Maternal infection and adverse fetal and neonatal outcomes
Open accessAbstract
Adverse pregnancy outcomes can follow direct placental, fetal, or neonatal infection, or preterm birth associated with vaginal, cervical, intrauterine, or even nonpelvic infections. These latter infections appear to be associated with the majority of very early preterm births, and may explain some of the long-term neurologic damage associated with preterm birth. Bacterial vaginosis and its associated intrauterine infections likely contribute far more to the overall burden of adverse pregnancy outcomes than the more classical perinatal infections such as rubella and syphilis.
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Vaginal group B streptococcus, U urealyticum, and M hominus colonisations are not associated with increased risk of preterm birth.
“Vaginal group B streptococcus, U urealyticum, and M hominus colonisations are not associated with increased risk of preterm birth.103, 104”
From Epidemiology and causes of preterm birth (2008) · cites this paper as [103]
Several non-genital tract infections, such as pyelonephritis, asymptomatic bacteriuria, pneumonia, and appendicitis, are associated with and probably predispose to preterm birth.
“Several non-genital tract infections, such as pyelonephritis and asymptomatic bacteriuria, pneumonia, and appendicitis, are associated with, and probably predispose to, preterm birth.103, 108”
From Epidemiology and causes of preterm birth (2008) · cites this paper as [103]
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References 192 · Cited by 186
Research works printed but not linked: 5
- [25]Horn P. Poliomyelitis in pregnancy. A twenty-year report from Los Angeles County, California Obstet Gynecol 6 1955 121 137 13244968
- [40]Stanley F. Social and biological determinants of the cerebral palsies Stanely F. Alberman E. Clinics in developmental medicine no. 87; the epidemiology of the cerebral palsies 1984 Spastics International Medical Publications, Great Britain, Lavenham Press Ltd. Lavenham, Suffolk 69 86
- [94]Gibbs R.S. Romero R. Hillier S.L. A review of premature birth and subclinical infection Am J Obstet Gynecol 166 1992 1515 1528 1595807
- [135]Goldenberg R.L. Andrews W.W. Yuan A. Pregnancy outcome related to sexually transmitted diseases Hitchcock P.J. MacKay H.T. Wasserheit J.N. Sexually transmitted diseases and adverse outcomes of pregnancy 1999 ASM Press Washington (DC) 1 24 9099500
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- Authors
- Goldenberg, R. L., Culhane, J. F., & Johnson, D. C.
- Affiliations
- University of Alabama at Birmingham (US)
- Drexel University (US)
- Corresponding author
- Goldenberg, Robert L.
- Venue
- Clinics in Perinatology
- Publisher
- Elsevier BV
- Published
- 2005-09
- Volume
- 32
- Issue
- 3
- Pages
- 523-559
- ISSN
- 0095-5108 (ISSN-L)
- PMC
- PMC7119141
- OpenAlex
- W2159732325
- Cited by
- 186
- References
- 192
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 14 · 2023: 12 · 2022: 11 · 2021: 9 · 2020: 4 · 2019: 3 · 2018: 8 · 2017: 4 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 7 · 2012: 17
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinics in Perinatology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Neonatal and Maternal Infections
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- maternal infection, adverse pregnancy outcomes, preterm birth, bacterial vaginosis, intrauterine infection, placental infection, fetal infection, neonatal infection, perinatal infection, rubella, syphilis, neurologic damage
- MeSH terms
- Female, Fetal Diseases, Genital Diseases, Female, Humans, Infant, Newborn, Infant, Newborn, Diseases, Pregnancy, Pregnancy Complications, Infectious, Pregnancy Outcome
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