Protein lactylation induced by neural excitation
Hagihara, Hideo, Shoji, Hirotaka, Otabi, Hikari, Toyoda, Atsushi, Katoh, Kaoru, Namihira, Masakazu, Miyakawa, Tsuyoshi·2021·Cell Reports
Cited by (357)
Items 101–200 of 357
- Mechanisms for Regulatory Effects of Exercise on Metabolic Diseases from the Lactate–Lactylation PerspectiveGuannan Chen, Jinchao Liu, Yilan Guo, Peng Sun · 2025 · International Journal of Molecular Sciences
- H4K79 and H4K91 histone lactylation, newly identified lactylation sites enriched in breast cancerJiena Liu, Li Zhao, Meisi Yan, Shengye Jin, Lingmin Shang, Jianyu Wang, Qin Wang, Shilu Zhao, Zibo Shen, Tong Liu et al. · 2025 · Journal of Experimental & Clinical Cancer Research
- Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male miceHaiyan Li, Ayako Kawatake-Kuno, Hiromichi Inaba, Yuka Miyake, Yukihiro Itoh, Takatoshi Ueki, Naoya Oishi, Toshiya Murai, Takayoshi Suzuki, Shusaku Uchida · 2024 · Neuron
- Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brainYuhan Han, Weiji Weng, Yongkang Zhang, Qiyuan Feng, Yuxiao Ma, Ankang Quan, Xianhua Fu, Xinxin Zhao, Loren Skudder‐Hill, Jiyao Jiang et al. · 2024 · Biomaterials
- A glimpse into novel acylations and their emerging role in regulating cancer metastasisHuifang Shi, Weigang Cui, Yan Qin, Lei Chen, Tao Yu, Jie Lv · 2024 · Cellular and Molecular Life Sciences
- Histone H3 lysine 18 lactylation attenuates neuroinflammation and neurological damage by regulating microglial plxnb2 after ischemic strokePing Li, Yao Wang, Yuan Xu, Linyu Feng, Na Jiang, Yongkang Fang, Guini Song, Lingling Yu, Li Xu, Zhou Zhu et al. · 2025 · Neurobiology of Disease
- Lactate and Lactylation: Clinical Applications of Routine Carbon Source and Novel Modification in Human DiseasesZhimin Wang, Dan Hao, Shuiying Zhao, Ziyin Zhang, Zhen Zeng, Xiao Qin Wang · 2023 · Molecular & Cellular Proteomics
- Insight into the roles of lactylation in macrophages: functions and clinical implicationsMin Shu, Dingci Lu, Ziyi Zhu, Fei Yang, Zhaowu Ma · 2025 · Clinical Science
- Amphiregulin contributes to neuropathic pain by enhancing glycolysis that stimulates histone lactylation in sensory neuronsYu-Tao Deng, Longfei Ma, Yixiao Mei, Ji-Shuai Wang, Xue‐Hui Bai, Xuan-Jie Zheng, Jinxuan Ren, Da Zhong, Bing-Lin Zhou, Jia Dan et al. · 2025 · Science Signaling
- Lactylation: a promising therapeutic target in ischemia-reperfusion injury managementFeixiang Wang, Guo Mu, Zihang Yu, Zu-an Shi, Xuexin Li, Xin Dong Fan, Ye Chen, Jun F. Zhou · 2025 · Cell Death Discovery
- Hypoxia facilitates stemness of colon cancer cells via histone lactylationQi Zhang, Zhenzhen Han, Jia-Hui Liu, Munan Li, Wei Li, Xin Min ZHOU, Xuelian Liu · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Glypican-3 knockdown inhibits the cell growth, stemness, and glycolysis development of hepatocellular carcinoma cells under hypoxic microenvironment through lactylationGebing Yao, Zihua Yang · 2023 · Archives of Physiology and Biochemistry
