Medicine
  29. Establishment and Characterization of a Durable and Versatile Endometrial Cancer Organoid Database
    Yifen Li, Gangwei Wang, Jianwei Chen, Xingping Xu, Tao Xu, Xuefeng Jiang, Yu Zhang · 2025 · Indian Journal of Gynecologic Oncology
  30. An organoid-guided platform for ovarian cancer: enabling prediction of patients’ chemotherapy response
    Ling Wang, Misi He, Xueping Zhu, Lifang Ma, Lin Zhong, Qingxiu Jiang, Qiaoling Li, Hongji Wu, Haixia Wang, Dongling Zou · 2026 · Journal of Ovarian Research
  31. Tumor Microenvironment of Epithelial Ovarian Cancer
    Rachel S. Perkins, Won-Young Choi, Matthew S. Jung and; Wenjing Zhang · 2025 · IntechOpen eBooks
  32. A 3D ovarian cancer metastasis model using a decellularised peritoneal matrix to study therapy response
    Christiane Helgestad Gjerde, Katrin Kleinmanns, Anika Langer, Gorka Ruiz de Garibay Ponce, Ezekiel R. Rozmus, Gina Nyhus Stangeland, Calum Leitch, Rammah Elnour, Harsh Dongre, Constantin Berger et al. · 2026 · EBioMedicine
  33. Engineering immune-competent niches: strategies, applications, and translational hurdles in ovarian cancer organoid models
    Yuying Chen, N. L. Jing Xu, Mingxin Dong, Wensen Liu, Ziwei Liu, Guangchao Sun, Yan Jia · 2026 · Frontiers in Immunology
  34. An organoid-guided roadmap for precision delivery of epigallocatechin gallate in oral submucous fibrosis
    Chenpeng Chen, An Gan, Chenggong Huang, Yishun Weng, Tao Wang · 2026 · Frontiers in Bioengineering and Biotechnology
  35. Recent Applications of Tissue-Engineered 3D Scaffolds in Oncology: Present and Future Perspectives
    Devika Tripathi, Vivek Kumar Gupta, Prashant Kumar Pandey · 2026 · Protein and Peptide Letters
  36. Patient-derived ovarian cancer organoids as platforms for predicting platinum resistance and screening tumor stem cell inhibitors
    Mingxia Ye, Yawen Wu, Zexin Chen, Qingzhi Zhai, Lian Li, Zhifeng Yan, Mingxia Li, Chenglei Gu, Wen Yang, Shujie Liao et al. · 2026 · Drug Resistance Updates
  37. Correlation between recognition of autologous tumor organoids by tumor-infiltrating lymphocytes from metastatic epithelial cancers and clinical response
    Alexandra M. Gustafson, Aarushi Bhasin, Billel Gasmi, Brian D. Bui, Catherine M. Ade, Ken‐ichi Hanada, Hyunmi K. Halas, Jared J. Gartner, Todd D. Prickett, Jon Salazar et al. · 2026 · Journal for ImmunoTherapy of Cancer
  38. Patient-Derived Organoids in Clinical Medicine: Proven Impact and Future Directions
    Magdalena Skowrońska, Ece Yıldız, Jens Grosch, Mairene Coto‐Llerena · 2026 · Organoids
  39. Nanoscale Drug Delivery Systems for Ovarian Cancer: Targeting Strategies, Theranostic Platforms, and Translational Challenges
    Xinyue Hu, Yu Zhang, Yueda Lu, Fangqi Zheng, Kaiyu Zhang, Mengxing Jiang, Chen Chen, Zhaolian Wei, Jianye Wang · 2026 · Small
  40. A pH-sensitive nanococktail enabled cancer stem cell elimination, deep tumour penetration, and tumour shrinkage
    Kamel S. Ahmed, Emma Nolan, Jingjing Wang, Stephen M. F. Jamieson, Patrick Pan, Dengxuan Mao, David J.T. Porter, George Robert Laking, Nianping Feng, Andrew Neil Shelling et al. · 2026 · International Journal of Pharmaceutics
  41. Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities
    Hui–Hsuan Kuo, Bhavneet Bhinder, Hamza Numan Gokozan, Kathryn Gorski, Pooja Chandra, Jyothi Manohar, Daniela E. Guevara, John R. Otilano, Jenna E. Moyer, Marvel Tranquille et al. · 2026 · Science Advances
  42. Cytotoxic effect of 13α-estrane derivatives on breast, endometrial and ovarian cancer cell lines
