The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Cellular Networks Involved in the Influenza Virus Life Cycle
Open accessAbstract
Influenza viruses cause epidemics and pandemics. Like all other viruses, influenza viruses rely on the host cellular machinery to support their life cycle. Accordingly, identification of host functions that participate in viral replication steps is of great interest to understand the mechanisms of the virus life cycle as well as to find new targets for the development of antiviral compounds. Multiple laboratories have used various approaches to explore host factors involvement in the influenza virus replication cycle. One of the most powerful approaches is an RNAi-based genome-wide screen, which has thrown new light on the search for host factors involved in virus replication. In this review, we examine the cellular genes identified to date as important for influenza virus replication in genome-wide screens, assess pathways that were repeatedly identified in these studies, and discuss how these pathways might be involved in the individual steps of influenza virus replication, ultimately leading to a comprehensive understanding of the virus life cycle.
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Citations
Cites
Identification of host proteins required for HIV infection through a functional genomic screen
Brass, A. L., Dykxhoorn, D. M., Benita, Y., Yan, N., Engelman, A., Xavier, R. J., Lieberman, J., & Elledge, S. J. (2008) · Science · doi:10.1126/science.1152725 · Cited by 1,449 · cited 2×
“Now, this technology offers a new exciting tool for the exploration of novel host genes involved in virus replication (Brass et al., 2008, 2009; Cherry et al., 2005; Goff, 2008; Hao et al., 2008; König et al., 2008, 2010; Krishnan et al., 2008; Li et al., 2009; Zhou et al., 2008).”
BackgroundReactome knowledgebase of human biological pathways and processes
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Cited by
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
Karlas, A., Machuy, N., Shin, Y., Pleissner, K.-P., Artarini, A., Heuer, D., Becker, D., Khalil, H., Ogilvie, L. A., Hess, S., et al. (2010) · Nature · doi:10.1038/nature08760 · Cited by 695
Influenza A viruses: new research developments
Medina, R. A., & García-Sastre, A. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2613 · Cited by 677
Influenza Virus-Host Interactome Screen as a Platform for Antiviral Drug Development
Watanabe, T., Kawakami, E., Shoemaker, J. E., Lopes, T. J. S., Matsuoka, Y., Tomita, Y., Kozuka-Hata, H., Gorai, T., Kuwahara, T., Takeda, E., et al. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.11.002 · Cited by 290
Self-citationGenome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication
Han, J., Perez, J. T., Chen, C., Li, Y., Benitez, A., Kandasamy, M., Lee, Y., Andrade, J., tenOever, B., & Manicassamy, B. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.045 · Cited by 266
Viral immune modulators perturb the human molecular network by common and unique strategies
Pichlmair, A., Kandasamy, K., Alvisi, G., Mulhern, O., Sacco, R., Habjan, M., Binder, M., Stefanovic, A., Eberle, C.-A., Goncalves, A., et al. (2012) · Nature · doi:10.1038/nature11289 · Cited by 262
Metadata
- Authors
- Watanabe, T., Watanabe, S., & Kawaoka, Y.
- Venue
- Cell Host & Microbe
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 7
- Issue
- 6
- Pages
- 427-439
- ISSN
- 1931-3128 (ISSN-L)
- OpenAlex
- W2060173726
- Cited by
- 321
- References
- 4
- FWCI
- 21.60
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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