- Lactylation: From Homeostasis to Pathological Implications and Therapeutic StrategiesXi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang · 2025 · MedComm
- H3K14 lactylation exacerbates neuronal ferroptosis by inhibiting calcium efflux following intracerebral hemorrhagic strokeTingting Sun, Jian-Nan Zhang, Ting Lan, Lei Shi, Liye Hu, Liyan Yan, Chao Wei, Lisha Hei, Weihua Wu, Zhaoli Luo et al. · 2025 · Cell Death and Disease
- The lactylation-macrophage interplay: implications for gastrointestinal disease therapeuticsXinzhen Che, Yixin Zhang, Xiqi Chen, Guangdong Xie, Jinling Li, Chengchao Xu, Chunhua Zhang, Yong Zhu, Xinyu Yang · 2025 · Frontiers in Immunology
- The role of protein lactylation in brain health and disease: current advances and future directionsMingrui Han, Wenfeng He, Wengen Zhu, Linjuan Guo · 2025 · Cell Death Discovery
- Hippocampal Lactate-Infusion Enhances Spatial Memory Correlated with Monocarboxylate Transporter 2 and LactylationYuhan Wu, Hui Hu, Weiwei Liu, Yun Fu Zhao, Fang Xie, Zhaowei Sun, Ling Zhang, Huafeng Dong, Xue Bing Wang, Lingjia Qian · 2024 · Brain Sciences
- Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in TendinopathyYuan Yu Lin, Ming Chen, Duanyang Wang, Yang Yü, Ruijing Chen, Mingming Zhang, Haikuan Yu, Xiang Huang, Man Rao, Yezhou Wang et al. · 2023 · Journal of Proteome Research
- Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung AdenocarcinomaJizhuo Li, Wenze Xun, Xijie Wang, Ruiguang Luo, Qifan Hu, Zhaocai Zhou, Jian Yuan, Yanan Wang, Xiaorui Wan, Tao Zhao et al. · 2025 · Advanced Science
- A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesisJingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji M. Mishina · 2024 · Journal of Clinical Investigation
- Lactate: a pearl dropped in the ocean—an overlooked signal molecule in physiology and pathologyYue Xiu Wu, Wanqi Ma, Wei Liu, Shuping Zhang · 2022 · Cell Biology International
- New Histone Lysine Acylation Biomarkers and Their Roles in Epigenetic RegulationQianyun Fu, Amber Cat, Yujun George Zheng · 2023 · Current Protocols
- Enhanced lactate accumulation upregulates PD‐L1 expression to delay neutrophil apoptosis in sepsisMiaomiao Fei, Hui Zhang, Fanbing Meng, Guanghui An, Jinxuan Tang, Jianbin Tong, Lize Xiong, Qidong Liu, Cheng Li · 2023 · Open Research (University of Surrey)
- Epigenetic mechanisms in depression: Implications for pathogenesis and treatmentHong-Sheng Chen, Fang Wang, Jianguo Chen · 2024 · Current Opinion in Neurobiology
- LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney diseaseZhibin Fan, Yue Zhang, Liming Yuan, Yuan Gao, Xiaoxi Tian, Jin Tian, Jie Wan, Bingyu Li, Xiaoqi Wang, Shuo Wang et al. · 2025 · Cellular Signalling
- Lactate: a prospective target for therapeutic intervention in psychiatric diseaseYanhui Cai, Haiyun Guo, Tianle Han, Huaning Wang · 2023 · Neural Regeneration Research
- Novel post-translational modifications of protein by metabolites with immune responses and immune-related molecules in cancer immunotherapyLihua Chen, Lixiang Huang, Yu Gu, Chen Li, Pengming Sun, Yang Xiang · 2024 · International Journal of Biological Macromolecules
