Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas
Rodriguez-Diaz, Rayner, Abdulreda, Midhat H., Formoso, Alexander L., Gans, Itai, Ricordi, Camillo, Berggren, Per-Olof, Caicedo, Alejandro·2011·Cell Metabolism
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- Recapitulating and Deciphering Human Pancreas Development From Human Pluripotent Stem Cells in a DishMaja Borup Kjær Petersen, Carla A. Gonçalves, Yung Hae Kim, Anne Grapin‐Botton · 2018 · Current topics in developmental biology/Current Topics in Developmental Biology
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- Neurotransmitters act as paracrine signals to regulate insulin secretion from the human pancreatic isletR. Rodriguez-Diaz, D. Menegaz, A. Caicedo · 2014 · Journal of Physiology
- Structure, interaction and nervous connectivity of beta cell primary ciliaAndreas Müller, Nikolai Klena, Song Pang, Leticia Elizabeth Galicia Garcia, Oleksandra Topcheva, Solange Aurrecoechea Duran, Davud Sulaymankhil, Monika Seliskar, H. Mziaut, Eyke Schöniger et al. · 2024 · bioRxiv
- Islet–immune interactions in type 1 diabetes: the nexus of beta cell destructionLeeana D. Peters, A. Posgai, T. Brusko · 2019 · Clinical and Experimental Immunology
- Pancreatic Islet Blood Flow Dynamics in PrimatesJuan A. Diez, R. Drigo, Xiao-Feng Zheng, O. Stelmashenko, Minni Chua, R. Rodriguez-Diaz, Masahiro Fukuda, Martin Köhler, I. Leibiger, S. B. B. Tun et al. · 2017 · Cell Reports
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- Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and FunctionE.S. Di Cairano, S. Moretti, Paola Marciani, Vellea Franca Sacchi, Michela Castagna, Alberto M. Davalli, Franco B. Folli, Carla Perego · 2015 · Journal of Cellular Physiology
- GDNF is required for neural colonization of the pancreasJ. L. Muñoz-Bravo, M. Hidalgo-Figueroa, A. Pascual, J. López-Barneo, A. Leal-Cerro, D. Cano · 2013 · Development
- Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetesZuxin Chen, Xin-An Liu, P. Kenny · 2023 · Pharmacological Research
- Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammationHan Xie, Natesh Yepuri, Q. Meng, R. Dhawan, C. A. Leech, O. Chepurny, G. G. Holz, R. Cooney · 2020 · Reviews in Endocrine & Metabolic Disorders
- MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 DiabetesGanic, Elvira, Singh, Tania, Luan, Cheng, Fadista, João, Johansson, Jenny K., Cyphert, Holly Ann, Bennet, Hedvig, Storm, Petter, Prost, Gaëlle, Ahlenius, Henrik et al. · 2016 · Cell Reports
- Islets Have a Lot of Nerve! Or Do They?G. Taborsky · 2011 · Cell Metabolism
- Molecular and functional diversity of the autonomic nervous systemTongtong Wang, Avedis Tufenkjian, O. Ajijola, Yuki Oka · 2025 · Nature Reviews Neuroscience
- Mapping and targeted viral activation of pancreatic nerves in mice reveal their roles in the regulation of glucose metabolismM. Jimenez-Gonzalez, R. Li, L. Pomeranz, A. Alvarsson, R. Marongiu, R. F. Hampton, M. Kaplitt, R. Vasavada, G. Schwartz, S. Stanley · 2022 · Nature Biomedical Engineering
- Inter-organ communication and regulation of beta cell functionMehboob Ali Hussain, Elina Akalestou, Woo‐Jin Song · 2016 · Diabetologia
- Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans isletsPetr Bušek, Petr Hrabal, Premysl Fric, Aleksi Šedo · 2014 · Histochemistry and Cell Biology
- Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 DiabetesJoseph S. Canzano, Lith Nasif, E. Butterworth, Dong-Tao A. Fu, M. Atkinson, M. Campbell-Thompson · 2018 · Journal of Histochemistry and Cytochemistry
- Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD miceLaurits J. Holm, Martin Haupt-Jorgensen, J. D. Giacobini, J. Hasselby, M. Bilgin, K. Buschard · 2019 · Diabetologia
- Co-transplantation of human pancreatic islets with post-migratory neural crest stem cells increases β-cell proliferation and vascular and neural regrowth.Liza Grapensparr, S. Vasylovska, Zhanchun Li, J. Olerud, L. Jansson, E. Kozlova, P. Carlsson · 2015 · Journal of Clinical Endocrinology and Metabolism
- Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRHCraig S. Nunemaker, L. Satin · 2014 · Endocrine
- TRPV1 neurons regulate β-cell function in a sex-dependent mannerJoey Bou Karam, Wei-Kang Cai, Rowaida Mohamed, Tianwen Huang, L. Meng, Erica P. Homan, E. Dirice, C. R. Kahn, A. El Ouaamari · 2018 · Molecular Metabolism
- NOVEL APPROACHES TO STUDY THE ROLE INNERVATION PLAYS IN THE BIOLOGY OF PANCREATIC ISLETSR. Rodriguez-Diaz, A. Caicedo · 2012 · Endocrinology and metabolism clinics of North America (Print)
- Vesicular monoamine transporter, type 2 (vmat2) expression as it compares to insulin and pancreatic polypeptide in the head, body and tail of the human pancreasMatthew Freeby, Masanori Ichise, Paul E. Harris · 2012 · Islets
- One-step purification of functional human and rat pancreatic alpha cells.Martin Köhler, E. Daré, M. Ali, Subu Surendran Rajasekaran, T. Moede, B. Leibiger, I. Leibiger, A. Tibell, L. Juntti-Berggren, P. Berggren · 2012 · Integrative Biology
- β-Cell Function in Obese-Hyperglycemic Mice [ob/ob Mice]Per Lindström · 2010 · Advances in experimental medicine and biology
- Pancreas-Brain CrosstalkB. Lkhagvasuren, Onanong Mee-inta, Zi-Wei Zhao, Tetsuya Hiramoto, D. Boldbaatar, Yu-Min Kuo · 2021 · Frontiers in Neuroanatomy
- Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signallingThomas Aga Legøy, Heidrun Vethe, Shadab Abadpour, Berit Løkensgard Strand, Hanne Scholz, João A. Paulo, Helge Ræder, Luiza Ghila, Simona Chera · 2020 · Scientific Reports
- The pancreatic islet as a signaling hub.C. J. Barker, I. Leibiger, P. Berggren · 2013 · Advances in Biological Regulation
- Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived isletsMyungji Kim, Seungyeun Cho, D. G. Hwang, I. Shim, Song Cheol Kim, Jiwon Jang, Jin-Ah Jang · 2025 · Nature Communications
- Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion.B. Thorens · 2024 · Physiological Reviews
- The Sympathetic‐Immune Milieu in Metabolic Health and Diseases: Insights from Pancreas, Liver, Intestine, and Adipose TissuesWenran Ren, Meng-Lu Hua, Fang Cao, Wen-Wen Zeng · 2023 · Advancement of science
- Surface Coating of Pancreatic Islets with Neural Crest Stem Cells Improves Engraftment and Function after Intraportal TransplantationJ. Lau, S. Vasylovska, E. Kozlova, P. Carlsson · 2015 · Cell Transplantation
- HGAL localization to cell membrane regulates B-cell receptor signaling.Xiao-Qing Lu, R. Sicard, Xiao-Yu Jiang, Jessica N. Stockus, G. McNamara, M. Abdulreda, V. Moy, R. Landgraf, I. Lossos · 2015 · Blood
- Pericyte Control of Blood Flow in Intraocular Islet Grafts Impacts Glucose Homeostasis in MiceAlejandro Tamayo, L. Gonçalves, R. Rodriguez-Diaz, Elizabeth Pereira, Melissa Canales, A. Caicedo, J. Almaça · 2022 · Diabetes
- 5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasisXiaozhe Zhang, Na Li, Jun Zhang, Yanshen Zhang, Xiao-Li Yang, Yifan Luo, Bobo Zhang, Zhixue Xu, Zhenhua Zhu, Xiu-Yan Yang et al. · 2021 · Nature Metabolism