    Alja Zottel, Rebeka Jójárt, Henrietta Ágoston, Eva Hafner, Neža Lipušček, Erzsébet Mernyák, Tea Lanišnik Rižner · 2023 · The Journal of Steroid Biochemistry and Molecular Biology
  43. Tumor Ecosystem-Mimicking Bioengineering Methods
    Phei Er Saw, Erwei Song · 2023 · Springer eBooks
  44. Response to Systemic Therapies in Patient-Derived Cell Lines from Primary and Recurrent Adult Granulosa Cell Tumors
    Geertruid Johanna Brink, Nizar Hami, Sander Mertens, Hans W. Nijman, Luc R.C.W. van Lonkhuijzen, Eva Maria Roes, Christianne A. R. Lok, Cor Doede de Kroon, Jurgen M.J. Piek, Ward Hofhuis et al. · 2024 · Molecular Cancer Therapeutics
  45. Therapeutic Effects of Lurbinectedin in PARP Inhibitor-Resistant High-Grade Serous Ovarian Cancer Using Patient-Derived Cell Lines and Organoid Models
    Akshi Srivastava, Christine Unterweger, Sarah Guttmann, Andrea Wolf, Leonhard Müllauer, Martin Schepelmann, Dan Cacsire Castillo‐Tong, Thomas Bartl · 2025 · International Journal of Molecular Sciences
  46. NPEPPS is a novel and druggable driver of platinum resistance
    Robert T. Jones, Mathijs Scholtes, Andrew E. Goodspeed, Maryam Akbarzadeh, Saswat Mohapatra, Lily Elizabeth Feldman, Hedvig Vékony, Annie Jean, Charlene B. Tilton, Michael V. Orman et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  47. ODFormer: a Virtual Organoid for Predicting Personalized Therapeutic Responses in Pancreatic Cancer
    Jing Xu, Xiaolu Yang, Yunguang Li, Huang Wang, Yikai Li, Shijie Tang, Shiwei Guo, Jiawei Zou, Xiaohan Shi, Zexi Chen et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  48. Intratumoral Cellular Heterogeneity Critically Determines Extracellular Vesicle Uptake in Colorectal Cancer
    Andrea Kelemen, Idan Carmi, Ádám Oszvald, Péter Lőrincz, Gábor Petővári, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener · 2021 · Research Square
  49. Leveraging technological opportunities in cancer genomics
    Jose Espejo Valle-Inclán · 2021
  50. Ovarian Cancer: Towards Personalizing Ovarian Cancer Treatments Using Patient-Derived Organoids
    Tatiana Volpari, Jacqueline Hebner, Raeka S. Aiyar, Laura A. Martin · 2021 · Elsevier eBooks
  51. Receptor tyrosine kinase signaling and extracellular matrix cues in ovarian cancer metastasis and drug resistance
    Lidia Moyano‐Galceran · 2021 · Figshare
  52. Dormant Cancer Cells: Molecular Features, in vitro Models, and Identification Methods
    Sergey V. Nikulin, B. Yа. Alekseev · 2021 · Biotekhnologiya
  53. Using Genetically Encoded Fluorescent Biosensors to Interrogate Ovarian Cancer Metabolism
    Shree Bose, Haipei Yao, Qiang Huang, Regina S. Whitaker, Christopher D. Kontos, Rebecca A. Previs, Xiling Shen · 2022 · Research Square
  54. Establishment and Drug Screening of Patient-Derived Extrahepatic Biliary Tract Carcinoma Organoids
    Zhiwei Wang, Yinghao Guo, Yun Jin, Xiaoxiao Zhang, Hao Geng, Guangyuan Xie, Dan Ye, Yuanquan Yu, Daren Liu, Donger Zhou et al. · 2021 · Research Square
  55. Tumor heterogeneity in glioblastoma
    Maikel Verduin · 2023
  56. A Novel ex-vivo platform for personalized treatment in metastatic ovarian cancer
    Alain Valdivia, Adebimpe Adefolaju, Morrent Thang, Luz Andrea Cuaboy, Catherine S. John, Breanna Mann, Andrew Satterlee, Victoria Lin Bae-Jump, Shawn Hingtgen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  57. Advances in organoid and related biospecimen repository research
    Teng HUANG, Lei CHEN, Hongyang Wang · 2024 · Scientia Sinica Vitae
