Dose-related meta-analysis for Omega-3 fatty acids supplementation on major adverse cardiovascular events

Markozannes, Georgios; Ntzani, Evangelia E.; Tsapas, Apostolos; Mantzoros, Christos S.; Tsiara, Stavroula; Xanthos, Theodoros; Karpettas, Nikos; Patrikios, Ioannis; Rizos, Evangelos C.

doi:10.1016/j.clnu.2022.02.022

Dose-related meta-analysis for Omega-3 fatty acids supplementation on major adverse cardiovascular events

BACKGROUND & AIMS Omega-3 supplements are widely used for cardiovascular (CV) protection. We performed an updated meta-analysis for omega-3 and CV outcomes. METHODS Random-effects meta-analysis including double-blind RCTs with duration ≥1 year, evaluating omega-3 supplements in 4 a priori defined…