- Metabolic reprogramming of astrocytes: Emerging roles of lactateZeyu Liu, Yijian Guo, Ying Zhang, Yulei Gao, Bin Ning · 2024 · Neural Regeneration Research
- The Roles of Lactate and Lactylation in Diseases Related to Mitochondrial DysfunctionFei Ma, Wei Yu · 2025 · International Journal of Molecular Sciences
- Deciphering the Atlas of Post-Translational Modification in SugarcaneQibin Wu, Zhenxiang Li, Jingtao Yang, Fu Xu, Xueqin Fu, Liping Xu, Chuihuai You, Dongjiao Wang, Yachun Su, Youxiong Que · 2023 · Journal of Agricultural and Food Chemistry
- Lactylation Modification in Cardiometabolic Disorders: Function and MechanismXu Li, Pingdong Cai, Xinyuan Tang, Yingzi Wu, Yue Zhang, Xianglu Rong · 2024 · Metabolites
- ChIP-seq and RNA-seq Reveal the Involvement of Histone Lactylation Modification in Gestational Diabetes MellitusXiaman Huang, Ka Cheuk Yip, Hanhui Nie, Ruiping Chen, Xiufang Wang, Yun Wang, Weizhao Lin, Ruiman Li · 2024 · Journal of Proteome Research
- The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and lactylationPeter W. Stacpoole, Carolyn O. Dirain · 2024 · Molecular Genetics and Metabolism
- Lactylation in Tumor Immune Escape and Immunotherapy: Multifaceted Functions and Therapeutic StrategiesQing Li, Runkang Zhao, Yang Shen, Dandan Guo, Lvdan Deng, Rong Cai, Zhijun Shen, Zhao Xie, Na Hang, Shuai Fu et al. · 2025 · Research
- The role of post-translational modifications in driving abnormal cardiovascular complications at high altitudeJun Hou, Xudong Wen, Pan Long, Shiqiang Xiong, Hanxiong Liu, Lin Cai, Haoyu Deng, Zhen Zhang · 2022 · Frontiers in Cardiovascular Medicine
- Association of histone modification with the development of schizophreniaChen, Yun-zhou, Zhu, Xiu-mei, Lv, Peng, Hou, Xi-kai, Pan, Ying, Li, Ang, Du, Zhe, Xuan, Jin-feng, Guo, Xiaochong, Xing, Jia-xin et al. · 2024 · Biomedicine & Pharmacotherapy
- Lactylated histone H3K18 as a potential biomarker for the diagnosis and prediction of the severity of pancreatic cancerJinping Hou, M. Guo, Yongqiong Li, Yijin Liao · 2024 · Clinics
- H4K12 Lactylation Activated‐ Spp1 in Reprogrammed Microglia Improves Functional Recovery After Spinal Cord InjuryXiaokun Wang, Geliang Zhou, Junjun Xiong, Ye Wu, Yu Gao, Haofan Wang, Dishui Pan, Yongjun Luo, Zheng Zhou · 2025 · CNS Neuroscience & Therapeutics
- Lactylation in cancer: molecular mechanisms and advances in clinical studyJiale Li, Changfeng Miao, Haijun Guo, Maximo Lin, Rui Chen, Jun Peng, Jiachong Wang, Chunhai Tang, Zigui Chen · 2026 · Molecular Cancer
- Comprehensive analysis of lysine lactylation in Frankliniella occidentalisDong An, Liyun Song, Ying Li, Lili Shen, Pu Miao, Yujie Wang, Dongyang Liu, Lianqiang Jiang, Fenglong Wang, Jinguang Yang · 2022 · Frontiers in Genetics
- Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairmentHideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori et al. · 2023 · eLife
- Extracellular lactate improves neurogenesis by modulating H3K9 lactylation and SnoN expression under hypoxic conditionsWenhong Xu, Anqi Zhao, Rui Han, Junyuan Wei, Qi Yu, Miaomiao Wang, Haokun Li, Baofeng Xu, Meiying Li, Guangfan Chi · 2025 · Stem Cell Research & Therapy
