Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity

Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua·2017·Cell Chemical Biology
DOI 10.1016/j.chembiol.2016.11.013

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  32. Additional file 6 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  33. Additional file 7 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  34. Additional file 5 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  35. Additional file 8 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  37. Additional file 4 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  38. Additional file 1 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  39. Additional file 2 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  40. Additional file 3 of PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
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  54. BindingDB Entry 50018393: A retrospective overview of PHGDH and its inhibitors for regulating cancer metabolism.
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  55. BindingDB Entry 50008414: Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor
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