The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Immediate oral feeding in patients with mild acute pancreatitis is safe and may accelerate recovery—A randomized clinical study
Open accessAbstract
Background & aims In acute pancreatitis, traditional treatment has been initial fasting on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. The aim of the present study was to evaluate the efficacy and feasibility of immediate oral feeding as compared to traditional fasting in patients with mild acute pancreatitis. Methods Sixty patients were randomized to the two treatment groups, fasting or immediate oral feeding. The inclusion criteria were pancreas amylase > or =3 times above normal, onset of abdominal pain within 48 h, acute physiological and chronic health evaluation (APACHE) score Results The groups were comparable with respect to age, sex, etiology, APACHE, time from onset of pain and amylase at admission. No significant differences were seen between the groups concerning levels of amylase, CRP, leukocytes, abdominal pain or number of gastrointestinal symptoms. The LOHS was significantly shorter in the oral feeding group (4 vs. 6 days; p Conclusions No signs of exacerbation of the disease process were seen in terms of significant differences between treatment groups for amylase or systemic inflammatory response. In mild acute pancreatitis, immediate oral feeding was feasible and safe and may accelerate recovery without adverse gastrointestinal events.
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“Starting early feeding with clear liquids, soft diet, low-fat diet,”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [196]
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A Clinically Based Classification System for Acute Pancreatitis
Bradley, E. L. (1993) · Archives of Surgery · doi:10.1001/archsurg.1993.01420170122019 · Cited by 2,748
Kalfarentzos, F. E., Kehagias, J., Mead, N., Kokkinis, K., & Gogos, C. A. (1997) · British journal of surgery · doi:10.1046/j.1365-2168.1997.02851.x · Cited by 627
Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis
Marik, P. E., & Zaloga, G. P. (2004) · BMJ · doi:10.1136/bmj.38118.593900.55 · Cited by 469
Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis
McClave, S. A., Greene, L. M., Snider, H. L., Makk, L., Cheadle, W. G., Owens, N. A., Dukes, L. G., & Goldsmith, L. J. (1997) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860719702100114 · Cited by 434
A Randomized Study of Early Nasogastric versus Nasojejunal Feeding in Severe Acute Pancreatitis
Eatock, F., Chong, P., Menezes, N., Murray, L., McKay, C. J., Carter, C. R., & IMRIE, C. W. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40587.x · Cited by 430
Parenteral Nutrition Is Associated With Intestinal Morphologic and Functional Changes in Humans
Buchman, A. L., Moukarzel, A. A., Bhuta, S. M., Belle, M., Ament, M. E., Eckhert, C. D., Hollander, D., Gornbeln, J., Kopple, J. D., & Vijayaroghavan, S. R. (1995) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607195019006453 · Cited by 410
Disturbances of the microcirculation in acute pancreatitis
Cuthbertson, C. M., & Christophi, C. (2006) · British journal of surgery · doi:10.1002/bjs.5316 · Cited by 319
ESPEN Guidelines on Parenteral Nutrition: Pancreas
Gianotti, L. V., Meier, R. F., Lobo, D. N., Bassi, C., Dejong, C. H. C., Ockenga, J., Irtun, Ø., & Macfie, J. M. (2009) · Clinical Nutrition · doi:10.1016/j.clnu.2009.04.003 · Cited by 319
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McClave, S. A., Taylor, B. E., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115621863 · Cited by 3,982
American College of Gastroenterology guideline: management of acute pancreatitis
Tenner, S., Baillie, J., DeWitt, J., & Vege, S. S. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.218 · Cited by 2,327
IAP/APA evidence-based guidelines for the management of acute pancreatitis
Working Group IAP/APA Acute Pancreatitis Guidelines (2013) · Pancreatology · doi:10.1016/j.pan.2013.07.063 · Cited by 2,075
Taylor, B. E., McClave, S. A., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001525 · Cited by 1,476
Forsmark, C. E., Vege, S. S., & Wilcox, C. M. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1505202 · Cited by 890
Metadata
- Authors
- Eckerwall, G. E., Tingstedt, B. B. Å., Bergenzaun, P. E., & Andersson, R. G.
- Affiliations
- Skåne University Hospital (SE)
- Corresponding author
- Andersson, Roland G.
- Venue
- Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 26
- Issue
- 6
- Pages
- 758-763
- ISSN
- 0261-5614 (ISSN-L)
- OpenAlex
- W1964043765
- Cited by
- 227
- References
- 27
- Citations by year
- 2026: 8 · 2025: 7 · 2024: 11 · 2023: 11 · 2022: 12 · 2021: 17 · 2020: 10 · 2019: 17 · 2018: 18 · 2017: 18 · 2016: 10 · 2015: 25 · 2014: 11 · 2013: 16 · 2012: 10
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- green
- lup.lub.lu.se
- Licence
- Locations
- Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Gastroenterology › Gallbladder and Bile Duct Disorders
- Keywords
- mild acute pancreatitis, fasting, length of hospital stay, pancreatic amylase, systemic inflammatory response, C-reactive protein, recovery, gastrointestinal tolerance
- MeSH terms
- Adult, Aged, Amylases, C-Reactive Protein, Enteral Nutrition, Fasting, Female, Humans, Inflammation, Length of Stay, Leukocytes, Male, Middle Aged, Pancreas, Pancreatitis, Prospective Studies, Abdominal Pain, Treatment Outcome, APACHE
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