- The C10orf76–PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal GolgiAya Mizuike, Shota Sakai, Kaoru Katoh, Toshiyuki Yamaji, Kentaro Hanada · 2023 · The Journal of Cell Biology
- Lactylation prediction models based on protein sequence and structural feature fusionYehong Yang, Juntao Yang, Jiang-Feng Liu · 2024 · Briefings in Bioinformatics
- From energy metabolism to mood regulation: The rise of lactate as a therapeutic targetSen Zhang, Jie Xia, Wenke He, Yong Zou, Wenbin Liu, Lingxia Li, Zhuochun Huang, Qing Li, Qing X. Li, Weina Liu · 2025 · Journal of Advanced Research
- Protein lactylation in cancer and other pathologies: Epigenetic regulation of glycolysis and its therapeutic perspectivesYaowen Zhang, Jianxiang Wang, Cong Li, Zhe Lei, Xiang Zhao, Xuan Xuan, Olga A. Sukocheva, Edmund Tse, Junqi Liu · 2025 · Seminars in Cancer Biology
- The characterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse heartsTongyu Zhang, Yingxi Zhu, Xiaochen Wang, Danyang Chong, Haiquan Wang, Dandan Bu, Mengfei Zhao, Lei Fang, Chaojun Li · 2024 · Journal of genetics and genomics/Journal of Genetics and Genomics
- Polysaccharide extracted from Sarcandra glabra residue attenuate cognitive impairment by regulating gut microbiota in diabetic miceMeng Ye, Yameng Liu, Feng Wang, Xiyuchen Yang, Xiao-Bing Yang, Xiangdong Gao, Wei Liu, Juping Yu · 2024 · International Journal of Biological Macromolecules
- New insights into the roles of lactylation in cancerYajun Emily Zhu, Wenhui Liu, Zhiying Luo, Feiyan Xiao, Bao Sun · 2024 · Frontiers in Pharmacology
- Lactylation in CNS disorders: mechanisms, cellular function, and disease relevanceJiaxin Tian, Tongyu Zhang, Ruidan Zhang, Sijia Hao, Jingyu Dong, Yiyan Chen, Jinpeng Zhou, Yang Tian · 2025 · Frontiers in Cell and Developmental Biology
- Protein Post-Translational Modifications Based on Proteomics: A Potential Regulatory Role in Animal ScienceShuhao Fan, Chengcheng Kong, Ren Zhou, Xianrui Zheng, Da‐long Ren, Zongjun Yin · 2024 · Journal of Agricultural and Food Chemistry
- Lactylation and Central Nervous System DiseasesYe Chen, Dongqiong Xiao, Xihong Li · 2025 · Brain Sciences
- Mitochondria at the crossroad of dysregulated inflammatory and metabolic processes in bipolar disordersJérémy Bernard, Ryad Tamouza, Ophélia Godin, Michael Berk, Ana C. Andreazza, Marion Leboyer · 2024 · Brain Behavior and Immunity
- Lactate promotes H3K18 lactylation in human neuroectoderm differentiationYu Wu, Yumeng Wang, Yu Dong, Ling V. Sun, Yufang Zheng · 2024 · Cellular and Molecular Life Sciences
- Histone lactylation mediated by Fam172a in POMC neurons regulates energy balanceZhuo Chen, Baocheng Wan, Hong Zhang, Lina Zhang, Rong Zhang, Lianxi Li, Yi Zhang, Cheng Hu · 2024 · Nature Communications
- The lactate metabolism and protein lactylation in epilepsyXi Kuang, Shuang Chen, Qingmei Ye · 2025 · Frontiers in Cellular Neuroscience