  58. Current and future perspectives of xenograft models of human ovarian cancer
    Jun Inoue, Tatsuyuki Chiyoda, Tomoki Muramatsu, Akira Hirasawa, Daisuke Aoki, Johji Inazawa · 2024 · Elsevier eBooks
  59. Application of Cancer Organoids in Pharmacological Research
    Masahiro Inoue · 2024 · Drug Delivery System
  60. Organoids research progress in gynecological cancers: a bibliometric analysis
    Bing He, Haochuan Ma, Hongbo Yu, Dongmei Li, Li Zhang, Junjie Wang · 2024 · Frontiers in Oncology
  61. The new platform for cancer immunity research: Organoid systems
    Ming Tian, Qikun Wang, Tianyin Ma, Chengming Qu, Xiangdong Gongye, Yibo Chai, Shuxian Ma, Yufeng Yuan · 2024 · Elsevier eBooks
  62. A 3D ovarian cancer metastasis model using a decellularized peritoneal matrix to study therapy response
    Christiane Helgestad Gjerde, Katrin Kleinmanns, Anika Langer, Gorka Ruiz de Garibay Ponce, Ezekiel R. Rozmus, Gina Nyhus Stangeland, Calum Leitch, Rammah Elnour, Harsh Dongre, Constantin Berger et al. · 2024 · medRxiv
  63. Long-term patient-derived ovarian cancer organoids closely recapitulate tumor of origin and clinical response
    Lucie Thorel, Énora Dolivet, Pierre‐Marie Morice, Romane Florent, Jordane Divoux, Marion Perréard, Lucie Lecouflet, Guillaume Desmartin, Chloé Marde Alagama, Florence Giffard et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Phenotypic drug discovery
    Sonja Sievers, Herbert Waldmann, Slava Ziegler · 2025 · Elsevier eBooks
  65. Pan-Cancer PDOs Preserve Tumor Heterogeneity and Uncover Therapeutic Vulnerabilities
    Hui–Hsuan Kuo, Bhavneet Bhinder, Hamza Numan Gokozan, Kathryn Gorski, Pooja Chandra, Jyothi Manohar, Daniela E. Guevara, John R. Otilano, Jenna E. Moyer, Marvel Tranquille et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  66. Advancing clinical outcome predictions via incorporating pharmacokinetic simulations into in vitro testing - a colorectal cancer example
    Andrey A. Poloznikov, Ben R. Britt, Sergey V. Nikulin, Sergey Rodin, Karl‐Henrik Grinnemo, Martin Woywod, Jasmin Farouq · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  67. Vision Evaluation of Patient-Derived Organoids for Personalised Medicine
    Henrik Vogt, Maxence Gaillard, Sara Green · 2025 · SpringerBriefs in philosophy
  68. Vision Analysis of Patient-Derived Organoids for Personalised Medicine
    Henrik Vogt, Maxence Gaillard, Sara Green · 2025 · SpringerBriefs in philosophy
  69. Patient-Derived Organoids: Basic and Translational Research on Uterine Cancer
    Yoshiaki Maru, Naotake Tanaka, Yoshitaka Hippo · 2025 · Current human cell research and applications
  70. Nature‐Inspired MYC Inhibitor Disrupts MYC‐Driven Glycolysis and Restricts Ovarian Tumor Growth
    Mamta Singh, Anubha Yadav, Umesh Singh, Rajat Gupta, Enrico Cavarzerani, Vincenzo Canzonieri, Deepraj Negi, Akansha Dagar, Bharathwaj Sathyamoorthy, Flavio Rizzolio et al. · 2025 · ChemMedChem
  71. Discovery and targeted mass spectrometry-based proteomics of ovarian cancer
    Nicole E. Platzer, Amanda B. Hummon · 2025 · Expert Review of Proteomics
  72. Additional file 2 of Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer
    Jérôme Cartry, Sabrina Bedja, Alice Boilève, Jacques R.R. Mathieu, Emilie Gontran, Maxime Annereau, Bastien Job, Ali Mouawia, Pierre Mathias, Thierry de Baère et al. · 2024 · Figshare
  73. Additional file 3 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
    Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
