Can dietary nitrates enhance the efficiency of mitochondria?
Open accessAbstract
A decline in mitochondrial function occurs in many conditions. A report in this issue of Cell Metabolism (Larsen et al., 2011) shows that dietary inorganic nitrates enhance muscle mitochondrial efficiency. It is an attractive hypothesis that dietary changes enhance energy efficiency, but its potential application depends on long-term studies investigating net benefits versus adverse effects.
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S-nitrosylation is associated with activation of transcription factors, regulation of signal transduction molecules, redox protein modification, mitochondrial functions, and cell apoptosis.
“S-nitrosylation is associated with the activation of transcription factors, the regulation of a number of signal transduction molecules [10] and redox protein modification [11], mitochondrial functions [12,13], and cell apoptosis [14]”
From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [13]
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References 10 · Cited by 13
- Authors
- Nair, K. S., Irving, B. A., & Lanza, I. R.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Nair, K. Sreekumaran
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 13
- Issue
- 2
- Pages
- 117-118
- ISSN
- 1550-4131 (ISSN-L)
- PMC
- PMC3049330
- OpenAlex
- W2059111731
- Cited by
- 13
- References
- 10
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Civil War Book Review (submittedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK041973)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Keywords
- dietary nitrate, inorganic nitrate, mitochondrial efficiency, muscle mitochondria, energy metabolism, dietary supplementation
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