- Potential of lactylation as a therapeutic target in cancer treatment (Review)Zhengfeng Zhu, Xi Zheng, Pengfei Zhao, Cheng Chen, Gang Xu, Xixian Ke · 2025 · Molecular Medicine Reports
- How lactate and lactylation shape the immunity system in atherosclerosis (Review)Yan Xiong, Jie Zhou, Junru Wang, Hui Huang · 2025 · International Journal of Molecular Medicine
- Role of Histone Lactylation in Neurological DisordersYu‐Mo Zhang, Fei Yang, Qian Li, Jian-Nan Zhang · 2025 · International Journal of Molecular Sciences
- Lactylation in Cardiovascular Diseases: Current Progress and PerspectivesZhi‐Mo Wang, Qingwen Yu, Cong Wang, Shuhui Wang, Pei Wang, Lirong Zhang, Shengna Han · 2025 · Journal of the American Heart Association
- Mitochondria and Epigenetic Regulation: Bidirectional Crosstalk and Emerging Mitochondria-Targeted Degron ToolsYingwei Xu, Xiaokun Jian, Lei Shi, Lisa S. Shock, Lanming Chen, Louise T. Chow, Hengbin Wang · 2026 · Cells
- The role of nonhistone lactylation in diseaseHao Yu, Tingting Zhu, Dongwen Ma, Xiaohan Cheng, Shengjia Wang, Yongzhong Yao · 2024 · Heliyon
- P300-Mediated ARRB1 Lactylation Promotes Mitochondrial Dysfunction and Neuronal Apoptosis in Subarachnoid Hemorrhage Via Upregulating S100A9Kewei Mi, Zigui Chen, Jun He, Chonghua Jiang, Ying Xia, Jun Peng · 2025 · Neurochemical Research
- Neurological mechanism-based analysis of the role and characteristics of physical activity in the improvement of depressive symptomsWang, Nan, Zhu, Shanshan, Chen, Shuyang, Zou, Ju, Zeng, Peng, Tan, Sijie · 2025 · Reviews in the Neurosciences
- Metabolic toxicity and neurological dysfunction in methylmalonic acidemia: from mechanisms to therapeuticsMengmeng Du, Miaomiao Li, Shengnan Wu, Xue Wu, Yongxing Chen, Changlian Zhu · 2025 · Molecular Medicine
- Mitochondrial lactate venting limits oxidative stressDaniela Rauseo, Yasna Contreras‐Baeza, Mildreth Salazar, Abigail J. Galarza, Sebastián Holtheuer-Gallardo, Hugo Faurand, Nátali Cárcamo‐Lemus, Raibel Suárez, Joel L. Asenjo, Alexandra von Faber-Castell et al. · 2026 · Cell Metabolism
- The role of novel protein acylations in cancerDan Cao, Wenxuan Sun, Xinyi Li, Lian Jian, Xinran Zhou, Ann M. Bode, Xiangjian Luo · 2024 · European Journal of Pharmacology
- Lactate: Beyond a mere fuel in the epileptic brainXiang Chen, Xinjian Zhu · 2024 · Neuropharmacology
- Lactate-induced lactylation: from basic research to clinical perspectivesHenghe Shi, Yifei Zou, Sijie Jin, Junduo Wu, Bin Liu · 2025 · Frontiers in Pharmacology
- Lactate lactylation in neural pathophysiology: Bridging metabolism and neurodegenerationMengran Cao, Zhaoyang Yin, Wenrui Hu, Ying Luo, Qinglu Wang, Panpan Dong · 2025 · Neuroscience
- Spatiotemporal crosstalk among mitochondrial dynamics, NLRP3 inflammasome activation, and histone lactylation drives α-synuclein pathology in prodromal Parkinson’s diseasePeng Lv, Xia Chen, Shiping Liu, Yu Zhang, Yan Bai, Shun Wang, Yulin Wang · 2025 · Frontiers in Cellular Neuroscience