  74. Additional file 2 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
    Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
  75. Additional file 1 of Establishment and drug screening of patient-derived extrahepatic biliary tract carcinoma organoids
    Wang, Zhiwei, Guo, Yinghao, Yun Jin, Zhang, Xiaoxiao, Geng, Hao, Guangyuan Xie, Ye, Dan, Yu, Yuanquan, Liu, Daren, Zhou, Donger et al. · 2021 · Figshare
  76. Additional file 1 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
    Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
  77. Additional file 1 of Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
    Lidwien Paula Smabers, G. Emerens Wensink, Carla S. Veríssimo, Esmee Koedoot, Pitsa, Katerina-Chara, Maarten A. Huismans, Celia Higuera Barón, Mayke Doorn, Liselot Valkenburg‐van Iersel, Geert A. Cirkel et al. · 2024 · Figshare
  78. Additional file 2 of Establishment and drug screening of patient-derived extrahepatic biliary tract carcinoma organoids
    Wang, Zhiwei, Yinghao Guo, Yun Jin, Xu Zhang, Geng, Hao, Guangyuan Xie, Ye, Dan, Yu, Yuanquan, Liu, Daren, Zhou, Donger et al. · 2021 · Figshare
  79. Additional file 4 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
    Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
  80. Additional file 1 of Sunitinib efficacy with minimal toxicity in patient-derived retinoblastoma organoids
    Atthapol Srimongkol, Natanan Laosillapacharoen, Duangporn Saengwimol, Vijender Chaitankar, Duangnate Rojanaporn, Thanastha Thanomchard, Suparerk Borwornpinyo, Suradej Hongeng, Rossukon Kaewkhaw · 2023 · Figshare
  81. Additional file 1 of Assessment of source material for human intestinal organoid culture for research and clinical use
    Paulo C. M. Urbano, Hamish C. K. Angus, Safina Gadeock, Michael Schultz, Roslyn A. Kemp · 2022 · Figshare
  82. Development and Application of Tumor Organoids: An Emerging Platform for Gynecological Cancers
    Yu Hu, Wei Chen, Xiaojing Zhang, Ying Wu, Furong Du, Jingrui Wang, Meijun He, Wei Tan Sun · 2025 · International Journal of Women s Health
  83. CELLULAR BIOTECHNOLOGIES IN THE MODELING OF CARCINOGENESIS AND THEIR POTENTIAL IN PRECISION MEDICINE
    Наханов Азиз Куралбаевич, Sabit Kabdyshevich Kokanov, A. A. Terebay, L. G. Marakhovskaya · 2026 · Biosafety and Biotechnology
  84. MRCKα represses GEF-H1 mediated RhoA activation to promote ovarian cancer spheroid growth and invasion
    Aasiya Remtulla, Alison Kurimchak, Alicia Canuel, Ishadi K. M. Kodikara, Jason S. Wasserman, Alexandre Chuyen, Danielle Olding, Rajesh Gupta, Nikolina Radulovich, James S. Duncan et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  85. Ascites-Driven Modulation of Cell Phenotypes and Proteomes: Implications for Cancer Progression
    Jack Scanlan, Parul Mittal, Jennifer M. Washington, Clifford Young, Martin Klaus Oehler, Peter Hoffmann, Manuela Klingler‐Hoffmann · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  86. Flavonoid GL-V9 as a novel and potent acetyl-coa carboxylase 1 inhibitor confers cisplatin hypersensitivity in ovarian cancer
    Zihao Jiang, Yelin Cai, Jie Zhu, Zeyuan Lu, Cong Wang, Baosheng Huang, Qinglong Guo, Hongchuan Zhang, Guo Chen, Yongjian Guo · 2026 · Phytomedicine
  87. Impact of non‐genetic heterogeneity of BRAF ‐mutant colon cancer organoids on growth kinetics, drug sensitivity and Wnt dynamics
    Viktoria Zieger, Ellen Woehr, Jasmin Traichel, Tilman Brummer, Roland Zengerle, Sabrina Kartmann, Stefan Zimmermann · 2026 · International Journal of Cancer