- Islet nerves in focus—defining their neurobiological and clinical roleAh-Ren Bo · 2012 · Diabetologia
- Induction of differentiation of undifferentiated cells into pancreatic beta cells in vertebrates.M. Hosoya, Yuya Kunisada, A. Kurisaki, M. Asashima · 2012 · International Journal of Developmental Biology
- Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity ChangesXin Tong, Roland W. Stein · 2021 · Diabetes
- Intraocular in vivo imaging of pancreatic islet cell physiology/pathologyI. Leibiger, P. Berggren · 2017 · Molecular Metabolism
- Metabolic and functional heterogeneity in pancreatic β cells.G. da Silva Xavier, G. Rutter · 2020 · Journal of Molecular Biology
- Pancreatic Schwann cell reprogramming supports cancer-associated neuronal remodelingMartha M. Rangel-Sosa, Fanny Mann, Sophie Chauvet · 2023 · bioRxiv
- Optical Imaging of Pancreatic InnervationM. Makhmutova, A. Caicedo · 2021 · Frontiers in Endocrinology
- Functional Characterization of the Human Islet Microvasculature Using Living Pancreas SlicesLuciana Mateus Gonçalves, J. Almaça · 2021 · Frontiers in Endocrinology
- Cellular and systemic mechanisms for glucose sensing and homeostasisJong-Woo Sohn, W. Ho · 2020 · Pflügers Archiv: European Journal of Physiology
- Mass production of functional human pancreatic β‐cells: why and how?R. Scharfmann, M. Didiesheim, Paul Richards, V. Chandra, Masaya Oshima, O. Albagli · 2016 · Diabetes, obesity and metabolism
- Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and AnalysisJ. Dolenšek, Denis Spelic, Maša Skelin Klemen, B. Žalik, M. Gosak, Marjan Slak Rupnik, A. Stožer · 2015 · Italian National Conference on Sensors
- Ontogeny of Neuro-Insular Complexes and Islets Innervation in the Human PancreasA. Proshchina, Yulia S. Krivova, V. Barabanov, S. Saveliev · 2014 · Frontiers in Endocrinology
- The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetesM. Lundberg, A. Lindqvist, N. Wierup, L. Krogvold, K. Dahl-Jørgensen, Oskar Skog · 2017 · PLoS ONE
- Nicotinic Cholinergic Signaling in Adipose Tissue and Pancreatic Islets Biology: Revisited Function and Therapeutic PerspectivesEmmanuel Somm · 2013 · Archivum Immunologiae et Therapiae Experimentalis
- The ductal origin of structural and functional heterogeneity between pancreatic islets.C. Merkwitz, O. Blaschuk, A. Schulz, P. Lochhead, J. Meister, Angela Ehrlich, A. Ricken · 2013 · Progress in Histochemistry and Cytochemistry
- Pancreatic Ductal Adenocarcinoma Induces Neural Injury that Promotes a Transcriptomic and Functional Repair Signature by Peripheral NeurogliaJonathan R. Weitz, Bharti Garg, A. Martsinkovskiy, S. Patel, Hervé Tiriac, A. Lowy · 2023 · Oncogene
- A new mode of pancreatic islet innervation revealed by live imaging in zebrafishYu Hsuan Carol Yang, Koichi Kawakami, Didier Y. R. Stainier · 2018 · eLife
- A novel toolbox to investigate tissue spatial organization applied to the study of the islets of LangerhansHoa Tran Thi Nhu, R. A. Drigo, P. Berggren, T. Boudier · 2017 · Scientific Reports
- The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1.Astrid Plamboeck, S. Veedfald, C. Deacon, B. Hartmann, T. Vilsbøll, F. Knop, J. Holst · 2015 · American Journal of Physiology. Regulatory Integrative and Comparative Physiology
- Neural Regulation of Pancreatic Cancer: A Novel Target for InterventionAeson Chang, Corina Kim-Fuchs, Caroline P. Le, Frédéric Hollande, Erica K. Sloan · 2015 · Cancers