- Ultrathin Niobium Carbide MXenzyme for Remedying Hypertension by Antioxidative and Neuroprotective ActionsHui Min Yang, Lili Xia, Xuanxuan Ye, Jiayi Xu, Tianfeng Liu, Linping Wang, Shuai Zhang, Wei Jie Feng, Dongshu Du, Yu Chen · 2023 · Angewandte Chemie
- Lactate: A Theranostic Biomarker for Metabolic Psychiatry?Edward Caddye, Julien Pineau, Joshua Reyniers, Itamar Ronen, Alessandro Colasanti · 2023 · Antioxidants
- Unpacking the complexity of nuclear IL-33 (nIL-33): a crucial regulator of transcription and signal transductionZengbin Wang, Nanhong Tang · 2023 · Journal of Cell Communication and Signaling
- Oxidative stress regulates the catalytic activity and mitochondrial localization of HK2 in trophoblast by regulating K346 lactylationZhirui Chen, Lingling Wan, Mengying Wu, Yun Zhao, Haixia Huang, Qiuyi He, Ying Wang, Qing-Qing Luo · 2025 · The FASEB Journal
- H3K18 lactylation potentiates microglial polarization via the TLR4 pathway in diabetes-induced cognitive impairmentYing Yang, Fei Chen, Lulu Song, Liping Yu, Jinping Zhang, Bo Zhang · 2025 · JCI Insight
- Integration and Intersection of Cancer Metabolism with Epigenetic Pathways in GliomasSiva Kumar Natarajan, Matthew J Pun, James Haggerty-Skeans, Sriram Venneti · 2025 · Annual Review of Pathology Mechanisms of Disease
- Global Analysis of Lysine Lactylation of Germinated Seeds in WheatJunke Zhu, Weiwei Guo, Yubin Lan · 2023 · International Journal of Molecular Sciences
- Fibroblast growth factor 21 enhances learning and memory performance in mice by regulating hippocampal L-lactate homeostasisJiaojiao Xie, Jiapin Yan, Keru Ji, Yuejun Guo, Sibei Xu, Danjie Shen, Chen Li, Hongchang Gao, Liangcai Zhao · 2024 · International Journal of Biological Macromolecules
- Lactylation Modification as a Promoter of Bladder Cancer: Insights from Multi-Omics AnalysisYipeng He, Lingyan Xiang, Jingping Yuan, Honglin Yan · 2024 · Current Issues in Molecular Biology
- The Functions and Regulatory Mechanisms of Histone Modifications in Skeletal Muscle Development and DiseaseZining Huang, Linqing Hu, Zhiwei Liu, Shanshan Wang · 2025 · International Journal of Molecular Sciences
- Regulating the activity of GABAergic neurons in the ventral pallidum alters the general anesthesia effect of propofolYue Xi Zhou, Wei Dong, Yongkang Qiu, Ke-Jie Shao, Zi-Xin Zhang, Jia-Qi Yao, Tian-Qi Chen, Zi-Yi Li, Chen-Rui Zhou, Xin‐Hao Jiao et al. · 2024 · Neuropharmacology
- New Posttranslational Modification Lactylation Brings New Inspiration for the Treatment of Rheumatoid ArthritisYue Yang, Jinjie Shi, Jiming Yu, Xin Zhao, Ke Zhu, Shen Wang, Xinwen Zhang, Xieyu Zhang, Guangcheng Wei, Wei Cao · 2024 · Journal of Inflammation Research
- Lactic acid contributes to the emergence of depression-like behaviors triggered by blue light exposure during sleepYinhan Li, Xinhui Zou, Ying Ma, Jiaqi Cheng, Xiangmin Yu, Wenya Shao, Fuli Zheng, Zhenkun Guo, Guangxia Yu, Siying Wu et al. · 2025 · Ecotoxicology and Environmental Safety
- Histone lactylation-derived prelamin A accelerates pulmonary arterial smooth muscle cells senescence in hypoxia-induced pulmonary hypertension ratsJing Zhang, Meng-Yi Luo, Nan-Ping Li, Na Liang, Yun-Hua Yang, Yu-Rong Zhang, Gang-Kai Tan, Tong Xie, Shao-Xin Gong, Aiping Wang · 2025 · International Immunopharmacology