  88. Organoids in Personalised Oncology: Advances and Clinical Translation Toward Precision Cancer Therapy
    Shurong Hai, Xishun Zhou, Junbo Li, Xi Zeng, Qi Yu · 2026 · Scandinavian Journal of Immunology
  89. Innovative In Vitro-In Silico Platform for Dose–Response Modeling in Canine Bladder Cancer: A 3D Organoid- and Mathematics-Based Approach
    Mackenzie Long, Yvonne Peng, Saumya Gade, Hannah F. Nicholson, Michael Catucci, Christopher Zdyrski, Aleksandra Pawlak, Megan P. Corbett, Corey Saba, Travis Laver et al. · 2026 · The AAPS Journal
  90. Unmasking prostate cancer risk factors leveraging organoid technology
    Marta Cantarelli, Elisa Marmocchi, Andrea Lunardi, Rubens Begaj · 2026 · Gene
  91. Engineering in vitro models to target tumour recurrence
    Nila C. Wu, Ruonan Cao, Michelle Nurse, Alison P. McGuigan · 2026 · Trends in biotechnology
  92. Development of high throughput approaches to identify cancer-associated long noncoding RNAs
    Mohammad Ahmad · 2023
  93. Proposition d'une thérapie photodynamique ciblant FRα pour le traitement des métastases microscopiques des cancers épithéliaux de l'ovaire : Evaluation préclinique de son efficacité anti-tumorale et de ses propriétés adjuvantes immunostimulantes
    Léa Boidin · 2024
  94. Développement de nouvelles stratégies thérapeutiques dans les cancers de l’ovaire : intérêt de l’inhibiteur d’HDAC belinostat, seul ou associé avec des molécules BH3-mimétiques, et recherche de stratégies ciblées mimant les mécanismes moléculaires médiateurs de son efficacité
    Cécilia Thomine · 2023 · theses.fr (ABES)
  95. Evaluation de deux nouvelles stratégies thérapeutiques ciblant les exosomes tumoraux de Carcinomes du Nasopharynx (CNP) : Proposition d'une stratégie d'Immunothérapie ciblant la galectine-9 et d'une Thérapie Photodynamique au 5-ALA
    Camille Trioën · 2024
  96. Comprehensive drug efficacy data for mucinous ovarian carcinoma using a novel and extensive biobank of patient-derived organoid models
    Olivia Craig, Carolina Salazar, Suad M. Abdirahman, Nikita Dalvi, Niveditha Rajadevan, Jennii Luu, Robert Vary, Susanne Ramm, Karla J. Cowley, Ratana Lim et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  97. Deciphering mitochondrial metabolic vulnerabilities in ovarian clear cell carcinoma with mass spectrometry-based clinical proteomics
    Albert Barrios, Stefani N. Thomas · 2026 · Expert Review of Proteomics
  98. Translational 3D in vitro models for immunotherapy testing: from reconstituted organoid co-culture assays to autologous ex vivo patient tissues
    Saskia Madelon Ada de Man, Ezgi Kaya Aksoy, Tomas Veenendaal, Niels Meesters, Sergei Chavez-Abiega, Xuefei Yan, Michelle Kop, Luca Gandini, Jolie Flach, Jiawei Meng et al. · 2026 · Frontiers in Immunology
  99. Single-cell transcriptomics of heterogeneous patient-derived organoids reveals novel therapeutic targets in high-grade serous ovarian cancer
    Bisiayo Fashemi, Yukihide Ota, Vijayalaxmi G. Gupta, Maia Lina Elizagaray, Roger Piqué-Regi, Nardhy Gomez‐Lopez, Mary Mullen, Dineo Khabele · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Patient-Derived Organoids Functionally Stratify Epithelial Ovarian Cancer into Clinically Relevant Chemotherapy Response Phenotypes
    Shruthi Ragothaman, Raghuveer Reddy, Shelma Cheeran Sajan, Leah Achsah John, Viamaya Biju, Y Vipulachandra, Satish Sankaran, Rohit Raghunath Ranade, Smitha P.K. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)