Impact of whey protein supplementation in a weight-loss intervention in rural dwelling adults: A feasibility study
Open accessAbstract
Background & aims Weight loss in older adults enhances physical function, but may lead to sarcopenia and osteoporosis. Whey protein is a low cost rich source of essential amino acids, may improve physical function. We evaluated the feasibility and acceptability of consuming whey protein in the context of a weight-loss intervention in older adults with obesity.Methods A 12-week pilot feasibility, non-randomized weight loss study of 28 older adults was conducted, consisting of individualized, weekly dietitian visits with twice weekly physical therapist-led group strengthening classes. Half consumed whey protein, three times weekly, following exercise. Preliminary efficacy measures of body composition, sit-to-stand, 6-min walk and grip strength and subjective measures of self-reported health and function were also evaluated.Results Of the 37 enrolled, 28 completed the study (50 % in the protein group). Attendance rates for protein vs. non-protein groups were 89.9 ± 11.1 % vs. 95.6 ± 3.4 % (p = 0.08). Protein consumption was high in those attending classes (90.3 %) as was compliance at home (82.6 %). Whey was pleasant (67.3 ± 22.1, range 30-100, above average), had little aftertaste, and was neither salty or sticky. All were compliant (0.64 ± 0.84, range 0-5, low = higher compliance). Both groups lost significant weight (protein vs. no protein, -3.45 ± 2.86 vs. -5.79 ± 3.08, p = 0.47); Sit-to-stand, 6-min walk, and gait speed were no different, grip strength was improved in the protein compared to the non-protein group (-2.63 kg vs. 4.29 kg; p < 0.001).Conclusions Our results suggest that whey protein is a low-cost and readily available nutritional supplement that can be integrated into a weight loss intervention.
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Sufficient dietary protein intake during weight loss in older adults may be achieved using whey protein supplementation.
“Sufficient dietary protein intake during weight loss in older adults may be achieved using whey protein supplementation [69].”
From Obesity pharmacotherapy in older adults: a narrative review of evidence (2025) · cites this paper as [69]
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References 45 · Cited by 3
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- [31]Monteyne A, Martin A, Jackson L, Corrigan N, Stringer E, Newey J, Whey protein consumption after resistance exercise reduces energy intake at a post-exercise meal. Eur J Nutr. 2018; 57: 585– 92. 27832366 PMC5845592
- Authors
- Batsis, J. A., Petersen, C. L., Cook, S. B., Al-Nimr, R. I., Driesse, T., Pidgeon, D., & Fielding, R.
- Affiliations
- Dartmouth College (US)
- University of New Hampshire (US)
- University of North Carolina at Chapel Hill (US)
- Tufts University (US)
- Corresponding author
- Batsis, John A.
- Venue
- Clinical Nutrition ESPEN
- Publisher
- Elsevier BV
- Published
- 2021-10
- Volume
- 45
- Pages
- 426-432
- ISSN
- 2405-4577 (ISSN-L)
- PMC
- PMC8502229
- OpenAlex
- W3185379409
- Cited by
- 3
- References
- 45
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 1
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Nutrition ESPEN (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Agriculture (58-1950-4-003)
- Burroughs Wellcome Fund
- National Center for Advancing Translational Sciences
- National Institutes of Health (R01AG067416)
- Dartmouth SYNERGY Clinical and Translational Science Institute (UL1TR001086)
- National Institute on Aging (K23AG051681)
- Centers for Disease Control and Prevention
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- whey protein supplementation, weight loss, older adults, obesity, physical function, grip strength, sit-to-stand, walking speed, resistance training, body composition, sarcopenia, osteoporosis, rural population, dietary adherence, acceptability
- MeSH terms
- Whey, Whey Proteins, Aged, Feasibility Studies, Humans, Weight Loss, Dietary Supplements
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