- Lactylation in tumor: mechanisms and therapeutic potentialsDandan Wang, Hao Rong, Ke Ma, Jun Peng · 2025 · Frontiers in Immunology
- Lactylation: the regulatory code of cellular life activity and a barometer of diseasesXuebing Xu, Xuming Wu, Dandan Jin, Jie Ji, Tong Wu, Mengxiang Huang, Junpeng Zhao, Zihan Shi, Lirong Zhou, XuYang He et al. · 2025 · Cellular Oncology
- Protein lactylation in kidney diseasesYang Xu, Xinming Li, Zhiguo Mao, Cheng Xue · 2025 · Frontiers in Cell and Developmental Biology
- Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang · 2025 · International Journal of Molecular Medicine
- Lactate and Lactylation in Immune Cell Function and Autoimmune Diseases: Mechanisms and Therapeutic PotentialYiying Yang, Ying Zhang, Ke Liu, Huali Zhang, Xiaoxia Zuo, Muyao Guo · 2025 · Immunology
- Lactate metabolism and protein lactylation in cancerZhaoyun Liu, Aili Li, Ziyu Ma, Junzhu Wang, Xinyu Chen, Zhiwei Wang, Rong Fu · 2026 · Molecular Biomedicine
- Lactylation: A Novel Epigenetic Regulator of Cellular SenescenceCaiyu Sun, Jiaxuan Li, Lei Dong, Yakui Mou, Bei Zhang, Xicheng Song · 2025 · Aging and Disease
- Lysine lactylation: Regulatory mechanisms, role in health and disease, and its therapeutic potentialYan Xu, Guangming Zhang, Huayuan Wei, Anliu Zhao, Yujia Zheng, Yang Shao, Lin Yang, Xijuan Jiang · 2025 · Drug Discovery Today
- The Emerging Role of Lactate and Lactylation Modifications in the Pathophysiology of Atherosclerotic Cardiovascular DiseasesXianqiong Lu, Qiyuan Luo, Danfeng Yu, Yan He, Jiyu Chen · 2025 · Cardiovascular Drugs and Therapy
- Forebrain-specific conditional calcineurin deficiency induces dentate gyrus immaturity and hyper-dopaminergic signaling in miceHideo Hagihara, Hirotaka Shoji, Mahomi Kuroiwa, Isabella A. Graef, Gerald R. Crabtree, Akinori Nishi, Tsuyoshi Miyakawa · 2022 · Molecular Brain
- Novel Insights into Psychosis and Antipsychotic Interventions: From Managing Symptoms to Improving OutcomesAdonis Sfera, Hassan Imran, Dan O. Sfera, Jacob Anton, Zisis Kozlakidis, Sabine Hazan · 2024 · International Journal of Molecular Sciences
- Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairmentHideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Protein lactylation in broiler breast: Insights on occurrence mechanisms and the correlations with meat qualityZhenxin Wang, Tong Xing, Lin Zhang, Liang Zhao, Feng Gao · 2025 · Food Chemistry
- Comprehensive observation of histone lysine lactylation during gametogenesis of Drosophila melanogasterYoshiki Hayashi, Ban Sato, Rio Kageyama, Kenji Miyado, Daisuke Saito, Satoru Kobayashi, Natsuko Kawano · 2025 · Developmental Dynamics
- Reserpine Causes Neuroendocrine Toxicity, Inducing Impairments in Cognition via Disturbing Hypothalamic–Pituitary–Thyroid Axis in ZebrafishFengzhi Sun, Lijie Xia, Baokun Wang, Yanao Liu, Xiaotong Cui, Huijun Kang, Rostyslav S. Stoika, Kechun Liu, Meng Jin · 2025 · NeuroSci