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Association between recurrent miscarriages and organochlorine pesticide levels
Abstract
Objectives Recurrent miscarriage (RM) is a challenging medical problem because of its unknown pathogenesis and etiology in most of the cases. Recent studies suggest the role of persistent environmental pollutants such as organochlorine pesticides (OCPs) in the etiology of RM. The present study was conducted to investigate possible associations of OCPs in the pathogenesis of RM.Design and methods Blood OCP levels were analyzed in women with RM (cases) and women with normal full term delivery with live birth (controls) by using a gas chromatograph equipped with an electron capture detector.Results A statistically significant association (p=0.01) was observed between blood gamma-HCH levels and women with recurrent miscarriages.Conclusions This study suggests that high blood levels of gamma-HCH may be associated with risk of RM.
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“The number of previous miscarriages is a major determinant of miscarriage risk; the relationship is previous miscarriages. 83”
From Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss (2021) · cites this paper as [83]
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References 41 · Cited by 62
Metadata
- Authors
- Pathak, R., Mustafa, M., Ahmed, R. S., Tripathi, A. K., Guleria, K., & Banerjee, B. D.
- Affiliations
- University of Delhi (IN)
- Corresponding author
- Banerjee, B.D.
- Venue
- Clinical Biochemistry
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 43
- Issue
- 1-2
- Pages
- 131-135
- ISSN
- 0009-9120 (ISSN-L)
- OpenAlex
- W2008655564
- Cited by
- 62
- References
- 41
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 4 · 2020: 8 · 2019: 3 · 2018: 2 · 2017: 5 · 2016: 1 · 2015: 1 · 2014: 3 · 2013: 5 · 2012: 6
- FWCI
- 3.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pesticide Exposure and Toxicity
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Keywords
- recurrent pregnancy loss, organochlorine pesticides, lindane, environmental pollutants, reproductive toxicity
- MeSH terms
- Abortion, Habitual, Adult, Animals, Chromatography, Gas, Environmental Pollutants, Female, Humans, Hydrocarbons, Chlorinated, India, Pesticides, Pregnancy, Young Adult
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- CoChat. (2026). Citation check: Association between recurrent miscarriages and organochlorine pesticide levels. https://app.cochat.ai/papers/10.1016/j.clinbiochem.2009.09.019
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- Pathak, R., Mustafa, M., Ahmed, R. S., Tripathi, A. K., Guleria, K., & Banerjee, B. D. (2010). Association between recurrent miscarriages and organochlorine pesticide levels. Clinical Biochemistry. https://doi.org/10.1016/j.clinbiochem.2009.09.019