- The p75 Neurotrophin Receptor Is Required for the Major Loss of Sympathetic Nerves From Islets Under Autoimmune AttackG. Taborsky, Q. Mei, K. Bornfeldt, D. J. Hackney, T. Mundinger · 2014 · Diabetes
- Heterogeneity and Dynamics of Vasculature in the Endocrine System During Aging and DiseaseSina Stücker, Jessica E. De Angelis, Anjali P. Kusumbe · 2021 · Frontiers in Physiology
- Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans.F. Cinti, T. Mezza, I. Severi, M. Suleiman, C. M. A. Cefalo, G. Sorice, Simona Moffa, F. Impronta, G. Quero, Sergio Alfieri et al. · 2020 · Metabolism: Clinical and Experimental
- The Role of Accessory Cells in Islet HomeostasisShiue-Cheng Tang, C. Jessup, M. Campbell-Thompson · 2018 · Current Diabetes Reports
- Histology of Type 1 Diabetes Pancreas.A. Willcox, K. Gillespie · 2015 · Methods in molecular biology
- Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of Langerhans of obese miceI. Giannulis, E. Mondini, F. Cinti, A. Frontini, I. Murano, R. Barazzoni, G. Barbatelli, Domenico Accili, S. Cinti · 2013 · NMCD. Nutrition Metabolism and Cardiovascular Diseases
- Islet inflammation in plain sightM. Abdulreda, Per-Olof Berggren · 2013 · Diabetes, obesity and metabolism
- Innervation of the pancreas in development and disease.Rikke Agerskov, Pia Nyeng · 2024 · Development
- Vagal pathways for systemic regulation of glucose metabolismDiba Borgmann, Henning Fenselau · 2023 · Seminars in Cell and Developmental Biology
- Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoisletsE. Lorza-Gil, F. Gerst, M. B. Oquendo, U. Deschl, H. Häring, Mario Beilmann, S. Ullrich · 2019 · Scientific Reports
- The combination of GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitusSara Chowdhury, Songyan Wang, Bruce W. Patterson, Dominic N. Reeds, Burton M. Wice · 2013 · Regulatory Peptides
- Evidence for a Neogenic Niche at the Periphery of Pancreatic IsletsMark O. Huising, Sharon Lee, Talitha van der Meulen · 2018 · BioEssays
- Roles of Pancreatic Islet Catecholamine Neurotransmitters in Glycemic Control and in Antipsychotic Drug–Induced DysglycemiaZachary Freyberg, George K. Gittes · 2022 · Diabetes
- NOD Mice—Good Model for T1D but Not Without LimitationsV. Aldrich, Barbara Hernandez-Rovira, Ankita Chandwani, M. Abdulreda · 2020 · Cell Transplantation
- Temporal and Spatial Cellular Distribution of Neural Crest Derivatives and Alpha Cells during Islet DevelopmentKousuke Shimada, T. Tachibana, Kei Fujimoto, Takashi Sasaki, M. Okabe · 2012 · Acta Histochemica et Cytochemica
- Cholinergic signaling mediates the effects of xenin-25 on secretion of pancreatic polypeptide but not insulin or glucagon in humans with impaired glucose toleranceSong-Yan Wang, Lauren Z. Oestricker, M. Wallendorf, K. Sterl, J. Dunai, C. Kilpatrick, B. Patterson, Dominic N. Reeds, B. Wice · 2018 · PLoS ONE
- Morphologic Changes in Autonomic Nerves in Diabetic Autonomic NeuropathyHeung Y. Jin, H. Baek, T. Park · 2015 · Diabetes & Metabolism Journal
- A Receptor Story: Insulin Resistance Pathophysiology and Physiologic Insulin Resensitization’s Role as a Treatment ModalityStanley T. Lewis, Frank L. Greenway, Tori R. Tucker, Michael Alexander, Levonika K. Jackson, Scott A. Hepford, Brian Loveridge, Jonathan R. T. Lakey · 2023 · International Journal of Molecular Sciences
- Neonatal Diabetes in Patients Affected by Liang-Wang Syndrome Carrying KCNMA1 Variant p.(Gly375Arg) Suggest a Potential Role of Ca2+ and Voltage-Activated K+ Channel Activity in Human Insulin SecretionC. Mameli, R. Cazzola, L. Spaccini, V. Calcaterra, M. Macedoni, P. A. La Verde, E. D'Auria, E. Verduci, G. Lista, G. Zuccotti · 2021 · Current Issues in Molecular Biology
- Autonomic nervous system and pancreatic islet blood flow.L. Pénicaud · 2017 · Biochimie
- β‐Cell biology of insulin secretionD. M. Sci. Susumu Seino, T. Shibasaki, K. Minami · 2015 · Wiley eBooks
- PGP 9.5 immunocytochemical staining for pancreatic endocrine tumorsT. Tomita · 2013 · Islets
- The Different Faces of the Pancreatic IsletM. Abdulreda, R. Rodriguez-Diaz, Over Cabrera, A. Caicedo, P. Berggren · 2016 · Advances in Experimental Medicine and Biology
- Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencingTingting Yang, Chao-Ying Yan, Lan Yang, Jiang Tan, Shiqiu Jiang, Juan Hu, Wei Gao, Qiang Wang, Yan-Song Li · 2023 · European Journal of Medical Research
- α-cell electrophysiology and the regulation of glucagon secretionRui Gao, Samuel Acreman, Jinfang Ma, Fernando Abdulkader, Anna Wendt, Quan Zhang · 2023 · Journal of Endocrinology
- Prenatal development of sympathetic innervation of the human pancreasYuliya S. Krivova, A. E. Proshchina, Dmitry Otlyga, Olga G. Leonova, Sergey V. Saveliev · 2021 · Annals of Anatomy - Anatomischer Anzeiger
- Role of islet peptides in beta cell regulation and type 2 diabetes therapy.D. Khan, C. Moffet, P. Flatt, C. Kelly · 2018 · Peptides
- β-Cell Generation: Can Rodent Studies Be Translated to Humans?Françoise Carlotti, Arnaud Zaldumbide, Johanne H. Ellenbroek, H. Siebe Spijker, Rob C. Hoeben, Eelco J.P. de Koning · 2011 · Journal of Transplantation
- Interorgan crosstalk in pancreatic islet function and pathologyRonald M. Evans, Zong Wei · 2022 · FEBS Letters
- Coordinated dual-hormone artificial pancreas with parallel control structureVanessa Moscardó, Pau Herrero, José-Luis Díez, Marga Giménez, Paolo Rossetti, Pantelis Georgiou, Jorge Bondía · 2019 · Computers & Chemical Engineering
- The Eye as a Transplantation Site to Monitor Pancreatic Islet Cell PlasticityE. Ilegems, P. Berggren · 2021 · Frontiers in Endocrinology
- Beta-cell function and human islet transplantation: can we improve?Jennifer Hechao Chen, Jenny Elizabeth Gunton · 2021 · Journal of Endocrinology
- Neuroimmunometabolic co-evolution in the tumor micro- and macroenvironment.Yu Zhang, Weijie Zhuang, Haodong Zhu, Fan-Sheng Meng, Ming-Tao Chen, Yi-Bo Guo, Jia Fan, Yun-Fan Sun, Tong Ji · 2026 · Cell Metabolism
- Schwann Cells in Digestive System DisordersK. Goluba, Liga Kunrade, U. Riekstiņa, V. Parfejevs · 2022 · Cells
- The Feasibility and Applicability of Stem Cell Therapy for the Cure of Type 1 DiabetesRyota Inoue, Kuniyuki Nishiyama, Jinghe Li, Daisuke Miyashita, Masato Ono, Yasuo Terauchi, Jun Shirakawa · 2021 · Cells
- The pancreatic islet: a micro-organ in controlM. Abdulreda, P. Berggren · 2021 · CellR4-- repair, replacement, regeneration, & reprogramming
- Parallel Control of an Artificial Pancreas with Coordinated Insulin, Glucagon, and Rescue Carbohydrate Control ActionsVanessa Moscardó, José-Luis Díez, Jorge Bondía · 2019 · Journal of Diabetes Science and Technology
- Synchronization of pancreatic islets by periodic or non-periodic muscarinic agonist pulse trainsJoel E Adablah, R. Vinson, Michael G. Roper, R. Bertram · 2019 · PLoS ONE
- Cholinergic anti-inflammatory pathway in the non-obese diabetic mouse model.F. Koopman, J. Vosters, N. Roescher, N. Broekstra, P. Tak, M. Vervoordeldonk · 2015 · Oral Diseases
- Neurofunctional Imaging of β-Cell DynamicsPaul E. Harris, R. Leibel · 2012 · Diabetes, obesity and metabolism